Family-friendly vacation rentals in Mission Bay

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Top-rated family-friendly rentals in Mission Bay

Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

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Top guest favorite
A bright living space features a large sectional sofa adorned with orange cushions, complemented by a colorful area rug. A wooden coffee table sits in front, and a wall-mounted art piece adds a touch of elegance. Large windows provide skyline views and abundant natural light.
Loft in South of Market
4.98 out of 5 average rating, 145 reviews

Inspiring Skyline Views From a Hip Loft in SoMa

Brew coffee in a kitchen with bold wood cabinets, then curl up with a book on a cushioned bench set along floor-to-ceiling windows offering skyline views. Modern furnishings and colorful decor forge a trendy vibe within this bright loft apartment. The loft has all imported fixtures and finishes from Italy. It has Ralph Lauren deep brown carpet on the stairs and in the bedroom/office and polished concrete on the main level. There is also remote controlled blinds on the main windows and skylights. Access to the whole area described in the Summary. I can be available 24/7 at least the first and last day of their stay. Though likely at all times. The South of Market (SoMa) neighborhood has a lot of restaurants, bars and night clubs to enjoy. It is also very close to the Moscone Center. 3 1/2 blocks away from Civic Center BART/Muni Station. 20 minute walk to downtown. 4 blocks away from Moscone Center. 20 minute walk to AT&T Park SoMa is a hip neighborhood with a ton of restaurants to choose from, bars and night clubs, start-up companies around, close to the Moscone Center.

Top guest favorite
A spacious bedroom is illuminated by natural light, featuring a minimalist wooden bed with gray bedding. A large artwork hangs above the bed, while a potted plant and small reading lamp add detail. A desk and chair are positioned nearby, enhancing the workspace.
Guest suite in Mission
5 out of 5 average rating, 205 reviews

Large Light Filled Quiet Artist built 2BR Apt

Large, light filled, quiet, private 2 bedroom apartment/guest suite with split bathroom (toilet and sink in one room, soaking tub/shower and sink in other), kitchenette, and ceilings up to 16'. We have been working on this space for the last 2 years to get the details just right, including hand built furniture and art by local artists. Above the din of the Mission, this apartment is a unique space built in the attic of a large Edwardian house run by artists Laurel Roth Hope and Andy Diaz Hope .

Top guest favorite
A cozy living area features a gray sofa adorned with a patterned throw blanket and colorful cushions. Two round coffee tables are positioned on a textured rug. The wall displays framed records and art, while a coffee bar is set up against the opposite wall.
Guest suite in San Francisco
4.98 out of 5 average rating, 238 reviews

Urban oasis! Deck, city views, entire place

Welcome to San Francisco! Looking for the perfect place to stay while visiting the city? Look no further than this charming and contemporary studio that offers panoramic views of the city's skyline and a glimpse of the iconic GG Bridge from your private deck. Located just a short walk from Mission, you'll be able to explore the city easily. Whether you're in town for business or pleasure, this urban paradise will make you feel right at home. A bonus - easy street parking! Book your stay today!

Guest favorite
An open living area features a grey sectional sofa with a patterned throw and a coffee table. A sleek black TV stand supports an HD television. The modern kitchen, observed in the background, includes stainless steel appliances and a wooden bar with seating, enhancing the space's functionality.
Home in Potrero Hill
4.86 out of 5 average rating, 104 reviews

Spacious, stylish, cozy 1 bedroom in Potrero Hill

Just 15 minutes from downtown SF and the SFO airport, this cozy, spacious 1 bedroom apt is the ultimate way to enjoy San Francisco. In Potrero Hill, the sunniest part of SF, the sidewalk level 1 bedroom has modern furnishings and its own private entrance, living room, kitchen, bedroom and bath. Walking distance to bus lines, it is a peaceful and relaxing getaway from the bustling city. A booklet is provided on recommendations on restaurants, places to visit, activities, and transportation!

Top guest favorite
A comfortable sleeping area features a plush bed with soft linens and a decorative throw, complemented by a colorful accent pillow. A stylish couch sits across from the bed, adorned with throws and cushions, while a wall shelf displays books and decorative items, enhancing the inviting space.
Guesthouse in Mission
4.98 out of 5 average rating, 102 reviews

Safe, modern & newly renovated – a hidden gem

Welcome to our newly renovated Carriage House in the heart of San Francisco! This charming two-story retreat offers modern amenities with historic character. Enjoy a fully stocked kitchenette, live/work space, and comfortable beds, perfect for families or groups. Located between the vibrant Mission and Potrero Hill neighborhoods, you’re steps away from trendy cafes, shops, and venues. Whether you’re here for work or leisure, our space provides a private, peaceful escape in a prime location.​

Top guest favorite
A modern studio space showcases a comfy bed adorned with neutral-toned bedding. A small dining table is accompanied by stylish chairs. Large windows allow for ample natural light, while greenery is visible outside. A sleek couch and minimalist decor complete the welcoming atmosphere.
Guest suite in San Francisco
4.96 out of 5 average rating, 208 reviews

Modern Bernal Heights studio-Private outdoor patio

Welcome to my modern studio with private entrance, walk-in closet, bathroom, kitchenette, and peaceful outdoor space with outdoor dining set, grill, and lounge chairs. Located on a quiet street in the Bernal Heights area and a 5min walk to Bernal Hill outdoor space, 20min walk to the shops, bars/restaurants on Cortland Avenue, 10min walk from Precita Park with local cafes, grocery store, & beautiful Park. It’s HILLY Note. kitchenette is outside the unit in private closed-off space in garage

Guest favorite
A clean and modern sleeping area features a wooden headboard with two large white pillows resting on a queen-sized bed. Above, a circular woven wall decoration adds texture and warmth to the minimalist setup.
Apartment in Potrero Hill
4.84 out of 5 average rating, 140 reviews

Stylish & quiet studio apartment in Potrero Hill

*FEATURED IN SUNSET MAGAZINE* Welcome to scenic Potrero Hill! Our studio apt has a private entrance & is perfect for city visitors. It sleeps 2, in 1 brand new queen sized bed with a comfy new Nest organic mattress. Our guest studio apartment is newly renovated with brand new modern furniture, super clean and stylish bathroom, and mini kitchen. It has a hot water kettle, sink, minibar style fridge and plates & utensils. Fresh bed linen and towels on arrival and a stock of coffee & tea

Top guest favorite
The spacious room features a large bed with a light throw and decorative pillows. A comfortable armchair and a small table are positioned near the sliding glass door that opens to the backyard. Light wood flooring and soft area rugs add warmth to the space.
Guest suite in San Francisco
4.95 out of 5 average rating, 440 reviews

Northslope Studio in Bernal Heights with a Zen, Leafy Patio

Wake up to the soothing green view from this recently remodeled (mid-2023) studio nestled on a sleepy block in Bernal Heights. A peaceful backyard with a Buddha sculpture and a modernist inspired courtyard sit alongside the bedroom, kitchenette and bathroom. Free street parking (parallel) is available on my block and surrounding streets, not restricted, and typically easily available. Note that the in-law studio shares a common front door and foyer with the main house upstairs.

Top guest favorite
The living area features a spacious gray sectional sofa complemented by a vibrant area rug. Sunlight filters through tall windows adorned with shutters, illuminating the room. A decorative wall sculpture and indoor plants add visual interest, while a fireplace offers a cozy focal point.
Loft in South of Market
4.99 out of 5 average rating, 393 reviews

Near Moscone Ctr, Privacy with Style the SoMa Loft

Total privacy in two levels space-business friendly - smoke free building and unit. The entry level (living area) and mezzanine (bedroom and master bath) Shared Courtyard (Building common area.) South of Market is one of the most diversified neighborhoods in San Francisco, close to everywhere. Walking distance to Moscone Ctr, MoMa, AT&T Park and Union Square. SoMa Second Home is surrounded by cafes, restaurants, breweries, clubs and shops. - Bike Score - 96 (Biker's Paradise)

Guest favorite
A bright dining area features a wooden table surrounded by black chairs. Large windows and skylights allow natural light to fill the space. Green plants are displayed, and a cozy seating nook with cushions is visible. A sliding door leads to a deck area.
Home in Potrero Hill
4.96 out of 5 average rating, 253 reviews

2br Victorian House with Breathtaking views

Amazing Victorian House on top of Potrero Hill one of the best places in San Francisco to have a magnificent view of the city. Spacious house with terrace and garden. Fast Wifi, parking for free 24/7, smart tvs with fire stick. Very close to downtown, the Mission, Castro, Ferry building, AT&T Giants, Chase Center, general hospital, UCSF, just 15 minutes from the airport. Great restaurants, wineries, parks and the historic Anchor Steam Factory in the neighborhood.

Top guest favorite
A bright living area features large bay windows fitted with bamboo shades, allowing natural light to flood the space. A plush sectional sofa is complemented by a round glass table and artful decor, including framed artwork and decorative urns on pedestal shelves.
Apartment in Potrero Hill
4.98 out of 5 average rating, 574 reviews

Fabulous Artist Flat in the Heart of Potrero Hill

Decorated in the eclectic bohemian spirit of San Francisco, the living space is filled with original artwork, vibrant colors and souvenirs from travel. The flat, with its easy-going creative vibe, could be the place you discover inspiration for your next project. The flat is clean, comfortable and filled with eclectic artistic touches to the delight of our guests. Please no shoes worn inside.

Guest favorite
A bright and airy living space features a unique circular rug with warm tones and a modern dining table surrounded by stylish chairs. Decorative plants enhance the natural light, while a wall-mounted TV and sound system provide entertainment options.
Apartment in Potrero Hill
4.89 out of 5 average rating, 114 reviews

2BR Penthouse with 4 sunny decks

Beautiful, modern 2 bedroom, 2 bath flat with 4 decks, high ceilings and sunny skylights, home automation system, all the appliances you could need in the kitchen and Sonos throughout the house. Upstairs office with a terrific view for working. Near the 22 and 55 MUNI buses. Our approved STR license is #STR-0006637

Popular amenities for Mission Bay family-friendly rentals

Quick stats about vacation rentals that are family-friendly in Mission Bay

  • Total vacation rentals

    Explore 20 vacation rentals in Mission Bay

  • Nightly prices starting at

    Mission Bay vacation rentals start at G$31,380 GYD per night before taxes and fees

  • Verified guest reviews

    Over 150 verified reviews to help you choose

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wi-Fi availability

    20 of Mission Bay vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Mission Bay rentals

  • 4.9 Average rating

    Mission Bay stays are highly rated by guests—averaging 4.9 out of 5!