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Guesthouse vacation rentals in Mesa

Find and book unique guesthouse rentals on Airbnb

Top-rated guesthouse rentals in Mesa

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Top guest favorite
A spacious California King bed is centered in the room, adorned with a white quilt. Two pillows rest against the headboard. Natural light filters through a window with blinds, illuminating the inviting sleeping area.
Guesthouse in Gilbert
4.94 out of 5 average rating, 498 reviews

Spacious Casita, Quiet, Peaceful Home - No Stairs!

Cozy Casita in a beautiful, quiet neighborhood. California King bed sleeps two comfortably. 50 inch TV has cable, Netflix, DVD player with assortment of movies. Keurig coffee pot, fridge and microwave. Dining table inside. Outdoor seating opens to peaceful, scenic backyard. Parking available in the driveway. Park to the left of 2 car garage. Our Casita is a modest room that we have done our best to make comfortable for travelers who want an alternative to an impersonal hotel. No pets allowed.

Top guest favorite
Guesthouse in Mesa
4.97 out of 5 average rating, 204 reviews

Entire Suite: Private and Cozy Clark House Casita

Trade the sterile hotel vibe and feel right at home by staying at our quaint and unique historic casita. Catch up on your favorite shows in the living room with our 65 inch HD smart TV, or watch a movie while cozied up on our comfy queen size bed using the second tv in the bedroom. Our space has a kitchenette to prepare meals, and a full size bathroom. You may also relax in the shaded patio surrounded by mature trees and lush greenery. No smoking or vaping inside or outside of the property.

Top guest favorite
A private room features a spacious bed with layered bedding, complemented by two decorative pillows. A small dining table with two chairs sits in the corner. Large windows with wooden shutters frame a view of greenery outside, and landscape artwork adorns the wall.
Guesthouse in Chandler
4.98 out of 5 average rating, 125 reviews

Cozy Casita with kitchenette

Bright, comfortable, private room with queen bed, TV, internet, A/C, bath & kitchenette (electric skillet, refrig/freezer, microwave, toaster, Cuisinart coffee maker (single cup or pot), water filter, sink). Add herbs from our courtyard to your stir-fry. Separate casita is located in a small, quiet community near freeways (101, 202). Restaurants & entertainment options nearby in Chandler or Gilbert. Drug store, grocery and fast food all within walking distance (half mile). Community pool.

Top guest favorite
An open living area features high ceilings with exposed beams and industrial-style ceiling fans. Large glass doors provide ample natural light and a view of the outdoor patio. A cozy couch with decorative pillows is positioned near a rustic kitchen with wooden cabinets and modern appliances.
Guesthouse in Chandler
4.89 out of 5 average rating, 136 reviews

Historic Firehouse Downtown Chandler king bed

Welcome to the Historic Firehouse, strategically placed a mere 5-minute stroll from the vibrant Downtown Chandler hub, overflowing with culinary delights and upscale watering holes. This restored home has been magically reimagined into a charming Airbnb sanctuary. You will be greeted by a open living and kitchen leading to 2 bedrooms, complemented by 1 remarkable bathroom. With the capacity to house up to 7 guests, this abode is the setting for an escapade with your cherished companions.

Top guest favorite
The sleeping area features a queen size bed with a soft pink coverlet, complemented by beige and gray decorative pillows. A cozy sofa is situated next to the bed, and large windows allow natural light to brighten the space. A stylish rug anchors the room.
Guesthouse in Tempe
5 out of 5 average rating, 162 reviews

The Desert Peach | Guesthouse Near ASU + Old Town

The Desert Peach is our newly renovated Guesthouse which features a private entrance, kitchen and bathroom located in the North Tempe area. Whether you’re looking for brunch in Old Town Scottsdale, a stroll along Tempe Town Lake or a campus tour of ASU all are within 5 miles of our home! Sky Harbor Airport, Downtown Tempe, Papago Park, Phoenix Zoo and the Desert Botanical Garden are all a quick drive as well :) You’ll never be short of things to do! AZ TPT # 21445640 Tempe # STR-000083

Top guest favorite
A bright and airy studio space features a comfortable bed with crisp white bedding and a cozy sitting area with a plush sofa. Natural light fills the room through the window, and a small bedside table with a lamp adds a touch of warmth.
Guesthouse in Mesa
4.98 out of 5 average rating, 301 reviews

Private, Convenient Studio Apartment

Discover the perfect blend of location and comfort in our newly renovated studio apartment. Nestled centrally between Mesa, Scottsdale, and Tempe, you're at the heart of abundant dining choices, shopping convenience, and grocery store accessibility. Just 15 minutes from Sky Harbor and a swift 30 minutes from Mesa Gateway, your travels are a breeze. Enjoy total privacy with your exclusive entrance, ensuring a tranquil, personal escape in the midst of the city's best offerings.

Guest favorite
A spacious bedroom is highlighted by natural light from a door leading outside. The room features a queen size bed covered with a blue striped comforter, flanked by two bedside tables with lamps. Framed artwork adorns the walls, adding character to the space.
Guesthouse in Mesa
4.94 out of 5 average rating, 312 reviews

Cozy, Private Mid-Century Casita

Enjoy your stay in the Valley of the Sun at this 350 sq. ft. stand-alone private casita with full bathroom & kitchenette. The bedroom features incredible natural light, but also the ability to block it out if you wish. Rest easy on the comfortable queen size bed and catch up on your favorite shows on the HD smart TV. WiFi is available, & for business travelers there is a laptop desk. On-site covered parking. Please no pets. This is a no-smoking property (tobacco, weed, vape).

Superhost
A bright living area is presented with a comfortable sectional sofa and accent chairs in various shades of grey and teal. A television is positioned on a stylish media console, while a decorative area rug adds color beneath a coffee table. Natural light filters through the window.
Guesthouse in East Mesa
4.93 out of 5 average rating, 198 reviews

Detached Guesthouse | Driveway Park | Full Kitchen

Enjoy our newly remodeled and professionally designed 1 bed, 1 bath private guesthouse. The stylish and cozy suite includes a full kitchen with brand new appliances, a work space, living room, and bedroom with a closet and ensuite bathroom. It is located just 15 mins away from major destinations, such as ASU, Sky Harbor International Airport, and fun attractions. We offer free parking on the property, in addition to wi-fi, Roku TV and toiletries. We would love to host you!

Top guest favorite
Guesthouse in East Mesa
4.89 out of 5 average rating, 358 reviews

Casita/ Heated Pool, Hot Tub, Amazing Amenities

Private Casita with an amazing steam room and upscale shower. Heated large pool and hot tub along with three covered outbuildings: full outdoor kitchen with BBQ, full stove, MW, Hot Water Sink and large bar area; living room and dining room with wood burning fireplace. A full set of dishes, pots and pans are in this area for your use. Lots of private sitting areas or just hang out in the orchard and pick citrus fruit from the 40 plus trees.

Guest favorite
The spacious living and kitchen area features wooden cabinetry and modern appliances. A comfortable striped sofa faces a television on a stand. A dining table with chairs is set near a window, which allows natural light to fill the room.
Guesthouse in Mesa
4.95 out of 5 average rating, 304 reviews

Sanitized Spacious Desert Getaway

Newly built guest house in Northeast Mesa. Spacious Living and Kitchen area. 10 foot ceilings. Quite Neighborhood. Right around the corner from Usery Park, Hiking, biking and equestrian trails. Down the road form the Superstition Mountains. 25 minute drive to Saguaro or Canyon Lake. 15 minutes to the Salt River. Quick and easy assess to the Loop 202. Just minutes away from the Superstition Springs Mall.

Top guest favorite
A bright and airy living space features a comfortable light-colored couch adorned with decorative pillows and a soft throw. A glass dining table for two is set beside a window with elegant window treatments, while wall art and decor add a touch of personality.
Guesthouse in Chandler
4.98 out of 5 average rating, 407 reviews

Private-Detached Guesthouse & Zen Courtyard

Discover the perfect desert escape in our charming, detached casita. Tucked away in one of Chandler’s most peaceful and established neighborhoods, this private guest house offers a level of tranquility that is hard to find. Whether you are visiting for a focused business trip, a solo retreat, or a romantic weekend, you will find this space to be an intentional sanctuary designed for rest and rejuvenation.

Guest favorite
A well-lit bedroom features a king size bed adorned with a floral blue and white duvet. Natural light streams in through plantation shutters. A minimalist armchair and lamp complement the space, while a simple rug adds warmth underfoot.
Guesthouse in East Mesa
4.96 out of 5 average rating, 573 reviews

Mesa Casita with King Bed

Casita with a king size bed and kitchenette located in a quiet Mesa neighborhood. The room is a dedicated Airbnb space in a separate building from the main house with it’s own entrance, private bath, and kitchenette perfect for a quick breakfast or a bite to eat. We are minutes from local freeways. A 15 min drive to Scottsdale, Tempe, Chandler, and Gilbert.

Popular amenities for Mesa guesthouse rentals

When is the best time to visit Mesa?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceG$21,548 GYDG$23,849 GYDG$25,104 GYDG$20,083 GYDG$18,410 GYDG$17,364 GYDG$16,108 GYDG$15,690 GYDG$17,364 GYDG$18,828 GYDG$20,711 GYDG$20,920 GYD
Avg. temp14°C16°C19°C23°C28°C33°C35°C35°C32°C25°C18°C13°C

Quick stats about guesthouse rentals in Mesa

  • Total vacation rentals

    Explore 150 vacation rentals in Mesa

  • Nightly prices starting at

    Mesa vacation rentals start at G$8,368 GYD per night before taxes and fees

  • Verified guest reviews

    Over 13,390 verified reviews to help you choose

  • Family-friendly vacation rentals

    20 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 30 rentals that welcome pets

  • Vacation rentals with a pool

    50 properties feature pools

  • Rentals with dedicated workspaces

    80 properties have a dedicated workspace

  • Wi-Fi availability

    150 of Mesa vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Mesa rentals

  • 4.9 Average rating

    Mesa stays are highly rated by guests—averaging 4.9 out of 5!

  • Nearby attractions

    Mesa's top spots, include Sloan Park, Golfland Sunsplash, and Hohokam Stadium

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