
Hotels in Central Business District
Find and book unique hotels on Airbnb
Top-rated hotels in Central Business District
Guests agree: these hotels are highly rated for location, cleanliness, and more.

King Room - 1 bed
This Deluxe Room offers a nature view with 1 king bed. Features include TV with pay-per-view, coffee maker, hair dryer, alarm clock radio and private voice mail.<p><b>Hotel Description</b></p>At Caesars Southern Indiana, you can look forward to a casino, a nightclub, and concerts and live shows. Hit the jackpot at this hotel with amenities such as a casino VIP room, 1800 slot machines, and 100 casino gaming tables. Treat yourself to a deep-tissue massage, a body wrap, or a manicure/pedicure at t

King Room - 1 bed
This Non-Smoking Deluxe Room offers 1 king bed. Features include TV with pay-per-view, coffee maker, hair dryer, alarm clock radio and private voice mail.<p><b>Hotel Description</b></p>At Caesars Southern Indiana, you can look forward to a casino, a nightclub, and concerts and live shows. Hit the jackpot at this hotel with amenities such as a casino VIP room, 1800 slot machines, and 100 casino gaming tables. Treat yourself to a deep-tissue massage, a body wrap, or a manicure/pedicure at the onsi

Two Queen Room - 2 beds
This Deluxe Room offers a nature view with 2 queen beds. Features include TV with pay-per-view, coffee maker, hair dryer, alarm clock radio and private voice mail.<p><b>Hotel Description</b></p>At Caesars Southern Indiana, you can look forward to a casino, a nightclub, and concerts and live shows. Hit the jackpot at this hotel with amenities such as a casino VIP room, 1800 slot machines, and 100 casino gaming tables. Treat yourself to a deep-tissue massage, a body wrap, or a manicure/pedicure at

Two Queen Room - 2 beds
This Non-Smoking Deluxe Room offers 2 queen beds. Features include TV with pay-per-view, coffee maker, hair dryer, alarm clock radio and private voice mail.<p><b>Ho*Description</b></p>At Caesars Southern Indiana, you can look forward to a casino, a nightclub, and concerts and live shows. Hit the jackpot at this ho*with amenities such as a casino VIP room, 1800 slot machines, and 100 casino gaming tables. Treat yourself to a deep-tissue massage, a body wrap, or a manicure/pedicure at the onsite s

Near Downtown Louisville + On-Site Dining & Gym
Skip the chain feel—this stay is all about ease, location, and unexpected perks. Just across the river from downtown Louisville, this pet-friendly hotel puts you close to the Big Four Bridge, Whiskey Row, and bourbon-fueled adventures. After a day exploring, refuel at the on-site bar, break a sweat in the 24/7 gym with Peloton bikes, or chill in your spacious room. Free parking, friendly staff, and thoughtful touches? It’s the Airbnb-friendly hotel experience you didn’t know you needed.

Near River Ridge Commerce Center + Dining & Gym
Skip the chain feel—this stay is all about ease, location, and unexpected perks. Just across the river from downtown Louisville, this pet-friendly hotel puts you close to the Big Four Bridge, Whiskey Row, and bourbon-fueled adventures. After a day exploring, refuel at the on-site bar, break a sweat in the 24/7 gym with Peloton bikes, or chill in your spacious room. Free parking, friendly staff, and thoughtful touches? It’s the Airbnb-friendly hotel experience you didn’t know you needed.

Stay at the Mod Pod!
The Mod Pod is a funky atomic space located in the historic district of downtown New Albany Indiana- located next to our sci fi diner Lady Tron’s. The Pod sleeps up to 4 guests with a queen loft bed, full sized pull out, twin sized roll away. Don’t let our vintage vibe fool you- we have all of the creatures comforts! High speed internet 85 inch google tv Ample device charging Kitchenette with fridge/freezer, microwave and coffee maker Walk in shower Bidet Hair dryer and iron

Stay and Play at Caesars SI!
Caesars Southern Indiana is the Louisville, KY area's premier gaming and dining resort destination. During your visit, you might try the Beef Wellington at Gordon Ramsay Steak or you can schedule a full body massage at Indulge Spa. With a hot tub, pool and walking trail all just steps away from the hotel, there is plenty to do for a long weekend! The resort features the area's largest casino featuring classic table games, a sportsbook and a broad array of slot machines.

Discover Vibrant Culture In Downtown Louisville
Located in the heart of Downtown Louisville, Fairfield Inn and Suites Louisville Downtown puts you within walking distance of top attractions. Just a short drive away, you can experience the iconic Churchill Downs, home of the Kentucky Derby. Kickstart your day with our complimentary breakfast buffet, offering a selection of classic American favorites like bacon and eggs. After a busy day, unwind in our indoor pool or stay active in our 24-hour fitness center.

Southern Comfort In Downtown Louisville
Located in the heart of Downtown Louisville, Fairfield Inn and Suites Louisville Downtown puts you within walking distance of top attractions. Just a short drive away, you can experience the iconic Churchill Downs, home of the Kentucky Derby. Kickstart your day with our complimentary breakfast buffet, offering a selection of classic American favorites like bacon and eggs. After a busy day, unwind in our indoor pool or stay active in our 24-hour fitness center.

Experience True Southern Comfort | Free Breakfast
Enjoy Southern hospitality and a great location when you book SpringHill Suites Louisville Downtown. Our all-suite hotel just off I-65 puts you steps from the iconic Whiskey Row. A few blocks away you can tour the city’s famous bourbon distilleries, shop in the NuLu district, or explore waterfront attractions. In the morning, stretch out your muscles in the fitness center or indoor pool before heading to our free breakfast buffet.

Enjoy Southern Hospitality | Free Breakfast
Enjoy Southern hospitality and a great location when you book SpringHill Suites Louisville Downtown. Our all-suite hotel just off I-65 puts you steps from the iconic Whiskey Row. A few blocks away you can tour the city’s famous bourbon distilleries, shop in the NuLu district, or explore waterfront attractions. In the morning, stretch out your muscles in the fitness center or indoor pool before heading to our free breakfast buffet.
Popular amenities for Central Business District hotels
Family-friendly hotels

Across University of Louisville + Free Breakfast

Experience True Southern Comfort | Free Breakfast

Hotel Hilo - Room 101

King Room - 1 bed

Enjoy Southern Hospitality | Free Breakfast

Stay at the Mod Pod!

Discover Vibrant Culture In Downtown Louisville

Convenient Stay Minutes from Downtown & Attraction
Hotels with a pool

Across University of Louisville + Free Breakfast

Experience True Southern Comfort | Free Breakfast

King Room - 1 bed

King Room - 1 bed

Enjoy Southern Hospitality | Free Breakfast

Discover Vibrant Culture In Downtown Louisville

Prime Location Near Louisville Attraction - 2 Unit

Convenient Stay Minutes from Downtown & Attraction
Other hotel vacation rentals

Across University of Louisville + Free Breakfast

Experience True Southern Comfort | Free Breakfast

Near Downtown Louisville + On-Site Dining & Gym

Hotel Hilo - Room 101

King Room - 1 bed

Enjoy Southern Hospitality | Free Breakfast

Stay at the Mod Pod!

Discover Vibrant Culture In Downtown Louisville
Quick stats about hotels in Central Business District

Total vacation rentals
Explore 40 vacation rentals in Central Business District

Nightly prices starting at
Central Business District vacation rentals start at G$43,928 GYD per night before taxes and fees

Verified guest reviews
Over 130 verified reviews to help you choose

Family-friendly vacation rentals
10 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 30 rentals that welcome pets

Vacation rentals with a pool
30 properties feature pools

Rentals with dedicated workspaces
40 properties have a dedicated workspace

Wi-Fi availability
40 of Central Business District vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Central Business District rentals

4.7 Average rating
Central Business District stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Central Business District's top spots, include Fourth Street Live!, Louisville Slugger Museum & Factory, and Louisville Slugger Field
Destinations to explore
- Rentals with a fire pit Downtown
- Rentals with a patio Downtown
- Waterfront rentals Downtown
- Rentals with an EV charger Downtown
- Loft rentals Downtown
- Condo rentals Downtown
- Fitness-friendly rentals Downtown
- Rentals with a washer and dryer Downtown
- Apartment rentals Downtown
- Rentals with a hot tub Downtown
- Rentals with an accessible height toilet Downtown
- House rentals Downtown
- Rentals with breakfast Downtown
- Family-friendly rentals Downtown
- Rentals with outdoor seating Downtown
- Pet-friendly rentals Downtown
- Rentals with pools Downtown
- Hotel rooms Louisville
- Hotel rooms Kentucky
- Hotel rooms United States
- Buffalo Trace Distillery
- Kentucky Kingdom & Hurricane Bay
- Kentucky Derby Museum
- Valhalla Golf Club
- Angel's Envy Distillery
- Muhammad Ali Center
- Charlestown State Park
- Heritage Hill Golf Club
- Louisville Slugger Museum & Factory
- Louisville Slugger Field
- Big Four Bridge
- Turtle Run Winery
- Kentucky Science Center
- Falls of the Ohio State Park
- Waterfront Park
- River Run Family Water Park
- Hurstbourne Country Club
- Frazier History Museum
- Big Spring Country Club
- Evan Williams Bourbon Experience
- Rising Sons Home Farm Winery
- Bruners Farm and Winery
- Best Vineyards
- Lovers Leap Vineyards and Winer



