
Family-friendly vacation rentals in Cayce
Find and book unique family-friendly homes on Airbnb
Top-rated family-friendly rentals in Cayce
Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

Lucy’s Place
This 950 sq ft minimalist home is the perfect place to relax with family and friends. This West Columbia home is in a convenient spot for you to spread out and make yourself at home. The home is only 2 miles off of the interstate if you are just traveling through. You’ll be about 10 minutes from the University of South Carolina, Colonial Life Arena, the Statehouse, Riverbanks Zoo, Williams Brice Stadium, the Vista, The Columbia Riverwalk and many more local attractions if you are staying a while

Secure prime location close to USC and Downtown
Great location in the Shandon/downtown Area. Walking distance to 5points restaurants & bars. Secured building with cameras at all entrances and parking lot. Featuring Eat-in kitchen includes refrigerator, Stove/oven, microwave, Dishwasher. Spacious living room area, clean linens, Hotel style wall units for heat and air conditioning. TVs in living room and bedroom. Free Netflix. Coin operated laundry machines in each floor of the building. Located on 3rd floor, sorry no elevators in the building

The Blue Door Farmhouse | 2BR 1BA Near DT Cola
The Blue Door Farmhouse is an adorable house that has been given a complete makeover! Built over 100 years ago, this house was moved to it's current location in the 40s and has tons or character. With 2 bedrooms and 1 bath with a full-size pull-out sofa bed in the den, there is plenty of space and privacy at the Blue Door Farmhouse in the Earlewood Park Neighborhood of Columbia. Off-street parking and a private fenced-in backyard are all for your use during your retreat to our wonderful city.

Lovely 2BD 2BA condo overlooking Rosewood Drive
Perched above Rosewood Dr, with views of the bustling street below, this expansive 2-bed, 2-bath condo offers a prime location in Columbia, SC. This beautifully furnished condo promises a luxurious stay. Located near Starbucks, Alloy Personal Training, Dental Care of Rosewood, and Masa Mexican Street Food, you're steps away from dining and entertainment options. Ideal for those seeking comfort and convenience in the heart of Columbia. Secure your stay today and elevate your urban experience!

4 miles USC/Ft Jackson -The Nest
Welcome to "The Nest"! From convenience to comfort this gem is a perfect retreat! Our home is centrally located just 4 miles from Ft Jackson, 3.5 mile from USC, & 5 mile from Colonial Center/Vista/business district. Come home to relax and enjoy all the amenities from cozy couches to 3 private bedrooms equipped w/ flat screen TV's. Or gather for a family meal, enjoy our outside deck/ grill & lg fenced yard or play at the park. Clean & comfortable -our nest is the perfect place to rest!

Columbia’s Best Airbnb
Take it easy at this unique and tranquil getaway. Our Airbnbs are the nicest in each town. From our known luxurious mattresses to the best kept secret… 3D luxury digital Massage chairs relax you from any stressful situation. See why we are ambassador Airbnb host. Stay at this location and you are 5 to 10 minutes to the USC baseball, basketball and Football. Campus is same. Airport is 4 miles. Great kid activity at EdAdventure kid museum. I 26, I-77 and downtown Columbia are minutes away.

✷ Dazzling Downtown Deco ✷ 2 BD 1 BA Home
This fancy little 1940's house in Historic Keenan Terrace (Minutes from Downtown Columbia) has so much class and character! It has been completely renovated and has all new everything - from a super stylish fully stocked kitchen to the show stopping funky bathroom complete with deep soaking tub. This house has been updated with care, every - super inviting, totally stylish, and ultra comfy digs - we are sure it will more than meet your needs during your stay - you're going to love it!

Golden Reflections Getaway
Welcome to the Golden Reflection Getaway—a spacious, stylish retreat perfect for families and groups. Enjoy this 2,600+ sq. ft. spacious family area with three luxury themed bedrooms upstairs and extra sleeping options with a full bathroom on the main level. Tucked away in a peaceful neighborhood, just 7 minutes from the vibrant heart of Downtown Columbia and 18 minutes from Fort Jackson. Relax, recharge, and make lasting memories in this thoughtfully designed and comfortable home.

High-styled Historic - (UofSC)
Built in 1959, this home has been completely remodeled with modern luxuries, and original hardwood floors throughout still tell the tales of decades of love and history. The decor gives a nod to a New York City loft style space, with a blend of both clean modern lines and warm rustic finishes. 1.2 mi - Steel Hands Brewing 1.8 mi - University of South Carolina 2.2 mi - Riverbanks Zoo & Garden 3.6 mi - Williams Brice Stadium 4.9 mi - Columbia Metropolitan Airport

Lizzi & Scott’sTiny Guest House secluded USC-Vista
Welcome to our tiny guest cottage hidden in the heart of the city. It's within blocks of restaurants, coffee shops, an art movie house, and a lovely river walk. The Lace House/Governor’s Mansion, business district, MiLB & UofSC are a short walk or bike ride away. At the rear of our home, it’s private, secure & quiet. A partition & movable screen separate the bathroom area. There’s a smart tv, small fridge, microwave, coffeemaker & work-table.24 hr self check-in.

Beaufort Stateroom
Settle down and relax in this exceptionally clean one bedroom In-Law Suite. Featuring wood floors, kitchenette, spacious living room area, clean linens, supple furniture, walk-in closet, and cozy bedroom nook with a quality mattress to ensure you have a good night's rest. Your private space comes with an outside patio, all located in the historic Earlewood neighborhood with plenty of great restaurants and all of Columbia's downtown attractions only minutes away.

Little WeCo Cottage
Centrally located one bed one bath house. This 700 sqft house is perfect for a weekend getaway or a week working remote. Completely remodeled and ready for your next trip. Quiet street with only a couple of neighbors but still close to town. Within a 10 minute drive from the airport, downtown and 5-points - there really couldn't be a more prime location. Ft. Jackson is a quick 15 minute drive away too. Come stay at this cute cottage for your next trip to Cola.
Popular amenities for Cayce family-friendly rentals
Family-friendly home rentals with a hot tub

Panoramic Lakefront with Hot Tub

Skylight Spa Cottage - USC, FT. J, Williams-Brice

Rosewood Bungalow

Unit A: Private Jacuzzi Suite w/Laundry + Fridge

Cute & cozy cabin in Lexington, SC

Lazy Creek Cove Cottage w EV Plug!

The Farmhouse @ Goat Daddy's

Lakefront w pool, dock and pool table, sleeps12
Family- and pet-friendly home rentals

Cozy 3 BR Bungalow Located in Downtown Columbia

COLA Condo III 5pts &Downtown Columbia

Downtown Blue BoHo w/ outdoor spaces, grill & FP

Downtown Modern Industrial Oasis

Brand New Studio Guest House with Full Kitchen.

Brookhaven West near USC

Casa Torwood

Private Upstairs Duplex-Brookstone Retreat
Family-friendly home rentals with a pool

Spacious Getaway with Pool, Hot Tub, and Game Room

Lavish Home 4BR/3BA, King, Games, Grill, Pool!

University of South Carolina, William Bryce, SH

Saluda Retreat

Modern condo, closest to the University of SC

Cozy Home Away From Home

CB90 Condo: Pool, Arcade Games, Ft. Jackson, USC

Seminole Stroll • Pool • Fire Pit • Near USC & Zoo
Quick stats about vacation rentals that are family-friendly in Cayce

Total vacation rentals
Explore 250 vacation rentals in Cayce

Nightly prices starting at
Cayce vacation rentals start at G$8,368 GYD per night before taxes and fees

Verified guest reviews
Over 14,830 verified reviews to help you choose

Pet-friendly vacation rentals
Find 100 rentals that welcome pets

Vacation rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
150 properties have a dedicated workspace

Wi-Fi availability
250 of Cayce vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Cayce rentals

4.8 Average rating
Cayce stays are highly rated by guests—averaging 4.8 out of 5!
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- Family-friendly rentals Lexington County
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- Riverbanks Zoo and Garden
- University of South Carolina
- South Carolina State House
- Congaree National Park
- Williams Brice Stadium
- Columbia Museum of Art
- South Carolina State Museum
- West Columbia Riverwalk Park and Amphitheater
- Dreher Island State Park
- Saluda Shoals Park
- Colonial Life Arena
- Edventure
- Sesquicentennial State Park
- Columbia Metropolitan Convention Center
- Riverfront Park
- Soda City Market
- Frankie's Fun Park
- Segra Park
- Koger Center for the Arts
- Lake Murray Dam North Recreational Area





