Vacation rentals in Wapello

Lake House • Kayaking Fishing, Sunrises, Bonfires

Little House on the Lake is a peaceful, cozy lake home retreat surrounded by nature and quiet beauty. Wake up to striking sunrises over the lake through large picture windows, and settle into slow, unhurried days. Spend your days relaxing on the deck, kayaking, paddleboarding, or simply enjoying the quiet rhythm of the water and woods. Unwind or gather around the fire pit and enjoy our timeless lake house getaway feel -perfect for families, couples, and anyone looking to slow down and reconnect.

Waterfront Cabin on Lake Odessa

Take it easy at this unique and tranquil getaway on Lake Odessa in Wapello, Iowa. Enjoy beautiful views and access to fishing, boating, and other natural attractions. This quaint cabin offers plenty of space to relax and enjoy the peace and quiet. Cabin offers two bedrooms with 3 beds and 1 sleeper sofa in the living room. Enjoy two full bathrooms, a half bath and a full kitchen. Cabin is within walking distance of water access, boat ramp, fishing areas and a cute local seasonal restaurant.

Farm stay close to Iowa City, IA

15 min.-Iowa City, 5 min- Riverside Casino, & 35 min-Eastern Iowa Airport, Cedar Rapids, IA. Comfy beds, living room sectional pulls out to queen hide a bed, 32 acres, horseback riding (sm. fee)*, winter fun, & fishing pond. First 2 guests pay base price, then 3rd thru 10th guests pay an extra 30.00 EACH. NO PARTIES on our farm. We live on property in a separate home. Dogs welcomed (must be kenneled when you leave property). We have an oven and cookware in kitchenette. *contact for details.

Private Guest Lake House On 37 Acres In Country

Private guest lake house, located next to main house, on private lake in the country. 2 bedroom, 1 full bath, full kitchen, washer and dryer and large attached screen porch. Private 37 acres of woods and prairie. Fishing and walking trails. Great window views of lake, woods, prairies and river valley. Please note, this guest house is located 1 mile down a county maintained gravel road. 25 minutes from Galesburg, IL, 20 minutes from Monmouth, IL and 35 minutes from Macomb, IL.

Private & Modern. Near river and wildlife refuge!

Experience the outdoors in comfort from this modern cabin, situated next to the 2200 acre Princeton Wildlife Management Area, and the nearby Mississippi River. It is ranked as the most “Wish Listed” Iowa listing of 2025 on Airbnb. Are you into hiking, biking, fishing, hunting, boating, or other water, winter, and summer sports? This cabin can support it all! Sit back and relax on the large deck while enjoying a coffee & the local wildlife, flora, & fauna of the Mississippi Valley Region.

Private Lakefront Romantic Cottage w/Swimspa&sauna

This cozy cottage is for couples looking to escape from it all and regenerate on many levels. You'll have your very own steam shower ....check out the company description.... . "Featuring 10 acupuncture jets, sunken tub and a high efficiency steam engine, the 608P steam bath is designed to greatly increase your spa experience. Indulge yourself in a state of complete relaxation". You'll also enjoy the comfy bed, fully stocked kitchen, private deck and access to an amazing swimspa and sauna.

Buckman's Guesthouse BnB (5 Bedrooms+)

Enjoy the comfort and welcoming atmosphere of a home built to entertain family & friends. There are 5 guest bedrooms rooms: Room 1-King bed, sofa bed & recliner Room 2-Queen & sofa bed Room 3-Twin beds & convertible sofa Room 4-Queen & sofa bed Room 5-King & recliner Rooms 1,2 &5 have in suite bathrooms. Bathroom for room 4 is next door. Rooms 2 &3 share an inner door; ideal for parents with children. Breakfast is included. To book a room instead of the house, see separate listings.

Iowa Cabin:Rustic+Cozy. Lake Odessa Iowa Waterview

Lake Odessa is a hidden Iowa gem, perfect for those looking to escape into nature. It’s a great spot for outdoor enthusiasts who love duck hunting, fishing, kayaking, birdwatching & hiking. The lake hosts a variety of wildlife, bald eagles, herons, and migrating waterfowl. From the deck enjoy sunrise views over the water, quiet evenings by the fire, and the soothing sounds of nature all around. Our recently updated cabin is the perfect getaway from the bustle of everyday life.

The Fleetwood Bungalow with Dreamy Porch

Welcome to The Fleetwood Inn! A charming, cozy one-bedroom bungalow in the heart of Burlington, Iowa. Right between our bustling business district and our nostalgic downtown, this little house has vast character. My favorite feature is all the original built-ins and beams. You will love the Western American inspiration and vintage finds, modern touches throughout, and dreamy details in every corner. Just added a Saatva Organic mattress for extra comfort.

Rock River Escape

Enjoy your coffee, a nice bbq dinner, glass of wine, a good book, or just enjoy the sweeping views out of this cute bungalow. With 180 ft of unobstructed river views and river access, bring your fishing poles and get ready to relax and enjoy watching the water slowly drift by at this centrally located bungalow in a quiet residential neighborhood. Firepit with firewood provided. No parties allowed so please do not inquire about them.

The Vernon Street Guest House - Suite 2

Built in 1900 and renovated in 2022, Suite 2 shows little signs of the once quirky old space. Completely private, with all the amenities, it boasts a spacious bedroom, 1 bathroom, a fully equipped kitchen, dining area, living room with a desk for workspace, and a laundry room. While you're here, we hope you are able to relax and enjoy the well lit deck along with a cup of freshly roasted coffee, which we are happy to have provided.

Historic schoolhouse apartment

This stylish place to stay is perfect for short stays or longer term work needs. Quiet in a small town. Spacious, attention to style and detail. This 2nd floor apartment has an incredible view especially at sunset. Access to workouts in the gym, coin laundry, or outdoor seating in the shade. No smoking in the building. No pets. Friendly, local owners will make your stay as comfortable as possible.