
House vacation rentals in Santiago Centro
Find and book unique houses on Airbnb
Quick stats about house rentals in Santiago Centro

Total vacation rentals
Explore 260 vacation rentals in Santiago Centro

Verified guest reviews
Over 7,290 verified reviews to help you choose

Family-friendly vacation rentals
40 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 40 rentals that welcome pets

Vacation rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
120 properties have a dedicated workspace

Wi-Fi availability
240 of Santiago Centro vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Santiago Centro rentals

4.8 Average rating
Santiago Centro stays are highly rated by guests—averaging 4.8 out of 5!

Nearby attractions
Santiago Centro's top spots, include Plaza de Armas of Santiago, Patio Bellavista, and Parque Forestal
Top-rated house rentals in Santiago Centro
Guests agree: these houses are highly rated for location, cleanliness, and more.

House for 5 people • 2 bathrooms • Large garden • A/C • 2 parking spaces
House for 5 people with 2 bedrooms + living room: 1 double bed, 3 single beds. Comfortable and functional 2-story house, fully equipped for large groups. The star attraction is the 90 m² private garden: safe for children, perfect for barbecues, and overlooking the mountain range. It includes hot/cold AC and 2 parking spaces inside. Smoking is prohibited inside the accommodation; there is a $100 fine for using the air conditioning. Located in La Florida with a bus stop 30 meters away. Close to Estadio Bicentenario and Florida Outlet.

Modern and Cozy House in Barrio Italia
Charming house in a small condominium, located in a quiet neighborhood, away from the noise but close to everything. A few minutes walk from Barrio Italia, a very attractive area, famous for its bohemian and cozy atmosphere, full of cafes, restaurants, ice cream parlors and designer, art and antique shops. There are bakeries, supermarkets and restaurants in the surrounding area, all within walking distance of the house. An ideal location to enjoy local life with comfort and tranquility. Perfect for family.

Guest House Italia Neighborhood
Charming mid-century independent duplex carefully restored to refresh its original beauty and enhance its comfort. It is quiet as it is surrounded by vegetation, far away from the street, and has double glazed windows, which improves acoustics and insulation. Located in the center of Barrio Italia, a vibrant commercial area, full of restaurants, trendy stores and antique shops. 7 minutes’ walking distance to the subway and 2 min to nearest bus station. Ubers are readily available.

House Boutique, Pablo Neruda, Providencia 1 Neighborhood
Beautiful house located in the heart of the Providencia commune, a private residential area, with 24/7 private security. The house is located in front of the museum of the great Chilean poet Pablo Neruda, who in 1953 began building a house in Santiago for Matilde Urrutia, his then secret love. In her honor he named it “La Chascona”, which was the nickname he gave her because of her abundant red hair. House Boutique is located right in front of La Chascona on Chucre Manzur Street.

Mahia House, Las Condes
Mahia House offers accommodation with free WiFi in Santiago near supermarkets and shops, steps from the Los Dominicos Mall, Parks, special to enjoy as a family. A 10-minute walk to the Los Dominicos metro station and the famous Pueblito Los Dominicos. The location is fantastic, Las Condes is a safe and wooded neighborhood. My family and I live in the "upstairs house" and we will always be attentive to what you need to make your stay literally at home and local. Welcome!!!

Spacious 5-Bedroom House • 12 Beds • 14 People
Spectacular 2-story house in a condominium with parking for 3 vehicles, private barbecue grill and pool. 1st floor: - BD with a king bed and a private BA with a shower - BD with a bunk bed - Kitchen - Living and dining room 2nd floor: - A BD with a double bed and a twin bed - BD with a pull-out bunk bed and 1 single bed - BD with a trundle bed and a twin bed - BA with shower Patio with barbecue area, pool and outdoor BA Fully equipped house with sheets and towels

Casa Laberinto: wellness space
Casa Laberinto is a unique space for rest and relaxation in the middle of Santiago. Designed to offer a calm and wellness experience, it combines a large private patio for relaxing, traveling with your pet and working. Located in a quiet residential neighborhood of Providencia, which allows you to enjoy the city with easy access to cafes, restaurants and services, while maintaining a quiet and safe environment. It includes indoor parking with independent access.

Large house located in the foothills of the Andes
Enjoy this Mediterranean-style home nestled in the Andes Mountains. This 200 m² property sits on a large lot with sweeping panoramic views of Santiago. With nearby parks and playgrounds, and on-site parking, it's ideal for families with children and pets. It's conveniently located near Starbucks, Shopping Malls, the Bahá'í Temple, and Panul Park, perfect for enjoying nature. Enjoy barbecues in the covered outdoor kitchen with family and friends. Don't miss out!

Independent House/Annex with Private Patio
A peaceful and completely private place in Santiago. Enjoy Santiago from a comfortable and quiet independent apartment, ideal for relaxing after exploring the city. Located in a safe residential neighborhood, with a private patio and excellent access to the Plaza Egaña and Simón Bolívar metro stations, and a shopping mall with essential services. Perfect for small families, couples, or business travelers seeking tranquility without being far from everything.

Casa El Golf · Exclusive and Safe Neighborhood
Enjoy a luxury experience in Las Condes. This exclusive residence offers spacious heated spaces, an equipped kitchen, high-standard bedrooms (including a suite with a king-size bed), and a private pool, perfect for relaxing in total privacy. Located in a safe area next to the U.S. Embassy, with easy access to restaurants, boutiques, shopping malls, and cultural attractions. Ideal for business or pleasure trips. An exceptional stay awaits you.

Exclusive hideaway in La Dehesa
Escape to this unique house in La Dehesa, located on a large plot of land surrounded by nature. Enjoy total privacy with all the amenities you need, spacious spaces and a quiet environment, ideal for disconnecting and relaxing. It also has great connectivity with the Costanera Norte and important shopping centers in the city. The house is fully equipped, has a Smart TV, air conditioning, parking, a gas BBQ and a nice garden.

Large Family House (5D) Quincho-Pool-Las Condes
Amazing 5-bedroom house in the best sector of Las Condes. Enjoy a patio with a pool, a designer barbecue, a private gym, and integrated spaces. Privileged location just 10 minutes (1 km) walk to the Hernando de Magallanes Metro, 200 meters from ski shops, other shops and restaurants. 1.6 km from the Alto Las Condes Mall and 2.6 km from the Plaza Los Dominicos mall. Everything within walking distance!
Popular amenities for Santiago Centro house rentals
House rentals with a pool

House for groups | Pool, patio and grill | 4 cars

House in Quinchamali Sport Mall / La Dehesa Entrance

House in Vitacura 12 people pool snow shopping clinics

House for large groups with all the amenities

Nice and safe house in Las Condes: BBQ and Pool

Santiago Family House

Private Tiny House in Santiago whit HotTube

Las Condes House Padre Hurtado Mall Alto Las Condes
Weekly house rentals

Depto.Interior/Estacionamiento Private/Metro Steps

Guest house with a private garden.

House in El Golf area - Tobalaba

Nice house w/garden & heating in Las Condes

1 Gasparinn Apartment in the best neighborhood of Santiago

Casa Bonsai, a unique space to enjoy

Beautiful house in Ñuñoa

House located in the heart of the Italia neighborhood
Private house rentals

Comfortable, cozy house in a very good location.

Charming House in Vitacura with Private Garden

E1.0 Casa EstadioBicentenario Groups Large patio

Casona Providencia, over 20 people / Patio / Grill / Café

Beautiful and cozy house + parking + patio

A very well located house, close to the subway and the mall

Casa Cascal

Isolated house in Renca near the airport
When is the best time to visit Santiago Centro?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$5,646 GYD | G$5,646 GYD | G$5,228 GYD | G$5,437 GYD | G$5,646 GYD | G$5,437 GYD | G$5,437 GYD | G$5,019 GYD | G$5,228 GYD | G$5,437 GYD | G$5,228 GYD | G$5,646 GYD |
| Avg. temp | 22°C | 21°C | 20°C | 16°C | 13°C | 10°C | 10°C | 11°C | 13°C | 16°C | 19°C | 21°C |
Destinations to explore
- Providencia Vacation rentals
- Viña del Mar Vacation rentals
- Las Condes Vacation rentals
- Ñuñoa Vacation rentals
- Concepción Vacation rentals
- Concón Vacation rentals
- Valparaíso Vacation rentals
- Mendoza Vacation rentals
- Maitencillo Vacation rentals
- La Florida Vacation rentals
- Algarrobo Vacation rentals
- La Serena Vacation rentals
- Loft rentals Santiago Centro
- Private suite rentals Santiago Centro
- Rentals with a hot tub Santiago Centro
- Rentals with beach access Santiago Centro
- Rentals with pools Santiago Centro
- Serviced apartment rentals Santiago Centro
- Family-friendly rentals Santiago Centro
- Guesthouse rentals Santiago Centro
- Boutique hotels Santiago Centro
- Hotel rooms Santiago Centro
- Hostel rentals Santiago Centro
- Bed and breakfasts Santiago Centro
- Rentals with breakfast Santiago Centro
- Rentals with a sauna Santiago Centro
- Vacation home rentals Santiago Centro
- Pet-friendly rentals Santiago Centro
- Rentals with an accessible height bed Santiago Centro
- Apartment rentals Santiago Centro
- Condo rentals Santiago Centro
- House rentals Santiago Metropolitan Region
- House rentals Chile
- Valle Nevado Ski Resort
- La Parva
- Farellones
- Estadio Nacional Julio Martinez Pradanos
- Costanera Center
- Parque Arauco
- Estadio Bicentenario La Florida
- Escuela Militar
- Sky Costanera
- Teatro Caupolican
- Termas Valle De Colina
- La Moneda Palace
- El Colorado
- Los Leones
- Fantasilandia
- Plaza Ñuñoa
- Plaza de Armas of Santiago
- Monticello Grand Casino
- Fundación Arturo López Pérez Falp
- Mall Plaza Egaña
- Plaza Baquedano
- Clarillo River
- Viña Concha Y Toro
- Parque Inés de Suárez
- Things to do Santiago Centro
- Art and culture Santiago Centro
- Nature and outdoors Santiago Centro
- Sightseeing Santiago Centro
- Food and drink Santiago Centro
- Tours Santiago Centro
- Things to do Santiago Metropolitan Region
- Art and culture Santiago Metropolitan Region
- Nature and outdoors Santiago Metropolitan Region
- Tours Santiago Metropolitan Region
- Sightseeing Santiago Metropolitan Region
- Food and drink Santiago Metropolitan Region
- Sports activities Santiago Metropolitan Region
- Things to do Chile
- Tours Chile
- Art and culture Chile
- Sports activities Chile
- Food and drink Chile
- Nature and outdoors Chile
- Sightseeing Chile







