
House vacation rentals in Central Business District
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Top-rated house rentals in Central Business District
Guests agree: these houses are highly rated for location, cleanliness, and more.

Charming Highlands Home | Walk to Everything
Tucked along a quiet, tree-lined street in Louisvilleās Original Highlands neighborhood, youāll find a cozy, private retreat filled with character and unique decor. Featuring a large master bedroom with king Sleep Number bed, a spacious living/dining room area, 2 full bathrooms, and a cozy full sized guest room. Walk to the best restaurants, boutiques, and coffee shops. Explore the nearby parks or unwind in your peaceful, historic hideaway. 1 mile from NULU 2 from downtown 5 from the Downs

Walking Bridge, Putt Putt House
NEW LISTING: Welcome to our walking bridge home on Pearl St. We have a hot tub, putt putt, and all the fun you can think of in one home. Steps away from restaurants, shopping, and bars, as well as the walking bridge to Louisville. This home is closer to the fun in Louisville than most neighborhoods in Louisville itself. Go out or stay in, you're guaranteed to have a great time in this newly renovated gem. We have high quality mattresses, and smart TV's in both bedrooms and the living room.

Awesome Louisville/Nulu Getaway!
Whether you want to taste the bourbon, watch the horses, enjoy a concert at the Yum Center, or watch the Cards, this home is ideally located in NULU situated between downtown and the Bardstown Rd area. The back yard is fenced in with a well-maintained hot tub and tons of seating. Itās a Louisville oasis! Upstairs 1 king and 2 downstairs queen beds are spacious and extremely comfortable. The kitchen and living room are open and perfect for entertaining family and friends! Welcome to Louisville!

Hot Property! Early Bird Discounts for Derby!
Shotgun Rye is ready to host your stay in Louisville! Located close to everything cool in Germantown and Highlands area! People visit for Bourbon Tours, Ky Derby, Conventions, Expo Ctr, UL graduations and sporting events, live music and so much more! Completely remodeled with all the modern conveniences & a comfortable, casual touch. But with so much to see and do in Louisville youāll load up your itinerary with unforgettable experiences. Great location walk to bars, restaurants and shopping!

"Blue Grass" Pool Table Retreat - Plush Comfort
The perfect getaway to luxuriate in the center of Louisville! Boasting 11-foot tall ceilings, 75" televisions, and a spacious downstairs floor plan that includes a pool table, living room (with velvet sofas), and an open-air basement rec room with spiral staircase and fur bean bags. We decorated our home to provide as much comfort & entertainment as possible: super-cushy king-size memory-foam beds, vast porch space (with grill), and eclectic art to feed your eyes & mind. We hope you enjoy it!

Highlands Bishop Cottage-Walkable
Walkable Highlands Cottage in the Irish Hills neighborhood. Newly renovated with charm! Close to NULU (.5 mi), Butchertown (.6 mi), downtown (1 mi). Just 4 mi to the Yum Center, 5 mi to the Expo Center, 5.2 mi to Churchhill Downs, and 5.7 mi to the airport. Walkable to breweries, restaurants, parks and Cave hill Cemetery. You can even view the bridge over Ohio River from the end of the street. 1 on property small parking spot off alleyway with additional street parking on side streets

Butchertown & NuLu's Shantyboathouse
Welcome to the Shantyboathouse! Recognized as a truly unique property, it has twice been featured in the Courier-Journal and was honored with a historical plaque by the Louisville Landmarks Commission in 2019. According to a 1976 newspaper article, a local legend recounts that the house floated up the river during the 1937 flood, and was later set on a foundationāearning it the enduring nickname, "the shanty boat." This rich history adds to the property's distinctive character and charm.

Quiet Neighborhood Home With Outstanding Location
Situated on a quiet hilltop neighborhood in Clifton Heights, this is the perfect location for a professional or personal visit to Louisville and very animal friendly. It is within 10 minutes of Downtown, Waterfront Park, Nulu, Frankfort Avenue, the Highlands, the Convention Center, and just 15 minutes from historic Churchill Downs. These neighborhoods feature the best dining and entertainment in the city. Just a block away is the Mellwood Arts Center complex with shops and dining.

Cheerful, centrally located 2 bedroom shotgun home
This welcoming home is central to Louisville's most popular and lively neighborhoods, walking distance to many favorite spots. Natural light and unique art fill the home. There is a large deck that overlooks a beautiful cemetery behind the home, and is a perfect place enjoy morning coffee or sunset dinner. A coffee/tea bar is located in the fully equipped kitchen. Charging stations and white noise machines are found in both bedrooms. 2 workstations and a smart TV are also available.

Bourbon Trail Villa|King Suite|Fenced Backyard|BBQ
ā1900 sq-ft of modern living space ā1,000 sq-ft of fully fenced outdoor entertainment space āWeber grill, wood burning fire pit (wood included), huge swivel umbrella and outdoor dining for 6 āFully stocked Chef's kitchen āDry Bar āBig Screen TV's in every bedroom āNetflix Included āGames & books for kids and adults ā3rd story office space with twin bed and city skyline views āUrban bourbon trail āPet friendly! āMinutes from Churchill Downs, Distilleries, & KY Expo Center

Historic Parsonage in heart of NuLu action
Located in a lovingly renovated 1843 church, this small apartment boasts a queen-size bed, full bathroom, kitchenette with table for 3, and comfy sofa. You'll be in the middle of all Market Street has to offer ā steps from Rabbit Hole Distillery, Nouvelle Wine Bar, Garage Bar, and tons more. A 10-minute ride from the airport, you'll be half a mile from Slugger Field, and 1 mile from the YUM! and Convention Centers.

Convenient Walkable area | 1BR Highlands Stay!
Prime Location in Louisvilleās Most Walkable Area! Just 7 minutes to the KFC Yum! Center with dedicated parking and steps from hundreds of shops, bars, and restaurants. This comfortable, well-equipped home offers exceptional value for your stay. Enjoy: ā¢Easy self check-in with keypad ā¢Photo-guided check-in instructions ā¢Stocked kitchen for cooking ā¢Roku TV & free Wi-Fi
Popular amenities for Central Business District house rentals
House rentals with a pool

Louisville KY Home w/Hot Tub & Pool

The Getaway!

DERBY! The Ville Getaway! Centrally Located

Hot Tub | 5BR/5BA | King Beds | Expo

Peppermint Cottage Norton Commons w Breakfast

CIRCO LOCO - uNCommon Stay

East End Bungalow

Rock & Roll Riverhouse | Pool | Mins to Louisville
Weekly house rentals

2BR Home Near Zoo & Fairgrounds ā Family-Friendly!

Charming Shotgun Style Home, Great Location

Phoenix Hill House with Downtown Sunset Views

The Green House in Downtown

Charming Home, Centrally Located

Hot Tub | Fenced-in Yard | King Bed | Walk to Nulu

The House with the Orange Door

Historic Derby Carriage House
Private house rentals

Lay Low B-Side | NULU | 2BR | Balcony

The NULU Hideaway - downtown Louisville

Mint Julep Suite & Bourbon Room | Sleeps 2

Kentucky Derby Getaway, Pet-Friendly

Historic Gaffney House, Exclusive River Estate

Distillerās Reserve | 3-Story 1895 Bourbon Estate

Luxury 2BR ~ Heart of Clifton! Unit 1

Charming home in the heart of the city!
Quick stats about house rentals in Central Business District

Nightly prices starting at
Central Business District vacation rentals start at G$43,937Ā GYD per night before taxes and fees

Verified guest reviews
Over 270 verified reviews to help you choose

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Central Business District rentals

4.9 Average rating
Central Business District stays are highly rated by guestsāaveraging 4.9 out of 5!

Nearby attractions
Central Business District's top spots, include Fourth Street Live!, Louisville Slugger Museum & Factory, and Louisville Slugger Field
Destinations to explore
- Apartment rentalsĀ Downtown
- Rentals with a hot tubĀ Downtown
- Rentals with a fire pitĀ Downtown
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- Waterfront rentalsĀ Downtown
- Loft rentalsĀ Downtown
- Family-friendly rentalsĀ Downtown
- Rentals with outdoor seatingĀ Downtown
- Condo rentalsĀ Downtown
- Fitness-friendly rentalsĀ Downtown
- Rentals with a washer and dryerĀ Downtown
- Rentals with breakfastĀ Downtown
- Rentals with an accessible height toiletĀ Downtown
- Rentals with an EV chargerĀ Downtown
- Hotel roomsĀ Downtown
- Rentals with poolsĀ Downtown
- Pet-friendly rentalsĀ Downtown
- House rentalsĀ Louisville
- House rentalsĀ Jefferson County
- House rentalsĀ Kentucky
- House rentalsĀ United States
- Buffalo Trace Distillery
- Kentucky Derby Museum
- Kentucky Exposition Center
- Churchill Downs
- Kentucky Kingdom & Hurricane Bay
- Valhalla Golf Club
- Louisville Slugger Museum & Factory
- Angel's Envy Distillery
- Muhammad Ali Center
- Louisville Slugger Field
- Big Four Bridge
- Falls of the Ohio State Park
- Kentucky Science Center
- Waterfront Park
- University of Louisville
- James B Beam Distilling
- Evan Williams Bourbon Experience
- Kentucky International Convention Center
- L&N Federal Credit Union Stadium
- Jefferson Memorial Forest
- Marengo Cave National Landmark
- Bardstown Bourbon Company
- Cherokee Park
- Abraham Lincoln Birthplace National Historical Park




