
Guesthouse vacation rentals in Santo Domingo
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in Santo Domingo
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

Centric & Elegant Studio/Colonial Style/Ample Yard
Unique studio within a renovated property. Large patio with fence and electric gate. Ideally located, 2 miles away from the Colonial Zone, 3 from Downtown. Hospital, Laundry, Sea View within 2 blocks. Supermarket, restaurants, museums within 1 mile. Less than 0.5 miles away from 2 subway stations. Fast Wifi (100+ Mbps). Smart speaker can control lights, AC, adjust temperature or play your favorite music. 4K TV w/swivel base, includes YouTube, Netflix, PrimeVideo, Disney and Star+. Queen bed.

Private Cozy Apartment Studio
One bedroom studio, centrally located in the heart of El Millón, Santo Domingo, where comfort, convenience, and warm space offers the intimate feel of a family home, featuring: A private entrance for your complete privacy. Dedicated parking for your convenience and peace of mind. Whether you're visiting for leisure or business, our studio is thoughtfully designed to meet your needs. Remote workers will appreciate the high-speed internet, ensuring uninterrupted connectivity throughout your stay.

Cozy 2 BR with BBQ
This 2 bedroom apartment with BBQ private area is truly bright and cozy . It takes 25 minutes to arrive from the airport. The spacious master bedroom has a queen size bed and the very bright single room have two twins bed. You have discount with our car rental services with airport pick-up. The neighborhood is very safe, is private with access control and very clean, there are many restaurants nearby many bars, gyms, movie theaters, shopping malls . The neighbours are lovely and quiet.

Santo Domingo studio apartment 40 minutes from the beach.
will have the entire studio apartment just for you, enjoy the tranquility provided by the sector, an ideal place for rest and work, and a strategic point to move to places of interest cleaning of the accommodation is at your expense during the stay, it is given to you clean, if you need you can request cleaning service with additional charge. the patio is shared very few times, usually only you will enjoy the patio, the host is in charge of cleaning the patio area.

Private Oasis with Pool, Garden and Terrace.
Enjoy a private oasis designed for rest. An exclusive space with a swimming pool, large garden, and terrace perfect for relaxing or sharing with the family. Ideal for those seeking tranquility, privacy and comfort without leaving the city. The property offers: - Exclusively used pool - Garden surrounded by nature -Terrace Safe and private environment Close to supermarkets, restaurants and main roads A place to disconnect, enjoy peace and create special moments.

Dorita's little house
Enjoy a quiet, comfortable and private space, where you can rest, work and get to know Santo Domingo. This home is located 35 mins from Boca Chica beach and 15 mins from the National District. It's also less than 5 minutes away. Supermarkets, squares, clinics, fast food restaurants, recreation park, fuel station, shipping agencies and pharmacies. WE DO NOT RECEIVE DIFFERENT PEOPLE AT THE ACCOUNT OWNER

Cozy apartment for work / holidays.
Comfortable apartment, on second level, with private parking, ideal for holiday trips, congresses, jobs and others. Close to shopping centers, Recreational park, clinics, universities; 25 minutes from the colonial area. Located in downtown area of the city, in the urbanization El Millón del Distrito Nacional. Peaceful, residential place with access to the main roads of the city.

Guest House w/Pool near the American Embassy
You no longer need to leave the city to feel in the mountains, this is an independent 1 bed 1 bath Guest House in a closed residence with a 10-meter pool shared with the Hosts. With a Coway potable water filter. Supermarkets, Cinema, Shops, and Hair Salon nearby. A few minutes from the center of Santo Domingo and 1.8 km from the American Embassy.

Your little corner of peace in SDO
Kick back and relax in this calm, stylish space. “Tu rinconcito de Paz” is an oasis in the middle of the city rush, take some fresh air in our outdoor Gazebo area, enjoy the privacy and security of our small but cozy house. Commercial centers as Carrefour and numerous restaurants are located at 8 minutes away from our spot.

US Embassy Suites
Have fun with the whole family at this stylish place while taking it easy at a unique and tranquil getaway. Perfect while on the go or for appointments at the U.S. embassy. Guesthouse comes included with access to an olympic style pool, outdoor patio and barbecue grill. Great for evening get togethers and celebrations.

Mamuchi House apartment, Zona Franca San Isidro
2 bedroom apartment with A/C, private bathroom, 3rd. Apartment. Ideal for you who are looking for a comfortable space near the Zona Franca de San Isidro and Air Base, you rest in a family atmosphere. Base rate valid for 2 people, one room.

Your cozy little guest house
Enjoy your stay! Comfortable and pleasant guest house on the ground floor (no stairs, no elevators) cool patio, in the city center, near the Quisquella Stadium, Plaza de la Salud, shopping malls, etc.
Popular amenities for Santo Domingo guesthouse rentals
Family-friendly guest house rentals

Villa El Cocotero

Our Home Zudelyn H6

U.S. Embassy Stay Inn

Luxury house in Las Américas, 10 minutes from the airport

Casa Doña Beba

Our Home Zudelyn H8

Centrally located and unique colonial-style studio

Furnished with everything couples need
Guest house rentals with a patio

Nochebuena Room at Akaiah Guest House.

The best option

Beautiful room in the Colonial area

Relax in this cozy villa

Double suite room in Aut Las Américas

An excellent and private villa to be happy...

Charming Private Room & Bath in Heritage Hostel

Cozy second floor house with a pool and air conditioning
Guest house rentals with a washer and dryer

INVERTERS

Brisa Oriental

Comfortable and Cozy Apartamento

Bedroom inside apartment

Villa el paraíso, Guerra

Luxury apartment in Santuario

Casa en Villa Marina, Los Ríos de Santo Domingo

Secure★DCGen★Full Kitchen★100+Mbs★Comfy Bed★W/D
When is the best time to visit Santo Domingo?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$7,531 GYD | G$7,321 GYD | G$7,321 GYD | G$6,066 GYD | G$5,857 GYD | G$5,648 GYD | G$5,439 GYD | G$6,066 GYD | G$7,321 GYD | G$5,857 GYD | G$6,485 GYD | G$7,321 GYD |
| Avg. temp | 26°C | 26°C | 26°C | 27°C | 27°C | 28°C | 28°C | 28°C | 28°C | 28°C | 27°C | 26°C |
Quick stats about guesthouse rentals in Santo Domingo

Total vacation rentals
Explore 80 vacation rentals in Santo Domingo

Nightly prices starting at
Santo Domingo vacation rentals start at G$2,092 GYD per night before taxes and fees

Verified guest reviews
Over 1,200 verified reviews to help you choose

Pet-friendly vacation rentals
Find 20 rentals that welcome pets

Rentals with dedicated workspaces
40 properties have a dedicated workspace

Wi-Fi availability
70 of Santo Domingo vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Santo Domingo rentals

4.5 Average rating
Santo Domingo stays receive an average rating of 4.5 out of 5 from guests
Destinations to explore
- Punta Cana Vacation rentals
- San Juan Vacation rentals
- Las Terrenas Vacation rentals
- Santiago De Los Caballeros Vacation rentals
- Santo Domingo Este Vacation rentals
- Puerto Plata Vacation rentals
- Sosúa Vacation rentals
- La Romana Vacation rentals
- Cabarete Vacation rentals
- Bayahibe Vacation rentals
- Juan Dolio Vacation rentals
- Carolina Vacation rentals
- Loft rentals Santo Domingo
- Serviced apartment rentals Santo Domingo
- Ski-in/ski-out rentals Santo Domingo
- Rentals with a sauna Santo Domingo
- Hotel rooms Santo Domingo
- Boutique hotels Santo Domingo
- Rentals with outdoor seating Santo Domingo
- Rentals with a fire pit Santo Domingo
- Aparthotel rentals Santo Domingo
- Condo rentals Santo Domingo
- Rentals with a fireplace Santo Domingo
- Rentals with pools Santo Domingo
- Beachfront rentals Santo Domingo
- Rentals with lake access Santo Domingo
- Rentals with an EV charger Santo Domingo
- Private suite rentals Santo Domingo
- Apartment rentals Santo Domingo
- Rentals with beach access Santo Domingo
- Bed and breakfasts Santo Domingo
- Pet-friendly rentals Santo Domingo
- Rentals with breakfast Santo Domingo
- Rentals with an accessible height bed Santo Domingo
- Rentals with a hot tub Santo Domingo
- Fitness-friendly rentals Santo Domingo
- Family-friendly rentals Santo Domingo
- Rentals with a washer and dryer Santo Domingo
- Rentals with a patio Santo Domingo
- Smoking-friendly rentals Santo Domingo
- Villa rentals Santo Domingo
- Rentals with a home theater Santo Domingo
- House rentals Santo Domingo
- Waterfront rentals Santo Domingo
- Mansion rentals Santo Domingo
- Vacation home rentals Santo Domingo
- Guesthouse rentals Distrito Nacional
- Guesthouse rentals Dominican Republic
- Playa Nueva Romana
- Playa Guayacanes
- Metro Country Club
- Ciudad Juan Bosch
- Playa Caribe
- Santo Domingo Country Club
- Teatro Nacional Eduardo Brito
- Playa La Sardina
- Parque Nacional Submarino La Caleta
- Playa Juan Dolio
- Playas de Meganito
- Bella Vista Mall
- Downtown Center
- Malecón
- Playa Hemingway
- Parque La Lira
- Playa Boca del Soco
- Things to do Santo Domingo
- Food and drink Santo Domingo
- Nature and outdoors Santo Domingo
- Things to do Distrito Nacional
- Food and drink Distrito Nacional
- Nature and outdoors Distrito Nacional
- Things to do Dominican Republic
- Tours Dominican Republic
- Sightseeing Dominican Republic
- Nature and outdoors Dominican Republic
- Entertainment Dominican Republic
- Sports activities Dominican Republic
- Art and culture Dominican Republic
- Food and drink Dominican Republic




