Family-friendly vacation rentals in DeWitt

Anne's Place

Our place is conveniently located in a quiet and safe neighborhood just off the interstate - 10 minutes from Syracuse University, LeMoyne College, hospitals and downtown. It is just minutes away from Starbucks, Panera's, Wegmans and numerous other restaurants and shopping facilities. It is also very close to the Erie Canal trail (1/2 mile) for walking, jogging or biking. We have chosen to go with a farmhouse theme with our decor. We live next door and you will enjoy total privacy when you stay.

Strathmore Contemporary Home

Completely remodeled 1920’s home in the Strathmore neighborhood of Syracuse. The property is centrally located near a beautiful park with biking and running trails. Located minutes to downtown, close to Community General and Upstate Hospital’s, and ten minutes to Syracuse University. The owners live in the other half of the home, enjoy hosting guests, and meticulously maintaining the property. The house is a side-by-side duplex with 1700 sq ft. on each side with separate front/back entrances.

Carriage house studio/book nook

SYR second floor studio and first floor book nook in detached carriage house next to owner occupied home. Private. Modern. Authentic. Near SU, downtown, and hospitals. House backs up to beautiful Elmwood park and our family garden. Perfect for 1 or 2 (potentially 3). Great for coffee, book, and nature lovers. Stairwell to apartment is narrow and could be a challenge for some. Access to fenced private family garden if you like. We are often around and outside but the apt is very private.

SyracuseSpot-PoolTable/Traeger /Firepit /Cornhole

Do you want to spread out, BBQ, have a fire and other fun things to do? This is your SYRACUSE SPOT! The 1920's home (remodeled in 2025) is less than 10 minutes to most of the Syracuse venues, hospitals, and parks. Bring your family and friends (furry included) to our home and make it your own. Enjoy the fast Wi -Fi, full coffee/tea bar, snacks, and 4K TV's in every room! Our goal is to bring a high value option that provides a fun space unique to the market. We welcome you to CUSE!

Gracious 1920s Georgian close to hosp & colleges

The whole group will enjoy easy access to everything from this spacious, centrally located home. Close to SU, LeMoyne, ESF, St Joseph’s hospital, Crouse & Upstate. Enjoy the large kitchen and separate dining room, and relax in the living room. You can look forward to a great nights sleep in our 2- king beds in our master suites, or a full in the guest room. If you don’t require full use of the house, please let us know and we can adjust the cleaning fee prior to your booking.

Chic Comfort • Two Bedroom Apt

Relax in this bright, thoughtfully designed apartment featuring a cozy living area, stylish decor, and a dedicated workspace. Enjoy natural light and modern comfort. Minutes from downtown, Syracuse University, Destiny USA, and top hospitals. Features two bedrooms with comfy queen beds & a fully equipped kitchen. Perfect for business travelers, University visits, or weekend getaways. Just 12 minutes from the airport, with easy access to dining, shopping and entertainment.

Enormous Convenient Home in Clean, Quiet Syracuse

Welcome to your perfect getaway in Syracuse, New York! Our expansive home offers a blend of comfort, and charm, making it an ideal choice for both short and long-term stays. Whether you're in town for a family vacation, a work trip, or an extended stay, this home caters to all your needs. Its convenient location provides easy access to Syracuse's local attractions, dining, and entertainment. Experience comfort like never before in a place that feels like home!

Affordable private basement apartment

My place is 10 min from Syracuse University, Upstate University hospital, Crouse Irving hospital, 5 min from LeMoyne College, 8 min from downtown Syracuse and St. Joeseph's Health hospital, 16 min from Green Lakes State Park... You’ll love my place because of the quaintness, the quiet and the proximity to what Syracuse has to offer. My place is good for couples, small families, solo adventurers, people with animals, and business travelers.

★ Quiet Gem minutes to SU, Downtown & Westcott! ★

Centrally located and cozy gem in the quiet, safe, and friendly Meadowbrook neighborhood. Minutes away from the center of Syracuse University, the Carrier Dome, Le Moyne College, and shopping centers. Just 4 minutes to the Westcott Theater by car and a pocket of unique restaurants. My home features everything you need for a comfortable stay in Syracuse. I'd love to have you come to enjoy the beautiful area!

Darling Cottage Suite Near Green Lakes & Trails

In-law suite with private entrance in wooded setting near Green Lakes State Park (1 mile away). Includes downstairs kitchen and upstairs bedroom suite with queen bed and claw foot tub with handheld shower (no standing shower). Twin air mattress available upon request. Guests enjoy access to 100+ acres of wooded trails, perfect for walking and mountain biking.

Renovated 1880’s Milk Barn

Experience a unique stay in our fully renovated, charming, and historic tiny home. Situated on 2.25 acres of tranquil land, you'll have the perfect blend of nature and convenience. Just 10 minutes from Green Lakes! A local Gem! 12 minutes to Destiny USA 10 minutes to downtown Syracuse 15 minutes to the SU Dome 17 minutes to the Lakeview Amphitheater.

Gardener's Cottage Close to Town

Kick off your shoes, brew a cup of tea, and relax in this lovely two bedroom cottage. Nestled in a quiet residential neighborhood, it's close to everything in Syracuse yet provides a peaceful, comfortable retreat to return to. Please note, the cottage is not suitable for children under 12 years of age. We do not allow pets. Thank you.