
House vacation rentals in Los Santos
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Top-rated house rentals in Los Santos
Guests agree: these houses are highly rated for location, cleanliness, and more.

NinaHouse, spacious and cool house in Chitré.
House just for you, now with a water tank! Up to 7 people, spacious and in one of the best areas of Chitré, quiet and family-friendly, access to the pool in the social area, parks and courts, close to everything: supermarkets, casino, bus; come to Chitre and enjoy typical meals, crafts; plan your walks and visit the best beaches: Pedasi, Venao, Isla Iguana, you can work from NinaHouse with fast internet. We now have air conditioning in the living room for your comfort.

Country House Like in the City / La Casita
Casa fresca, con árboles, naturaleza y portales p/ descansar, cámaras de seguridad afuera Ubicación céntrica, cerca de malls, restaurantes, buses y ciclovía. Entrada privada, estacionamientos, cocina completa, mobiliario completo, baño, TV HD con cable, AC en recámara, agua caliente y Wi-Fi. ENG, PORT, FRAN and ITA Spoken! Contamos con un pozo de agua y sistema de purificación de agua por ósmosis inversa: agua segura, potable y purificada!

Casa Blu Central Chitre| Sleeps 6| Private Parking
Stay in a newly renovated private home in the center of Chitré with free gated parking, a large backyard, fast Wi-Fi, and space for the whole family. Walk to restaurants, supermarkets and the cathedral while enjoying the comfort of an entire home to yourselves. It combines comfort, spaciousness, and natural light in every corner — perfect for families or groups of friends looking for a place that feels just like home.

Chitré Oasis: Modern Home with Private Pool & BBQ
Welcome to your private oasis in Chitré 🌴 Soak up the Azuero sun in our stunning pool 🏊♂️ and unwind on the covered terrace with a BBQ area 🍖, perfect for grilling and outdoor dining. The house is strategically located in a very safe residential area, just minutes away from Mall Paseo Central, Riba Smith supermarket, and the vibrant downtown Chitré 🛍️. Featuring modern spaces and full A/C.

Alquilo Hermosa Casa en Chitré Centro
Casa espaciosa y equipada en zona céntrica de Chitré. 3 recámaras con A/C, 2.5 baños, Cocina completa, Wifi rápido, Balcones y parking techado. Ideal para familias, grupos o viajes de trabajo. Spacious house, Fully equipped home in central Chitré. 3 A/C bedrooms, 2.5 baths, full kitchen, Fast wifi, Balconies and covered parking. Perfect for families, groups or business trips.

Our Happy Place
Relax with the whole family in this quiet place to stay. It is a single-family residence, in the master bedroom we have a Queen bed (1.50 m x 1.90 m) in the second bedroom we have 2 Twin beds (90 m x 1.90 m). The residence can comfortably accommodate 4 people, however we have a sofa bed and a Pee bed available for 2 additional people. Check the small extra cost for additional people.

Minimalist House In Chitre
THIS STYLISH PLACE TO STAY IS PERFECT. CENTRAL CHITRE: THE HOUSE IS IN A DEAD END, SUPER SAFE AND QUIET NEIGHBORHOOD ONLY 2 BLOCKS FROM MARKET SUPER CARNES FEATURES: 2 BEDROOMS WITH A/C ONE BATHROOM: KITCHEN, LIVING ROOM, TERRACE, PARKING FOR 4 CARS. WASHING MACHINE AND DRYER MACHINE, HOT WATER, WATER RESERVE TANK 2600 LITER, CENTRAL ALARM SYSTEM ENTIRE HOUSE

6 Bedroom 6 bathrooms up to 16 guests
Experience the charm of the Panamanian countryside with modern comfort. Our cozy home in La Villa de Los Santos offers the perfect mix of tradition, relaxation, and convenience. Ideally located within walking distance of the town center, just 250m from Parque Simón Bolívar and 50m from Parque Rufina Alfaro. Perfect for families or a relaxing getaway.

Family home for 8 | 3 bedrooms with A/C
Entire house for up to 8 guests in Los Santos. Just minutes from the Feria de Azuero. Enjoy 3 air-conditioned bedrooms, bathrooms, high-speed Wi-Fi, an equipped kitchen, and private parking. Great for families, groups and travelers seeking comfort and an excellent location.

Spacious house in Villa de los Santos
Comfortable family accommodation in La Villa de Los Santos, with Wi-Fi, A/C, equipped kitchen, patio and parking. Located near supermarkets and plazas. Only 15 minutes from El Rompió and Monagre, 45 minutes from Isla Iguana and 1h 30 minutes from Playa Venao.

Luxury Villa
Luxuriously furnished villa, with a pool right outside the door. A magical place to spend time with family, partner or friends. 2 bedrooms, 1 bathroom, furnished, shared parking. The perfect place to rest, definitely the best villa in the condo.

Cozy country-style house.
Enjoy the simplicity of this quiet and centrally-located accommodation, a 5-minute walk from Union Park, and 2 minutes from restaurants and supermarkets.
Popular amenities for Los Santos house rentals
House rentals with a pool

Accommodation in Chitré, close to everything

Brisas de los Guayacanes, house 253

Exclusive Villa

Casa en Residencial Brisas de los Guayacanes

Chitré Pool & BBQ House | Sunny Patio & AC
Weekly house rentals

Elegance and comfort in one place

El Refugio: Nature Escape in Chitré

Two-story house.

New house in Chitré located in a very central place

Casa Centenario

Villa Aguamarina - Entre mar y tradición

Las Palmas Village

Enjoy your next stay in Chitré!
Private house rentals

The ideal escape for comfort and tranquility.

The Golden Mansion

Entire House in La Villa de Los Santos

Rent house in the Arena de Chitre, available.

Rented for the fair in Villa de los Santos

The sand

Cozy House in Chitre, Monagrillo

Casita de Chitre





