
Guesthouse vacation rentals in Mesa
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in Mesa
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

Resort-living in private Studio @ Villa Paradiso
* Private, bright guesthouse immersed in a peaceful oasis of lush landscaping. The guesthouse is right in front of our swimming pool. * Fully remodeled: Kitchen, TV, Wifi, Nespresso & more. * Central location: 10 mins from Old Town Scottsdale, ASU, Sky Harbor Airport, Spring Training & more. Check out my profile for two Luxury B&B suite listings in the main house. Private bedroom & bath, full access to living areas + breakfast. Ask about photoshoots or events across the various property areas.

Entire Private Guest House with King Master
•Location, Location, Location! Extremely safe/social neighborhood just minutes from Oldtown! 5- minute drive by car and 10 minutes by E-scooters! •Bordered by lush greenery, your private backyard/covered patio is a perfect place to enjoy the outdoors •Recently built in 2022 with luxury, comfort, and entertainment in mind ~ you'll love the vibe of your private small backyard and small yet spacious 520sqft space. This guest house has its own private, yet beautiful entrance TPT 21476951 AZ 2026023

Walk to ASU | Downtown Retreat + Private Yard
Welcome to The Studio at Maple Ash - your private hideaway—perfect for ASU parents, visiting professors, business travelers, couples, and solo travelers. Located in the heart of downtown Tempe, inside the iconic Maple Ash neighborhood, just 10 minutes from Sky Harbor Airport. Walk to ASU, Gammage Auditorium, and Tempe Beach Park in minutes. Whether you're visiting your ASU student, catching a music festival, Spring Training game, or attending a Broadway show, this is the perfect home base.

Cozy Casita with kitchenette
Bright, comfortable, private room with queen bed, TV, internet, A/C, bath & kitchenette (electric skillet, refrig/freezer, microwave, toaster, Cuisinart coffee maker (single cup or pot), water filter, sink). Add herbs from our courtyard to your stir-fry. Separate casita is located in a small, quiet community near freeways (101, 202). Restaurants & entertainment options nearby in Chandler or Gilbert. Drug store, grocery and fast food all within walking distance (half mile). Community pool.

Luxury Modern Executive Retreat
Northeast Mesa location close to Tonto National Forest, the Salt River and Saguaro lake. 5 minutes from Boeing, Nammo Talley or MD Helicopter. 25 minutes from downtown Phoenix or Scottsdale. Nestled at the base of the Goldfield mountains. Contemporary open floor plan with modern design. Private entrance and single parking spot in front of the main house. Fast WiFi. Roku and cable TV. Beautiful, quiet neighborhood close to city amenities as well as biking and hiking trails. TPT# 21558238

Private, Convenient Studio Apartment
Discover the perfect blend of location and comfort in our newly renovated studio apartment. Nestled centrally between Mesa, Scottsdale, and Tempe, you're at the heart of abundant dining choices, shopping convenience, and grocery store accessibility. Just 15 minutes from Sky Harbor and a swift 30 minutes from Mesa Gateway, your travels are a breeze. Enjoy total privacy with your exclusive entrance, ensuring a tranquil, personal escape in the midst of the city's best offerings.

Casita/ Heated Pool, Hot Tub, Amazing Amenities
Private Casita with an amazing steam room and upscale shower. Heated large pool and hot tub along with three covered outbuildings: full outdoor kitchen with BBQ, full stove, MW, Hot Water Sink and large bar area; living room and dining room with wood burning fireplace. A full set of dishes, pots and pans are in this area for your use. Lots of private sitting areas or just hang out in the orchard and pick citrus fruit from the 40 plus trees.

Private Luxury Guesthouse in Mesa
Relax in this calm, stylish space. This guesthouse is the perfect getaway for couples or solo travelers. + King Bed + Sofa Bed + Firepit + Nespresso Machine + 2 Burner Cooktop + Cocktail Shaker Set + Full-Length Mirror + Comfy Robes + Rain Shower Head + Water Softener + Dedicated Parking + Private Entrance 8 min ➡ Downtown Mesa 10 min ➡ Downtown Gilbert 20 min ➡ Sky Harbor Airport 30 min ➡ Central Phoenix @glade.guesthouse

Cozy, Private Mid-Century Casita
Enjoy your stay in the Valley of the Sun at this 350 sq. ft. stand-alone private casita with full bathroom & kitchenette. The bedroom features incredible natural light, but also the ability to block it out if you wish. Rest easy on the comfortable queen size bed and catch up on your favorite shows on the HD smart TV. WiFi is available, & for business travelers there is a laptop desk. Please, no children or animals.

Mesa Casita with King Bed
Casita with a king size bed and kitchenette located in a quiet Mesa neighborhood. The room is a dedicated Airbnb space in a separate building from the main house with it’s own entrance, private bath, and kitchenette perfect for a quick breakfast or a bite to eat. We are minutes from local freeways. A 15 min drive to Scottsdale, Tempe, Chandler, and Gilbert.

The White Barn @ Freedom Farms
Kick off your boots and relax in this calm, stylish, private guest house on Freedom Farms! Explore the natural swimming pond on the property, venture out to the Sonoran desert for a nature hike, tube down the salt river or mountain bike in Usery! You'll find our location close to the city but not in the city.

La Cabra Casita: Poolside Oasis on Urban Farm
Enjoy an experience unlike any other at our mini ranch in the heart of Chandler. After a day of sunshine in the beautiful Sonoran desert, retreat to your private La Cabra Casita. Relax by the pool, grill up some dinner, feed the goats and alpacas, and in the morning enjoy some fresh duck and chicken eggs.
Popular amenities for Mesa guesthouse rentals
Family-friendly guest house rentals

Mid Century Modern Guest House Historic District

Best Little Guesthouse in Melrose !

Detached, Private, Clean & Safe Guesthouse with Large Patio

Private Casita

Urban Green House The Garden House

Sanitized Spacious Desert Getaway

Queen Creek Getaway | Steps to Target & Dining!

Cozy Casita Getaway - King Bed - Pool
Guest house rentals with a patio

Sunshine Studio! Phx/Scottsdale border!

Ruby's Hideaway, a historic red brick studio.

Private yard - Short walk to Mill - Historic House

Spacious Midtown guesthouse with full privacy

Downtown Studio - Woodland Historic District

Lux DTPHX 1-Bed Casita w/Private Patio and Laundry

Paradise Valley Casita Near Old Town Scottsdale Az

Amazing Casita with Minigolf & Corn-Hole
Guest house rentals with a washer and dryer

The Casita in Tempe Arizona

Charming Redbrick Cottage

Gilbert Guesthouse: Centrally Located Cozy Studio

Private studio! Central to popular locations.

Downtown Phx | Private Guesthouse & Parking

Studio B industrial design

Private and Quiet - 1 bdrm/1 bath Casita

Enchanting Ahwatukee Secret Casita
When is the best time to visit Mesa?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$21,095 GYD | G$23,810 GYD | G$24,854 GYD | G$20,050 GYD | G$18,380 GYD | G$17,335 GYD | G$17,335 GYD | G$16,082 GYD | G$17,126 GYD | G$19,633 GYD | G$20,259 GYD | G$19,842 GYD |
| Avg. temp | 14°C | 16°C | 19°C | 23°C | 28°C | 33°C | 35°C | 35°C | 32°C | 25°C | 18°C | 13°C |
Quick stats about guesthouse rentals in Mesa

Total vacation rentals
Explore 150 vacation rentals in Mesa

Nightly prices starting at
Mesa vacation rentals start at G$6,266 GYD per night before taxes and fees

Verified guest reviews
Over 12,060 verified reviews to help you choose

Family-friendly vacation rentals
20 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 30 rentals that welcome pets

Vacation rentals with a pool
40 properties feature pools

Rentals with dedicated workspaces
70 properties have a dedicated workspace

Wi-Fi availability
150 of Mesa vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Mesa rentals

4.9 Average rating
Mesa stays are highly rated by guests—averaging 4.9 out of 5!

Nearby attractions
Mesa's top spots, include Sloan Park, Golfland Sunsplash, and Hohokam Stadium
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- Lake Pleasant Regional Park
- Chase Field
- Phoenix Convention Center
- Grand Canyon University Championship Golf Course
- TPC Scottsdale - Champions Course
- Salt River Fields at Talking Stick
- Arizona Grand Golf Course
- The Westin Kierland Golf Club
- Salt River Tubing
- WestWorld of Scottsdale
- Grayhawk Golf Club
- Hurricane Harbor Phoenix
- Tempe Beach Park
- Peoria Sports Complex
- Sloan Park
- Dobson Ranch Golf Course
- Ocotillo Golf Club
- Lost Dutchman State Park
- We-Ko-Pa Golf Club
- Seville Golf & Country Club
- Red Mountain Ranch Country Club
- Oasis Water Park
- Trilogy Golf Club at Power Ranch
- Gainey Ranch Golf Club
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