
House vacation rentals in Sant'Isidoro
Find and book unique houses on Airbnb
Quick stats about house rentals in Sant'Isidoro

Total vacation rentals
Explore 40 vacation rentals in Sant'Isidoro

Nightly prices starting at
Sant'Isidoro vacation rentals start at G$10,459 GYD per night before taxes and fees

Verified guest reviews
Over 110 verified reviews to help you choose

Family-friendly vacation rentals
20 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 20 rentals that welcome pets

Wi-Fi availability
10 of Sant'Isidoro vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Sant'Isidoro rentals

4.6 Average rating
Sant'Isidoro stays receive an average rating of 4.6 out of 5 from guests
Top-rated house rentals in Sant'Isidoro
Guests agree: these houses are highly rated for location, cleanliness, and more.

Private pool in Lecce, steps from old town
The pool is exclusively for you! Your small private oasis in the heart of Lecce. Relax in our lush garden, take a dip in your private pool, and enjoy a home-cooked meal with a glass of wine. Free parking is right in front the door. We provide everything for a perfect stay: toys, beach & pool essentials, umbrellas, sarongs, all cooking utensils, and speakers for your music on the terrace. A short walk takes you to Lecce’s historic center, and Salento’s stunning beaches are just 30 minutes away.
LocationFamilyBathroom

La Casa di Celeste - Apartment with terrace
La Casa di Celeste is a delightful newly renovated apartment in the historic center of Lecce. Located in a pedestrian area, a stone's throw from restaurants and cocktail bars that animate the city, it is perfect for 2 people, small families or couples of friends. It consists of a double bedroom, a room with a sofa bed, a living room, a kitchen, a bathroom and a large terrace with a barbecue where you can dine with maximum privacy and from which you can enjoy a beautiful view of the square.
FamilyLocationBathroom

Oasi Gorgoni Charming House & Pool
Lussuoso e confortevole appartamento, a ridosso del centro della città, ideale per godersi il relax, la città e il mare. Dotato di ogni comfort (3 camere, 3 bagni, living, piscina privata, giardino, Wi-Fi, aria condizionata, lavatrice, biancheria, stoviglie, parcheggio privato), l’appartamento è situato in uno dei quartieri più tranquilli e sicuri di Lecce. A soli 10 min. dal mare, consente di raggiungere facilmente sia la costa costa adriatica (Otranto), che la costa ionica (Gallipoli).
LocationFamilyBeach

Hélène Luxury Home Suite
Very central Luxury Home Suite! 100-square-meter Lecce stone residence in the historic center of LECCE. Suite HÉLÈNE is beautiful under starry vaults, minimal elements and modern touches. Lights and shadows in a dreamlike dimension! Services for a high-level stay: Relax in the small patio, comfort in its spaces and fabrics, regenerating bath in the majestic stone tub, heated floor, fully immersed in the sound diffused by a "full-sound" system: Style, Art, Love, Relaxation, Luxury...
LocationValueBeach

An intimate nest for two
An intimate nest for two in the historic center of Nardò. Created with love by a couple of architects who are passionate about everything Italian, this exclusive retreat is located within the ancient walls of Nardò and offers an elegantly furnished and landscaped panoramic terrace and a tower overlooking the castle's botanical garden. The sleeping area is immersed in the quiet historic center, while the rest of the house faces the lively Via Roma, convenient to services and parking.
LocationIndoor spacesWalkability

Historic residence in the center of Lecce, panoramic terrace
LA BORBONICA is a meticulously restored 19th-century residence transformed into an exclusive vacation home, where baroque dialogues with contemporary design. We are located in the heart of the historic center, among the most evocative streets of the city. This 110-square-meter apartment offers an immersive Salento experience, combining historical authenticity and modern comfort through handcrafted details and premium amenities. We are on the 1st floor, so it is very bright.
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Gallipoli Charming House, old town, sea view.
Forget your rhythm and stress in this peaceful space. It will let you taste the fishing village life and the Italian summer nights with little fish restaurants, bars and craft boutiques. You can relax yourself by reading a book at the fist floor and hearing local voices and dialects or admire the sunrise, sunset and the Faro di Sant’Andrea from the second top floor terrace. Purità beach at 200 mts walking. Oubliez le stress de tous les jours dans cet espace paisible.
LocationValueAir conditioning

On Caletta dell'Acquaviva, 20 meters from the sea.
The house "Perla dell 'Acquaviva" , in the middle of the Otranto-Leuca natural park , offers an enviable private access to the sea and the privilege of entering the waters of the cove through a comfortable rocky staircase different from the other bathers. The property consists of bathroom, bedroom, kitchen-living room, porch overlooking the sea. You will be welcomed by large outdoor spaces with a relaxation area among tall trees and the relaxing roar of the waves.
FamilyLocationParking

Exceptional house right on the beach.
° A two level house right on the beach. ° Terrace only a couple of meters from the sea. ° Modern design, new amenities, beautifully furbished. ° Ideally located to visit the jewels of the Salento, Italy's heel. ° Spectacular beach in seaside town. Desolate in winter. Great fun in high season. ° 55' from Brindisi Airport. ° Thomas and Els used to be the owners of another very appreciated holiday home. The older comments you'll read here are about that place.
FamilyLocationBathroom

Casa Florean - Historic Center of Lecce
Casa Florean is a 19th century house located in the historic center, the typical vaults and the local stone walls of Lecce transform the permanence into an immersive experience in the past and in the tradition of Salento. The period furnishings have been carefully chosen to maintain the style of typical Lecce houses and modern comforts. Our dream is to offer guests an unforgettable stay in one of the most beautiful and monumental baroque cities in Italy.
FamilyValueCheckout

Nonna Maria
Alloggio tradizionale finemente ristrutturato, immerso nella tranquillità della campagna Salentina. Situato in posizione strategica tra Lecce, Gallipoli, Otranto e le splendide spiagge della costa ionica. Offre ambienti accoglienti con dettagli autentici e comfort moderni. All’esterno, un ampio giardino curato ideale per rilassarsi dopo una giornata al mare o in escursione. Perfetto per chi cerca charme, natura e comodità.
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Holiday Home with swimming pool a stone's throw from Lecce PT
Located within a historic Salento palazzo, this independent and comfortable ground-floor home offers an authentic experience in the heart of southern Italy. A spacious terrace, equipped with a hot tub and solarium, provides the perfect setting for moments of true relaxation. The outdoor areas – including a private courtyard and panoramic terraces – are ideal for al fresco dining and enjoying the warm Salento atmosphere.
FamilyLocationHospitality
Popular amenities for Sant'Isidoro house rentals
House rentals with a pool

Casa Santapietra
LocationFamilyAmenities

Villa I 2 Leoni - Apartment 4 km from Lecce
LocationFamilyOutdoor spaces

Casa Shirocco Private Pool & Salento Charm
LocationFamilyBathroom

Villa Meraviglia
FamilyLocationKitchen

Dimora Disea
FamilyLocationBathroom

Lamia del Vespro. For families with children
FamilyLocationWifi

villa le ozze
LocationFamilyLong stay

Masseria Gemini, a XVIII century luxury retreat
LocationFamilyIndoor spaces
Weekly house rentals

U Palazzu de Tuie - Valentina's Houses
LocationConditionBeach

Villa near the sea
ValueFamilyCondition

House ANEMONE on the beach
FamilyLocationBathroom

Terrace overlooking the Duomo · Baroque Heart of Lecce
LocationFamilyDecor

Casa Zia Pina in the historic center of Nardò
LocationValueView

Fabulous historic Palazzetto breathtaking seaview
FamilyLocationBathroom

Casina Mameli
LocationValueNearby

Beautiful villa with a sea view.
FamilyLocationWalkability
Private house rentals

Small Residence in Salento
LocationHospitalityIndoor spaces

24 May Apartment
LocationFamilyLaundry

Le Scalere Salento
LocationFamilyOutdoor spaces

Amazing seafront attic with private terrace
LocationValueAccess

Corte Zuccaro, private pool, and courtyard
LocationFamilyAccess

Sea View Home Salento (200 m from the Sea)
LocationFamilySleep quality

Melville House, beachfront
LocationGrillComfort

Elegant Seafront House, Direct Access - Salento
FamilyLocationCondition
When is the best time to visit Sant'Isidoro?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$14,642 GYD | G$14,642 GYD | G$14,433 GYD | G$15,897 GYD | G$15,688 GYD | G$16,943 GYD | G$17,989 GYD | G$24,264 GYD | G$15,897 GYD | G$14,433 GYD | G$14,433 GYD | G$14,851 GYD |
| Avg. temp | 8°C | 9°C | 11°C | 14°C | 18°C | 23°C | 26°C | 26°C | 22°C | 18°C | 14°C | 10°C |
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- Salento
- Spiaggia Di Pescoluse
- Trulli Valle d'Itria
- Baia Dei Turchi
- Punta della suina
- Punta Prosciutto Beach
- Torre Guaceto Beach
- Torre San Giovanni Beach
- Togo bay la Spiaggia
- Spiaggia Le Dune
- Lido Morelli - Ostuni
- MAR.TA Museo Archeologico Nazionale di Taranto
- Porta Napoli
- Spiaggia di Montedarena
- Porto Selvaggio Beach
- Spiaggia Sant'Isidoro
- Gate Of Saint Blaise
- Castello Aragonese
- Dune Di Campomarino
- Cala dell'Acquaviva
- Parco naturale regionale Dune costiere da Torre Canne a Torre S.Leonardo
- Roman Amphitheatre
- Torre di Porto Miggiano
- Splash Parco Acquatico





