Guesthouse vacation rentals in Knoxville

Find and book unique guesthouse rentals on Airbnb

Top-rated guesthouse rentals in Knoxville

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Top guest favorite

The exterior of the Tree House showcases a modern architectural design with large windows that invite natural light. A welcoming porch extends from the unit, featuring wooden railings and hanging wind chimes, surrounded by lush greenery.

Guesthouse in Oak Ridge

4.98 out of 5 average rating, 379 reviews

The "Tree House" - Privacy, Luxury, Nature Views

The elegant "Tree House'' is not in a tree but feels like it, with large windows overlooking lush forest or mountain views. This 450 sf space is a separate unit with own entrance & porch--no stairs! Queen bed, sofa, stone/tile bathroom & walk-in shower, washer-dryer, big TV, fast WiFi, birdfeeders at window. Located on cozy cul-de-sac, reserved parking. This architect-designed space has a kitchenette with fridge, toaster oven, microwave, Keurig coffee, more. Hiking trails near by! Non-smoking.

Guest favorite

A private jacuzzi tub is visible, surrounded by lush greenery and trees. Soft, multicolored lights illuminate the water, creating a calming ambiance. The twilight sky can be seen above, adding to the serene atmosphere of the outdoor space.

Guesthouse in Sevierville

4.92 out of 5 average rating, 134 reviews

Million Dollar views of Smokies, Hottub, 30% off!

Now with complimentary EV charging station! 1 mile down the road from Smoky Mountains Park entrance. Our Navy Blue Cottage is a spacious One bedroom tiny house with kitchenette and sitting area in picturesque Wears Valley featuring a country setting with OUT OF THIS WORLD SMOKY MOUNTAIN VIEWS! In the heart of the Smokies with mountain views in a beautiful country setting! This beautiful cottage comes with a private bathroom and deck overlooking the Valley floor and the Great Smoky Mountains.

Top guest favorite

A charming cottage exterior is presented with a welcoming front porch featuring rockers and hanging planters. A brick pathway leads to the entrance, surrounded by landscaped flower beds. The white and black color scheme adds a modern touch to the country setting.

Guesthouse in Loudon

4.99 out of 5 average rating, 122 reviews

Shiloh Cottage

Slow down and experience country life on our little plot of land. The cottage is located on our 6 acre property with a tree-lined view with cows in the pasture from the front porch and a sweet view of the ducks in the pond and sheep grazing from the bedroom window. We have two Great Pyrenees dogs, a cat, and chickens. There might be occasional barking. If prolonged, we will bring them in. Fully stocked kitchen. There is always plenty of coffee, coffee creamer, and homemade scones for breakfast.

Top guest favorite

Guesthouse in Maryville

4.98 out of 5 average rating, 269 reviews

LaLa’s Place a country cottage ~near to all

LaLa's place is a cozy, comfortable cottage, in the quiet countryside of Maryville TN, in the foothills of the Great Smoky Mountains! Ideal for couples, small families, Bikers, solo adventures, hikers, kayakers & pet lovers who wish to travel with their SMALL dog. Off rte 129, near the Dragon & Tellico Lake, in the foothills of the Great Smoky Mountains; over the 100 year old bridge, on Nine Mile Creek, on a dead end rd with over 6 acres; surrounded by open pastures. Only 4 miles to town

Superhost

An inviting country guesthouse is illuminated softly against a dark sky filled with clouds. A staircase leads to the upper deck, where warm light spills out from the windows. Subtle outdoor lighting enhances the surrounding lawn, creating a serene atmosphere.

Guesthouse in Mascot

4.84 out of 5 average rating, 515 reviews

Quaint country cottage

A newly remodeled country gusthouse with one bedroom, 1 bath. It has a fully stock kitchen, bathrooms, and linens. Comes with Wi-Fi and two televisions with DIRECTV. you'll be 5 minutes to House Mountain Park, with 527 acres of breathtaking views, trails, picnic area, free parking, and public restrooms. 20 minutes to Downtown Knoxville, Exit 407, featuring The Great Smokey Mountains, Gatlinburg, Dollywood, & The Sky Bridge also 25 min. to 4 lakes Cherokee/Douglas/Norris & Ft. Loudon.

Top guest favorite

An exterior view of the Titanic Museum is presented at dusk, showcasing its replica ship structure, which features large orange smokestacks. Soft lights illuminate various sections, and guests can be seen walking towards the entrance, enhancing the atmosphere of this popular attraction.

Guesthouse in Kodak

4.98 out of 5 average rating, 120 reviews

Private Loft w/ King Bed Near Gatlinburg/PF/Knox

Welcome to this NEW & private studio loft! Perfect for a quick getaway, this cozy space is nestled on a hill with distant views of the Smoky Mountains. Centrally located in Sevierville, less than 25 miles from Pigeon Forge, Gatlinburg, AND downtown Knoxville. Just minutes from exit 407 on I-40. Close to it all, but away from the congestion. Whether traveling for business or leisure, this location will provide you with a convenient base from which to explore all that East TN has to offer!

Top guest favorite

A charming modern log house is nestled among trees, featuring a metal roof and a welcoming porch. Surrounding greenery and landscaped flower beds enhance the natural setting, providing a serene entrance to the home.

Guesthouse in Maryville

4.98 out of 5 average rating, 213 reviews

Little River Cabin in the Woods

Upon your arrival to this secluded setting, you will find a charming modern log house. No detail has been overlooked in the decor and furnishings to make you feel at home. On the main floor is a generous living area which includes a contemporary kitchen with many amenities, a bathroom with a walk-in shower and a laundry room, if needed. Up the staircase is the loft with a king size bed, a twin XL daybed and a sleeper sofa. Please note: this property is unsuitable for infants or children.

Top guest favorite

The living area is adorned with a cozy black leather couch and a wooden coffee table atop a patterned rug. A large television is mounted on the wall, opposite a spacious bed visible in the background, with double doors leading to an outdoor deck.

Guesthouse in Powell

4.99 out of 5 average rating, 213 reviews

Private Guesthouse—serene & conveniently located!

Surrounded by woods, this peaceful studio guesthouse provides a retreat-like setting close to our vibrant downtown. The private quarters feature granite countertops, fully-stocked kitchen, separate entrance, comfy bed, sun-filled rooms & a lovely, outdoor seating area to enjoy the quiet. *4 min to Kroger grocery & restaurants *6 min to Tennova North Hospital—perfect for travel nurses! *12 min to downtown *16 min to UT's Neyland Stadium & Thompson Boling Arena *1 hr to the Smoky Mountains

Top guest favorite

The entrance features a white door framed by a decorative wrought iron security door, adorned with a green wreath. A small wooden table is positioned beside the door, flanked by lush greenery and a potted plant on the step.

Guesthouse in Fountain City

4.95 out of 5 average rating, 190 reviews

Private North Knox Guesthouse - close to downtown

In the middle of beautiful trees, this peaceful studio guesthouse provides a refreshing setting very close to downtown. The private quarters feature fresh white linens, fully-stocked kitchen, separate entrance, comfy bed, sun-filled rooms & a lovely, outdoor seating area. *4 min to Kroger grocery & restaurants *11 min to Tennova North Hospital, perfect for travel nurses! *12 min to downtown *13 min to UT's Neyland Stadium & Thompson Boling Arena *50 min to the Smoky Mountains

Guest favorite

A wooden deck features a hot tub surrounded by a shaded seating area with colorful cushions. Nearby, a hammock stand is visible, and the lush greenery of the backyard complements the serene setting. The space invites relaxation and enjoyment of the outdoors.

Guesthouse in Knoxville

4.92 out of 5 average rating, 723 reviews

New Studio! Foam Bed, Hot Tub, Close to Downtown!

Studio apartment with lofted queen fully-foam mattress, full kitchen with open concept living space in gorgeous historic neighborhood and mile-long riverside park 2 blocks from home, 5 minute uber ride to downtown Knoxville, 1 block from an amazing restaurant (Plaid Apron) and coffee shop (Treetop Coffee), dog friendly with fenced in backyard, and large back deck with hot tub! Close to the University of Tennessee campus, World's Fair Park and Downtown Knoxville.

Top guest favorite

An outdoor deck is furnished with a seating area that includes two armchairs, a loveseat, and a fire table. A dining table for two is situated nearby, shaded by a blue umbrella. The deck is surrounded by lush greenery, enhancing the natural setting.

Guesthouse in Maryville

4.99 out of 5 average rating, 146 reviews

Little River Guesthouse at Wildwood Rd.

Bring your fishing rods and kayaks! You will want to extend your stay at this Little River oasis. We built this guesthouse just for visiting guests to enjoy. It has been professionally decorated with handpicked items including some nice vintage and antique finds. Enjoy your morning cup of coffee on the huge deck overlooking the river. This home is close to everything including the Knoxville airport, the Smoky Mountains, Pigeon Forge and Gatlinburg.

Guest favorite

A circular wooden sign features the name 'Knoxville' prominently, accompanied by stylized mountains and waves. Surrounding details include leaves and branches, enhancing the natural theme of the piece.

Guesthouse in North Knoxville

4.95 out of 5 average rating, 225 reviews

Charming Retreat 4.2 miles from Downtown

It is perfect for mid-term and long-term stays for couples traveling with one child, college students, remote workers, and more. Wifi and Ethernet Connection 3.8 - 5.2 Miles / 8-12 Minutes to Downtown (Depends on Traffic) 3-5 Minutes to Grocery store 3-5 Minutes to Restaurants and Fast food 15 Minutes to Hikes/Attractions 20 Minutes to the Airport 31- 34 Miles / 45 Minutes to Pigeon Forge 39 - 42 Miles / 50 Minutes to Gatlinburg