
Guesthouse vacation rentals in Mesa
Find and book unique guesthouse rentals on Airbnb
Quick stats about guesthouse rentals in Mesa

Total vacation rentals
Explore 150 vacation rentals in Mesa

Nightly prices starting at
Mesa vacation rentals start at G$8,368 GYD per night before taxes and fees

Verified guest reviews
Over 13,390 verified reviews to help you choose

Family-friendly vacation rentals
20 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 30 rentals that welcome pets

Vacation rentals with a pool
50 properties feature pools

Rentals with dedicated workspaces
80 properties have a dedicated workspace

Wi-Fi availability
150 of Mesa vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Mesa rentals

4.9 Average rating
Mesa stays are highly rated by guests—averaging 4.9 out of 5!

Nearby attractions
Mesa's top spots, include Sloan Park, Golfland Sunsplash, and Hohokam Stadium
Top-rated guesthouse rentals in Mesa
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

Spacious Casita, Quiet, Peaceful Home - No Stairs!
Cozy Casita in a beautiful, quiet neighborhood. California King bed sleeps two comfortably. 50 inch TV has cable, Netflix, DVD player with assortment of movies. Keurig coffee pot, fridge and microwave. Dining table inside. Outdoor seating opens to peaceful, scenic backyard. Parking available in the driveway. Park to the left of 2 car garage. Our Casita is a modest room that we have done our best to make comfortable for travelers who want an alternative to an impersonal hotel. No pets allowed.

Entire Suite: Private and Cozy Clark House Casita
Trade the sterile hotel vibe and feel right at home by staying at our quaint and unique historic casita. Catch up on your favorite shows in the living room with our 65 inch HD smart TV, or watch a movie while cozied up on our comfy queen size bed using the second tv in the bedroom. Our space has a kitchenette to prepare meals, and a full size bathroom. You may also relax in the shaded patio surrounded by mature trees and lush greenery. No smoking or vaping inside or outside of the property.

Cozy Casita with kitchenette
Bright, comfortable, private room with queen bed, TV, internet, A/C, bath & kitchenette (electric skillet, refrig/freezer, microwave, toaster, Cuisinart coffee maker (single cup or pot), water filter, sink). Add herbs from our courtyard to your stir-fry. Separate casita is located in a small, quiet community near freeways (101, 202). Restaurants & entertainment options nearby in Chandler or Gilbert. Drug store, grocery and fast food all within walking distance (half mile). Community pool.

Historic Firehouse Downtown Chandler king bed
Welcome to the Historic Firehouse, strategically placed a mere 5-minute stroll from the vibrant Downtown Chandler hub, overflowing with culinary delights and upscale watering holes. This restored home has been magically reimagined into a charming Airbnb sanctuary. You will be greeted by a open living and kitchen leading to 2 bedrooms, complemented by 1 remarkable bathroom. With the capacity to house up to 7 guests, this abode is the setting for an escapade with your cherished companions.

The Desert Peach | Guesthouse Near ASU + Old Town
The Desert Peach is our newly renovated Guesthouse which features a private entrance, kitchen and bathroom located in the North Tempe area. Whether you’re looking for brunch in Old Town Scottsdale, a stroll along Tempe Town Lake or a campus tour of ASU all are within 5 miles of our home! Sky Harbor Airport, Downtown Tempe, Papago Park, Phoenix Zoo and the Desert Botanical Garden are all a quick drive as well :) You’ll never be short of things to do! AZ TPT # 21445640 Tempe # STR-000083

Cozy, Private Mid-Century Casita
Enjoy your stay in the Valley of the Sun at this 350 sq. ft. stand-alone private casita with full bathroom & kitchenette. The bedroom features incredible natural light, but also the ability to block it out if you wish. Rest easy on the comfortable queen size bed and catch up on your favorite shows on the HD smart TV. WiFi is available, & for business travelers there is a laptop desk. On-site covered parking. Please no pets. This is a no-smoking property (tobacco, weed, vape).

Private, Convenient Studio Apartment
Discover the perfect blend of location and comfort in our newly renovated studio apartment. Nestled centrally between Mesa, Scottsdale, and Tempe, you're at the heart of abundant dining choices, shopping convenience, and grocery store accessibility. Just 15 minutes from Sky Harbor and a swift 30 minutes from Mesa Gateway, your travels are a breeze. Enjoy total privacy with your exclusive entrance, ensuring a tranquil, personal escape in the midst of the city's best offerings

Detached Guesthouse | Driveway Park | Full Kitchen
Enjoy our newly remodeled and professionally designed 1 bed, 1 bath private guesthouse. The stylish and cozy suite includes a full kitchen with brand new appliances, a work space, living room, and bedroom with a closet and ensuite bathroom. It is located just 15 mins away from major destinations, such as ASU, Sky Harbor International Airport, and fun attractions. We offer free parking on the property, in addition to wi-fi, Roku TV and toiletries. We would love to host you!

Casita/ Heated Pool, Hot Tub, Amazing Amenities
Private Casita with an amazing steam room and upscale shower. Heated large pool and hot tub along with three covered outbuildings: full outdoor kitchen with BBQ, full stove, MW, Hot Water Sink and large bar area; living room and dining room with wood burning fireplace. A full set of dishes, pots and pans are in this area for your use. Lots of private sitting areas or just hang out in the orchard and pick citrus fruit from the 40 plus trees.

Sanitized Spacious Desert Getaway
Newly built guest house in Northeast Mesa. Spacious Living and Kitchen area. 10 foot ceilings. Quite Neighborhood. Right around the corner from Usery Park, Hiking, biking and equestrian trails. Down the road form the Superstition Mountains. 25 minute drive to Saguaro or Canyon Lake. 15 minutes to the Salt River. Quick and easy assess to the Loop 202. Just minutes away from the Superstition Springs Mall.

Private-Detached Guesthouse & Zen Courtyard
Discover the perfect desert escape in our charming, detached casita. Tucked away in one of Chandler’s most peaceful and established neighborhoods, this private guest house offers a level of tranquility that is hard to find. Whether you are visiting for a focused business trip, a solo retreat, or a romantic weekend, you will find this space to be an intentional sanctuary designed for rest and rejuvenation.

Mesa Casita with King Bed
Casita with a king size bed and kitchenette located in a quiet Mesa neighborhood. The room is a dedicated Airbnb space in a separate building from the main house with it’s own entrance, private bath, and kitchenette perfect for a quick breakfast or a bite to eat. We are minutes from local freeways. A 15 min drive to Scottsdale, Tempe, Chandler, and Gilbert.
Popular amenities for Mesa guesthouse rentals
Family-friendly guest house rentals

Private Casita

Cozy casita in a beautiful setting

Charming & spacious Casita! Like home only better!

Private Detached Tuscan Casita!

Private and Quiet - 1 bdrm/1 bath Casita

Scottsdale Luxury Guesthouse

Our Guest House at Papago Park

Private Luxury Guesthouse in Mesa
Guest house rentals with a patio

McDowell Suite

Private Pool House & Pool in Phoenix

Ruby's Hideaway, a historic red brick studio.

Private 2BR Midtown Casita + Yard

Scottsdale Casita at Lincoln Rd

Private yard - Short walk to Mill - Historic House

Entire Private Guest House with King Master

PHX's Modern Midtown Carriage House, Free Parking
Guest house rentals with a washer and dryer

Centrally Located Renovated Guest House

Private Guest Studio in the Country

NEW Stylishly Designed Casita Steps from DTPHX

The Mesa Cottage

Gilbert Guesthouse: Centrally Located Cozy Studio

Downtown Phx | Private Guesthouse & Parking

Studio B industrial design

Guesthouse in city's most walkable neighborhood
When is the best time to visit Mesa?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$21,548 GYD | G$23,849 GYD | G$25,104 GYD | G$20,083 GYD | G$18,410 GYD | G$17,364 GYD | G$16,108 GYD | G$15,690 GYD | G$17,364 GYD | G$18,828 GYD | G$20,711 GYD | G$20,920 GYD |
| Avg. temp | 14°C | 16°C | 19°C | 23°C | 28°C | 33°C | 35°C | 35°C | 32°C | 25°C | 18°C | 13°C |
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- Phoenix Convention Center
- Chase Field
- Lake Pleasant
- TPC Scottsdale - Champions Course
- Grayhawk Golf Club
- The Westin Kierland Golf Club
- Salt River Fields at Talking Stick
- WestWorld of Scottsdale
- Sloan Park
- Desert Diamond Arena
- Peoria Sports Complex
- Surprise Stadium
- Grand Canyon University
- Tempe Beach Park
- State Farm Stadium
- Goodyear Ballpark
- Salt River Tubing
- Arizona State University
- Camelback Ranch
- Scottsdale Stadium
- Footprint Center
- We-Ko-Pa Golf Club
- Papago Park
- Hurricane Harbor Phoenix
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