Vacation rentals in Clarksdale

A cozy corner seating area features a bright blue upholstered couch with decorative pillows. A low, circular wooden table is positioned centrally. A green door with a unique design adds character to the wall, while framed artwork and photographs adorn the surrounding space.

4.93 out of 5 average rating, 176 reviews

The Squeeze Box-"get your Blues on"

LOCATION-LOCATION-LOCATION The Squeeze Box is a spacious, airy 425 sq. ft. private vacation apartment, located in the heart of Historic Downtown Clarksdale, Mississippi. The newly constructed apartment is located on the ground floor of the former Clarksdale Telegraph Building (Circa 1897) @ the corner of Second & Delta in the Historic Blues District. Located across the street from the Hambone Art Gallery, and the “Rock & Blues Museum”, this is the best location in town. Gift shops around the corner. Restaurants including The Stone Pony, Yazoo Pass, Levon's Bar and Grill, and Grandma's House of Pancakes are literally all within 300 feet of our front door. CatHead Blues, Lambfish Gallery, and Hambone Gallery are all on our block. The Delta Blues Museum is a short walk, and Ground Zero Blues Club, New Roxy and Red’s Lounge are an easy 5-minute stroll. The Squeeze Box is the best location in Clarksdale for walkable access to restaurants, music venues, museums,bars, clubs,art galleries,shopping on Delta,convenience store,and the wine & spirits store. No need to drive once you check in.....park your car, and party to your heart's content. And The Squeeze Box is located on the ground floor, so there are no stairways to climb or drag your bags up. And we have a covered veranda out front with seating for six,so you can enjoy the fresh air, while enjoying a nice beverage. Although there is no smoking allowed in the apartment, the veranda is just outside your door. Available by the night,weekends, and weekly. Inquire about longer stays.

4.96 out of 5 average rating, 47 reviews

A cozy sitting area is presented with comfortable seating and a television. Light-colored walls are complemented by wood accents. A small table is situated near the doorway, while a refrigerator is visible in the background. A colorful rug enriches the space.

Casa particular in Lyon

Safest Place in Clarksdale Come Visit With Us

The barn house apartment is cozy and comfortable with 2 spacious bedrooms, 1 and a half baths, laundry room., full kitchen and sitting area. Close and easy access to downtown Clarksdale and Helena, AR for blues fans. 5 miles from Ground Zero Blues Club and downtown Clarksdale 5 miles from historic Hwy 49 & Hwy 61 Crossroads 20 miles from Moon Lake 26 miles from Isle of Capri Casino 4.4 miles from Northwest Regional Medical Center 20 miles from O'keef WMA 75 miles from Memphis Intl Airport

A single-story home presents a classic brick façade with a prominent garage. The well-kept yard features neatly trimmed shrubs and lush greenery. The driveway leads to the garage, providing ample parking space. Large windows allow natural light to enter the living spaces.

Home in Clarksdale

4.73 out of 5 average rating, 161 reviews

Down Home Southern Charmer

This is the home that my sister and I grew up in with our parents and younger brother, who have passed on. We love our home, and are now opening it up to guests from anywhere in the world who want a comfortable place to stay while visiting the Mississippi Delta. Available to our guests are a centrally heated and cooled home with two bedrooms, a living/dining room, a family room with TV and Internet, two bathrooms, a kitchen, washer and dryer, and a garage. And, we just put in new floors!

5 out of 5 average rating, 29 reviews

The exterior of the home features a vibrant yellow front door, flanked by decorative plants. The brick facade and large windows provide a welcoming entrance. A well-maintained lawn surrounds the front, enhancing the inviting appearance of the property.

Home in Clarksdale

Delta Dream Retreat (Entire Home)

Relax with the whole family at this peaceful place to stay. we have put our heart and soul into renovating this entire home with all new appliances , bedding, furniture, mattresses, etc. It Is very modern and comfortable for families. It incl wi-fi, usb and multi movie channels every room, games, coffee, water, tea, and complimentary snacks. Only one camera[ring door bell] at the front door. Great neighbors and less than 2m from downtown Blues venues, Historical Crossroads, & eateries.

4.91 out of 5 average rating, 315 reviews

A charming cottage is set amidst lush greenery, featuring a unique gabled roof and a welcoming front porch with rocking chairs. A circular table with metal chairs is positioned on a pebbled area, surrounded by trees, providing a tranquil outdoor space.

Cottage in Clarksdale

Sunflower Cottage on the River

Only a mile from historic home of the blues, Clarksdale in a gated community. The cottage sits on the banks of the Sunflower River with beautiful views of rustic woods. Out your window you might see deer, fox & other wildlife. Take a walk along the riverbank. You’ll enjoy relaxing in the comfy beds, ,enjoy privacy, the piano , & closeness to all the blues music venues. It has two fire pits, an outside grill & full kitchen. Great for couples, adventurers, business travelers , musicians ,

4.83 out of 5 average rating, 159 reviews

A charming blue cottage features a gabled roof and a white front door framed by two light fixtures. Two vintage chairs are positioned on the grassy area in front, surrounded by mature trees that provide some shade.

Cottage in Clarksdale

The Gallery at Chateau Debris

Welcome to The Gallery! This one-bedroom cottage sits behind the main house. It has recently been renovated, but is decorated with vintage furnishings for personality. The cottage is equipped with a full kitchen, bedroom, bathroom, washer and dryer, & Roku TV. Your stay will be unique, as the decor has been selected from my collector's lair, and the best part is - it's all for sale! The Gallery is a live-in collectibles showroom so, contrary to the saying - you CAN take it with you!

4.73 out of 5 average rating, 15 reviews

The living area features two comfortable sofas arranged around a glass coffee table. Natural light pours in through large windows adorned with light, flowing curtains. A television rests on a media console, complementing the welcoming atmosphere.

Loft in Clarksdale

Sunflower Lofts D

Welcome to The Sunflower Lofts! These modern, fully furnished apartment style accommodations are located in the heart of downtown Clarksdale. With a coffee shop just a few doors down and all the best restaurants & music venues within walking distance, you won't even need to get in the car until you leave! We accept long and short-term guests, so stay with us for one night or a few weeks! No pets. No smoking. Quiet hours begin at 10:00 pm. We do not accept local reservations.

4.95 out of 5 average rating, 20 reviews

A spacious bedroom is equipped with two queen-sized beds, each dressed in soft blue bedding. A cozy couch is positioned nearby, and decorative wall art adorns the grey walls. Natural light filters through window treatments, enhancing the inviting atmosphere.

Home in Lambert

Southern Charm

Relax with the whole family at this peaceful place to stay. You'll have three bedrooms and four queen sized beds for your enjoyment. A very spacious living/dining room area for the whole family to sit and chat. There is also two full-sized bathrooms. Also included is a screened in outdoor porch with plenty of seating. There is onsite laundry accommodations and a complete kitchen with all the ammenities.

4.94 out of 5 average rating, 427 reviews

The brick exterior of Blues Hound Flat is characterized by large glass block windows and a centrally positioned red door. Horizontal blinds cover the windows, providing a sense of privacy while allowing light to filter through. A small air conditioning unit is visible above the door.

Loft in Clarksdale

Blues Hound Flat

Blues Hound Flat sits quietly across from the historic Greyhound bus station in the center of downtown Clarksdale. Step outside, and you're in the heart of the Delta Blues, surrounded by local eateries, shops, bars, and music venues! The air itself is heavy with the traditions of the Delta. This loft-style flat features all the basic amenities one could want and solitude when needed.

The living area features exposed brick walls and large windows, providing natural light. A cozy couch is complemented by two side tables and lamps on either side. A decorative coffee table enhances the inviting atmosphere of the space.

4.95 out of 5 average rating, 22 reviews

High Cotton Condo Unit D

High Cotton Condo Unit D is centrally located in heart of downtown Clarksdale with 2 bedroom, 2 baths, and a foldout couch in the living room. This unit is updated and fresh with a large living room, a modern kitchen, and great retractable windows that look out onto Delta Avenue below! Condo D has all the modern luxuries you need to make your trip to Clarksdale complete!

4.94 out of 5 average rating, 16 reviews

The exterior of a single-story house is highlighted by a well-maintained lawn, framed by trees. Light-colored siding and brown shutters complement the entrance, which features a white door and a welcoming open porch area.

Home in Marvell

Tranquil home away from home

Relax with the whole family at this peaceful place to stay. The Parsonage accommodates everyone! 3 bedroom, 2 bath home in the center of town immersing you in a little slice of home. The house has two separate living areas, an eat-in bar, dining room and a fenced in backyard and storage building available if needed during your visit or hunting trips.

5 out of 5 average rating, 17 reviews

A light blue bungalow with multiple sections is set among lush greenery. The home features a raised porch with steps leading up and a railing that enhances accessibility. Tall trees provide shade to the surrounding grassy area.

Home in Lyon

Guitar Frenchie’s Corner!

Take it easy in the heart of the Delta! This bungalow/ shotgun house is the perfect getaway for Blues lovers who want all the fun that Clarksdale’s home of the Blues has to offer and the quaint and quiet of old town Lyon, birthplace of Son House! Located 5min from the heart of Downtown Clarksdale MS. Come see us & hear great Live music!

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Other great vacation rentals in Clarksdale

Top guest favorite

A hallway features vibrant artwork depicting musicians on the walls, complemented by a cozy seating arrangement. A medium-sized area rug adds warmth to the wooden flooring, while natural light filters in from the windows at either end, creating an open and welcoming ambiance.

Shared room in Clarksdale

5 out of 5 average rating, 55 reviews

Hostel Downtown Prime Location - Bed in 8 Bed Dorm

Private room in Clarksdale

4.92 out of 5 average rating, 25 reviews

Yellow House - Upstairs Eyrie Suite

4.93 out of 5 average rating, 44 reviews

The exterior of a stately brick house is captured, showcasing large windows and well-defined architectural details. A welcoming entrance is framed by a porch, surrounded by manicured grass and trees. The structure's design reflects a mix of traditional and eclectic styles, adding to its character.

Home in Clarksdale

Chateau Debris

4.86 out of 5 average rating, 7 reviews

An open-plan living area features a comfortable sofa, accompanied by two blue armchairs. A wooden dining table is positioned centrally, with modern kitchen appliances visible in white cabinetry. Large windows allow natural light to fill the space, highlighting the metal ceiling design.

Home in Dundee

*Brand New Construction* Moon Lake View Cabin

4.8 out of 5 average rating, 10 reviews

A modern kitchen area features sleek black cabinetry and a wooden countertop with bar seating for three. Stainless steel appliances, including a refrigerator and microwave, are present, along with essential kitchen tools and a coffee maker conveniently arranged.

Loft in Clarksdale

Sunflower Loft A

The exterior of the Hooker Hotel is featured prominently, displaying a bold sign. A variety of people are seated on the curb, enjoying the atmosphere. Nearby, an orange wall contrasts with the hotel's facade, while art displays are set up in front, showcasing local photography.

4.95 out of 5 average rating, 146 reviews

Hooker Hotel - Rated #1 "5 Star"

Guest suite in Clarksdale

An outdoor deck is furnished with comfortable seating, including a sectional sofa adorned with decorative pillows. A large umbrella provides shade over a circular dining table with swivel chairs. Lush greenery is visible in the background, enhancing the outdoor setting.

4.86 out of 5 average rating, 131 reviews

The Sunflower Penthouse on the River in Clarksdale

A vibrant building exterior features a large mural depicting musicians and guitars. The entrance to Delta Digs is marked by an arrow, drawing attention to its location amidst the colorful artwork. Windows along the facade showcase a lively atmosphere.