House vacation rentals in Lake City

4.95 out of 5 average rating, 159 reviews

Riverfront Retreat (Ichetucknee) w/ Kayaks & Tubes

DIRECTLY ON the crystal clear waters of the Ichetucknee River, the Riverfront Retreat is a beautiful rustic home and the perfect place to find peace, rest & relaxation. Swim or go tubing on what US Travel News deemed as Florida's best tubing river. Private viewing platform with floating dock right on the water. 4 Bedrooms & sleeps 9 with ping pong & foosball and is perfect for almost any group. We offer tubes & kayaks for guests to use during their stay. After 5 guests, $25 per person, per day.

The lodge features a two-level design with a spacious upstairs screened porch illuminated by warm lights. A staircase connects to the lower level, where additional seating is visible, surrounded by lush greenery, creating a comfortable outdoor space.

4.99 out of 5 average rating, 182 reviews

The Suwannee River Rest & Adventures

Nestled in Branford, FL, along the scenic Suwannee River in Hatch Bend, this pet friendly, three-bedroom, three-bath lodge is perfect for weekends or extended stays. Upstairs features two king bedrooms with ensuite baths, a cozy living area with a gas fireplace, and a fully equipped modern kitchen. Downstairs offers a king bedroom, full bath, kitchenette, and living space. An enclosed elevator makes transporting gear easy. Experience comfort, charm, and Suwannee River beauty at our retreat!

4.87 out of 5 average rating, 171 reviews

A serene scene of a cypress log home surrounded by lush greenery is reflected in the calm waters of the Santa Fe River. A wooden dock is visible at the water's edge, inviting relaxation amid nature.

Home in High Springs

Family Treehouse on The Santa Fe River

Our front yard is the Santa Fe River. Come enjoy a nature retreat in this cypress log home! Right by Tree House spring and nestled between two state parks, but less than five minutes to downtown. Whether you are looking for rest and relaxation or recreation, our home offers both. Take in the scenery and catch your dinner from the riverbank. Recline in the sunshine on our dock (12’ x 12’). Keep an eye out for otters! It is a two hour float downriver to Poe Springs, Rum Island, and Blue Springs.

4.95 out of 5 average rating, 215 reviews

A spacious kitchen showcases modern white cabinetry and a large island with seating for four. Stylish pendant lights hang above the island, and stainless steel appliances are integrated into the design. A cozy living area is visible in the background, providing a seamless flow to the space.

Home in Jennings

Gated 5 acres with fitness, 5 tvs, king bed

There's plenty of boat and trailer parking on gated property. 3 types of coffee makers. Keurig ( with pods), French press, Drip. Quiet, secluded, New custom home on 5+ acres. 6-7 min off I75 Kick back and relax in this calm, stylish space. Peaceful Country Living meets Luxury and Style. Nearby Fun: 1. Jennings GP- Motor Track 2. Spirit of the Suwanee 3. Madison State Blue Park -Madison River 4 Wild Adventures - 30 Min 6. Cross Roads Metroplex 7. The Florida HikingTrail and much more...

A round treehouse structure is nestled among lush greenery. The building is elevated on stilts, featuring a spacious porch with white railings. A paved path leads to the entrance, surrounded by trees and foliage that create a natural, serene setting.

4.96 out of 5 average rating, 239 reviews

Otter Landing on Santa Fe River, 13 private acres

Spend all the time you want at home in Nature relaxing or recreating. This unique treehouse home is set high up in the trees and on 13 acres of natural habitat on the banks of the Santa Fe River. The Santa Fe has so much wildlife, and we are near the famous crystalline Ichetucknee River and miles of public trails. We share our kayaks, a canoe, and many amenities for your stay. So go for a solo paddle, join local guide trips to various springs, or hike on the property and at nearby parks.

A blue two-story house is reflected in the calm waters of a pond. Surrounded by tall trees, the house features a covered porch and large windows. Nearby, a small outbuilding enhances the outdoor space, creating a serene and inviting view.

4.97 out of 5 average rating, 239 reviews

The Blue House

This quaint, cozy getaway is exactly what you need to wind down and relax while creating a modern cabin feel. After a long day sit down and enjoy a massage from our very own massage chair. With free Wi-Fi Internet and access to live streaming to enjoy your favorite channels and shows. Along with a full functioning kitchen you’ll also be able to play board games in the rec room, or try your hand on the four player arcade loaded with 3000 games to choose from! Come RELAX at “The Blue House”.

A comfortable living area features a light-colored sofa positioned adjacent to an accent chair. A wooden entertainment center holds a television, while a patterned area rug anchors the space. Natural light is provided by a nearby window, enhancing the inviting atmosphere.

4.84 out of 5 average rating, 131 reviews

Deerwood Cottage 3BR /2BA Brick Home

Peaceful 3 BR 2 BA This is your adventure headquarters! Bring the whole family, or just get away to this great place with lots of space! This house is located on an acre in a nice rural neighborhood within 1.5 miles of a great park with hiking trails, biking trails, great fishing, birdwatching, disc golf and beautiful wildlife! Within a short drive are unique to North Florida features which include the following: crystal clear springs; a national forest ; racing venues; breweries & more

4.92 out of 5 average rating, 106 reviews

A modern farmhouse features a welcoming façade with multiple windows and a red front door. Neat landscaping with low shrubs lines the entrance, and a basketball hoop is seen at the side of the driveway. The home is surrounded by a spacious green lawn.

Home in Lake Butler

6+ Sleeper Farm Escape with Huge Yard & RV Hookup

This modern farmhouse, built on a working family farm, is minutes from watersports and nature trails, a 20 minute drive to nearby Springs and the crystal clear Ichetucknee River, and only 30 minutes from the University of Florida and Lake City. We are closely located to many local wedding venues: (ses list below) Pine Grove Barns 5.3 miles C Bar Ranch 10.5 miles Valley View 11.6 miles Belle Oaks Barn 13.8 miles The Barn at Rembert Farms 16.3 mile The Iron Vine 26 miles

A welcoming front porch features a wooden staircase leading to the entrance. A colorful sign displays a friendly message. Green shrubs border the pathway, while the porch offers shaded seating for relaxation. The exterior showcases a combination of stone and wood accents.

5.0 out of 5 average rating, 102 reviews

The Restored Haven

Come inside & rest your soul! This newly renovated home has plenty of room for families to enjoy time together. It's minutes from the Suwannee River, state parks & natural springs. Live Oak is a family-friendly community with playgrounds, walking paths & even a disc golf course. Our home has a full kitchen, but there are plenty of restaurants nearby. We have books & games for spending time inside, and plenty of recommendations for nearby fun. We hope you'll visit us soon!

Sunlight streams through the trees of a tranquil forest, creating a warm glow amidst the natural setting. Leafy branches arch overhead, while the ground is covered in a carpet of leaves, inviting moments of peaceful reflection and connection with nature.

4.91 out of 5 average rating, 139 reviews

Waldhaus! Forest sanctuary close to springs!

House nestled in the middle of the forest. Peaceful retreat with 2 decks. Fire pit and grill with gazebo. You are 5 min to I 75 , 5 min to Oleno park and 10 min to itchetucknee river. Ginnie springs is 25 min. High speed internet w Roku . Around the property you see at any given day deer turkey & cows. Star gazing . The house is very cozy , well equipped , roomy. Baby travel bed/pen and table seat . Corn hole game. Great fun for family !

A well-lit wooden boardwalk extends toward the lake, flanked by trees. The scene is set during twilight, with a soft glow illuminating the path. The reflection of the evening sky and trees on the calm water enhances the tranquil ambiance of the location.

4.96 out of 5 average rating, 397 reviews

Papa Joe’s Lake House

Quiet little piece of heaven on earth. Enjoy the lake views, sit by a fire, enjoy the nature God has provided in our sanctuary on Pickett Lake. Use the grill or take a short drive to Branford or Mayo and enjoy some of the restaurants. Outdoor fire pit includes wood. PLEASE NOTE- Lake levels are EXTREMELY LOW. There is currently no water at the dock for fishing or swimming. We are currently experiencing extreme drought conditions.

4.95 out of 5 average rating, 409 reviews

The single-story home is surrounded by lush green grass and trees, featuring two sets of windows flanked by dark green shutters. A small porch with a seating area sits in front, complemented by flowering bushes. The sky is bright with scattered clouds.

Home in Mayo

Small Town Charm & Living

Water Lover’s Paradise! Great place to get away for spring hopping, kayaking, canoeing, cave diving, or just a little R & R. If crystal clear springs are what you’re looking for, we’re just minutes from Lafayette Blue Springs State Park, Troy Springs State Park, Wes Skiles Peacock Springs State Park, & the Ichetucknee Springs State Park. We’re just 35 minutes from the Gulf of Mexico and fresh seafood restaurants.

Popular amenities for Lake City house rentals

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

House rentals with a pool

The living area features a spacious white-sectional sofa adorned with neutral-toned throw pillows and soft blankets. A rustic coffee table sits in the center, flanked by decorative floral arrangements. Large windows allow natural light to illuminate the space, while a serene outdoor view is visible.

4.91 out of 5 average rating, 176 reviews

Modern Muse w/Firepit, Salt Pool and Cabanas

A spacious backyard features a rectangular swimming pool, bordered by a gray patio. Lounge chairs sit nearby, inviting relaxation. Tall trees and lush greenery surround the area, providing a natural setting, while a wooden fence offers privacy.

4.94 out of 5 average rating, 124 reviews

Modern 3BR Pool Home | Near UF, Downtown & Dining

4.82 out of 5 average rating, 254 reviews

A serene outdoor space features a wooden deck with four Adirondack chairs arranged around a central fire pit. Soft lighting is provided by hanging string lights, enhancing the ambiance. Surrounding trees provide shade and a sense of privacy in the green, grassy area.

Home in Alachua

Gated Golf Getaway close to Springs and UF

A stylish living room is illuminated by natural light through large windows. A plush sectional sofa and a comfortable armchair are arranged around a low coffee table, featuring a decorative centerpiece. A contemporary chandelier hangs overhead, providing additional ambient light.

4.97 out of 5 average rating, 130 reviews

Rare & Spacious Family Oasis • Private Pool &Games

4.89 out of 5 average rating, 110 reviews

A charming bungalow is surrounded by well-kept grassy areas and lush shrubs. A fountain stands at the center of the front yard, enhancing the serene setting. The inviting porch features decorative plants, and the structure boasts a fresh white exterior with a dark roof under a clear blue sky.

Home in Alachua

The Boujee Bungalow ~with Soak Tub & Private Yard!

Superhost

A spacious bedroom features a blue accent wall, a large window providing natural light, and views of the surrounding greenery. A sleek desk and chair are positioned beside a stylish wardrobe. A decorative area rug complements the room's calming color palette.

4.83 out of 5 average rating, 111 reviews

Luxury, newly built modern & spacious house

A two-story white house features a classic design with black shutters and a covered front entrance. The wide pathway leads to the main door, surrounded by neatly landscaped greenery. Large windows allow natural light to flow into the home, enhancing its welcoming appearance.

4.89 out of 5 average rating, 132 reviews

Coaches House - 1.5 mile from Ben Griffin Stadium

5.0 out of 5 average rating, 20 reviews

Graff Place

Weekly house rentals

4.95 out of 5 average rating, 204 reviews

Home in Fort White

Pope's Camp House

4.89 out of 5 average rating, 152 reviews

Home in O'Brien

The Hidden Palms

A two-story house with a green roof features a welcoming front porch adorned with several chairs. Lush greenery surrounds the exterior, and large windows reflect natural light. The open yard adds to the spacious feel of the property, inviting outdoor relaxation.

4.85 out of 5 average rating, 155 reviews

Jonny and Fafu house

4.87 out of 5 average rating, 246 reviews

Home in Fort White

Bowman’s Landing Spring House Santa Fe Riverfront

5.0 out of 5 average rating, 227 reviews

An outdoor seating area is arranged around a square fire pit table, surrounded by four dark wicker chairs. The space features a chevron-patterned outdoor rug and offers views of the lake, which reflects the soft colors of dawn. Kayaks and a buoy are visible nearby.

Home in Lake Park

Lakefront guesthouse by I-75 and the FL/GA line

4.96 out of 5 average rating, 71 reviews

~ La Casita ~ about 6 minutes to I-75

A single-story home features a wide driveway leading to a two-car garage. The exterior is complemented by a large green tree providing shade, along with a neatly landscaped yard. A clear blue sky with scattered clouds is visible in the background.

4.96 out of 5 average rating, 50 reviews

Home away from Home

A spacious bedroom features a plush bed with a white comforter, accentuated by decorative pillows. Two bedside tables with matching lamps stand beside the bed. A large piece of wall art depicting blue waves hangs above the headboard, while natural light enters through a nearby window.

4.87 out of 5 average rating, 97 reviews

Lake City Luxury New listing whole house

Private house rentals

A black metal gate is prominently displayed, featuring a deer silhouette and the name 'DuBose' in white lettering. The gate is set against a backdrop of green trees, creating a serene entrance to the property. A gravel pathway is visible leading through the gate.

5.0 out of 5 average rating, 65 reviews

Welcome to peaceful paradise!

4.97 out of 5 average rating, 34 reviews

Home in White Springs

Luxury Riverside Escape on the Suwannee

A well-furnished living room features a combination of comfortable seating including an armchair and a sofa. A decorative wooden coffee table holds small plants, and the fireplace, adorned with greenery, adds character to the space. A wall-mounted television is visible above the fireplace.

4.9 out of 5 average rating, 96 reviews

Kimberley's Casita - Cozy, Charming, Convenient

4.82 out of 5 average rating, 28 reviews

Allen & Evelyn Country Comfort

A vibrant living area features plush green sofas and yellow accent chairs, arranged around a coffee table. A red accent wall enhances the space, while a flat-screen TV is mounted for entertainment. Light streams in through window treatments, creating an inviting atmosphere.

4.9 out of 5 average rating, 67 reviews

The Velvet Rose

5.0 out of 5 average rating, 14 reviews

Home in Wellborn

New Construction 3-BR Farmhouse in Wellborn, FL

5.0 out of 5 average rating, 69 reviews

A comfortable living area features a mix of seating options, including a dark brown sofa and woven armchairs. A decorative area rug complements the space, while sunlight filters through window treatments. Artwork is displayed on the wall, and a small table holds a lamp.

Home in White Springs

Hillside Abode in Historic White Springs

Superhost