
Hotels in Central Business District
Find and book unique hotels on Airbnb
Top-rated hotels in Central Business District
Guests agree: these hotels are highly rated for location, cleanliness, and more.

King Room - 1 bed
This Deluxe Room offers a nature view with 1 king bed. Features include TV with pay-per-view, coffee maker, hair dryer, alarm clock radio and private voice mail.<p><b>Hotel Description</b></p>At Caesars Southern Indiana, you can look forward to a casino, a nightclub, and concerts and live shows. Hit the jackpot at this hotel with amenities such as a casino VIP room, 1800 slot machines, and 100 casino gaming tables. Treat yourself to a deep-tissue massage, a body wrap, or a manicure/pedicure at t

Near River Ridge Commerce Center + Dining & Gym
Skip the chain feel—this stay is all about ease, location, and unexpected perks. Just across the river from downtown Louisville, this pet-friendly hotel puts you close to the Big Four Bridge, Whiskey Row, and bourbon-fueled adventures. After a day exploring, refuel at the on-site bar, break a sweat in the 24/7 gym with Peloton bikes, or chill in your spacious room. Free parking, friendly staff, and thoughtful touches? It’s the Airbnb-friendly hotel experience you didn’t know you needed.

Stay at the Mod Pod!
The Mod Pod is a funky atomic space located in the historic district of downtown New Albany Indiana- located next to our sci fi diner Lady Tron’s. The Pod sleeps up to 4 guests with a queen loft bed, full sized pull out, twin sized roll away. Don’t let our vintage vibe fool you- we have all of the creatures comforts! High speed internet 85 inch google tv Ample device charging Kitchenette with fridge/freezer, microwave and coffee maker Walk in shower Bidet Hair dryer and iron

Stay and Play at Caesars SI!
Caesars Southern Indiana is the Louisville, KY area's premier gaming and dining resort destination. During your visit, you might try the Beef Wellington at Gordon Ramsay Steak or you can schedule a full body massage at Indulge Spa. With a hot tub, pool and walking trail all just steps away from the hotel, there is plenty to do for a long weekend! The resort features the area's largest casino featuring classic table games, a sportsbook and a broad array of slot machines.

Discover Vibrant Culture In Downtown Louisville
Located in the heart of Downtown Louisville, Fairfield Inn and Suites Louisville Downtown puts you within walking distance of top attractions. Just a short drive away, you can experience the iconic Churchill Downs, home of the Kentucky Derby. Kickstart your day with our complimentary breakfast buffet, offering a selection of classic American favorites like bacon and eggs. After a busy day, unwind in our indoor pool or stay active in our 24-hour fitness center.

Southern Comfort In Downtown Louisville
Located in the heart of Downtown Louisville, Fairfield Inn and Suites Louisville Downtown puts you within walking distance of top attractions. Just a short drive away, you can experience the iconic Churchill Downs, home of the Kentucky Derby. Kickstart your day with our complimentary breakfast buffet, offering a selection of classic American favorites like bacon and eggs. After a busy day, unwind in our indoor pool or stay active in our 24-hour fitness center.

Walk to 4th Street Live | Free Hot Breakfast + Gym
Stay in the heart of downtown Louisville, just four blocks from the Medical Downtown District and within walking distance of local distilleries, museums, Fourth Street Live, and the Kentucky International Convention Center. This central location makes it easy to explore the city on foot, whether you’re here for business, events, or bourbon history. Guests enjoy free hot breakfast, complimentary WiFi, an indoor pool, a fitness center, and a lobby bar.

Experience True Southern Comfort | Free Breakfast
Enjoy Southern hospitality and a great location when you book SpringHill Suites Louisville Downtown. Our all-suite hotel just off I-65 puts you steps from the iconic Whiskey Row. A few blocks away you can tour the city’s famous bourbon distilleries, shop in the NuLu district, or explore waterfront attractions. In the morning, stretch out your muscles in the fitness center or indoor pool before heading to our free breakfast buffet.

Enjoy Southern Hospitality | Free Breakfast
Enjoy Southern hospitality and a great location when you book SpringHill Suites Louisville Downtown. Our all-suite hotel just off I-65 puts you steps from the iconic Whiskey Row. A few blocks away you can tour the city’s famous bourbon distilleries, shop in the NuLu district, or explore waterfront attractions. In the morning, stretch out your muscles in the fitness center or indoor pool before heading to our free breakfast buffet.

Across University of Louisville + Free Breakfast
Designed with extended-stay travelers in mind, Residence Inn Louisville East offers upscale, all-suite accommodations with the comfort and privacy of apartment-style living. Start your morning with a complimentary hot breakfast buffet, then energize with a workout at our nearby fitness center. Located directly across from the University of Louisville Shelby campus, our hotel is a convenient choice for campus visitors.

Exec Suite 2 Queens | Galt House | Ohio Rv Front
With the Ohio River as your backdrop, The Galt House delivers an immersive Louisville experience—close to museums, downtown shops, and spirited bourbon culture. The West Tower Suite offers two queen beds, a living space, and dramatic water views—ideal for families or friends sharing an unforgettable stay. Enjoy sweeping skyline reflections with your morning coffee in hand.

Hilo Hotel - Room 101
Hotel Hilo is a bold, boutique stay on the grounds of Louisville’s iconic ATOMIC Soundclub. Each of our 8 king-bed rooms blends retro-modern style with luxe touches and shared balcony or patio access. Designed for both hi-energy nights and lo-key recoveries, Hilo is your launchpad for vibing hard, resting well, and experiencing the best of the Highlands—day or night.
Popular amenities for Central Business District hotels
Family-friendly hotels

Deluxe King | Galt House | Near Louisville Spots

Galt House | Exec Suite 2 Queens | Walk to Museums

Galt House | Deluxe 2 Q West Tower | Near Museums

Galt House | Dlx 2 Queen | Rooftop Pool | 2 Units

Executive 1BR King Suite | Galt House East Tower

Galt House | Executive 1BR King Suite | Lap Pool

Deluxe 2 Queen | Galt House | Waterfront Hotel

Wingate Louisville| Deluxe 2Q Beds| Pets Allowed
Hotels with a pool

Deluxe King Room | Galt House West Tower

Wingate Louisville | Deluxe Queen | Comp Breakfast

Deluxe 2Q Beds| Wingate Louisville| Pet Friendly

Dlx 2 Queen | Galt House | Steps to Waterfront Pk

Hawthorn Louisville | 2 Queen Suite | Pet-Friendly

Galt House | 1BR Suite 2 Queens | Water view

Galt House | Exec Suite 2 Queens | Pool | 2 Units

Galt House | 2BR King Suite | Lap Pool | 2 Units
Other hotel vacation rentals

Dlx 2 Queen | Galt House | Pets Welcome | 2 Units

Galt House | 2BR Water View Suite | Pool | 2 units

Galt House | 1BR Suite King | Pool | Water View

1BR Suite 2 Queens | Galt House | Pets | 2 Units

1BR Suite King | Galt House | Enjoy Waterviews

1BR Suite | Wingate Louisville | Near SDF Airport

Deluxe Queen | Wingate Louisville | Free Breakfast

LaQuinta Louisville East | Queen | Near Churchill
Quick stats about hotels in Central Business District

Total vacation rentals
Explore 30 vacation rentals in Central Business District

Nightly prices starting at
Central Business District vacation rentals start at G$23,025 GYD per night before taxes and fees

Verified guest reviews
Over 190 verified reviews to help you choose

Family-friendly vacation rentals
10 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 30 rentals that welcome pets

Vacation rentals with a pool
30 properties feature pools

Rentals with dedicated workspaces
30 properties have a dedicated workspace

Wi-Fi availability
30 of Central Business District vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Central Business District rentals

4.9 Average rating
Central Business District stays are highly rated by guests—averaging 4.9 out of 5!

Nearby attractions
Central Business District's top spots, include Fourth Street Live!, Louisville Slugger Museum & Factory, and Louisville Slugger Field
Destinations to explore
- Rentals with breakfast Downtown
- Apartment rentals Downtown
- Rentals with a hot tub Downtown
- Rentals with an accessible height toilet Downtown
- Rentals with outdoor seating Downtown
- Loft rentals Downtown
- Family-friendly rentals Downtown
- House rentals Downtown
- Condo rentals Downtown
- Fitness-friendly rentals Downtown
- Rentals with a washer and dryer Downtown
- Rentals with an EV charger Downtown
- Pet-friendly rentals Downtown
- Rentals with a fire pit Downtown
- Rentals with a patio Downtown
- Waterfront rentals Downtown
- Rentals with pools Downtown
- Hotel rooms Louisville
- Hotel rooms Jefferson County
- Hotel rooms Kentucky
- Hotel rooms United States
- Buffalo Trace Distillery
- Kentucky Derby Museum
- Churchill Downs
- Kentucky Exposition Center
- Kentucky Kingdom & Hurricane Bay
- Valhalla Golf Club
- Louisville Slugger Museum & Factory
- Muhammad Ali Center
- Angel's Envy Distillery
- Louisville Slugger Field
- Big Four Bridge
- Falls of the Ohio State Park
- Kentucky Science Center
- Waterfront Park
- James B Beam Distilling
- University of Louisville
- Frazier History Museum
- Evan Williams Bourbon Experience
- Kentucky International Convention Center
- Marengo Cave National Landmark
- L&N Federal Credit Union Stadium
- Cherokee Park
- Bardstown Bourbon Company
- Bernheim Arboretum and Research Forest




