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Bed and breakfast vacation rentals in Saint Charles County

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Top-rated bed and breakfast rentals in Saint Charles County

Guests agree: these bed and breakfast rentals are highly rated for location, cleanliness, and more.

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A bright living area features light-colored walls and a cozy ambiance. A spacious dark sofa is complemented by a patterned area rug and a wooden coffee table. A large TV is placed on a storage unit, and a stylish light fixture hangs from the ceiling. Potted plants add a touch of greenery.

Home in St. Louis

4.87 out of 5 average rating, 571 reviews

Sunny 2 Bedroom Apartment in Historic Home

Recently renovated sunny 2 bed, 1 bath apartment on the top (3rd) floor of an historic home in the Central West End. Private entrance off driveway, with street parking available. A great place to stay while exploring the best St. Louis has to offer! Walk to shops, restaurants, universities, and medical centers. Close to public transportation, and an 8 minute drive from downtown. We welcome guests of all backgrounds. Whether you're traveling for work, fun, or family, we are happy to host you.

Private room in Saint Charles

5 out of 5 average rating, 13 reviews

Corner Cottage B&B and Antiques, LLC

Welcome to the Corner Cottage B&B. Enjoy a private queen bedroom with unattached bath including many amenities & breakfast. A living room, patio, porch, WiFi & satellite TV are also available. You'll be within walking distance of many gift shops, antiques stores, restaurants, the Missouri River & the Katy Trail on historic Main Street in St. Charles, MO. This Historic District is known for frequent historical events & festivals. The Family Arena & casinos are nearby; St Louis is minutes away.

A charming bedroom features a spacious bed layered with colorful pillows and a textured throw. Brightly painted walls are adorned with an array of artwork and photographs. Natural light filters in through large windows, while a ceiling fan adds a touch of elegance to the vibrant decor.

Home in St. Louis

4.99 out of 5 average rating, 108 reviews

Kalisto House: 420 Retreat w/Concierge & Hottub

Take it easy at this tranquil BNB retreat in historic Tower Grove Heights, St. Louis. Nestled in a preserved 120-year-old flat, Kalisto House offers an immersive experience for the canna-curious to the Cannaseur. With cannabis-inspired art, a serene meditation room, and concierge service, this sanctuary invites you to explore, unwind, and connect. From personalized pairings to guided rituals, every detail is curated for an unforgettable, elevated escape. Ask about premium & bespoke experiences.

A spacious mansion is set against a backdrop of tree-lined woods under a softly colored sky at dusk. The structure features a combination of dark and light siding with multiple windows and a symmetrical design. A gravel driveway leads to the entrance of the home.

Farm stay in Wentzville

Chickadee Farm Bed & Breakfast-4 Beds/8 Guests

We offer a gorgeously decorated mansion in the middle of a private, rural setting. There are many opportunities for a one-of-a-kind experience with wooded trails, Peace Garden, .4-acre stocked fishing lake, campfire rings, puzzles and games, ping pong, and more. We take breakfast seriously with what might be the world's best coffee, an enormous selection of teas, various Keurig cups, and a hearty, delicious meal that may include Billion Dollar Bacon to start your day & get you on your way.

Top guest favorite

Private room in St. Louis

5 out of 5 average rating, 72 reviews

Berra's Beginnings.

Child home of the late Hall of Famer Yogi Berra. Located in the heart of the beautiful, historic Hill neighborhood. The Hill neighborhood is filled with lots of attractions and restaurants within walking distance from our listing. The neighborhood boosts historic Italian heritage. As an added plus the host will be offering a full/hot breakfast along with golf cart transportation to sights, restaurants, bars (etc) within The Hill neighborhood (at NO additional cost!) *Price is Per Bedroom*

Private room in Wentzville

"The Barn" Room at Chickadee Farm B&B

We offer a gorgeously decorated mansion in the middle of a private, rural setting. There are many opportunities for a one-of-a-kind experience with wooded trails, Peace Garden, .4-acre stocked fishing lake, campfire rings, puzzles and games, ping pong, and more. We take breakfast seriously with what might be the world's best coffee, an enormous selection of teas, various Keurig cups, and a hearty, delicious meal that may include Billion Dollar Bacon to start your day & get you on your way.

Top guest favorite

A modern bedroom is shown, featuring a twin bed with gray bedding and a cushioned headboard. A wooden desk with a chair is positioned nearby, along with a mini fridge and dresser. Natural light filters through the window, partially covered by blinds.

Private room in University City

4.79 out of 5 average rating, 111 reviews

Modern Bnb Style Room & Home in Easy Access Suburb

Modern urban/suburban studio/bed and breakfast fusion style accommodations. Suburban exterior and neighborhood with urban interior. Studio sized proximity to all the amenities for ample apartment living with a traditional bed and breakfast layout of homey common spaces, opportunities to meet other travelers if desired, and as much or as little personalized on-site hosting as needed. Convenient central location in the heart of the city within an 18 minute drive to any of the metro area.

Private room in St. Louis

4.94 out of 5 average rating, 252 reviews

MoBot Passes & Great Breakfast Y

NO ADDITIONAL FEES. A true BNB in an architecturally classic home built in 1896 steps from the Missouri Botanical Garden Glow. My guests amenities include: 4 Free passes to the Missouri Botanical Garden ($15/person saving, additional discounted fee charged for Garden Glow) A full hot gourmet breakfast Queen Bed Sitting Area with Pull Out Full Sleeper Flip Sofa Private Bath USB outlets Bose speakers WiFi Micro fridge No cleaning fee No guest chores (bed stripping, cleaning, etc)

Top guest favorite

A cozy bedroom features soft pink walls, complemented by simple wall shelves displaying small decorative items and photographs. A spacious bed is dressed in a chocolate-colored quilt, flanked by matching nightstands with warm bedside lamps. Natural light filters through the room, enhancing the serene ambiance.

Private room in St. Louis

4.95 out of 5 average rating, 318 reviews

MoBot Passes & Great Breakfast P

NO ADDITIONAL FEES. A true BNB in an architecturally classic home built in 1896, steps from the Missouri Botanical Garden Glow. My guests amenities include: A full hot gourmet breakfast 4 Free passes to the Missouri Botanical Garden ($15/person saving, additional discounted fee charged for Garden Glow) Queen Bed Sitting Area with Pull Out Full Sleeper Flip Sofa Micro fridge Shared Bath with Host USB outlets WiFi No cleaning fee No guest chores (bed stripping, cleaning, etc)

A wooden staircase with ornate banisters leads to the upper level of the home. Natural light filters through a window at the landing, highlighting the rich hardwood floors. A decorative wall piece is mounted nearby, and a small metal rack is positioned at the bottom of the stairs.

Home in St. Louis

4.92 out of 5 average rating, 994 reviews

Benton Manor, 5 mins from everything in the city

This attractive two bedroom home with finished basement that has additional beds is conveniently located in the historic Benton Park area just slightly west of the Soulard neighborhood. Historic charm with all the modern amenities. Beautiful hardwood floors, high ceilings with grand windows and staircase await. Why stay in a hotel when you can have so much more for less?

A spacious room features a King-sized bed adorned with a patterned throw, accompanied by a pullout sleeper sofa. Two pieces of wall art add a touch of color, while a large television and a dark wood cabinet provide functionality. Soft lighting enhances the inviting ambience.

Hotel room in St. Louis

4.9 out of 5 average rating, 906 reviews

King Redwood Bedroom at BnB in CWE!

This is the largest of the rooms we have at our CWE BnB - an historic house in St. Louis' premier neighborhood. It has one King sized bed, a pullout sleeper sofa, two back-to-back 45" 4K Smart TVs with Rokus, and bathroom and kitchen space shared with guests of other rooms on this floor. Within a short walk of the basilica and many bars and restaurants in the CWE!

A welcoming guest room features a queen-sized bed with a brass frame and patterned bedding. A wooden side table is positioned beside the bed. A small work desk and chair are situated near the window, while soft lighting casts a warm glow in the space.

Hotel room in St. Louis

4.87 out of 5 average rating, 638 reviews

Evergreen Room Queen Bed at BnB in CWE

This is one of the available rooms we have at our BnB in the Central West End - a 125 year old house in one of St. Louis' most historic neighborhoods. It has one Queen sized bed, a kitchen space and bathroom shared with two other guest rooms on the floor. Within a short walk of the basilica and many bars and restaurants!

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Popular amenities for Saint Charles County bed and breakfast rentals

Free parking on premises

Air conditioning

Family-friendly bed and breakfast rentals

Top guest favorite

A modern bedroom is shown, featuring a twin bed with gray bedding and a cushioned headboard. A wooden desk with a chair is positioned nearby, along with a mini fridge and dresser. Natural light filters through the window, partially covered by blinds.

Private room in University City

4.79 out of 5 average rating, 111 reviews

Modern Bnb Style Room & Home in Easy Access Suburb

Top guest favorite

A cozy bedroom features a vintage white bed adorned with decorative pillows and a patterned quilt. A wooden chest sits at the foot of the bed, complemented by a small decorative tree nearby. Natural light filters through sheer curtains, illuminating the warm wooden floor.

Private room in St. Louis

4.96 out of 5 average rating, 25 reviews

Casa Magnolia Bed & Breakfast

A classic three-story brick home features a distinct arched doorway and large, rounded windows. The structure is complemented by greenery in the front yard, with steps leading to the entrance. The roof has a small turret-like feature, adding to its architectural charm.

Private room in St. Louis

4.94 out of 5 average rating, 252 reviews

MoBot Passes & Great Breakfast Y

Top guest favorite

Private room in St. Louis

5 out of 5 average rating, 72 reviews

Berra's Beginnings.

A spacious room features a King-sized bed adorned with a patterned throw, accompanied by a pullout sleeper sofa. Two pieces of wall art add a touch of color, while a large television and a dark wood cabinet provide functionality. Soft lighting enhances the inviting ambience.

Hotel room in St. Louis

4.9 out of 5 average rating, 906 reviews

King Redwood Bedroom at BnB in CWE!

Top guest favorite

A cozy bedroom features soft pink walls, complemented by simple wall shelves displaying small decorative items and photographs. A spacious bed is dressed in a chocolate-colored quilt, flanked by matching nightstands with warm bedside lamps. Natural light filters through the room, enhancing the serene ambiance.

Private room in St. Louis

4.95 out of 5 average rating, 318 reviews

MoBot Passes & Great Breakfast P

A welcoming guest room features a queen-sized bed with a brass frame and patterned bedding. A wooden side table is positioned beside the bed. A small work desk and chair are situated near the window, while soft lighting casts a warm glow in the space.

Hotel room in St. Louis

4.87 out of 5 average rating, 638 reviews

Evergreen Room Queen Bed at BnB in CWE

Bed and breakfast rentals with breakfast

Top guest favorite

A modern bedroom is shown, featuring a twin bed with gray bedding and a cushioned headboard. A wooden desk with a chair is positioned nearby, along with a mini fridge and dresser. Natural light filters through the window, partially covered by blinds.

Private room in University City

4.79 out of 5 average rating, 111 reviews

Modern Bnb Style Room & Home in Easy Access Suburb

Private room in St. Louis

4.94 out of 5 average rating, 252 reviews

MoBot Passes & Great Breakfast Y

Top guest favorite

Private room in St. Louis

5 out of 5 average rating, 72 reviews

Berra's Beginnings.

A spacious room features a King-sized bed adorned with a patterned throw, accompanied by a pullout sleeper sofa. Two pieces of wall art add a touch of color, while a large television and a dark wood cabinet provide functionality. Soft lighting enhances the inviting ambience.

Hotel room in St. Louis

4.9 out of 5 average rating, 906 reviews

King Redwood Bedroom at BnB in CWE!

A modern lounge area features a vibrant red couch with decorative pillows, positioned against a textured brick wall. A large art piece adorns the wall above, complemented by floating shelves holding books and decorative items. A wooden ladder leans against the wall, adding to the eclectic design.

Townhouse in St. Louis

4.88 out of 5 average rating, 501 reviews

Dwell 912 B&B- Modern Guest House Downtown-Soulard

Top guest favorite

A cozy bedroom features soft pink walls, complemented by simple wall shelves displaying small decorative items and photographs. A spacious bed is dressed in a chocolate-colored quilt, flanked by matching nightstands with warm bedside lamps. Natural light filters through the room, enhancing the serene ambiance.

Private room in St. Louis

4.95 out of 5 average rating, 318 reviews

MoBot Passes & Great Breakfast P

A wooden staircase with ornate banisters leads to the upper level of the home. Natural light filters through a window at the landing, highlighting the rich hardwood floors. A decorative wall piece is mounted nearby, and a small metal rack is positioned at the bottom of the stairs.

Home in St. Louis

4.92 out of 5 average rating, 994 reviews

Benton Manor, 5 mins from everything in the city

A welcoming guest room features a queen-sized bed with a brass frame and patterned bedding. A wooden side table is positioned beside the bed. A small work desk and chair are situated near the window, while soft lighting casts a warm glow in the space.

Hotel room in St. Louis

4.87 out of 5 average rating, 638 reviews

Evergreen Room Queen Bed at BnB in CWE

Other bed and breakfast vacation rentals

Top guest favorite

A modern bedroom is shown, featuring a twin bed with gray bedding and a cushioned headboard. A wooden desk with a chair is positioned nearby, along with a mini fridge and dresser. Natural light filters through the window, partially covered by blinds.

Private room in University City

4.79 out of 5 average rating, 111 reviews

Modern Bnb Style Room & Home in Easy Access Suburb

Private room in St. Louis

4.94 out of 5 average rating, 252 reviews

MoBot Passes & Great Breakfast Y

Top guest favorite

Private room in St. Louis

5 out of 5 average rating, 72 reviews

Berra's Beginnings.

A spacious room features a King-sized bed adorned with a patterned throw, accompanied by a pullout sleeper sofa. Two pieces of wall art add a touch of color, while a large television and a dark wood cabinet provide functionality. Soft lighting enhances the inviting ambience.

Hotel room in St. Louis

4.9 out of 5 average rating, 906 reviews

King Redwood Bedroom at BnB in CWE!

A modern lounge area features a vibrant red couch with decorative pillows, positioned against a textured brick wall. A large art piece adorns the wall above, complemented by floating shelves holding books and decorative items. A wooden ladder leans against the wall, adding to the eclectic design.

Townhouse in St. Louis

4.88 out of 5 average rating, 501 reviews

Dwell 912 B&B- Modern Guest House Downtown-Soulard

Top guest favorite

A cozy bedroom features soft pink walls, complemented by simple wall shelves displaying small decorative items and photographs. A spacious bed is dressed in a chocolate-colored quilt, flanked by matching nightstands with warm bedside lamps. Natural light filters through the room, enhancing the serene ambiance.

Private room in St. Louis

4.95 out of 5 average rating, 318 reviews

MoBot Passes & Great Breakfast P

A wooden staircase with ornate banisters leads to the upper level of the home. Natural light filters through a window at the landing, highlighting the rich hardwood floors. A decorative wall piece is mounted nearby, and a small metal rack is positioned at the bottom of the stairs.

Home in St. Louis

4.92 out of 5 average rating, 994 reviews

Benton Manor, 5 mins from everything in the city

A welcoming guest room features a queen-sized bed with a brass frame and patterned bedding. A wooden side table is positioned beside the bed. A small work desk and chair are situated near the window, while soft lighting casts a warm glow in the space.

Hotel room in St. Louis

4.87 out of 5 average rating, 638 reviews

Evergreen Room Queen Bed at BnB in CWE

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