
House vacation rentals in Sant'Isidoro
Find and book unique houses on Airbnb
Quick stats about house rentals in Sant'Isidoro

Total vacation rentals
Explore 40 vacation rentals in Sant'Isidoro

Nightly prices starting at
Sant'Isidoro vacation rentals start at G$10,454 GYD per night before taxes and fees

Verified guest reviews
Over 110 verified reviews to help you choose

Family-friendly vacation rentals
20 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 20 rentals that welcome pets

Wi-Fi availability
10 of Sant'Isidoro vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Sant'Isidoro rentals

4.6 Average rating
Sant'Isidoro stays receive an average rating of 4.6 out of 5 from guests
Top-rated house rentals in Sant'Isidoro
Guests agree: these houses are highly rated for location, cleanliness, and more.

house in courtyard 2 Ca'mascìa
The house, renovated in keeping with its authenticity, is in the heart of the historic center of Matino, in one of the oldest courtyards, close to the Marchesale Palace. It is ideal for spending your holidays in absolute tranquility while being just a few km from Gallipoli and the most beautiful beaches of Salento. It is a penthouse with three terraces, one of which is panoramic from which you can admire the white houses of the town, the Salento countryside and the sea of Gallipoli with the lighthouse.
LocationAccuracyQuiet

La Casa di Celeste - Apartment with terrace
La Casa di Celeste is a delightful newly renovated apartment in the historic center of Lecce. Located in a pedestrian area, a stone's throw from restaurants and cocktail bars that animate the city, it is perfect for 2 people, small families or couples of friends. It consists of a double bedroom, a room with a sofa bed, a living room, a kitchen, a bathroom and a large terrace with a barbecue where you can dine with maximum privacy and from which you can enjoy a beautiful view of the square.
ValueLocationGrill

Petrammare of Casa Camilla Journey
Petrammare is an exclusive residence sheer over the sea in Tricase Porto, set on two levels. The ground floor offers a spacious living area with a large sofa, dining table, fully equipped kitchen with fridge, oven, microwave, dishwasher, and a third bathroom with a shower and washing machine. The first floor features two double bedrooms with AC, TV, and private en-suite bathrooms with a bidet. The property is completed by a huge outdoor space with a swimming pool and sea view furniture.
LocationNearbyView

Hélène Luxury Home Suite
Very central Luxury Home Suite! 100-square-meter Lecce stone residence in the historic center of LECCE. Suite HÉLÈNE is beautiful under starry vaults, minimal elements and modern touches. Lights and shadows in a dreamlike dimension! Services for a high-level stay: Relax in the small patio, comfort in its spaces and fabrics, regenerating bath in the majestic stone tub, heated floor, fully immersed in the sound diffused by a "full-sound" system: Style, Art, Love, Relaxation, Luxury...
LocationValueAir conditioning

Tricase Porto, beautiful with access to the sea
Vintage Salento-style apartment, recently renovated with great taste and all comforts. An outdoor space that can be used and a priceless private descent to the sea that makes bathing in coves and natural pools dug into the rocks exclusive and solitary, even on the busiest days of the summer! The apartment is part of a complex overlooking the sea that has a large condominium garden, a reserved space where you can eat under the stars and overlooking the sea and use the barbecue
ValueFamilyOutdoor spaces

Charming residence, panoramic rooftop, historic center
LA BORBONICA is a meticulously restored 19th-century residence transformed into an exclusive vacation home, where baroque dialogues with contemporary design. We are located in the heart of the historic center, among the most evocative streets of the city. This 110-square-meter apartment offers an immersive Salento experience, combining historical authenticity and modern comfort through handcrafted details and premium amenities. We are on the 1st floor, so it is very bright.
FamilyLocationParking

Small detached house
Take it easy in this unique and relaxing space. For short summer rentals, a small independent villa surrounded by greenery near the sea with a beautiful wooden ceiling 1.5 km from the sea! Private outdoor atrium Complete with all amenities: air conditioning, mosquito nets, coffee machine, washing machine, kitchen, clean dishes and towels, table and chairs outside, outdoor shower rack Suitable for spending your holidays in total peace of mind. Private outdoor parking
ValueLocationKitchen

On Caletta dell'Acquaviva, 20 meters from the sea.
The house "Perla dell 'Acquaviva" , in the middle of the Otranto-Leuca natural park , offers an enviable private access to the sea and the privilege of entering the waters of the cove through a comfortable rocky staircase different from the other bathers. The property consists of bathroom, bedroom, kitchen-living room, porch overlooking the sea. You will be welcomed by large outdoor spaces with a relaxation area among tall trees and the relaxing roar of the waves.
FamilyValueSleep quality

Exceptional house right on the beach.
° A two level house right on the beach. ° Terrace only a couple of meters from the sea. ° Modern design, new amenities, beautifully furbished. ° Ideally located to visit the jewels of the Salento, Italy's heel. ° Spectacular beach in seaside town. Desolate in winter. Great fun in high season. ° 55' from Brindisi Airport. ° Thomas and Els used to be the owners of another very appreciated holiday home. The older comments you'll read here are about that place.
LocationFamilyDecor

Relax between beaches and the city center
Relax in this peaceful independent star vaulted home, a typical architectural element of the place. Centrally located, a few meters from the waterfront and a 10-minute walk from the beach. Free private parking included in the price. The accommodation is brand new and equipped with a fully equipped kitchen, Wi-Fi, air conditioning, TV, hairdryer, and a private garden with a shower. It offers all the comforts to make your vacation in Salento special.
LocationFamilyOutdoor spaces

Nonna Maria
Alloggio tradizionale finemente ristrutturato, immerso nella tranquillità della campagna Salentina. Situato in posizione strategica tra Lecce, Gallipoli, Otranto e le splendide spiagge della costa ionica. Offre ambienti accoglienti con dettagli autentici e comfort moderni. All’esterno, un ampio giardino curato ideale per rilassarsi dopo una giornata al mare o in escursione. Perfetto per chi cerca charme, natura e comodità.
LocationValueOutdoor spaces

Poolside Paradise in Puglia - The Sweetness of Lecce
Welcome to your perfect retreat in Lecce, the baroque gem of Salento! This charming apartment, centrally located yet quiet, offers modern comfort, a cozy bedroom, a full kitchen, a small pool, and a rooftop terrace with outdoor shower, kitchen, and lounge. Steps from stunning architecture, shops, and restaurants, it’s ideal for relaxing after exploring town or the nearby beaches. Book now and enjoy the magic of Lecce!
LocationFamilyOutdoor spaces
Popular amenities for Sant'Isidoro house rentals
House rentals with a pool

Casa Santapietra
FamilyLocationSleep quality

Il Carrubo - Authenticity, Nature and Relaxation
LocationFamilyAccess

Casale Maddaloni
LocationFamilyView

Private pool in Lecce, steps from old town
LocationFamilyBathroom

Sea view apartment in Santa Caterina
FamilyLocationHospitality

villa le ozze
FamilyLocationAccuracy

Relais il Melograno- Relax in the heart of Salento
ValueLocationAmenities

Masseria Gemini, a XVIII century luxury retreat
LocationFamilyHospitality
Weekly house rentals

Oasi Sul Mare in Castro
LocationFamilyView

House ANEMONE on the beach
FamilyLocationCondition

Ancient Dimora Scalfo Galatina
LocationValueBreakfast

Fabulous historic Palazzetto breathtaking seaview
FamilyLocationQuiet

Villa with private access to the sea
FamilyLocationWalkability

An intimate nest for two
LocationAccessLaundry

Casina Mameli
LocationLayoutBeach

Vaults and Cementine in the Historic Center of Lecce
FamilyValueComfort
Private house rentals

24 May Apartment
ValueFamilyIndoor spaces

Le Scalere Salento
ValueFamilyAir conditioning

Holiday home 'Della mia felicità'
ValueFamilyIndoor spaces

Seaside villa in Porto Cesareo
ValueLocationPets

Dimora San Giovanni
ValueFamilyWalkability

Masseria: experience Salento, nature and tradition
ValueLocationCheckout

Beautiful villa with a sea view.
LocationViewCleanliness

Residenza SA - between the sea and the countryside
FamilyLocationPets
When is the best time to visit Sant'Isidoro?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$14,636 GYD | G$14,636 GYD | G$14,427 GYD | G$14,008 GYD | G$14,008 GYD | G$15,472 GYD | G$17,981 GYD | G$24,253 GYD | G$15,890 GYD | G$14,427 GYD | G$14,427 GYD | G$14,845 GYD |
| Avg. temp | 8°C | 9°C | 11°C | 14°C | 18°C | 23°C | 26°C | 26°C | 22°C | 18°C | 14°C | 10°C |
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- Rentals with beach access Sant'Isidoro
- Family-friendly rentals Sant'Isidoro
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- House rentals Apulia
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- Salento
- Spiaggia Di Pescoluse
- Trulli Valle d'Itria
- Punta della suina
- Baia Dei Turchi
- Torre Guaceto Beach
- Punta Prosciutto Beach
- Togo bay la Spiaggia
- Torre San Giovanni Beach
- Spiaggia Le Dune
- MAR.TA Museo Archeologico Nazionale di Taranto
- Spiaggia di Montedarena
- Lido Morelli - Ostuni
- Porto Selvaggio Beach
- Porta Napoli
- Spiaggia Sant'Isidoro
- Gate Of Saint Blaise
- Castello Aragonese
- Torre di Porto Miggiano
- Dune Di Campomarino
- Roman Amphitheatre
- Splash Parco Acquatico
- Giardini Pubblici Giuseppe Garibaldi
- Sant'Andrea and Litorale di Punta Pizzo Regional Nature Park





