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Vacation rentals in South Tucson

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in South Tucson

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Guesthouse in Tucson
4.96 out of 5 average rating, 521 reviews

The Zendo Oasis. Your Private Resort in Tucson.

Discover the Zendo Oasis, your private resort in midtown Tucson. Don't settle for a sterile hotel room that can cost hundreds more. The Zendo offers a retreat atmosphere that will impress. Exercise in our full gym and luxuriate in a hot stone sauna! After, jump in the pool! Sip wine while enjoying evenings around a chiminea under starlit skies. Lounge by the pool in the sun or shade on the deck or under louvered patios. The Zendo is close to the UA and downtown. Book now and escape the ordinary!

Top guest favorite
Home in Barrio Viejo
4.95 out of 5 average rating, 226 reviews

Cimarrones Barrio Viejo

Cimarrones is an historic property located in the heart of Tucson's charming Barrio Viejo. Completely renovated in 2021, the building is now a duplex, with Cimarrones fronting the picturesque street. While the charm of the historic elements - the thick adobe walls, high ceilings with wood vigas, brick paver floors - has been preserved, a selective choice of luxury contemporary conveniences, fixtures and finishes will make your stay supremely comfortable. Arizona TPT License # 21469803

Superhost
An outdoor seating area is framed by wooden pillars, featuring a black table and chairs beneath a vibrant blue umbrella. A decorative area rug lies on the ground, surrounded by potted plants, while distant shrubs provide a natural backdrop.
Bungalow in Tucson
4.88 out of 5 average rating, 754 reviews

Perfect casita Minutes from U of A & downtown!

Brand new home located near the downtown area . Minutes from all Gem shows and Kino soccer fields. Many restaurants and bars nearby. There is also a Costco, Walmart, and movie theater nearby. 24 hour post office around the corner . This home is a few minutes to the U of A. 15 minutes from the airport. Very convenient location. Parking on premises. Open 600 sq ft space with two queen beds. Kitchen, bathroom & shower. The yard is gated so you can have pets outside only, NOT inside

Top guest favorite
An inviting entrance showcases a wooden door with multiple panels, leading to a simple, open corridor. A framed artwork of a rider adorns the wall, while a cow skull adds a rustic touch above the doorway. Minimalist furnishings include a wooden bench and decorative cushions.
Home in Barrio Viejo
4.99 out of 5 average rating, 426 reviews

Barrio Viejo 1870 Adobe, KingBed, FirePit, downtwn

This unique, spacious, updated & authentic adobe is located in the historic Barrio Viejo of Tucson, nestled between downtown and Five Points. This desert Adobe has been abandoned since the 1970’s, but is now revitalized with new amenities, exposing the beautiful adobe walls and preserving the original ceilings. The fully stocked kitchen includes a gas range, dishwasher and granite countertops. Enjoy the smart TV in both the bedroom and living room. King size bed in bedroom

Top guest favorite
Bungalow in Tucson
5.0 out of 5 average rating, 31 reviews

The Downtown Gems! Clean, comfortable, and cozy! B

Relax in this clean cozy and comfortable Downtown Gem! The home (duplex) is located near the heart of Downtown Tucson Arizona, close to U of A and historic 4th Ave for food, fun, and laughter. One bedroom, with a comfortable queen size bed and a fold out bed in the living room. The views of the sunsets are breathtaking and the front patio has beautiful views! The unit has a full kitchen, dining area, living room, bathroom (grab bars in shower), bedroom, and a closet.

Top guest favorite
Home in Tucson
4.96 out of 5 average rating, 250 reviews

Modern Farmhouse in Midtown

Comfortable and cozy modern farmhouse in midtown Tucson is near Reid Park, with quirky southwestern farmhouse style just minutes from U of A and Saguaro National Park. Enjoy the great weather with an outdoor charcoal grill and dining space plus a view of the mountains or get cozy around the fire pit and enjoy the native desert plants. We have high-speed Wi-Fi and two TVs with DISH or enjoy family time with one of our many board games. Your dogs will love the fenced yard!

Guest favorite
Home in Tucson
4.85 out of 5 average rating, 13 reviews

Casa Hermanita~Sunny Simple & Cozy

Casa Hermanita, a newly built casita 750 sq ft in south-central Tucson offering a calm desert inspired vibe. Enjoy an open floor plan, spacious bedrooms, and thoughtfully touches throughout. A relaxing place to unwind after exploring the city. Located in a friendly authentic Tucson neighborhood. We’re 10 minutes from Tucson Convention Center & Downtown, minutes from the Tucson Gem Show venues, a block away the Huckleberry Bike Path and with quick access to I-10 & I-19.

Top guest favorite
A charming front porch is visible, featuring natural stone steps leading to a wooden front door. Colorful plants are placed in pots, and hanging red chili peppers are displayed from the ceiling. Sunlight filters through the trees, creating a warm ambiance.
Home in Tucson
5.0 out of 5 average rating, 41 reviews

3 Bed. Walk to Tucson Gem Show

Welcome to Casa Azul! Tucked in the heart of the historic Barrio Santa Rosa neighborhood, our home is just blocks from the world-famous Tucson Gem Show, the vibrant 5 Points district, Bar Crisol/Exo, and downtown’s best spots. Known by locals as a central hub for culture, food, and community, this area offers an authentic Tucson vibe. With 3 bedrooms, 3 full baths, a pool, work-from-home spaces, and a grill on the covered patio, Casa Azul is your perfect home base.

Top guest favorite
The living area features a large sectional sofa facing a 65" smart TV, complemented by a dining table surrounded by black chairs. Natural light is welcomed through the open layout, and stairs are visible in the background leading to the upper level.
Apartment in Tucson
5.0 out of 5 average rating, 104 reviews

Modern Stylish Downtown Loft, By UofA + Foodie Hub

Secure Downtown Loft: Walk Everywhere! Modern loft in gated Flash TV courtyard between UofA (7min), Downtown (1min) & 5Points. Full kitchen, standing desk, fast WiFi, powerful AC mini-splits keep you cool. In-unit w/d, smart TVs, dedicated parking. Self check-in anytime. Walk to Convention Center, streetcar, dozens of restaurants/bars on 4th Ave & 5Points foodie scene. Perfect for remote work, campus visits, or exploring Tucson's UNESCO City of Gastronomy.

Top guest favorite
An inviting outdoor space features a cowboy swimming pool surrounded by a patio area with comfortable seating. A wooden table and stylish chairs complement the relaxing atmosphere. The walls showcase vibrant murals and string lights enhance the ambiance for evening enjoyment.
Home in Barrio Viejo
4.87 out of 5 average rating, 141 reviews

CASA ALMA /Cowboy Pool /Game Rm

Your Casa in Barrio Vijeo is centrally located 5-10 minutes from the University of Arizona, vibrant downtown Tucson, and walking distance to the Tucson Convention Center. The Mountain Avenue bikeway is a hop and skip away while some of the city’s most scenic hiking and biking trails are reachable in 20 minutes. Top nearby attractions include the El Presidio Historic District, Arizona-Sonora Desert Museum and awe-inspiring Saguaro National Park.

Guest favorite
Home in South Tucson
4.9 out of 5 average rating, 20 reviews

Relaxing home

Welcome to your home away from home! This bright and comfortable 4-bedroom (3Queen, 1full) , 2-bathroom house is the perfect getaway for families, groups, or anyone looking for plenty of space close to the action. Fully equipped. Located just minutes from downtown, you’ll have quick access to shops, restaurants, parks, and local attractions—while still enjoying the peace and comfort of a quiet residential neighborhood.

Guest favorite
Apartment in Tucson
4.87 out of 5 average rating, 238 reviews

Sweet 1 Bedroom Near Downtown with a CAT

Relax in this 500sf 1-bedroom urban retreat with a lot of unique charm and A CAT 🐈‍⬛** One mile from the heart of downtown, a comfortable queen bed, a comfortable couch-bed, dining table, fast WIFI, shower with endless hot water, full kitchen, 24-hour access to a private hot tub, our relaxing shared back yard with trees, a fire pit, a chiminea, many feral cats, and turtles. ** read about cat below

Popular amenities for South Tucson vacation rentals