Vacation rentals in East Prairie

Glamping Double Domes on Private Lake & Hot Tub!

Adventure meets comfort at the Space Cowboy Lake Domes — the ultimate glamping experience where rustic frontier charm collides with sleek modern design. This unique double-dome retreat features a full kitchen, bathroom, and space for up to four guests across two connected domes — one with a cozy living area and sleeper sofa, the other with a private queen bedroom. Step outside to your expansive lakefront deck with a hot tub, fire pit, grill, outdoor shower, and private lake access and kayaks.

Twisted Sassafras Treehouse

A custom-built treehouse located on 10 acres with a water view that you can take in from the hot tub on the deck! It is nestled high in the trees and is the perfect romantic getaway for two! Feel like you are away from it all without being away from it all! This treehouse is located on a county road just minutes from Cape Girardeau. Enjoy catch and release fishing on site, local wineries, shopping in historic downtown Cape Girardeau, local restaurants, gambling, historical sites & more!

Rivertown Getaway

Great location in the middle of town. Easy walk to the downtown area that offers great history on area with a museum & historic one room schoolhouse, take a walk along the beautiful Mississippi River, check out Veterans Park, etc., so much do to and see! This home can sleep 4 comfortably and accommodate 2 more guest with a blowup air mattress that is on site. Inside you will find new appliances, bedding, and linens. The outside is a work in progress! No smoking or pets allowed.

Under the Stars - Farmhouse

Enjoy the tranquility of this modern farmhouse charmer! Custom built minutes from downtown Cape. Relax outside around the fire pit, roast marshmallows and watch the sunset. Finish the night with a long soak in the hot tub. Start the morning on the front porch rocking chairs and take in a sunrise. Open concept, fully equipped kitchen, 3 Bd. including King master/full bath, 2 Queens with full guest bath. Near Trail of Tears and walking distance to classic dive bar/burger joint

The Roost - Pets friendly

Welcome to The Roost, a cozy, modern tiny home in rural western Kentucky. With two lofts, a bedroom, full kitchen, washer/dryer, and space to sleep five, it’s perfect for a peaceful getaway. The property is home to our 4 off leash dogs who will greet you upon arrival. We ask all other animals are dog friendly. Enjoy sunsets, stocked ponds, wildlife, outdoor dining, and a fire pit. Named after The Hickory Chicken—Southern slang for morel mushrooms—this hidden gem is worth the search

Pops Cabin

Conveniently located approx 5 miles west of Paris. Pops Cabin, is located on our small 16 acre (work in progress) hobby farm of goats, chickens, 2 farm friendly dogs and occasionally a cat or 2 can be observed. :) You get the cabin all to yourself and It comes with 3 bedrooms, 3.5 baths, full kitchen, a front porch to sit down and relax. Yard space available for children to play in. We are a working farm, pets are allowed under certain conditions, along with a 40 pet fee.

Modern Luxury Cabin, Fireplaces, Hot Tub Paducah

Shepherd’s Lantern Acres offers an unparalleled luxury retreat experience, featuring two cabins that seamlessly blend modern comfort with breathtaking natural beauty. Your cabin features unobstructed views of over 2 acres of seasonal wildflower meadows and pristine nature. Dogs are also welcome to enjoy their very own dog spa! With a beautiful master suite, well-appointed kitchen, and in unit laundry, we have ensured that all the comforts of home are at your fingertips.

Newly Renovated 3 Bedroom 2 Bath Home - Sleeps 9

Looking for a spacious and welcoming Airbnb in Sikeston? 🏡✨ This gorgeous, newly renovated 3 bedroom, 2 bathroom home is the ideal destination for unforgettable memories with your loved ones. The house sleeps up to 9 guests comfortably, making it perfect for families and groups. Conveniently located in a fantastic residential area, you're just moments away from local attractions, shopping, and dining spots.

Golconda Lockmaster Home #1

Beautifully restored homes take you back in time when men and women kept watch over the Ohio River’s Lock and Dam 51. The Golconda Lockmaster Homes are perfect for riverside relaxation or a homebase to take in the natural wonders and outdoor adventures waiting for you in beautiful southern Illinois. Houses can accomodate couples or large groups and overlook the scenic Ohio River.

Emma’s Cottage

Take it easy at this unique and tranquil getaway. Emma’s cottage is located in the historic north end of Sikeston, just minutes away from the local hospital and power plant, which makes it a perfect place for traveling professionals and people coming into town to visit friends and family. This cottage is 2 bedrooms, 1 bathroom, with a queen bed and a full bed.

The Peery House at Springhill Farms

The Peery House is our family home-place, built circa 1900, transformed into a quaint Airbnb. It is located on our farm, Springhill Family Farms in Western KY and is a great place for someone looking to get away from the busyness of life, looking for rest and relaxation or just looking for a unique, little farmhouse while passing through the area.

THE DREAMCATCHER

Beautiful brick home with lake view and access to Reelfoot Lake (no ramp), paved drive with ample parking for boat / trailer, back deck with table and chairs, open space kitchen and den, perfect for group fishing trip, hunting trip, or just sight seeing, (area known for its large population of eagles), quiet neighborhood, peaceful place to stay.