Guesthouse vacation rentals in Knoxville

4.98 out of 5 average rating, 412 reviews

A cozy sleeping area features a spacious bed adorned with a lace coverlet. A comfortable sofa and armchair offer seating under the warm glow of two lamps, while a decorative rug adds texture to the wooden floor. Artwork decorates the walls, enhancing the room's charm.

Guesthouse in Oak Ridge

The "Tree House" - Privacy, Luxury, Nature Views

The elegant "Tree House'' is not in a tree but feels like it, with large windows overlooking lush forest or mountain views. This 450 sf space is a separate unit with own entrance & porch--no stairs! Queen bed, sofa, stone/tile bathroom & walk-in shower, washer-dryer, big TV, fast WiFi, birdfeeders at window. Located on cozy cul-de-sac, reserved parking. This architect-designed space has a kitchenette with fridge, toaster oven, microwave, Keurig coffee, more. Hiking trails near by! Non-smoking.

The navy blue cottage is surrounded by lush greenery, with a stone pathway leading to it. A gazebo is visible nearby, framed by vibrant yellow flowers. The scenic mountains provide a beautiful backdrop against the partly cloudy sky.

4.91 out of 5 average rating, 155 reviews

Million Dollar views of Smokies, Hottub, 30% off!

Now with complimentary EV charging station! 1 mile down the road from Smoky Mountains Park entrance. Our Navy Blue Cottage is a spacious One bedroom tiny house with kitchenette and sitting area in picturesque Wears Valley featuring a country setting with OUT OF THIS WORLD SMOKY MOUNTAIN VIEWS! In the heart of the Smokies with mountain views in a beautiful country setting! This beautiful cottage comes with a private bathroom and deck overlooking the Valley floor and the Great Smoky Mountains.

4.99 out of 5 average rating, 170 reviews

A charming cottage exterior is presented with a welcoming front porch featuring rockers and hanging planters. A brick pathway leads to the entrance, surrounded by landscaped flower beds. The white and black color scheme adds a modern touch to the country setting.

Guesthouse in Loudon

Shiloh Cottage

Slow down and experience country life on our little plot of land. The cottage is located on our 6 acre property with a tree-lined view with cows in the pasture from the front porch and a sweet view of the ducks in the pond and sheep grazing from the bedroom window. We have two Great Pyrenees dogs, a cat, and chickens. There might be occasional barking. If prolonged, we will bring them in. Fully stocked kitchen. There is always plenty of coffee, coffee creamer, and homemade scones for breakfast.

4.99 out of 5 average rating, 194 reviews

Forest Bliss | Private Studio Near Smoky Mountains

Welcome to Smoky Mountain Forest Bliss, your private creekside forest oasis just minutes from Maryville and a scenic drive to the Great Smoky Mountains. Nestled among towering trees and peaceful gardens, this secluded studio apartment offers creek views, a sun/moon deck, walking trails, fire-pit areas, fast Wi-Fi, a cozy queen bed, and a fully equipped kitchen. Perfect for couples, nature lovers, remote workers, and quiet retreat seekers, where comfort meets the calming rhythms of the woods.

4.98 out of 5 average rating, 163 reviews

A wooden deck is presented with two cushioned chairs and a small table, inviting relaxation. The surrounding landscape features rolling hills and distant greenery under a clear blue sky, offering a peaceful view.

Guesthouse in Kodak

Private Loft w/ King Bed Near Gatlinburg/PF/Knox

Welcome to this NEW & private studio loft! Perfect for a quick getaway, this cozy space is nestled on a hill with distant views of the Smoky Mountains. Centrally located in Sevierville, less than 25 miles from Pigeon Forge, Gatlinburg, AND downtown Knoxville. Just minutes from exit 407 on I-40. Close to it all, but away from the congestion. Whether traveling for business or leisure, this location will provide you with a convenient base from which to explore all that East TN has to offer!

4.85 out of 5 average rating, 102 reviews

Freshly Renovated | 1BR Near Dollywood & Trails

Welcome to your perfect Sevierville escape. 🏡 Newly remodeled 1BR/1BA ideal for couples 🛁 Spa-style bathroom for total relaxation 🍳 Full kitchen w/ premium appliances 📍 Minutes to Dollywood & Smoky Mountains ✅ Free parking ✅ High-speed WiFi ✅ Smart TV ✅ Self check-in ✅ Immaculately clean (cleaning fee supports a professional-grade reset after each stay) Our calendar fills quickly — especially during peak season! Book your dates today and make your trip to Sevierville unforgettable.

A charming modern log house is nestled among trees, featuring a metal roof and a welcoming porch. Surrounding greenery and landscaped flower beds enhance the natural setting, providing a serene entrance to the home.

4.98 out of 5 average rating, 227 reviews

Little River Cabin in the Woods

Upon your arrival to this secluded setting, you will find a charming modern log house. No detail has been overlooked in the decor and furnishings to make you feel at home. On the main floor is a generous living area which includes a contemporary kitchen with many amenities, a bathroom with a walk-in shower and a laundry room, if needed. Up the staircase is the loft with a king size bed, a twin XL daybed and a sleeper sofa. Pls note: this property is unsuitable for children 12 and under.

The green cottage is complemented by red shutters and a welcoming entrance. A patio area features a set of black outdoor furniture on a concrete surface, surrounded by natural landscaping including trees and flowering plants, creating a peaceful outdoor setting.

4.99 out of 5 average rating, 324 reviews

US 129 The Dragonfly Cottage ~ Keyless entry!

Cute, comfy cottage, 1bdr/1bath located on US 129 The Dragon. Sleeps 4, 1 qb in private br. 1 full pullout couch in LR (comfy). Full bath, kitchenette. Outside grill. All the amenities supplied. We are just minutes away from The Tail of The Dragon, GSMNP., The Smoky Mtn Speedway. We are 21 minutes from The Shed, 25 minutes from McGhee Tyson Airport, 35 minutes from UT. We are in the country, but still only 15/20 minutes back to town. Watch your speed and animals. We are in the country!!!

4.99 out of 5 average rating, 258 reviews

A welcoming living area features a sleek futon and a woven chair, arranged on a patterned area rug. Natural light fills the space through sliding glass doors, which lead to an outdoor deck, framed by lush greenery visible outside.

Guesthouse in Powell

Private Guesthouse—serene & conveniently located!

Surrounded by woods, this peaceful studio guesthouse provides a retreat-like setting close to our vibrant downtown. The private quarters feature granite countertops, fully-stocked kitchen, separate entrance, comfy bed, sun-filled rooms & a lovely, outdoor seating area to enjoy the quiet. *4 min to Kroger grocery & restaurants *6 min to Tennova North Hospital—perfect for travel nurses! *12 min to downtown *16 min to UT's Neyland Stadium & Thompson Boling Arena *1 hr to the Smoky Mountains

Guesthouse in Fountain City

A cozy sleeping area features a spacious bed with white linens and several pillows, arranged against warm wooden paneling. Soft wall sconces provide gentle illumination. A decorative mirror is positioned above the bed, reflecting light from a nearby window.

4.96 out of 5 average rating, 265 reviews

Private North Knox Guesthouse - close to downtown

In the middle of beautiful trees, this peaceful studio guesthouse provides a refreshing setting very close to downtown. The private quarters feature fresh white linens, fully-stocked kitchen, separate entrance, comfy bed, sun-filled rooms & a lovely, outdoor seating area. *4 min to Kroger grocery & restaurants *11 min to Tennova North Hospital, perfect for travel nurses! *12 min to downtown *13 min to UT's Neyland Stadium & Thompson Boling Arena *50 min to the Smoky Mountains

Superhost

An open concept living space features a cozy gray couch, a wooden coffee table, and a dining area with bar stools. A well-equipped kitchen is visible, including stainless steel appliances. Above, a ladder leads to a lofted sleeping area, while framed artwork adorns the walls.

Guesthouse in Sequoyah Hills

4.91 out of 5 average rating, 752 reviews

New Studio! Foam Bed, Hot Tub, Close to Downtown!

Studio apartment with lofted queen fully-foam mattress, full kitchen with open concept living space in gorgeous historic neighborhood and mile-long riverside park 2 blocks from home, 5 minute uber ride to downtown Knoxville, 1 block from an amazing restaurant (Plaid Apron) and coffee shop (Treetop Coffee), dog friendly with fenced in backyard, and large back deck with hot tub! Close to the University of Tennessee campus, World's Fair Park and Downtown Knoxville.

The image depicts a serene riverbank, where clear water gently flows over smooth stones. Trees line the bank, their bare branches casting soft shadows on the ground. A grassy area and patches of dirt are visible, suggesting a natural, unspoiled environment.

4.99 out of 5 average rating, 163 reviews

Little River Guesthouse at Wildwood Rd.

Bring your fishing rods and kayaks! You will want to extend your stay at this Little River oasis. We built this guesthouse just for visiting guests to enjoy. It has been professionally decorated with handpicked items including some nice vintage and antique finds. Enjoy your morning cup of coffee on the huge deck overlooking the river. This home is close to everything including the Knoxville airport, the Smoky Mountains, Pigeon Forge and Gatlinburg.

Popular amenities for Knoxville guesthouse rentals

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

Family-friendly guest house rentals

The cozy bedroom features sloped ceilings and wooden flooring. A spacious bed is draped in dark bedding, complemented by a textured throw. Natural light enters through a small window, highlighting a seating area and a wooden table in the corner. Shelving units are also present along the walls.

Guesthouse in Strawberry Plains

4.71 out of 5 average rating, 59 reviews

Family-Friendly Cottage | Parking, Kitchen + W/D

An outdoor patio showcases an original water pump positioned over a 20-foot covered well, highlighted by decorative signs and subtle string lighting. The inviting entrance to the cottage can be seen in the background, leading into a cozy interior space.

4.87 out of 5 average rating, 84 reviews

Perfect Cozy Cottage for Couples Getaway

A spacious bedroom features a large bed with a light-colored quilt and decorative pillows. A comfortable chair sits nearby, and soft natural light filters through sheer curtains. A door leads to the bathroom in the background, and a subtle area rug adds warmth to the floor.

4.6 out of 5 average rating, 5 reviews

Mini Historic Farmhouse Stay

A cozy sleeping area features a spacious bed adorned with white quilted bedding and decorative pillows. A bedside table holds a lamp with a warm glow, and a wall-mounted painting adds a touch of nature. Light enters through a window dressed with wooden blinds.

4.76 out of 5 average rating, 21 reviews

La Casita- King Suite, 3 minutes to parkway

4.88 out of 5 average rating, 25 reviews

The exterior of the building is shown, featuring a raised patio with a shaded seating area. The patio is accessed by a set of steps, and the surrounding greenery includes trees and flowers. A clear sky complements the inviting entrance.

Guesthouse in Walland

The Loft

A living area features wooden walls with natural finishes, accompanied by a green three-cushion sofa. A striped accent chair adds color to the space, while a door leads outside. Hooks on the wall display bags, and soft light comes from a nearby lamp.

Guesthouse in Knoxville

5 out of 5 average rating, 3 reviews

La Casita - Cabin vibes

A cozy living space features wood-paneled walls and a plush sofa opposite a comfortable seating chair. A queen bed with decorative bedding is situated near windows that let in natural light. A Jacuzzi tub is located in the corner, and a bedside table with lamps provides soft lighting.

5 out of 5 average rating, 9 reviews

Honeysuckle Cottage near Dollywood

An open living space features a spacious bed with a plaid comforter, complemented by natural light. A dining area with wooden chairs is situated near the kitchen bar, while a staircase leads to the upper level. Decorative artwork is displayed throughout the room.

Guesthouse in Holston Hills

4.67 out of 5 average rating, 3 reviews

Barn Apartment

Guest house rentals with a patio

Guesthouse in Lenoir City

A covered deck is presented, featuring a round table surrounded by four chairs. Soft string lights hang overhead, illuminating the space. The expansive view showcases rolling hills and open pastures, emphasizing the peaceful countryside setting.

4.96 out of 5 average rating, 26 reviews

Country+Convenient to Knoxville/Oak Ridge/Farragut

5 out of 5 average rating, 15 reviews

The kitchenette is equipped with a black sink and a small refrigerator. A microwave is positioned on the countertop, with a potted plant and decorative items displayed on the shelves above. Natural light filters through a window, highlighting the warm tones of the cabinetry.

Guesthouse in Knoxville

The Nomad Treehouse | A South Knox Escape

4.98 out of 5 average rating, 53 reviews

A well-appointed kitchen features white cabinetry and wooden countertops, accented by a stylish tile backsplash. Efficient appliances include a gas stove and a coffee maker. Shelves are stocked with cookware and dinnerware, with soft lighting enhancing the functional space.

Guesthouse in Oak Ridge

Near Rowing-Windrock- UT-ORNL~Atomic Studio

5 out of 5 average rating, 26 reviews

A charming exterior view of a light yellow building featuring large sliding glass doors. Surrounded by a landscaped area, decorative planters with blooming flowers are placed by the poolside, and soft string lights are visible along the eaves.

Guesthouse in Seymour

Poolside Oasis at The Salt House

5 out of 5 average rating, 62 reviews

The image captures a serene view of rolling hills and valleys under a colorful sky at sunrise. Sunlight spills over the mountains, highlighting a misty layer among the trees. Various shades of green foliage are visible in the foreground, contributing to the tranquil atmosphere.

Guesthouse in Tallassee

Smoky Mountain High -Top of the World

Guesthouse in Lenoir City

A modern guest house is surrounded by lush greenery, featuring a spacious wrap-around deck with several seating options and an umbrella-covered table. A gravel driveway leads to the entrance, framed by trees that provide a serene backdrop.

5 out of 5 average rating, 11 reviews

Modern private chalet in the woods 2 bathrooms

5 out of 5 average rating, 19 reviews

Guesthouse in Knoxville

Private guest house convenient to Downtown and UT

4.96 out of 5 average rating, 55 reviews

A wooden deck features a small table with colorful chairs, inviting outdoor seating. The entrance to the cottage includes steps leading up to the deck. The building is surrounded by trees, creating a natural, serene setting.

Guesthouse in Powell

Cozy Cottage

Guest house rentals with a washer and dryer

5 out of 5 average rating, 21 reviews

The exterior showcases a modern brick facade with three large garage doors, allowing for plenty of natural light. Surrounding greenery enhances the tranquil setting, while a spacious driveway offers easy access. The structure is framed by tall trees, providing a serene and peaceful environment.

Guesthouse in Louisville

Forest Hideaway in Louisville

A spacious living room is showcased with a plush couch and wooden coffee table at its center. A decorative rug enhances the warmth of the room, while a mounted television provides entertainment. A cozy fireplace adds a touch of comfort to the inviting atmosphere.

4.91 out of 5 average rating, 392 reviews

Dollywood 10 min • Dog stays free • Kitchen & W/D

Guesthouse in Oliver Springs

The exterior of the apartment is displayed, featuring a light-colored structure with a dark metal roof. A gravel driveway leads up to the building, surrounded by trees and foliage. Decks are visible on either side, providing outdoor space for relaxation.

4.95 out of 5 average rating, 19 reviews

Guest House 10 mins to Windrock

4.92 out of 5 average rating, 177 reviews

Relax in a Smoky Mtn getaway near Knoxville

A screened-in porch is featured at the entrance, constructed with wooden railings and steps. Surrounding the porch, a well-maintained gravel yard includes a rock border and two green Adirondack chairs, offering an inviting space for relaxation.

4.98 out of 5 average rating, 59 reviews

The Old Homeplace

The exterior entrance features two vibrant red French doors, leading into the cottage. Surrounding the entrance, colorful flowers bloom in pots, adding a lively touch. Blue chairs are placed on each side of the doorway, providing a welcoming spot to relax.

4.98 out of 5 average rating, 285 reviews

“LaLa’s Place” A li’l cottage by the 100yr old BRG

A small white table is situated between two brown chairs, illuminated by natural light from large windows. A vase of fresh flowers is centered on the table, while a book lies open beside it. Outside, a scenic view of green fields and mountains can be seen.

5 out of 5 average rating, 80 reviews

Cooper's Nest at Butterfly Gap