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House vacation rentals in Greenville

Find and book unique houses on Airbnb

Top-rated house rentals in Greenville

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Guest favorite
A modern living area features a light blue sectional sofa with varying cushions, positioned facing a wall-mounted TV above a linear fireplace. A wooden coffee table is centered on the floor, with two barstools at the kitchen counter in the background.
Home in Greenville
4.99 out of 5 average rating, 138 reviews

Close to downtown & village, 2 king beds, updated!

Built in 1945, the Cotton Mill Cottage is a fully renovated mill house that provide modern comfort and convenience while retaining its charm and character. Directly across from the mill where "Shoeless" Joe Jackson worked, that at one time helped make Greenville the world's textile capital, there is no better place to soak in the industrial history of this lively neighborhood. The unique shape and position of the lot makes the home feel very private and quiet while still being close to the fun!

Guest favorite
Home in Greenville
4.99 out of 5 average rating, 186 reviews

Modern Designer Getaway Near Downtown Greenville

Welcome to your Greenville getaway! Minutes from downtown, GetawayGVL is a designer 1950s midcentury modern ranch that offers the conveniences of a hotel with the comforts of home. This bright and airy 3BR, 1.5BA tropical oasis boasts a stunning outdoor space with yard games for entertaining, a dedicated desk for working, and a designer den for relaxing. You're only minutes away from a walk on the Swamp Rabbit Trail, dinner by the Reedy River, or a concert at The Well! Book your getaway today!

Superhost
A cozy living area features a leather couch adorned with pink cushions, positioned near a decorative glass coffee table. Sunlight filters through the windows, illuminating a flat-screen television above a white mantel. A small side table and a bookshelf add functional charm to the space.
Home in Greenville
4.82 out of 5 average rating, 164 reviews

Fenced in Yard, 2 Queen Beds, Downtown!

Hard to beat this amazing value! Nestled on a quiet street 5 minutes from downtown, this 2bed/1bath property is perfect for your visit to Greenville. Each bedroom has a queen bed and plenty of closet space with hangers. Out back, there's a spacious deck to relax on, and the property has a fenced in yard which would be ideal for your curious furry friend. This property is minutes from hospitals & interstate 85. Ideal for work travelers, or simply curious visitors. There's a driveway for parking.

Top guest favorite
A modern one-story ranch house is depicted in a tranquil setting, featuring a spacious driveway and manicured landscaping. Natural light illuminates the exterior, enhanced by a welcoming entryway with decorative planters and a covered porch, surrounded by lush greenery and large trees.
Home in Travelers Rest
5 out of 5 average rating, 138 reviews

Modern Wooded Retreat

Come enjoy this modern, 1.6 acre retreat! Relax with the whole family in a place you'll never want to leave. Located 5 min. to downtown TR and less than 20 min to downtown Greenville! Roast marshmallows by the firepit, play yard jenga, connect 4 and cornhole in the fully fenced, dog friendly back yard. Close to the swamp rabbit trail, and centrally located to lakes, hiking, fishing and exciting nightlife. Let us host you, while you explore everything Greenville and Travelers Rest have to offer.

Top guest favorite
The exterior of a stand-alone home features a welcoming front porch with seating. Lush greenery and colorful landscaping enhance the entrance, while a clean, paved path leads to the door. The house, characterized by a classic design, showcases well-maintained siding and contrasting shutters.
Home in Greenville
4.99 out of 5 average rating, 198 reviews

Clean, cozy, well appointed house near downtown

Come stay at this private, stand-alone home that has earned its nickname "Perrydise" It's maintained to the highest standards of cleanliness and hygiene. Elegant, well-appointed, & fully equipped so you can feel at home and work remotely as you need to (house-wide Wi-Fi and laptop friendly work spaces). Very close to Cherrydale Point Mall with grocery & take-out restaurants,. Location is close to everything including Furman Univ., downtown Greenville, Swamp Rabbit Trail. (no smoking, no pets)

Top guest favorite
An open-concept living area features a modern kitchen with stainless steel appliances and a spacious island, complemented by a dining table. A cozy living room is equipped with a soft sectional sofa facing a mounted television and warm electric fireplace. Natural light enhances the inviting atmosphere.
Home in Greenville
4.98 out of 5 average rating, 117 reviews

Greenville GEM Luxurious Retreat in Prime Location

Beautifully renovated 3 beds, 2 baths haven! This gem is a tranquil & stylish retreat, blending modern & cozy charm. Spacious bedrooms, each with plush bedding and storage. Two Bathrooms with soaking tub and a spacious walk-in shower. Cozy living room with a fireplace, TV, and comfy seating.  Fully equipped kitchen, Wi-Fi, Private deck and gazebo, fenced yard. Close to the city's best attractions, dining, and entertainment options. This is the perfect home base for your Greenville adventures.

Top guest favorite
The front of the house is showcased with a white exterior and a welcoming porch. Two rocking chairs are positioned on the porch, surrounded by planters displaying seasonal flowers. A well-maintained pathway leads to the entrance, framed by decorative brick steps and a railing.
Home in Greenville
4.97 out of 5 average rating, 232 reviews

Spectacular home 1 mile from Main St Greenville!

Enjoy your stay in this charming up to date house 1 mile from Main St Greenville! Take a walk through the Historic Pinckney district on your way to Greenville’s museums, restaurants, theaters, and stunning Reedy River Falls Park. Easy access to the Swamp Rabbit biking and walking trail, and just 4 blocks from the upcoming Unity Park. House is located on quiet residential street with private driveway. Relax on rocking chairs on front porch or around a portable fire pit in large backyard.

Top guest favorite
The exterior of the mill home is captured, showcasing a single-story structure with light blue siding and white trim. A covered porch is visible, surrounded by low-maintenance landscaping. Nearby trees provide a natural backdrop, and the overall setting conveys a quiet neighborhood atmosphere.
Home in Greenville
4.99 out of 5 average rating, 116 reviews

Cozy Swamp Rabbit - Sans Souci Greenville Furman

Welcome to Greenville - 1500 sq ft mill home in Sans Souci area. 5 min to downtown Greenville, quiet area - 10 min to Travelers Rest w bakeries, restaurants, shops, Furman. Half-mile to famous Swamp Rabbit Trail / Cafe (bike/walk). Explore GVL on the two provided bikes. Work here - fast wi-fi. Charge EV using 14-50 AMP port Tesla / other EVs. Hike with SC State Park - All Park Pass - free entry to all 47 SC State Parks. Create an adventure, visit or test-live in Greenville.

Guest favorite
A spacious living room features a large sectional sofa adorned with various pillows. A stylish floor lamp stands next to the sofa, while a coffee table with decorative items sits nearby. A potted plant adds a touch of greenery, and light streams in through a window with soft curtains.
Home in Greenville
4.95 out of 5 average rating, 147 reviews

Stylish 3BR Home: Pet-Friendly, Outdoor Lounge

Welcome to Chardonnay Chateau, a stylish 3 bedroom, 2 bathroom home just 3 miles from Downtown Greenville. We are conveniently located next to: Shops at Cherrydale (0.7 mi) Downtown Greenville (3.5 mi) Bon Secours Wellness Arena (3.5 mi) Downtown Traveler's Rest (7 mi) Our home provides ample space to enjoy with your loved ones, including a converted carport that is now used as a place to rest and rejuvenate in the outdoors. We can’t wait to welcome you into our home!

Top guest favorite
A charming exterior view of the home features light beige siding and a welcoming blue front door. Windows with blinds allow natural light to brighten the interior. The manicured front yard includes low shrubs, and a concrete walkway leads to the entrance.
Home in Greenville
4.94 out of 5 average rating, 112 reviews

Greenville Modern Retreat - 8 minutes to Downtown

Decorated in a mid century modern theme, this home is perfect for couples and business travelers looking for a peaceful, modern aesthetic filled with natural light. This home is located in San Souci just 2.5 mi (8min drive) to downtown Greenville. It is also conveniently located 1/2 mi to the Swamp rabbit trail and the Swamp Rabbit Grocery. Please see “Where you’ll be” section for further description of location and the neighborhood. We're excited to have you join us!

Top guest favorite
The treehouse structure features a distinctive A-frame design with large glass paneling allowing for abundant natural light. Surrounded by trees, an outdoor deck with seating complements the lush woodland setting. The rooftop deck above adds to the unique architectural appeal.
Home in Greenville
4.99 out of 5 average rating, 224 reviews

Cozy Treehouse

Situated at the back of a wooded 2 acre lot, only 10 minutes from downtown Greenville, this is a little oasis in the city! While most treehouses take you on a "roughing it" adventure, Cozy Treehouse is the glamping version of treehouses, boasting 9' ceilings, 1.5 baths, 3 LED TV's and many outdoor living options. If you are looking for a unique getaway just minutes from one of the top growing cities in the south, Cozy Treehouse is the perfect destination for you.

Top guest favorite
A spacious living area is showcased with two modern sofas adorned with decorative cushions. A wooden coffee table sits in the center, accompanied by a selection of magazines. Light filters through multiple windows, illuminating the hardwood flooring and subtle decor.
Home in Greenville
4.98 out of 5 average rating, 514 reviews

Ultra Luxury Downtown House, Voted GVL's #1 AirBnb

Walking distance to everything, yet quiet at night. Luxury downtown living. Gourmet kitchen with chef appliances and wine fridge, living area with flat screen TV, one king bedroom and twin bedroom (2 beds) and bath. Ample parking for guest (Rare for downtown). Perfect accommodation for couples or business travelers. Walking distance to restaurants and bars, grocery store and drug store in central business district. Half bath is located in the garage.

Popular amenities for Greenville house rentals

When is the best time to visit Greenville?

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Avg. priceG$27,393 GYDG$26,975 GYDG$27,393 GYDG$27,184 GYDG$28,020 GYDG$26,975 GYDG$27,184 GYDG$26,975 GYDG$26,975 GYDG$29,275 GYDG$29,066 GYDG$28,230 GYD
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Quick stats about house rentals in Greenville

  • Total vacation rentals

    Explore 590 vacation rentals in Greenville

  • Nightly prices starting at

    Greenville vacation rentals start at G$2,091 GYD per night before taxes and fees

  • Verified guest reviews

    Over 27,370 verified reviews to help you choose

  • Family-friendly vacation rentals

    460 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 280 rentals that welcome pets

  • Vacation rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    350 properties have a dedicated workspace

  • Wi-Fi availability

    580 of Greenville vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Greenville rentals

  • 4.9 Average rating

    Greenville stays are highly rated by guests—averaging 4.9 out of 5!

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