Vacation rentals in Clayton
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Quick stats about vacation rentals in Clayton
Total vacation rentals
Explore 40 vacation rentals in Clayton
Nightly prices starting at
Clayton vacation rentals start at G$12,555 GYD per night before taxes and fees
Verified guest reviews
Over 1,300 verified reviews to help you choose
Family-friendly vacation rentals
10 properties offer extra space & kid-friendly amenities
Pet-friendly vacation rentals
Find 10 rentals that welcome pets
Rentals with dedicated workspaces
20 properties have a dedicated workspace
Wi-Fi availability
30 of Clayton vacation rentals include wi-fi access
Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Clayton rentals
4.7 Average rating
Clayton stays receive an average rating of 4.7 out of 5 from guests
Top-rated vacation rentals in Clayton
Guests agree: these stays are highly rated for location, cleanliness, and more.
Large U. City Apt 4 BR, 2 Bath, Pool, near Wash U.
Deb and I welcome you to our newly renovated charming U City first floor apartment - your home base to explore the best of St. Louis neighborhoods. Close to Wash U & Metro link. Minutes from Forest Park, Zoo, Loop, and Clayton - just 12 min to downtown. Choose from dozens of nearby restaurants or stay home and cook in the spacious kitchen. Lounge by the large pool open June through September. In unit washer/dryer. Park with playground and public tennis/pickleball courts across the street.
Modern Condo on Delmar Loop; Central to Everything
This absolutely stunning condo in the Delmar Loop are has everything you could need. Located only 100 feet from Delmar and a short walk to WashU Campus or Forest Park. Metro Link is only a 10 minute walk away. Perfect for visits to WashU for college visits and graduations! The Pageant and Delmar Hall making this the perfect condo to stay in to see your favorite band! One off-street parking spot in a gated parking lot. The entire condo community is gated & equipped with video surveillance.
3-bdrm apt near Pageant, Wash U, Forest Park, Loop
Three bdrm, top floor apt. with private entrance in our home. Roomy, comfy, well-furnished with everything you need. Walk to Pageant, Delmar Hall, WashU, Blueberry Hill, Salt&Smoke, MagicMiniGolf. CVS, grocery, restaurants and shops on the Delmar Loop. Or stroll our leafy streets to Forest Park, built 1904 for a World’s Fair, now a first-class museum, zoo, golf course, boat rental. Easy access via metro train or Uber/Lyft to airport, baseball, hockey, live music clubs, City Museum, the Arch.
Tranquil three-bedroom home in central St. Louis
Welcome to Spa 7748! Relax and enjoy the quiet, tranquil space we have to offer you. Three bedrooms, two full baths, laundry room, work out area, media/office area, fully equipped chef’s kitchen, two fireplaces, covered patio, outdoor fire pit, driveway parking, and street parking. Centrally located in University City, which is just minutes from the downtown Clayton business/entertainment district, Washington University, Fontbonne University Downtown STL, Central West End, The Grove, Dogtown.
Luxurious Downtown Loft Steps From City Museum
You and your group will adore this stunning & spacious downtown 4th floor loft located right on the popular Washington Avenue in St. Louis! You will be in a prime location and can walk to so many restaurants, cafes, shops, bars, and even attractions like The City Museum and Union Station! Cozy up on the plush couch, turn on the gas fireplace, and enjoy a gorgeous sunset view right from the living room! With a spa tub, luxury bedding/towels/bath robes, and furnishings…you won’t want to leave!
Cozy Cottage in a Quiet City Neighborhood!
Please inquire for longer stay rates. This 650sq.ft quaint cottage has EVERYTHING! Centrally located this sought after historical neighborhood, DOGTOWN!, is just minutes from Forest Park and a short drive to all of STL's BEST ATTRACTIONS! This charmer has all the amenities you could hope for @ your HOME away from home! 2 Bedrooms with a Queen Bed in each, 3 Smart TV's, a backyard patio, KEYLESS Self Entry, fully equppied kitchen with SS appliances, MAIN FLOOR LAUNDRY and fully UPDATED BATH!
Great Fam Friendly Home w/ Lrg Deck & Yard
**FAMILY FRIENDLY** (See details for the items avail for families) This 2 bedroom home has everything you need for a relaxing trip! Fully updated with stylish and comfortable furniture and decor. Fully equipped kitchen and an amazing backyard/deck. Quiet street by one of the best Mexican restaurants in St. Louis - Hacienda - (can walk 2 min there) Close to everything! 13 minutes to the St. Louis Zoo 10 minutes to The Magic House 15 minutes to Busch Stadium & Union Station
Hidden Gem in Central West End + Gated Parking
Wake up to sunny mornings with coffee and Netflix to then go enjoy the vibrant energy of the St. Louis. Walk through beautiful Forest Park to enjoy museums, lakes, and tree lined paths. Discover why this city is one of the Midwest’s hidden food gems — with amazing BBQ, Italian restaurants, breweries, and local favorites all within easy reach. Whether you're here to unwind or discover the city, this cozy retreat is your perfect home base. Book now—your adventure awaits :)
Stylish Family Home with a Fully Fenced Yard
Escape to our stylish & eclectic St. Louis home on a quiet street, perfect for family fun! This vibrant space comfortably fits 5 guests with 2 queen bedrooms, a sunroom with a pullout sofa, and a basement den for movie nights. Enjoy a fully equipped kitchen and easy access to all of St. Louis's top attractions. Whether you are headed to the game downtown or having dinner on The Hill, you will not be far away. Your perfect city adventure base awaits!
Blair's House - Long Stays Welcome - 7 min to BJC
Welcome to Blair's House on Ahern Ave. 3 Bedrooms and 3 Full Bathrooms Long Stays Welcome! Book for 30 days and SAVE!!!! Relax in the living room or cozy up in bed and watch a movie. TV's in every room! Coffee with three options; Drip, Keurig & Press Kitchen is fully stocked with all the essentials for casual cooking or thanksgiving dinner. 60-1 Arcade Game & Poker Table Check out our profile for more listings. Over 30 available.
Weaver Guest House
This charming, light-filled cottage feels like its own private hideaway, yet it's close to everything St. Louis has to offer. Tucked between trees in a quiet Maplewood neighborhood, it's a 15-minute walk to the MetroLink and a 10-minute drive to Washington University, Webster University, Fontbonne University, Forest Park, and Clayton. Business travelers and families alike will appreciate the washer/dryer, fast WIFI and cable TV.
Apartment in University City
Relax in this cozy 2nd story queen bedroom apartment, located just 5 minutes from Clayton, the Delmar Loop, and Washington University. This beautiful all-brick home sits in a quiet neighborhood. Enjoy free street parking and a smooth, self-check-in process. The secluded area offers easy access to great restaurants, grocery stores, and more. A peaceful retreat with everything you need nearby for a comfortable stay.
Popular amenities for Clayton vacation rentals
Other great vacation rentals in Clayton
Cozy City Craftsman
*New - 2Bedroom 1Bath Fully renovated
Modern & Central Abode * STL Zoo & Forest Park *
Spacious 3 bedroom / 1 bath located in Demun!
Hill Retreat in Prime Location
Elegant 2 bedroom unit with patio
Studio in Clayton, MO
Beautiful Historic Home near Wash U & U City
When is the best time to visit Clayton?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$22,599 GYD | G$23,018 GYD | G$26,157 GYD | G$26,575 GYD | G$29,295 GYD | G$27,621 GYD | G$27,412 GYD | G$27,203 GYD | G$27,203 GYD | G$26,157 GYD | G$30,342 GYD | G$26,157 GYD |
| Avg. temp | 0°C | 3°C | 8°C | 14°C | 20°C | 25°C | 27°C | 26°C | 22°C | 15°C | 8°C | 3°C |
Frequently Asked Questions
What are the best places to stay in Clayton?
Visitors frequently choose accommodations in the downtown Clayton area for walkable access to dining, shops, and cultural venues. Neighborhoods surrounding Shaw Park are also suggested for a quieter stay with access to outdoor spaces.
What are the best things to do in Clayton with kids?
Children enjoy playgrounds and pools at Shaw Park, story times at the public library, and hands-on workshops at art centers. Family-friendly festivals and community events throughout the year create ways for kids to explore and play.
What are some of the best things to do in Clayton?
Explore public art, dine at locally owned restaurants, and unwind in green spaces like Shaw Park and Oak Knoll Park. Galleries, seasonal markets, and pop-up events contribute to a lively calendar throughout the year.
How is the weather in Clayton?
Clayton experiences cold winters around 24–40°F (-5–5°C), while summers are warm with highs near 90°F (32°C). Spring and autumn are milder and wetter, bringing comfortable conditions and seasonal color.
When is the best time to visit Clayton?
Late spring and early fall are often recommended for visits to Clayton, when temperatures are milder, and parks showcase vibrant seasonal colors. Local festivals and outdoor dining also create a welcoming atmosphere during these months.
What are the best places to visit in Clayton?
Clayton has the Saint Louis Art Museum nearby, public art installations, and the community-focused Shaw Park. Visitors also explore local galleries, farmer’s markets, and tree-lined streets with historic architecture.
What are some hiking trails in Clayton?
Explore local parks in Clayton, such as Shaw Park, which has walking paths and green spaces suitable for gentle walks. For more wooded trails, the area around Oak Knoll Park is often suggested for a peaceful stroll. Nearby nature preserves and community gardens also invite outdoor exploration.
What are some family activities we can do in Clayton?
Families often enjoy the playgrounds and splash pads at Shaw Park, interactive exhibits at local galleries, and picnics in Oak Knoll Park. Seasonal community events and farmers markets create opportunities for families to connect and explore together.
What are some of the best day trip ideas from Clayton?
Many visitors explore St. Louis attractions such as the Gateway Arch, Missouri Botanical Garden, and Forest Park. For a change of pace, local wineries, river towns, or wildlife areas around the region invite relaxation and discovery.
Are there any pet friendly accommodations available in Clayton?
Many accommodations in Clayton welcome pets, especially in areas close to parks and green spaces. Consider stays near Shaw Park or in residential neighborhoods for more convenient pet-friendly options.
What are some local tips for visiting Clayton?
On weekends, many locals enjoy farmers markets and food trucks around downtown. Consider exploring public art on foot and pack layers, as the weather can change quickly in spring and autumn.
What is Clayton known for?
Clayton is recognized as a center for business, art, and dining, with tree-lined neighborhoods and widely admired public parks. Its cultural calendar and commitment to public art draw residents and visitors alike.
What are the best hidden gems to explore in Clayton?
Art-filled alleyways, quiet gardens at Oak Knoll Park, and small galleries around downtown are often mentioned as lesser-known spots. Local cafés and specialty shops tucked along tree-lined streets reveal creative touches from the community.
What are the best foods to try in Clayton?
Clayton is known for classic Midwestern favorites, barbecue, toasted ravioli, and gooey butter cake. Local cafés and bakeries often highlight regionally inspired pastries and fresh seasonal ingredients.
What should I bring for a trip to Clayton?
Bring comfortable walking shoes for exploring parks, casual clothing, and a light jacket, especially if visiting in spring or autumn. Summers can be warm, so sun protection and refillable water bottles come in handy, while winter travelers may want a warm coat and gloves.
What is the nightlife in Clayton like?
Clayton has a relaxed nightlife scene with cocktail lounges, wine bars, and restaurants offering live music. Many people also gather at casual neighborhoods spots for late-night meals and conversation.
What are the most popular events or festivals in Clayton?
Clayton hosts the Saint Louis Art Fair each September, one of the region’s most popular art festivals, plus seasonal events like summer concert series and holiday markets. Local parks also host family-focused gatherings and community celebrations.
Are there family friendly vacation rentals in Clayton?
Clayton has a variety of family-friendly vacation rentals available, especially in neighborhoods near local parks or downtown. Rentals often include kitchens and flexible living spaces suitable for group stays.
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- Busch Stadium
- Central West End
- Six Flags St. Louis
- Saint Louis Zoo
- Enterprise Center
- The Dome at America's Center
- St. Louis Aquarium at Union Station
- Gateway Arch
- City Museum
- Missouri Botanical Garden
- Washington University in St Louis
- Hidden Valley Ski Resort
- Forest Park
- Gateway Arch National Park
- Castlewood State Park
- Meramec Caverns
- Saint Louis University
- The Pageant
- Saint Louis Science Center
- Saint Louis Art Museum
- Cathedral Basilica of Saint Louis
- Soulard Farmers Market
- Westport Plaza
- Missouri History Museum