Family-friendly vacation rentals in Mission Bay

Find and book unique family-friendly homes on Airbnb

Quick stats about vacation rentals that are family-friendly in Mission Bay

  • Total vacation rentals

    Explore 10 vacation rentals in Mission Bay

  • Nightly prices starting at

    Mission Bay vacation rentals start at G$37,660 GYD per night before taxes and fees

  • Verified guest reviews

    Over 260 verified reviews to help you choose

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wi-Fi availability

    10 of Mission Bay vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Mission Bay rentals

  • 5 Average rating

    Mission Bay stays are highly rated by guests—averaging 5 out of 5!

Top-rated family-friendly rentals in Mission Bay

Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

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Top guest favorite
A comfortable sleeping area features a plush bed with soft linens and a decorative throw, complemented by a colorful accent pillow. A stylish couch sits across from the bed, adorned with throws and cushions, while a wall shelf displays books and decorative items, enhancing the inviting space.
Guesthouse in Potrero Hill

Safe, modern & newly renovated – a hidden gem

Welcome to our newly renovated Carriage House in the heart of SF! This charming 2-story retreat offers modern amenities, historic character, a stocked kitchenette, live/work space, and comfortable beds. Located between the Mission and Potrero Hill, you’re close to cafes, shops, and venues. We live on site in main residence and share the property during guest stays. Whether you’re here for work or leisure, our place is a fully detached, private building, offering complete seclusion and privacy.

Indoor spacesKitchenAccess

4.98 out of 5 average rating, 140 reviews
Guest favorite
Home in Potrero Hill

Spacious, stylish, cozy 1 bedroom in Potrero Hill

Just 15 minutes from downtown SF and the SFO airport, this cozy, spacious 1 bedroom apt is the ultimate way to enjoy San Francisco. In Potrero Hill, the sunniest part of SF, the sidewalk level 1 bedroom has modern furnishings and its own private entrance, living room, kitchen, bedroom and bath. Walking distance to bus lines, it is a peaceful and relaxing getaway from the bustling city. A booklet is provided on recommendations on restaurants, places to visit, activities, and transportation!

Indoor spacesFamilyQuiet

4.86 out of 5 average rating, 128 reviews
Superhost
A well-lit room features a spacious bed covered with white linens, creating a clean and modern look. A window with light curtains allows natural light to brighten the space. A small table and a wall-mounted TV are visible, adding to the room's functionality.
Apartment in South of Market

SoMa 9 Residences Room 1 Private Bathroom St View

SOMA (short for South of Market St) is top of the list for where to stay in San Francisco for the first time. SOMA 9 Residences is located in the Heart of SF SOMA District, were you'll find everything from shopping to fine dining, plus landmarks such as Yerba Buena, Moscone convention center, SF MOMA, and steps away to Giants Ballpark. The proximity to Market St. makes SOMA one of the most accessible areas of the city. There's buses and rail lines (called BART) on just about every block.

Indoor spacesKitchenCheckout

4.9 out of 5 average rating, 100 reviews
Superhost
A clean and modern sleeping area features a wooden headboard with two large white pillows resting on a queen-sized bed. Above, a circular woven wall decoration adds texture and warmth to the minimalist setup.
Apartment in Potrero Hill

Stylish & quiet studio apartment in Potrero Hill

*FEATURED IN SUNSET MAGAZINE* Welcome to scenic Potrero Hill! Our studio apt has a private entrance & is perfect for city visitors. It sleeps 2, in 1 brand new queen sized bed with a comfy new Nest organic mattress. Our guest studio apartment is newly renovated with brand new modern furniture, super clean and stylish bathroom, and mini kitchen. It has a hot water kettle, sink, minibar style fridge and plates & utensils. Fresh bed linen and towels on arrival and a stock of coffee & tea

KitchenFamilyAccuracy

4.83 out of 5 average rating, 167 reviews
Guest favorite
A charming two-story house is presented, featuring a striking grey exterior with white trim. Double garage doors are visible at the base, and a series of steps lead to a welcoming front porch. Large windows enhance natural light, and greenery adds a touch of warmth.
Guest suite in Bernal Heights

Live Like a Local in Sunny Bernal Heights

Located close to the Mission and Potrero Hill, our 2 bedroom (approx 1000 sq.ft.) rental is near great restaurants, unique shopping, and the newly opened Chase Center. This 2 bedroom unit is well-stocked with everything you'll need to have a relaxing and fun-filled stay in San Francisco. There's easy access getting into and out of our neighborhood and our street has ample parking. We love to host and are excited to meet new people eager to explore all that the Bay Area has to offer!

KitchenIndoor spacesParks

4.93 out of 5 average rating, 452 reviews
Guest favorite
A well-lit living area features a gray sofa adorned with a rust-colored pillow. A glass coffee table houses small plants and books. Wall art is displayed above. A decorative shelf and a potted plant contribute to the inviting ambiance. A door leads to the exterior.
Guest suite in Mission

Charming Mission Apartment

Newly renovated apartment built in a 130-year-old Marina-style house with a separate entrance from the main house. Two bedrooms, one bath, a fully equipped kitchen, washer, and dryer, and a large smart TV. The apartment has a perfect placement on a quiet street, but close enough to all the great restaurants, coffee shops, and nightlife of the Mission (98 walk score). I live upstairs in the same home and am available during your stay, while guests have full privacy in their own space.

KitchenIndoor spacesDecor

4.94 out of 5 average rating, 130 reviews
Top guest favorite
A bright living area is presented, featuring a spacious sectional sofa paired with a wood coffee table. The modern kitchen is visible in the background, equipped with stainless steel appliances. Vibrant artwork adorns the walls, complementing the open dining space with a wooden table and black chairs.
Home in Potrero Hill

Lux Large 2BR, Separate Entry, New Renovation

Welcome to Potrero Hill! We are the sunniest neighborhood in the city and are perfectly located. Our home is 15 min walk to SF General Hospital, UCSF, Mission Bay, SOMA, and the Mission district. You will get an entire bottom floor of the house, fully separated from our home. Home is brand new, built in 2022. While you have total privacy, we are on site in case anything comes up. Parking is easy and we are near the freeways, making it easy to get to Silicon Valley, Marin, or Napa.

Indoor spacesKitchenQuiet

4.97 out of 5 average rating, 123 reviews
Top guest favorite
A comfortable seating area features a light-colored sofa adorned with decorative cushions and a wooden coffee table. A beige armchair complements the space, while a bookcase showcases various items and framed art adds a personal touch against the soft yellow walls.
Guest suite in Bernal Heights

Audrey & Nick's Place

Audrey and Nick’s place is a comfortable, spacious studio with a private entrance, and all the comforts of home. It is located in the renovated basement of a 19th century farmhouse and is fully apportioned with a queen size bed, a large bathroom with a deep tub and access to both front and back yards. It has all the basics, and then some. It is a perfect base of operations for days and nights on the town or around the Bay and a great place to stay in and get things done.

FamilyIndoor spacesSolo travel

4.93 out of 5 average rating, 343 reviews
Top guest favorite
A bright dining area features a wooden table surrounded by black chairs. Large windows and skylights allow natural light to fill the space. Green plants are displayed, and a cozy seating nook with cushions is visible. A sliding door leads to a deck area.
Home in Potrero Hill

2br Victorian House with Breathtaking views

Amazing Victorian House on top of Potrero Hill one of the best places in San Francisco to have a magnificent view of the city. Spacious house with terrace and garden. Fast Wifi, parking for free 24/7, smart tvs with fire stick. Very close to downtown, the Mission, Castro, Ferry building, AT&T Giants, Chase Center, general hospital, UCSF, just 15 minutes from the airport. Great restaurants, wineries, parks and the historic Anchor Steam Factory in the neighborhood.

FamilyKitchenLocation

4.97 out of 5 average rating, 278 reviews
Top guest favorite
A spacious living area features a comfortable cream-colored sofa with decorative pillows, a round coffee table with a tray, and a light-colored rug. A well-lit sleeping area includes a large bed with neatly arranged linens. A dining table and chairs are visible in the background.
Guest suite in Potrero Hill

Modern Suite with Private Entrance

PRIVATE SUITE WITH SEPARATE ENTRANCE. INCLUDES WIFI, FLAT SCREEN TV (WITH APPS ONLY LIKE NETFLIX, PRIME, & YOUTUBE), LIVING ROOM RUG, COFFEE TABLE, MICROWAVE, AND FRIDGE (NO KITCHEN), BATH & PRIVATE YARD. SPACIOUS WITH CONCRETE FLOORS & A LOT LIGHT. NEW: BLACKOUT BLINDS ON ALL WINDOWS. STREET PARKING IS FREE FOR 4 HRS FROM 8-6PM MON-FRI AND FREE ALL DAY SAT AND SUN. HOUSE IS 1 BLOCK FROM SHOPS / RESTAURANTS. 2 PEOPLE MAX. NO PETS DUE TO ALLERGIES 000035STR

Indoor spacesFamilyAir conditioning

4.83 out of 5 average rating, 389 reviews
Guest favorite
A spacious room features a sleek, modern design with a white sofa adorned with colorful pillows. A striped area rug complements the hardwood floor. Natural light enters through a door leading outside, while a flat-screen TV is mounted on the wall, providing entertainment options.
Apartment in Potrero Hill

Modern suite with private entrance near UCSF/Chase

Get-away to the top of Potrero Hill & see the sweeping views of SF city & the bay! • Clean, Modern, Private & Huge Room with bath and Separate entrance • Free, Unrestricted Street Parking on the Block . UCSF/Mission Bay/ Chase Center/Dogpatch area are 10-15 min walk . Oracle Park is 20-25 min walk • Convenient Access to the City & Beyond I-280/101, Cal train, T line, buses . Cal train is just 3-5 min away

Indoor spacesKitchenGetting around

4.87 out of 5 average rating, 167 reviews
Top guest favorite
A bright living area features large bay windows fitted with bamboo shades, allowing natural light to flood the space. A plush sectional sofa is complemented by a round glass table and artful decor, including framed artwork and decorative urns on pedestal shelves.
Apartment in Potrero Hill

Fabulous Artist Flat in the Heart of Potrero Hill

Decorated in the eclectic bohemian spirit of San Francisco, the living space is filled with original artwork, vibrant colors and souvenirs from travel. The flat, with its easy-going creative vibe, could be the place you discover inspiration for your next project. The flat is clean, comfortable and filled with eclectic artistic touches to the delight of our guests. Please no shoes worn inside.

KitchenFamilyBreakfast

4.98 out of 5 average rating, 601 reviews

Popular amenities for Mission Bay family-friendly rentals

Family-friendly home rentals with a pool