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Vacation rentals in Geneseo

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Geneseo

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A historic brick building is showcased, featuring ornate arched windows and a decorative façade. The structure includes a ground-level entrance with signage, while bicycles and outdoor seating are visible nearby. Traffic signals and a crosswalk are evident in the foreground.
Apartment in Galesburg
4.92 out of 5 average rating, 606 reviews

Downtown apt. 8

I bedroom apartment in historic downtown building. 2 blocks from Knox College; 3 blocks from Amtrak Station. Several good restaurants and bars nearby; downtown Y a block away. 12' ceilings, hardwood floors, full kitchen and bathroom, coin laundry down the hall. Heat from radiators. Window AC units in summer. TV in bedroom. (For some reason, the listing says 4 beds; that is incorrect.) The apt. is on the 2nd floor: 26 steps. (No elevator.) Parking in lot across the street. Host lives nearby.

Top guest favorite
Home in Le Claire
4.96 out of 5 average rating, 435 reviews

Aire Leclaire 2-bedroom home

Your family will be close to everything when you stay at Aire Leclaire! Within walking distance from downtown and 2 blocks from American Pickers. This modern 2 bedroom, 1 bath home is a block away from the tugfest parade route. A barnyard turned farmhouse in the 1940’s, this home completely remodeled with the modern farm charm it has today. In town for a day or several, enjoy outdoor amenities, a lighted deck, outdoor couch, and table. Inside, a modern LED fireplace mixed with rustic beauty.

Top guest favorite
The exterior of the home features a tan façade with green shutters on the windows. A concrete pathway leads to the entrance, which includes a porch with steps. The surrounding area is beautifully landscaped with a grassy lawn and flower beds, offering a serene view of the neighborhood.
Home in Geneseo
4.99 out of 5 average rating, 107 reviews

Groovy 60s Themed House

Enjoy this completely remodeled home that’s a step back in time. Filled with 60s decor, style and flare with modern amenities and the comfort of home. Step into the lower level to shoot some pool or relax with tunes on the record player. A spacious deck overlooks a wooded area for a relaxing quiet night. The Airbnb house is owned by C&S Antique Mall - which is open daily for your shopping fix. Just minutes from historic downtown and close to restaurants and shopping, the location is perfect.

Top guest favorite
A modern cabin is set on a landscaped lot with a gravel path leading to the entrance. The structure features a mix of dark siding and wood accents, surrounded by open fields and distant tree lines, offering a serene rural setting.
Cabin in Princeton
4.96 out of 5 average rating, 162 reviews

Private & Modern. Near river and wildlife refuge!

Experience the outdoors in comfort from this modern cabin, situated next to the 2200 acre Princeton Wildlife Management Area, and the nearby Mississippi River. It is ranked as the most “Wish Listed” Iowa listing of 2025 on Airbnb. Are you into hiking, biking, fishing, hunting, boating, or other water, winter, and summer sports? This cabin can support it all! Sit back and relax on the large deck while enjoying a coffee & the local wildlife, flora, & fauna of the Mississippi Valley Region.

Top guest favorite
The entrance features a welcoming porch with a ceiling fan and decorative lights. A white picket fence includes a painted flower sign, while steps lead to a green door framed by large windows. Rocking chairs are placed on the porch, inviting relaxation.
Cottage in Le Claire
4.97 out of 5 average rating, 242 reviews

Grasshoppers Guest House Too, cozy, cute, cottage!

This cozy cottage is 1000 sq. feet of charm. You are in the heart of downtown, historical Le Claire. Your home away has everything you will need for your stay. The porch overlooks downtown, nestled in with views of the Mississippi River. Shops, dining, brewery & distillery all to enjoy. visitleclaire.com has monthly activities & festivities. Birthplace of Buffalo Bill Cody & home to Mike Wolfe on American Pickers. You may even see him unloading treasures at his shop Antique Archaeology!

Top guest favorite
The Mill House, a historic green building with yellow trim, features two stories and a stone foundation. The year '1881' is displayed prominently on the facade. A balcony with decorative hanging plants is visible, along with landscaping that includes a signpost and a grassy area.
Apartment in Le Claire
4.93 out of 5 average rating, 304 reviews

Old Mill House - (two bedroom) - on the river!

Historic Leclaire, Iowa is full of quaint shops, antiques, and variety of restaurants. Walking distance (only 175 steps to the Green Tree Brewery), Mississippi River Distillery, Wide River Winery, and the History Channel's ..the American Pickers. Check out our OTHER listing - the "Captain's Quarters" - in the same historic building on the top floor 1 bedroom with king bed! Voted in 2019 River Travel Magazine as one of the top 5 "Most Romantic Getaways" along the Mississippi River.

Superhost
A waterfront area features several gray lounging chairs arranged around a fire pit, with views of a spacious wooden deck and a house in the background. Trees provide shade, and a hot tub is visible near the deck.
Home in Hampton
4.88 out of 5 average rating, 145 reviews

Hampton House w/ Mississippi Hot Tub Views!

The Hampton House is located right on the Mississippi and minutes away from the Home of the American Pickers(History Channel) Looking for a getaway with beautiful views! This house offers sunset views from the kitchen, living room and master suite. Feel right at home with amenities including a Keurig coffeemaker, fully equipped kitchen, smart TV’s, fresh linens and towels as well a washer & dryer on site.After a long day out exploring nothing beats our brand new jacuzzi hot tub!

Top guest favorite
An open living area is highlighted by a spacious seating arrangement featuring brown leather sofas and a wooden coffee table. Large windows are adorned with checkered curtains, allowing natural light to fill the space. A dining area with a marble-top island and barstools is visible.
Townhouse in Geneseo
4.98 out of 5 average rating, 94 reviews

The Mill

Centrally located on State Street in Geneseo. State Street is the main drag with many local shops and restaurants literally next door. This beautifully renovated unit from 1907 offers 2 bed/1 bath, fully updated kitchen with stainless steel appliances including range, oven, dishwasher, and full-size side by side refrigerator. 4 seated kitchen island for dining area open to the living room. Private laundry and desk/work space also available inside unit.

Guest favorite
Apartment in Moline
4.86 out of 5 average rating, 138 reviews

Downtown Moline- Pac Man, Patio & Retro Feels

Step into a bold retro retreat in the heart of downtown Moline! Enjoy cozy fall nights by the firepit, play Pac-Man, or unwind in vibrant vintage style. ✨ What You’ll Love: • 🏙️ Prime Location – Walk to downtown, Vibrant Arena, restaurants & more • 🎮 Retro Vibe – Vintage decor + full-size Pac-Man machine • 🔒 Peaceful & Safe – Next to police station & city hall • 🔥 Outdoor Space – Private deck, fire pit, grill & Bluetooth lantern

Top guest favorite
The kitchen features white cabinetry that complements the spacious layout. A marble countertop provides ample workspace, while modern appliances, including a microwave and refrigerator, are visible. A coffee station is organized on a shelf, and natural light enters through a window dressed in light fabric.
Home in Geneseo
4.98 out of 5 average rating, 89 reviews

Home Away From Home

Forget your worries in this spacious and serene home conveniently located minutes away from downtown. 3 bedroom, 1 bath ranch features all the comforts of home. 3 queen beds and 1 queen pullout couch sleeps up to 8 people. Free wifi and smart TVs in all three bedrooms, living room and spare room, help you stay connected and entertained. A deck with patio furniture and a gas grill will help you enjoy the quiet backyard.

Top guest favorite
The exterior of the Wide River Winery is showcased, featuring a stone facade and welcoming signage. Colorful banners hang from the building, while outdoor seating with small tables and chairs is positioned along the sidewalk, inviting guests to enjoy the lively atmosphere.
Apartment in Le Claire
4.94 out of 5 average rating, 347 reviews

Wide River Winery Inn

Located in downtown historic LeClaire, a quaint but lively town on the Mississippi River. Two blocks from the American Pickers and a short walk to The Crane and Pelican and the La Ragazza Tuscan Kitchen & Bar. Up the street is Mississippi River Distilling Company and the delicious Brewery and next door is Cody Road Coffee. Guests are invited to sample our award winning wines.

Top guest favorite
An aerial view captures the unique farmhouse, bordered by expansive farmland. An in-ground pool and pool house are visible, along with ample green space surrounding the property. The landscape features a long road leading into the distance, accentuating the rural tranquility.
Home in Geneseo
4.98 out of 5 average rating, 53 reviews

Charming Geneseo Farmhouse

This Unique Farmhouse is located right on the edge of Geneseo offering a convenient commute to charming downtown as well as the best country views! The home offers an in ground pool and pool house, bonus room for movie nights. The bonus room also includes two twin size beds. It would be a wonderful quiet escape for a family or multiple families to enjoy each other's company.

Popular amenities for Geneseo vacation rentals

  1. Airbnb
  2. United States
  3. Illinois
  4. Henry County
  5. Geneseo