
Family-friendly vacation rentals in Cayce
Find and book unique family-friendly homes on Airbnb
Quick stats about vacation rentals that are family-friendly in Cayce

Total vacation rentals
Explore 270 vacation rentals in Cayce

Nightly prices starting at
Cayce vacation rentals start at G$8,351 GYD per night before taxes and fees

Verified guest reviews
Over 16,390 verified reviews to help you choose

Pet-friendly vacation rentals
Find 110 rentals that welcome pets

Vacation rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
160 properties have a dedicated workspace

Wi-Fi availability
270 of Cayce vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Cayce rentals

4.8 Average rating
Cayce stays are highly rated by guests—averaging 4.8 out of 5!
Top-rated family-friendly rentals in Cayce
Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

Lucy’s Place
This 950 sq ft minimalist home is the perfect place to relax with family and friends. This West Columbia home is in a convenient spot for you to spread out and make yourself at home. The home is only 2 miles off of the interstate if you are just traveling through. You’ll be about 10 minutes from the University of South Carolina, Colonial Life Arena, the Statehouse, Riverbanks Zoo, Williams Brice Stadium, the Vista, The Columbia Riverwalk and many more local attractions if you are staying a while
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Your Serenity: Beautiful Sleep, Steps to Riverwalk
Beautiful home in prime location - walk to restaurants, brewpub & riverwalk > USC or Ft Jackson visiting family - we specialize in welcoming you! > Near Columbia's attractions - safely tucked away across the river > House, deck & location offer an unforgettable ambiance & memories for you & your loved ones >Minutes to Columbia Attractions >Massive 400 sq ft deck w/ festive lights wraps around a huge tree > King memory foam comfy bed > High-speed Wi-Fi & YouTube TV >Fully fenced private back yard
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Boho Chic WeCo Retreat | Walk to Dining & 75” TV
Looking for a stylish and clean place to stay near everything Columbia has to offer? You found it! Our brand new home is a 4 bedroom, 3 bath with king beds, a stocked kitchen, a 75” TV, and a fenced-in yard with patio seating. You are a quick drive to Williams-Brice Stadium, USC campus, Riverbanks Zoo, the State House, Congaree National Park & Sesquicentennial State Park. And you are a short walk to some of the best dining in Columbia like Savage Craft Ale Works, Black Rooster, and Café Strudel.
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The Carolina Cottage: Near Ft Jackson, Zoo & 5pts!
Enjoy true Southern hospitality and charm at this 3-bed, 2-bath Columbia home! Whether you’re here to visit family at Fort Jackson or friends at USC, this vacation rental has ALL the essentials you need for a relaxing stay. *Special rates also provided for Military Families waiting on housing. The space: Central Location| Easy Access to Downtown, Five Points & Public Transit (5-10 min) Fort Jackson: 15 Min. Zoo 10 Min MAIN FEATURES: 1 Smart TV ( Master bedroom), 1 TV w/ Roku-living room.
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Columbia’s Best Airbnb
Take it easy at this unique and tranquil getaway. Our Airbnbs are the nicest in each town. From our known luxurious mattresses to the best kept secret… 3D luxury digital Massage chairs relax you from any stressful situation. See why we are ambassador Airbnb host. Stay at this location and you are 5 to 10 minutes to the USC baseball, basketball and Football. Campus is same. Airport is 4 miles. Great kid activity at EdAdventure kid museum. I 26, I-77 and downtown Columbia are minutes away.
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Peaceful quarters close to downtown
Lovely quiet neighborhood with sidewalks. This is a furnished home with coffee makers , pots/pans, towels, bed linens ready for you to occupy and enjoy as your own home. It is located about 2 miles from Lexington medical center and about 6 miles to down town Columbia. Very safe neighborhood with great neighbors. Smart TVs in living room and all bedrooms. Weekly Trash service included . Central heating and air. Washer and dryer located in garage. Comfortable screened in porch to enjoy.
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Farmhouse at WeCo near DT, USC, Ft. Jackson! Pets.
Step into our historic pre-war farmhouse with cabin charm & modern spaces. Enjoy 2k sq ft, 4 br, and 2 bath on a peaceful, tree-lined property in a safe Columbia neighborhood. Centrally located for easy exploration, this unique home is thoughtfully set up for small to large groups seeking a memorable stay. You're only -3 min drive Riverbanks Botanical Gardens/ Zoo -6 min to Lexington Med Center -8 min to Downtown -10 min to USC (12 min William Bryce-Stadium) -20 min to Ft Jackson
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Golden Reflections Getaway
Welcome to the Golden Reflection Getaway—a spacious, stylish retreat perfect for families and groups. Enjoy this 2,600+ sq. ft. spacious family area with three luxury themed bedrooms upstairs and extra sleeping options with a full bathroom on the main level. Tucked away in a peaceful neighborhood, just 7 minutes from the vibrant heart of Downtown Columbia and 18 minutes from Fort Jackson. Relax, recharge, and make lasting memories in this thoughtfully designed and comfortable home.
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Elmwood Retreat for Remote Work & Family Fun
Come and enjoy your stay at Elmwood Retreat, a beautifully renovated 4 BR home in historic Elmwood Park. Built in 1905 and updated with modern comfort, it's perfect for remote work, family trips or extended stays. Enjoy high-seed Wi-Fi, a dedicated workspace, and a peaceful neighborhood. Steps from Main Street and the Vista and close to Riverwalks, museums, parks and Colonial Life Arena, this home offers charm, safety and convenience, for every guest to feel home.
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Lizzi & Scott’sTiny Guest House secluded USC-Vista
Welcome to our tiny guest cottage hidden in the heart of the city. It's within blocks of restaurants, coffee shops, an art movie house, and a lovely river walk. The Lace House/Governor’s Mansion, business district, MiLB & UofSC are a short walk or bike ride away. At the rear of our home, it’s private, secure & quiet. A partition & movable screen separate the bathroom area. There’s a smart tv, small fridge, microwave, coffeemaker & work-table.24 hr self check-in.
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Little WeCo Cottage
Centrally located one bed one bath house. This 700 sqft house is perfect for a weekend getaway or a week working remote. Completely remodeled and ready for your next trip. Quiet street with only a couple of neighbors but still close to town. Within a 10 minute drive from the airport, downtown and 5-points - there really couldn't be a more prime location. Ft. Jackson is a quick 15 minute drive away too. Come stay at this cute cottage for your next trip to Cola.
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Spacious Getaway with Pool, Hot Tub, and Game Room
Welcome to your perfect family retreat in West Columbia! This spacious 4-beroom, 3-bathroom home offers everything you need for a fun and relaxing stay. Dive into the private pool, unwind in the jacuzzi, or enjoy game nights with family and friends. Located minutes from the scenic Riverwalk Park and downtown Columbia, it's the idea base for exploring. Modern, cozy and full of entertainment. - Book your stay today.!
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Popular amenities for Cayce family-friendly rentals
Family-friendly home rentals with a hot tub

Luxury Treehouse in the heart of Columbia
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Lakefront w pool, perfect place for a small venue
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Panoramic Lakefront with Hot Tub
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Lazy Creek Cove Cottage w EV Plug!
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The Marigold- USC+Hot Tub+Fire Pit+Game Room+Grill
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Orange Pit | Luxe 3BR + 75" TV + Fire Pit Yard
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River & Rose Landing - Spa, Sauna, Karaoke Room
Indoor spacesFamilyHot tub

Palmetto Paradise* Pool & Epic Game Room Retreat!
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Family- and pet-friendly home rentals

Comfy 3BR House Near Zoo & I-26
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The White Rabbit House
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Lovely 2BR · Williams-Brice & Fort Jackson
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Beaufort Stateroom
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4 miles USC/Ft Jackson -The Nest
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Brookhaven West near USC
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Downtown Blue BoHo w/ outdoor spaces, grill & FP
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Spacious BoHo Bungalow in Cola
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Family-friendly home rentals with a pool

Lavish Home 4BR/3BA, King, Games, Grill, Pool!
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CB90 Condo: Pool, Arcade Games, Ft. Jackson, USC
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5 beds, full kitchen, saltwater pool & game room!
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Saluda Retreat
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Seminole Stroll • Pool, Fire Pit, Near USC & Zoo
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Modern condo, closest to the University of SC
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Devine Downtown Condo Near USC, Fort Jackson
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Cozy Home Away From Home
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- University of South Carolina
- Congaree National Park
- Riverbanks Zoo and Garden
- Williams Brice Stadium
- South Carolina State House
- South Carolina State Museum
- West Columbia Riverwalk Park and Amphitheater
- Columbia Museum of Art
- Colonial Life Arena
- Saluda Shoals Park
- Sesquicentennial State Park
- Columbia Metropolitan Convention Center
- Dreher Island State Park
- Edventure
- Riverfront Park
- Soda City Market
- Koger Center for the Arts
- Lake Murray Dam North Recreational Area
- Segra Park
- Frankie's Fun Park





