
House vacation rentals in Grimes
Find and book unique houses on Airbnb
Quick stats about house rentals in Grimes

Total vacation rentals
Explore 40 vacation rentals in Grimes

Nightly prices starting at
Grimes vacation rentals start at G$4,177 GYD per night before taxes and fees

Verified guest reviews
Over 1,240 verified reviews to help you choose

Family-friendly vacation rentals
30 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 10 rentals that welcome pets

Rentals with dedicated workspaces
20 properties have a dedicated workspace

Wi-Fi availability
40 of Grimes vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Grimes rentals

4.8 Average rating
Grimes stays are highly rated by guests—averaging 4.8 out of 5!
Top-rated house rentals in Grimes
Guests agree: these houses are highly rated for location, cleanliness, and more.

MidCentury, technicolor Ranch w/yard, w+d, parking
- Ranch home in Des Moines' friendly Beaverdale neighborhood - Steps from grocery store, ice cream shop+dining - Blocks to more dining+shops - Less than 5 minutes from Drake University - Around 10 minutes from downtown, Des Moines, Arts Center, parks - Easy access within 15 minutes to suburbs - 1000+ feet with open living, dining and kitchen, 2 beds, 1 bath, laundry and on-site parking - Outdoor front porch, back patio+fire pit - Perfect for a family or two couples ***Send your special requests!

Remodeled Brick Home close to everything
Your family will be close to everything when you stay at this centrally located home. Located one mile from the Des Moines Airport (stay and Park possible) next to a main street just three short miles to downtown. Multiple restaurants and grocery stores within walking distance. Near Des Moines Water Works Park and Grays Lake recreational area. Newly renovated top to bottom. Includes two spacious bedrooms on the main floor and two bedroom areas in the basement, and a full bathroom on each level.

Sleeps 12 | Hot Tub | Air Hockey | 3.5 Baths
Bring the whole crew to this spacious 3-level Urbandale home — ideal for family reunions, group getaways, or Des Moines sports weekends. Soak in the year-round hot tub after a long day, then challenge everyone to air hockey in the walk-out basement rec room. Spread out across 4 bedrooms and 3.5 baths with fast fiber WiFi and 65" smart TVs in both living areas. The fenced backyard and quiet suburban street are perfect for kids and pets. Minutes from downtown Des Moines and the Jordan Creek Mall.

The Hidden Lodge - Wooded Lot w/ Firepit & Games!
The Hidden Lodge is a 5-bed, 3-bath retreat nestled on a wooded lot near Saylorville Lake. This is a great location to stay with families, friends, or for contractors/work travel. The Lodge offers a cozy getaway with modern amenities and a touch of rustic charm. The basement features a pool table, darts, and board games for your entertainment. Outdoor spaces include a deck with a serene view, and a large fire pit to enjoy the area. Contact us to inquire about seasonal or contractor discounts!

Sassy, Fun, Adult Getaway! Gameroom!
Prof. designed w/feminine sass, this space has so many details to make you smile! From the cuss word coffee bar to the game room, to the aromatic scent bar to the adult themed card/board games, to the choice of soft cheetah print robes & luxurious throw blankets, no detail has been left out. Walking dist. to restaurants, bars, coffee shops, grocery stores, a spa/nail place & easy access to the bike trails & I235. 10 mins to downtown DSM or the nightlife of West Glen. Super safe, quiet nbrhood.

Drake neighborhood cottage
Great location, close to Drake University (less than 2 miles). Two Master, King bed bedrooms each with newly renovated bathrooms, with beautiful tile showers and smart toilets. This is a cozy home that is perfect for four adults, or a family of four. Newly remodeled kitchen with new refrigerator, gas range and dishwasher. Hardwood floors throughout the home, with tiled kitchen and baths. Conveniently located within a short walk to the Waveland Cafe (300 ft), a favorite breakfast spot.

RARE Mid-Mod Home. Spacious inside-and-out.
Don't miss your chance at this unique mid-century modern home located in the heart of Des Moines where you'll be just minutes from many local restaurants, bars and area attractions. Entertain your guests with 3,600sf of open-concept mid-century living while enjoying all the amenities this house has to offer! Relish in billiards indoors or escape outdoors for yard games, grilling or an evening bonfire. This newly remodeled 4 bed, 2.5 bath property has everything you need on your next vacation.

Peaceful oasis, private wooded back yard, games
You'll love this well appointed 3 BR mid-mod styled home, located in a quiet neighborhood yet just minutes from everything. Also located next to an extensive walking & biking trail. Cook for the family from the well equipped kitchen. Stream your favorite show on one of the 2 living areas with smart 55 & 65in TVs. Lower level has Ms PacMan arcade game, ping pong, air hockey and board games. Gas grill & eating area on the stone patio. Nearby are several dining & shopping options. Welcome Home!

Effortless Landing near Airport & Downtown
Welcome to the Effortless Landing! Our super clean and comfy, Boho style retreat. Private keyless entry with off street parking. Enjoy a queen bed, additional pull out queen bed in couch, local coffee, & all the amenities like fiber wifi, TV, linens, full kitchen, & laundry. Add that to the wonderful surroundings of the city of Des Moines, in a quiet, centrally located neighborhood. Conveniently located 4 minutes from the Des Moines International Airport, & 7 minutes to Downtown Des Moines!

Cozy Historic Escape
This comfortable bungalow is stylish with historic charm. The front porch is perfect for morning coffee. The main living space has original hardwood floors and classic brick fireplace with craftsman style built-ins. The house also has fenced in backyard with patio for enjoying temperate days. It is centrally and conveniently located close to Des Moines Playhouse, ~6 minutes from Casey’s Center and Downtown Des Moines, ~13 minutes to Jordan Creek Town Center, and ~15 minutes to DSM Airport.

Peaceful Setting & Modern Style
Escape the hustle and bustle of the city and retreat to your own private oasis with this charming 2 Bedroom Airbnb. The house provides present-day amenities while still honoring the original 1930s character. You’ll enjoy a new and sparkling clean kitchen, complete with all the appliances and utensils you need. The bathroom, laundry, dining room, reading nook and living room have all been beautifully updated as well, ensuring that you'll feel right at home from the moment you arrive.

Arcade Room /Backyard/BBQ*Kings*Private
Located in a well-established neighborhood near Valley Junction, this centrally located home keeps you close to restaurants, shopping, and local favorites. Just steps from the Willow on Grand wedding venue, it’s perfect for families or groups wanting comfort and convenience. Enjoy a spacious living room, large dining area for gatherings, and a backyard with a fire pit—ideal for relaxing evenings together. Thoughtfully designed to make you feel right at home while still on vacation!
Popular amenities for Grimes house rentals
House rentals with a pool

New Arrival Peaceful Comfort Calm & Private

Comfortable and Spacious Five Bedroom Home

Urbandale Oasis

Huge Home, Gym, Game Room, Spa, BBQ, Near I-35

Summer House DSM

Urban Oasis with Pool & Hot Tub + Fast WiFi

Luxury Getaway! The University

Grimes Getaway with pool
Weekly house rentals

Cheerful 3 bedroom home in a quiet small town

Private Cottage Retreat | Fire Pit, Fenced Yard

Petal Place

Saylorville ~ Tesla Charger

Maggie's Place

Rest At Ease in Ankeny

Gardens on Grand

• Iconic Lustron home with 2 king beds •
Private house rentals

Fresh Remodel! Whole House Getaway Near DSM!

The Draper-MCM Spacious Ranch minutes to it all

Luxe New Home near interstate (sleeps 6)

King Bed - 1948 Mid-century Lustron - 2 Car Garage

Sleeps 10, Fire pit, Outdoor Eating & Grill, Gym

Private 7-Acre Estate with Hot Tub & Pond

New 3-Bedroom Residential Home w/ Parking

The Holcomb House: A City Escape-NEW PATIO & GRILL
When is the best time to visit Grimes?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$32,582 GYD | G$31,955 GYD | G$32,373 GYD | G$37,595 GYD | G$40,727 GYD | G$41,981 GYD | G$42,189 GYD | G$41,981 GYD | G$35,088 GYD | G$39,265 GYD | G$36,550 GYD | G$33,208 GYD |
| Avg. temp | -5°C | -3°C | 4°C | 11°C | 17°C | 22°C | 24°C | 23°C | 19°C | 12°C | 4°C | -2°C |
Destinations to explore
- St. Louis Vacation rentals
- Minneapolis Vacation rentals
- Kansas City Vacation rentals
- Omaha Vacation rentals
- Des Moines Vacation rentals
- Saint Paul Vacation rentals
- Sioux Falls Vacation rentals
- Lincoln Vacation rentals
- Madison Vacation rentals
- Wisconsin Dells Vacation rentals
- Overland Park Vacation rentals
- Lake Geneva Vacation rentals





