House vacation rentals in Central Business District

Find and book unique houses on Airbnb

Top-rated house rentals in Central Business District

Guests agree: these houses are highly rated for location, cleanliness, and more.

%{current} / %{total}1 / 1
Top guest favorite
The living area features a gray sectional sofa adorned with yellow throw pillows, complemented by a modern coffee table. Natural light enters through large windows, enhancing the calming ambiance. A cozy armchair and standing lamp add to the seating options, while exposed brick adds character.
Home in Butchertown
4.96 out of 5 average rating, 228 reviews

Sip Bourbon on the Custom Brick Patio at Heartpine and Soul

Enjoy the preserved history of Heartpine and Soul-- a restored retreat originally built in 1888. Heartpine floors, exposed red brick, and decorative fireplaces are combined with thoughtful displays of old wallpaper and news clippings. STR929290 Cleanliness has always been a top priority for us, and with the COVID-19 pandemic, we are taking additional measures to provide a safe, sanitary space for you. Enjoy the preserved history of this updated shotgun home, with details such as restored heartpine floors, exposed brick, and even thoughtful displays of old wallpapers and news clippings . HeartPine and Soul comes complete with a fully-equipped kitchen, a small deck, and a custom-built brick patio. The house has two bedrooms, each with a queen bed. Two full baths. And a sofa that converts to a queen bed. The house can accommodate a maximum of six guests. We offer a pack-and-play for those toting a tot with them. Very residential and historic neighborhood. Street parking, but not congested. We consider no pets, no parties, no loud noises, and no smoking. We also kindly request no shoes be worn in the house. Guests may access all parts of the house except for the garage. Enjoy the deck and back patio, but please be respectful of our established and welcoming neighbors. If you’d like to celebrate or party, please take it to many of Louisville’s breweries, restaurants, and distilleries that are abound in Butchertown and neighboring areas such as NULU and downtown! I love Louisville, and so will you! Inside HeartPine and Soul, there is a detailed guidebook to the house, neighborhood, and city, containing helpful information and tidbits. As a hostess, I offer lots of privacy, yet if you need assistance or even some dining recommendations, I’m a quick phone call or text message away! I also love communicating thru the AirBnB app. This is a historic residential area around the corner from Flying Axes, Goodwood Taproom, Quills Coffee, Naïve, and future site of the Louisville City Football Club stadium. HeartPine and Soul is central to the Urban Bourbon Trail-- a quick ride to Angel's Envy, Rabbit Hole, and Michter's Fort Nelson Distillery. Convenient location to KFC Yum! Center. Six miles to Churchill downs. Street parking, but not congested. Guests may park in front of the house. If you don’t have a car during your stay, Lyft and Uber are abundant in the Butchertown neighborhood. There’s also a bikeshare station called LouVelo, so you may pedal across town. The closest station is the west Butchertown station at Main & Clay. Some of the original landscape paintings in the home are by Mike Stevens and are for sale. HeartPine and Soul is another quality remodel project by Living Spaces By Lyn.

Guest favorite
Home in Butchertown
4.84 out of 5 average rating, 247 reviews

NuLu & Angel’s Envy at Your Door| Great for Groups

This spacious, personality-filled home in the heart of downtown is the perfect base for bourbon trail weekends, weekday corporate stays,or family get-togethers. You can walk everywhere! With 3,000 sq ft of flexible space it's great for group connection; there's a private patio, plenty of gathering zones, comfy beds, a chef’s kitchen, and thoughtful touches that make your stay feel special. The home is soulful and full of character—ideal for groups who value comfort, style, and a great location.

Guest favorite
A welcoming exterior view of a stylish house features a covered front porch with seating and decorative elements. The spacious interior showcases a cozy living area with comfortable seating and art on the walls. A well-maintained outdoor space includes a putting green. Natural light brightens the rooms.
Home in Jeffersonville
4.99 out of 5 average rating, 123 reviews

Walking Bridge, Putt Putt House

NEW LISTING: Welcome to our walking bridge home on Pearl St. We have a hot tub, putt putt, and all the fun you can think of in one home. Steps away from restaurants, shopping, and bars, as well as the walking bridge to Louisville. This home is closer to the fun in Louisville than most neighborhoods in Louisville itself. Go out or stay in, you're guaranteed to have a great time in this newly renovated gem. We have high quality mattresses, and smart TV's in both bedrooms and the living room.

Top guest favorite
A spacious living area features a navy blue couch adorned with patterned pillows, accompanied by an ottoman. Light wood flooring flows throughout, leading to an open kitchen with stainless steel appliances and light-colored cabinetry. The area is brightened by recessed lighting and wall art.
Home in Louisville
4.95 out of 5 average rating, 209 reviews

Awesome Louisville/Nulu Getaway!

Whether you want to taste the bourbon, watch the horses, enjoy a concert at the Yum Center, or watch the Cards, this home is ideally located in NULU situated between downtown and the Bardstown Rd area. The back yard is fenced in with a well-maintained hot tub and tons of seating. It’s a Louisville oasis! Upstairs 1 king and 2 downstairs queen beds are spacious and extremely comfortable. The kitchen and living room are open and perfect for entertaining family and friends! Welcome to Louisville!

Guest favorite
A modern kitchen is showcased, featuring sleek cabinetry and an island with seating for four. Three pendant lights hang above, providing warm illumination. The stainless steel appliances include a refrigerator and a microwave. Natural light enters through large windows, adding brightness to the space.
Home in Germantown
4.92 out of 5 average rating, 208 reviews

Hot Property! Early Bird Discounts for Derby!

Shotgun Rye is ready to host your stay in Louisville! Located close to everything cool in Germantown and Highlands area! People visit for Bourbon Tours, Ky Derby, Conventions, Expo Ctr, UL graduations and sporting events, live music and so much more! Completely remodeled with all the modern conveniences & a comfortable, casual touch. But with so much to see and do in Louisville you’ll load up your itinerary with unforgettable experiences. Great location walk to bars, restaurants and shopping!

Guest favorite
A modern living area features a soft pink sofa embellished with decorative floral pillows. A glass coffee table is centered on a multi-colored area rug. Light enters from large windows outfitted with sheer curtains, creating a bright and inviting space. Artwork adorns the nearby walls.
Home in Louisville
4.94 out of 5 average rating, 206 reviews

Highlands Bishop Cottage-Walkable

Walkable Highlands Cottage in the Irish Hills neighborhood. Newly renovated with charm! Close to NULU (.5 mi), Butchertown (.6 mi), downtown (1 mi). Just 4 mi to the Yum Center, 5 mi to the Expo Center, 5.2 mi to Churchhill Downs, and 5.7 mi to the airport. Walkable to breweries, restaurants, parks and Cave hill Cemetery. You can even view the bridge over Ohio River from the end of the street. 1 on property small parking spot off alleyway with additional street parking on side streets

Top guest favorite
The inviting living area features exposed brick walls and a high ceiling. A warm-toned sofa with decorative pillows is positioned on a geometric area rug, complemented by a rustic coffee table. A staircase leads to an upper loft area, with ambient lighting provided by a stylish chandelier.
Home in Louisville
4.96 out of 5 average rating, 166 reviews

The Burb Inn - Nulu & Downtown *w/Firepit*

The Burb Inn is a hip place to stay in the Phoenix Hill/NULU district of Louisville. Easy access to top rated restaurants, bars, and attractions. Great place to host a group of friends, family or smaller bachelor party. Includes private parking, yard & fire pit. Upon entering there is a living area perfect for entertaining with 16’ ceiling & sleeping loft above the kitchen area. Upstairs has two bedrooms with queen beds each with private half bath. There is a separate private shower room.

Top guest favorite
The exterior of the Shantyboathouse is presented, featuring a two-story blue structure with white trim and a welcoming patio area below. The backyard offers comfortable seating and a grill, while greenery lines the edges. The upper deck is accessible, providing additional outdoor space for relaxation.
Home in Butchertown
5 out of 5 average rating, 226 reviews

Butchertown & NuLu's Shantyboathouse

Welcome to the Shantyboathouse! Recognized as a truly unique property, it has twice been featured in the Courier-Journal and was honored with a historical plaque by the Louisville Landmarks Commission in 2019. According to a 1976 newspaper article, a local legend recounts that the house floated up the river during the 1937 flood, and was later set on a foundation—earning it the enduring nickname, "the shanty boat." This rich history adds to the property's distinctive character and charm.

Guest favorite
A bedroom features a spacious bed with a striped coverlet and a decorative pillow. Large windows allow natural light, and a rustic sliding door complements the dark green walls. A circular mirror above a work desk adds a functional touch to the inviting space.
Home in Smoketown Jackson
4.94 out of 5 average rating, 108 reviews

Heart of Louisville 3BR Getaway

Welcome to your home in the heart of Louisville! This 3 bedroom, 2 bath space provides ample room for you and your guests. Nestled in the middle of NULU, the Highlands, and Downtown, you'll have central access to everything the city has to offer. Whether you're visiting Churchill Downs, exploring the Bourbon Trail, grabbing flights at Whiskey Row, or attending a summer concert, this is the perfect base for your adventures. Relax and create lasting memories in My Old Kentucky Home.

Top guest favorite
A backyard is displayed, featuring a hot tub and a gas fire pit surrounded by four outdoor chairs. Patio heaters provide warmth, and the space is framed by a fence. The modern home is visible in the background, illuminated by evening light.
Home in Louisville
4.96 out of 5 average rating, 291 reviews

Hot Tub | Fenced-in Yard | King Bed | Walk to Nulu

5-minute walk to the heart of NuLu and close to the Bourbon Trail Backyard retreat with colorful flowers, a hot tub, fire pit, and outdoor dining area Chef-ready kitchen featuring an Instant Pot, rice cooker, toaster, and just about every coffee maker imaginable Full cable TV plus streaming access to Netflix, Disney+, Hulu, and HBO Max Nintendo Switch with multiple games for all ages Board game collection for fun nights in 15 minutes to Churchill Downs, UofL, and the airport

Top guest favorite
The exterior of the house, featuring a welcoming front porch, is surrounded by lush greenery. A staircase leads up to the entrance, framed by neatly maintained shrubs. The architectural design reflects a blend of classic and modern elements, complemented by a bright sky and scattered clouds.
Home in Louisville
4.91 out of 5 average rating, 114 reviews

MARYLAND HOUSE - Highlands luxury, WALK TO ALL

Superhost Property! Very safe location, Front porch w/swing 1st-floor master with ensuite bath w/Jacuzzi 3 Bedrooms, 2 Full Baths Street Parking for 2 vehicles Well stocked, full kitchen Koi pond off Master Bedrooms Tasteful arts and crafts design/decor On-site washer and dryer 4.9 Miles to Expo Center/Airport Churchill Downs 4.2 Miles to Downtown & Distilleries Less than 1 mile to Cherokee Park No locals No Events Only registered guests, Please.

Top guest favorite
A spacious living area is equipped with a large sectional sofa and a wooden coffee table, providing a comfortable gathering space. The modern kitchen features stainless steel appliances and dark cabinetry, while an open layout invites natural light from the adjacent windows.
Home in Germantown
4.95 out of 5 average rating, 165 reviews

The Caldwell Highlands/Germantown

Welcome to The Caldwell, a Germantown/Highland area home that includes three bedrooms, one and half bathrooms and sleeps up to five people. The home is within walking distance of several restaurants, bars, retail and vintage stores, and entertainment venues including the Germantown Gables, Logan Street Market and Old Forester’s Paristown Hall. The home features a covered deck, a fenced-in yard as well as home gym.

Popular amenities for Central Business District house rentals

Quick stats about house rentals in Central Business District

  • Nightly prices starting at

    Central Business District vacation rentals start at G$43,921 GYD per night before taxes and fees

  • Verified guest reviews

    Over 270 verified reviews to help you choose

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Central Business District rentals

  • 4.9 Average rating

    Central Business District stays are highly rated by guests—averaging 4.9 out of 5!

  • Nearby attractions

    Central Business District's top spots, include Fourth Street Live!, Louisville Slugger Museum & Factory, and Louisville Slugger Field

  1. Airbnb
  2. United States
  3. Kentucky
  4. Jefferson County
  5. Louisville
  6. Downtown
  7. House rentals