
Hotels in Central Business District
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Top-rated hotels in Central Business District
Guests agree: these hotels are highly rated for location, cleanliness, and more.

Near River Ridge Commerce Center + Dining & Gym
Skip the chain feel—this stay is all about ease, location, and unexpected perks. Just across the river from downtown Louisville, this pet-friendly hotel puts you close to the Big Four Bridge, Whiskey Row, and bourbon-fueled adventures. After a day exploring, refuel at the on-site bar, break a sweat in the 24/7 gym with Peloton bikes, or chill in your spacious room. Free parking, friendly staff, and thoughtful touches? It’s the Airbnb-friendly hotel experience you didn’t know you needed.

Stay at the Mod Pod!
The Mod Pod is a funky atomic space located in the historic district of downtown New Albany Indiana- located next to our sci fi diner Lady Tron’s. The Pod sleeps up to 4 guests with a queen loft bed, full sized pull out, twin sized roll away. Don’t let our vintage vibe fool you- we have all of the creatures comforts! High speed internet 85 inch google tv Ample device charging Kitchenette with fridge/freezer, microwave and coffee maker Walk in shower Bidet Hair dryer and iron

Discover Vibrant Culture In Downtown Louisville
Located in the heart of Downtown Louisville, Fairfield Inn and Suites Louisville Downtown puts you within walking distance of top attractions. Just a short drive away, you can experience the iconic Churchill Downs, home of the Kentucky Derby. Kickstart your day with our complimentary breakfast buffet, offering a selection of classic American favorites like bacon and eggs. After a busy day, unwind in our indoor pool or stay active in our 24-hour fitness center.

Southern Comfort In Downtown Louisville
Located in the heart of Downtown Louisville, Fairfield Inn and Suites Louisville Downtown puts you within walking distance of top attractions. Just a short drive away, you can experience the iconic Churchill Downs, home of the Kentucky Derby. Kickstart your day with our complimentary breakfast buffet, offering a selection of classic American favorites like bacon and eggs. After a busy day, unwind in our indoor pool or stay active in our 24-hour fitness center.

Walk to 4th Street Live | Free Hot Breakfast + Gym
Stay in the heart of downtown Louisville, just four blocks from the Medical Downtown District and within walking distance of local distilleries, museums, Fourth Street Live, and the Kentucky International Convention Center. This central location makes it easy to explore the city on foot, whether you’re here for business, events, or bourbon history. Guests enjoy free hot breakfast, complimentary WiFi, an indoor pool, a fitness center, and a lobby bar.

Experience True Southern Comfort | Free Breakfast
Enjoy Southern hospitality and a great location when you book SpringHill Suites Louisville Downtown. Our all-suite hotel just off I-65 puts you steps from the iconic Whiskey Row. A few blocks away you can tour the city’s famous bourbon distilleries, shop in the NuLu district, or explore waterfront attractions. In the morning, stretch out your muscles in the fitness center or indoor pool before heading to our free breakfast buffet.

Enjoy Southern Hospitality | Free Breakfast
Enjoy Southern hospitality and a great location when you book SpringHill Suites Louisville Downtown. Our all-suite hotel just off I-65 puts you steps from the iconic Whiskey Row. A few blocks away you can tour the city’s famous bourbon distilleries, shop in the NuLu district, or explore waterfront attractions. In the morning, stretch out your muscles in the fitness center or indoor pool before heading to our free breakfast buffet.

Across University of Louisville + Free Breakfast
Designed with extended-stay travelers in mind, Residence Inn Louisville East offers upscale, all-suite accommodations with the comfort and privacy of apartment-style living. Start your morning with a complimentary hot breakfast buffet, then energize with a workout at our nearby fitness center. Located directly across from the University of Louisville Shelby campus, our hotel is a convenient choice for campus visitors.

Deluxe King Room | Galt House West Tower
As Louisville’s only true waterfront hotel, The Galt House puts you in the heart of both Bourbon Row and the city’s cultural scene, with Riverfront views at every turn. The West Tower Deluxe King invites you to unwind with refined décor and a spacious layout—ideal for couples or solo visitors. Step outside for bourbon bars, museum galleries, or walks along the scenic riverwalk.

Galt House | Exec Suite 2 Queens | Pool | 2 Units
With the Ohio River as your backdrop, The Galt House delivers an immersive Louisville experience—close to museums, downtown shops, and spirited bourbon culture. The West Tower Suite offers two queen beds, a living space, and dramatic water views—ideal for families or friends sharing an unforgettable stay. Enjoy sweeping skyline reflections with your morning coffee in hand.

Hilo Hotel - Room 101
Hotel Hilo is a bold, boutique stay on the grounds of Louisville’s iconic ATOMIC Soundclub. Each of our 8 king-bed rooms blends retro-modern style with luxe touches and shared balcony or patio access. Designed for both hi-energy nights and lo-key recoveries, Hilo is your launchpad for vibing hard, resting well, and experiencing the best of the Highlands—day or night.

Galt House | 2BR King Suite | Scenic Waterview
As Louisville’s only riverfront hotel, The Galt House offers direct cultural access to Kentucky’s signature venues and history—all with sprawling views of Ohio. The 2‑Bedroom King Suite includes a king and additional sleeping, spacious living quarters, and sweeping vistas—ideal for restful stays. It’s your riverside haven, merging urban energy with tranquil design.
Popular amenities for Central Business District hotels
Family-friendly hotels

Wingate Louisville | 2 Queen Beds | Near I-64

2 Queen Beds | Wingate Louisville East Stay

King Room - 1 bed

La Quinta Louisville East | King | Near Downtown

King Room - 1 bed

1BR Suite | Wingate Louisville | Near SDF Airport

Wingate Louisville | Studio Suite | Indoor Pool

Deluxe King | Wingate Louisville | Free Breakfast
Hotels with a pool

Wingate Louisville | 1BR Suite | Close to Airport

Galt House | Executive 1BR King Suite | Lap Pool

2Q Beds | Wingate Louisville | Near Expo Center

Exec Suite 2 Queens | Galt House | Ohio Rv Front

Galt House | 1BR Suite 2 Queens | Water view

Deluxe 2 Queen | Galt House | Waterfront Hotel

Galt House | 1BR Suite 2 Queens | Pool | 2 Units

Galt House | 2BR King Suite | Lap Pool | 2 Units
Other hotel vacation rentals

Deluxe 2 Queen | Galt House | Pool | 2 Units

Galt House | 1BR Suite King | Pool | Water View

Exec Suite 2 Queens | Galt House | Pets | 2 Units

1 King Suite | Hawthorn Louisville | East End Stay

Galt House | Exec Suite 2 Queens | Walk to Museums

1BR Suite 2 Queens | Galt House | Pets | 2 Units

1BR Suite King | Galt House | Enjoy Waterviews

Galt House | Deluxe 2 Q West Tower | Near Museums
Quick stats about hotels in Central Business District

Total vacation rentals
Explore 30 vacation rentals in Central Business District

Nightly prices starting at
Central Business District vacation rentals start at G$23,000 GYD per night before taxes and fees

Verified guest reviews
Over 190 verified reviews to help you choose

Family-friendly vacation rentals
10 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 30 rentals that welcome pets

Vacation rentals with a pool
30 properties feature pools

Rentals with dedicated workspaces
30 properties have a dedicated workspace

Wi-Fi availability
30 of Central Business District vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Central Business District rentals

4.9 Average rating
Central Business District stays are highly rated by guests—averaging 4.9 out of 5!

Nearby attractions
Central Business District's top spots, include Fourth Street Live!, Louisville Slugger Museum & Factory, and Louisville Slugger Field
Destinations to explore
- Apartment rentals Downtown
- Rentals with a hot tub Downtown
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- Rentals with pools Downtown
- Rentals with an EV charger Downtown
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- House rentals Downtown
- Condo rentals Downtown
- Fitness-friendly rentals Downtown
- Rentals with a washer and dryer Downtown
- Rentals with a fire pit Downtown
- Rentals with a patio Downtown
- Waterfront rentals Downtown
- Pet-friendly rentals Downtown
- Loft rentals Downtown
- Rentals with breakfast Downtown
- Hotel rooms Louisville
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- Buffalo Trace Distillery
- Kentucky Derby Museum
- Churchill Downs
- Kentucky Exposition Center
- Kentucky Kingdom & Hurricane Bay
- Valhalla Golf Club
- Louisville Slugger Museum & Factory
- Muhammad Ali Center
- Angel's Envy Distillery
- Louisville Slugger Field
- Big Four Bridge
- Falls of the Ohio State Park
- Kentucky Science Center
- Waterfront Park
- James B Beam Distilling
- University of Louisville
- Evan Williams Bourbon Experience
- Kentucky International Convention Center
- Marengo Cave National Landmark
- L&N Federal Credit Union Stadium
- Cherokee Park
- Bardstown Bourbon Company
- Bernheim Arboretum and Research Forest
- Jefferson Memorial Forest




