Waterfront vacation rentals in Saint Charles County

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Top-rated waterfront rentals in Saint Charles County

Guests agree: these waterfront rentals are highly rated for location, cleanliness, and more.

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Guest favorite

Houseboat in Saint Charles

5 out of 5 average rating, 16 reviews

Water's Edge Leisure Houseboat

Spend some leisure time on a unique vintage 60s houseboat with a cozy 180 square feet of interior space providing basic essentials. Enjoy the view of the Mississippi River and the bluffs along the Great River Road. Your morning beverage will taste better with a beautiful sunrise or get lost in the sunset while relaxing next to the calm evening water. Whether you're looking for a peaceful getaway or a fun-filled adventure on the water, our property on the Mississippi River is the perfect choice.

Guest favorite

Home in Saint Charles

4.81 out of 5 average rating, 72 reviews

Peaceful & Cozy Stay

Escape to tranquility just 1.1 mi from New Town St. Charles. Our home harmonizes convenience with comfort—3 beds, 2.5 baths, a well-equipped kitchen, and breathtaking pond views. Connect to blazing-fast 1 GB internet. Start your day with coffee from nearby cafés, explore lakes for fishing, and relish Civic Green Park's tranquility. The amphitheater hosts family nights and concerts. Whether a special event or a relaxing day, our home is your gateway to comfort, convenience, and natural beauty.

Superhost

Home in Saint Charles

4.82 out of 5 average rating, 136 reviews

Main Street Hideaway

This house is located on historic Main Street in Saint Charles, Missouri. This means we are within walking distance of dozens of restaurants and boutique shops. We are in the wedding district and three wedding venues are within a 5 minute walk: The Conservatory, The Old Stone Chapel, and LaBelle Couer. This is the perfect spot for bridal parties and families. This unique house, is a perfect spot for a bridal party to get ready and prepare for the big day. Brand new bath added in 2024.

Home in Lake Saint Louis

4.69 out of 5 average rating, 51 reviews

Lake Saint Louis Family Friendly Lakefront Retreat

Stay comfortably in our 5 bedroom 4400 sq ft Ranch home, 3.5 acre lake front estate in Lake St Louis. A short 2 min walk or drive down the lake road brings you to the Beach front and dock where you can Swim, Kayak and Paddle Board from our private sand beach or just relax on our private dock and picnic area. You’ll love our secluded large private wooded estate, with endless wildlife, flora and fauna and several short nature trails. All seasons are enjoyed on our estate and full of nature.

Guest favorite

Cabin in Portage Des Sioux

4.95 out of 5 average rating, 41 reviews

Serene Cabin on the Mississippi River w/kayaking!

* SPRING TO FALL 2025! This is our serene cabin situated on the banks of the Mississippi River at Portage Paddle Camp! Stay at our unique riverfront property, where we also offer rare, vintage accomodations for primitive-style camping! The river and bluff views will hypnotize you into relaxation. Enjoy sounds of occasional crashing waves, the beauty of nature, & peace! The hanging bed will rock you right to sleep. Grab a paddle and go kayaking or paddleboarding! Relax, renew, restore!

Top guest favorite

Loft in Saint Charles

4.98 out of 5 average rating, 57 reviews

Lovely Couples Escape on Mississippi River!

Overlooking the Mississippi River, this welcoming 1-bath studio cabin brings days of bliss, rest, and rejuvenation. Feel right at home as you enjoy all that this charming vacation rental has to offer. Start your day enjoying breakfast on the deck. Then, step out and explore Castlewood State Park, visit the Historic District’s shops and eateries, and taste your way through some of Missouri’s top-notch wineries. Top off the day by returning to a cozy campfire or a movie night on the Smart TV!

Superhost

Home in Saint Charles

4.75 out of 5 average rating, 4 reviews

Cozy Home in St. Charles

Nestled in the heart of St. Charles, our cozy home offers a perfect blend of comfort, style, and convenience for your stay. Whether you're here for business, leisure, or a bit of both, our space is designed to make you feel right at home. Family-friendly with its walkability to restaurants, bars, market, coffee shops, ice cream, food kiosk, canals, lakes, parks. It is only a few miles from historic St. Charles Main street, The Streets of St. Charles, and 25 miles to Downtown St. Louis.

Superhost

Townhouse in St. Louis

4.82 out of 5 average rating, 11 reviews

The Journey Home | JZ Vacation Rentals

This spacious 4-bedroom, 3.5-bath home is perfect for creating unforgettable family memories. Comfortably accommodating up to 14 guests, it features a fully stocked kitchen with stainless steel appliances and a basement game room for added entertainment. Enjoy modern amenities, including WiFi, cable streaming, a washer/dryer, a highchair, and a pack-n-play. The master suite boasts an en-suite bath, while the additional bedrooms offer cozy and inviting spaces for a restful stay.

Top guest favorite

Loft in St. Louis

5 out of 5 average rating, 21 reviews

`The VLuxe Oasis with City Skyline Views

Imagine waking up in a luxurious 2-bedroom, 2-bathroom loft with your own private balcony overlooking the bustling city of Downtown St. Louis. As you step onto the balcony and take in the breathtaking views of the vibrant city of St. Louis you will feel a dopamine release. Just minutes away from the iconic Arch, Enterprise Center, Ballpark Village and much more you'll feel the excitement and energy of the city right at your fingertips.

Cabin in Saint Charles

4.83 out of 5 average rating, 53 reviews

Chase's Cabin in The Sky

Take it easy at this unique and tranquil getaway. Close to St Charles but far enough for privacy. Large Deck for River Viewing of Wildlife and Bird Watching. St Charles County Park close by with walking trails, boat dock, fishing, playground, and Canoe and Kayak rentals. Lots of Great Restaurants and Activities close by. Six Flags, St Louis Cardinals, St Louis Blues, St Louis City SC Soccer, City Museum, Arch, Lots of Museums.

Top guest favorite

Home in Augusta

5 out of 5 average rating, 34 reviews

Welcome to the Owls Nest!

Welcome to the quiet magical town of Augusta, enjoy the comforts of home with 2 bedrooms, ample living space, fully stocked kitchen, screened in patio to enjoy a cold drink or glass of wine while taking in a beautiful view. Walk to the local wineries or ride your bike on the Katy Trail, kids can enjoy the local town playground directly across the street. Local market, antique store and fine dining within steps.

Home in Florissant

4.73 out of 5 average rating, 157 reviews

Large Family Home -Fall & Winter Getaway

Secluded Oasis nestled in a quiet neighborhood. Large 2 Story Home with 4 card private driveway is surrounded by neighborhood restaurants and grocery stores ensuring you can spend most of your time relaxing. Secluded First floor Master designed for main guest adjacent to Tiki Room and 3 private bedrooms upstairs Minutes away from major highways to Downtown & Saint Charles book now!