
House vacation rentals in Sant'Isidoro
Find and book unique houses on Airbnb
Quick stats about house rentals in Sant'Isidoro

Total vacation rentals
Explore 40 vacation rentals in Sant'Isidoro

Nightly prices starting at
Sant'Isidoro vacation rentals start at G$10,460 GYD per night before taxes and fees

Verified guest reviews
Over 110 verified reviews to help you choose

Family-friendly vacation rentals
20 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 20 rentals that welcome pets

Wi-Fi availability
10 of Sant'Isidoro vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Sant'Isidoro rentals

4.6 Average rating
Sant'Isidoro stays receive an average rating of 4.6 out of 5 from guests
Top-rated house rentals in Sant'Isidoro
Guests agree: these houses are highly rated for location, cleanliness, and more.

Independent tower with panoramic terrace.
A few steps from the Duomo of Lecce and immersed in the Lecce Baroque, a 1600 tower is rented on 2 levels with an exclusive terrace to be able to eat outdoors overlooking the historic center. The property has a living area (with typical star and barrel vaults) with a sofa bed, smart TV, kitchenette with induction hob, fireplace and bathroom. On the first floor, there is a large double bedroom with a bathroom equipped with a shower and washing machine. Additional amenities: Wi-Fi and air conditioners.
ValueFamilyCondition

Private pool in Lecce, steps from old town
The pool is exclusively for you! Your small private oasis in the heart of Lecce. Relax in our lush garden, take a dip in your private pool, and enjoy a home-cooked meal with a glass of wine. Free parking is right in front the door. We provide everything for a perfect stay: toys, beach & pool essentials, umbrellas, sarongs, all cooking utensils, and speakers for your music on the terrace. A short walk takes you to Lecce’s historic center, and Salento’s stunning beaches are just 30 minutes away.
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La Casa di Celeste - Apartment with terrace
La Casa di Celeste is a delightful newly renovated apartment in the historic center of Lecce. Located in a pedestrian area, a stone's throw from restaurants and cocktail bars that animate the city, it is perfect for 2 people, small families or couples of friends. It consists of a double bedroom, a room with a sofa bed, a living room, a kitchen, a bathroom and a large terrace with a barbecue where you can dine with maximum privacy and from which you can enjoy a beautiful view of the square.
FamilyValueCleanliness

Petrammare of Casa Camilla Journey
Petrammare is an exclusive residence sheer over the sea in Tricase Porto, set on two levels. The ground floor offers a spacious living area with a large sofa, dining table, fully equipped kitchen with fridge, oven, microwave, dishwasher, and a third bathroom with a shower and washing machine. The first floor features two double bedrooms with AC, TV, and private en-suite bathrooms with a bidet. The property is completed by a huge outdoor space with a swimming pool and sea view furniture.
LocationFamilyOutdoor spaces

Hélène Luxury Home Suite
Very central Luxury Home Suite! 100-square-meter Lecce stone residence in the historic center of LECCE. Suite HÉLÈNE is beautiful under starry vaults, minimal elements and modern touches. Lights and shadows in a dreamlike dimension! Services for a high-level stay: Relax in the small patio, comfort in its spaces and fabrics, regenerating bath in the majestic stone tub, heated floor, fully immersed in the sound diffused by a "full-sound" system: Style, Art, Love, Relaxation, Luxury...
ValueLocationSleep quality

Oasi Gorgoni Charming House & Pool
Luxurious and comfortable apartment, close to the city center, ideal for enjoying relaxation, the city, and the sea. Equipped with every comfort (3 bedrooms, 3 bathrooms, living room, private pool, garden, Wi-Fi, air conditioning, washing machine, linens, dishes, private parking), the apartment is located in one of the quietest and safest neighborhoods in Lecce. Just 10 minutes from the sea, it offers easy access to both the Adriatic coast (Otranto) and the Ionian coast (Gallipoli).
FamilyLocationAccuracy

Historic residence in the center of Lecce, panoramic terrace
LA BORBONICA is a meticulously restored 19th-century residence transformed into an exclusive vacation home, where baroque dialogues with contemporary design. We are located in the heart of the historic center, among the most evocative streets of the city. This 110-square-meter apartment offers an immersive Salento experience, combining historical authenticity and modern comfort through handcrafted details and premium amenities. We are on the 1st floor, so it is very bright.
LocationFamilyView

On Caletta dell'Acquaviva, 20 meters from the sea.
The house "Perla dell 'Acquaviva" , in the middle of the Otranto-Leuca natural park , offers an enviable private access to the sea and the privilege of entering the waters of the cove through a comfortable rocky staircase different from the other bathers. The property consists of bathroom, bedroom, kitchen-living room, porch overlooking the sea. You will be welcomed by large outdoor spaces with a relaxation area among tall trees and the relaxing roar of the waves.
FamilyValueView

Exceptional house right on the beach.
° A two level house right on the beach. ° Terrace only a couple of meters from the sea. ° Modern design, new amenities, beautifully furbished. ° Ideally located to visit the jewels of the Salento, Italy's heel. ° Spectacular beach in seaside town. Desolate in winter. Great fun in high season. ° 55' from Brindisi Airport. ° Thomas and Els used to be the owners of another very appreciated holiday home. The older comments you'll read here are about that place.
LocationFamilyCheck-in

Casa Florean - Historic Center of Lecce
Casa Florean is a 19th century house located in the historic center, the typical vaults and the local stone walls of Lecce transform the permanence into an immersive experience in the past and in the tradition of Salento. The period furnishings have been carefully chosen to maintain the style of typical Lecce houses and modern comforts. Our dream is to offer guests an unforgettable stay in one of the most beautiful and monumental baroque cities in Italy.
FamilyValueSleep quality

Relax between beaches and the city center
Relax in this peaceful independent star vaulted home, a typical architectural element of the place. Centrally located, a few meters from the waterfront and a 10-minute walk from the beach. Free private parking included in the price. The accommodation is brand new and equipped with a fully equipped kitchen, Wi-Fi, air conditioning, TV, hairdryer, and a private garden with a shower. It offers all the comforts to make your vacation in Salento special.
FamilyLocationComfort

Nonna Maria
Finely renovated traditional accommodation, immersed in the tranquility of the Salento countryside. Strategically located between Lecce, Gallipoli, Otranto, and the beautiful beaches of the Ionian coast. It offers cozy spaces with authentic details and modern comforts. Outside, a large well-kept garden ideal for relaxing after a day at the beach or hiking. Perfect for those looking for charm, nature, and comfort.
ValueLocationIndoor spaces
Popular amenities for Sant'Isidoro house rentals
House rentals with a pool

Villa I 2 Leoni - Apartment 4 km from Lecce
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Ulivi al tramonto: country home with private pool
LocationFamilyWalkability

Relais il Melograno- Relax in the heart of Salento
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Poolside Paradise in Puglia - Il Dolce di Lecce
LocationFamilyOutdoor spaces

Corte Zuccaro, private pool, and courtyard
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Masseria Gemini, a XVIII century luxury retreat
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M&G Suite Home
FamilyLocationDecor

Casa Santapietra
LocationFamilyCheck-in
Weekly house rentals

Tricase Porto, beautiful with access to the sea
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House ANEMONE on the beach
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Helena · Nell’anima del centro storico di Lecce
FamilyLocationSleep quality

An intimate nest for two
LocationCleanlinessGetting around

Holiday home 'Della mia felicità'
LocationFamilyCheck-in

Seaside villa in Porto Cesareo
LocationFamilyGetting around

The Anchor
ValueLocationParking

Fabulous historic Palazzetto breathtaking seaview
LocationFamilyParking
Private house rentals

Coniger4 historic center of Lecce with Wi-Fi and Smart TV
LocationFamilyGetting around

Villa with Garden 300 meters from the sea
FamilyLocationWifi

The Roof House - Relaxing Home w/Private Veranda
LocationGetting aroundIndoor spaces

24 May Apartment
ValueFamilyIndoor spaces

Oasi Sul Mare in Castro
FamilyLocationView

Casa i Due Noci
LocationFamilyView

Small residence in Salento
LocationQuietWalkability

Villa with private access to the sea
LocationFamilyGrill
When is the best time to visit Sant'Isidoro?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$14,644 GYD | G$14,644 GYD | G$14,435 GYD | G$15,899 GYD | G$15,690 GYD | G$16,945 GYD | G$17,991 GYD | G$24,267 GYD | G$15,899 GYD | G$14,435 GYD | G$14,435 GYD | G$14,853 GYD |
| Avg. temp | 8°C | 9°C | 11°C | 14°C | 18°C | 23°C | 26°C | 26°C | 22°C | 18°C | 14°C | 10°C |
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- Salento
- Spiaggia Di Pescoluse
- Trulli Valle d'Itria
- Baia Dei Turchi
- Punta della suina
- Punta Prosciutto Beach
- Torre Guaceto Beach
- Torre San Giovanni Beach
- Togo bay la Spiaggia
- Spiaggia Le Dune
- Lido Morelli - Ostuni
- MAR.TA Museo Archeologico Nazionale di Taranto
- Spiaggia di Montedarena
- Porta Napoli
- Porto Selvaggio Beach
- Spiaggia Sant'Isidoro
- Castello Aragonese
- Cala dell'Acquaviva
- Roman Amphitheatre
- Dune Di Campomarino
- Torre di Porto Miggiano
- Splash Parco Acquatico
- Parco naturale regionale Dune costiere da Torre Canne a Torre S.Leonardo
- Sant'Andrea and Litorale di Punta Pizzo Regional Nature Park





