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House vacation rentals in Santiago Centro

Find and book unique houses on Airbnb

Quick stats about house rentals in Santiago Centro

  • Total vacation rentals

    Explore 260 vacation rentals in Santiago Centro

  • Verified guest reviews

    Over 7,290 verified reviews to help you choose

  • Family-friendly vacation rentals

    40 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 40 rentals that welcome pets

  • Vacation rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    120 properties have a dedicated workspace

  • Wi-Fi availability

    240 of Santiago Centro vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Santiago Centro rentals

  • 4.8 Average rating

    Santiago Centro stays are highly rated by guests—averaging 4.8 out of 5!

  • Nearby attractions

    Santiago Centro's top spots, include Plaza de Armas of Santiago, Patio Bellavista, and Parque Forestal

Top-rated house rentals in Santiago Centro

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Top guest favorite
Home in La Florida
4.94 out of 5 average rating, 165 reviews

House for 5 people • 2 bathrooms • Large garden • A/C • 2 parking spaces

House for 5 people with 2 bedrooms + living room: 1 double bed, 3 single beds. Comfortable and functional 2-story house, fully equipped for large groups. The star attraction is the 90 m² private garden: safe for children, perfect for barbecues, and overlooking the mountain range. It includes hot/cold AC and 2 parking spaces inside. Smoking is prohibited inside the accommodation; there is a $100 fine for using the air conditioning. Located in La Florida with a bus stop 30 meters away. Close to Estadio Bicentenario and Florida Outlet.

Superhost
Home in Providencia
5 out of 5 average rating, 3 reviews

Casa Espejo Loft

Beautifully restored Art Deco house from 1938 designed by the famous architect Luciano Kulczewski. The premises rests in the heart of Barrio Italia, a lively neighborhood full of bars restaurants and coffee shops, but the house is quiet as it is emplaced on a residencial street. The house a duplex loft with lots of original art deco details from the 30, including 3,7m ceilings in the kitchen, hard wood floors, art deco steel windows and doors. The house includes a private patio/garden.

Guest favorite
A dining table is set with plates and glassware, featuring a floral centerpiece of yellow calla lilies. The warm wood finish of the table contrasts with the light walls, while natural light filters in through a nearby window, enhancing the inviting ambiance of the space.
Home in Providencia
4.92 out of 5 average rating, 177 reviews

House Boutique, Pablo Neruda, Providencia 1 Neighborhood

Beautiful house located in the heart of the Providencia commune, a private residential area, with 24/7 private security. The house is located in front of the museum of the great Chilean poet Pablo Neruda, who in 1953 began building a house in Santiago for Matilde Urrutia, his then secret love. In her honor he named it “La Chascona”, which was the nickname he gave her because of her abundant red hair. House Boutique is located right in front of La Chascona on Chucre Manzur Street.

Guest favorite
Home in Providencia
4.84 out of 5 average rating, 58 reviews

House located in the heart of the Italia neighborhood

House located in the heart of the Italia neighborhood (providencia), with a patio, very central, close to bars, restaurants, 50 meters from Tottus supermarket, Bustamante park metro station 4 blocks away, bus stop 50 meters away. Fully equipped kitchen, electric oven, microwave, gas stove, minibar, pots, kitchen utensils, kitchen towels, hot water with electric thermos, full bathroom, shower and hand towels. Bed with sheets and bedding. Electric stove, Wi-Fi. Electric blanket.

Guest favorite
A modern living area features a blue couch and an armchair, complemented by decorative throw pillows. Two small coffee tables sit in front, while a wooden cabinet and wall-mounted shelves with plants and art pieces enhance the ambiance. Natural light filters through sheer blinds.
Home in Las Condes
4.82 out of 5 average rating, 169 reviews

Mahia House, Las Condes

Mahia House offers accommodation with free WiFi in Santiago near supermarkets and shops, steps from the Los Dominicos Mall, Parks, special to enjoy as a family. A 10-minute walk to the Los Dominicos metro station and the famous Pueblito Los Dominicos. The location is fantastic, Las Condes is a safe and wooded neighborhood. My family and I live in the "upstairs house" and we will always be attentive to what you need to make your stay literally at home and local. Welcome!!!

Guest favorite
Home in La Florida
4.92 out of 5 average rating, 221 reviews

Spacious 5-Bedroom House • 12 Beds • 14 People

Spectacular 2-story house in a condominium with parking for 3 vehicles, private barbecue grill and pool. 1st floor: - BD with a king bed and a private BA with a shower - BD with a bunk bed - Kitchen - Living and dining room 2nd floor: - A BD with a double bed and a twin bed - BD with a pull-out bunk bed and 1 single bed - BD with a trundle bed and a twin bed - BA with shower Patio with barbecue area, pool and outdoor BA Fully equipped house with sheets and towels

Guest favorite
A serene outdoor space is shown, featuring a rectangular swimming pool surrounded by neatly trimmed greenery. An adjacent area is highlighted with well-maintained grass, while a patio area with seating can be seen in the background, enhancing the ambiance.
Home in Las Condes
4.89 out of 5 average rating, 81 reviews

Large Family House for Resting Home Office x 7

Enjoy a stay at Casa Las Condes! This spacious and modern family home offers the perfect combination of tranquility and rest with a large terrace, pool, barbecue and surrounded by trees, plaza and nature. Very cozy, home warmth in winter with a Bosca stove, ideal for families with children, Home Cinema living room, large fully equipped kitchen, countertop, dishwasher and more. Master bedroom with en-suite bathroom + air conditioning. Bicycles to explore. Parking

Superhost
Home in Providencia
4.97 out of 5 average rating, 29 reviews

Casa Laberinto: wellness space

Casa Laberinto is a unique space for rest and relaxation in the middle of Santiago. Designed to offer a calm and wellness experience, it combines a large private patio for relaxing, traveling with your pet and working. Located in a quiet residential neighborhood of Providencia, which allows you to enjoy the city with easy access to cafes, restaurants and services, while maintaining a quiet and safe environment. It includes indoor parking with independent access.

Top guest favorite
Home in La Florida
4.98 out of 5 average rating, 110 reviews

Large house located in the foothills of the Andes

Enjoy this Mediterranean-style home nestled in the Andes Mountains. This 200 m² property sits on a large lot with sweeping panoramic views of Santiago. With nearby parks and playgrounds, and on-site parking, it's ideal for families with children and pets. It's conveniently located near Starbucks, Shopping Malls, the Bahá'í Temple, and Panul Park, perfect for enjoying nature. Enjoy barbecues in the covered outdoor kitchen with family and friends. Don't miss out!

Superhost
Home in Providencia
5 out of 5 average rating, 4 reviews

8-person house in Providencia, A/C and private parking

Casona independiente de dos pisos en pleno Providencia, a dos cuadras del metro Pedro de Valdivia y rodeada de restaurantes, parques y comercio. Tiene 120 m2, 4 dormitorios y 2,5 baños para hasta 8 personas, con dos livings y comedor para 8. Suma aire acondicionado frío-calor, estacionamiento privado tras portón, Smart TV y buen WiFi. Una casa completa con carácter en un barrio de puros departamentos: ideal para familias o grupos en viajes de trabajo o turismo.

Top guest favorite
Home in La Reina
4.96 out of 5 average rating, 107 reviews

Independent House/Annex with Private Patio

A peaceful and completely private place in Santiago. Enjoy Santiago from a comfortable and quiet independent apartment, ideal for relaxing after exploring the city. Located in a safe residential neighborhood, with a private patio and excellent access to the Plaza Egaña and Simón Bolívar metro stations, and a shopping mall with essential services. Perfect for small families, couples, or business travelers seeking tranquility without being far from everything.

Guest favorite
A private terrace features two lounge chairs facing a glimmering pool, designed for relaxation. Lush greenery surrounds the area, creating a tranquil setting. Large glass doors reflect the sunlight and offer glimpses of the interior space. The ambiance highlights a seamless connection with nature.
Home in Las Condes
4.91 out of 5 average rating, 34 reviews

Casa El Golf · Exclusive and Safe Neighborhood

Enjoy a luxury experience in Las Condes. This exclusive residence offers spacious heated spaces, an equipped kitchen, high-standard bedrooms (including a suite with a king-size bed), and a private pool, perfect for relaxing in total privacy. Located in a safe area next to the U.S. Embassy, with easy access to restaurants, boutiques, shopping malls, and cultural attractions. Ideal for business or pleasure trips. An exceptional stay awaits you.

Popular amenities for Santiago Centro house rentals

When is the best time to visit Santiago Centro?

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Avg. priceG$5,624 GYDG$5,624 GYDG$5,207 GYDG$4,999 GYDG$5,207 GYDG$5,415 GYDG$5,415 GYDG$4,999 GYDG$5,207 GYDG$5,415 GYDG$5,207 GYDG$5,624 GYD
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