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Apartment vacation rentals in Santiago Centro

Find and book unique apartments on Airbnb

Quick stats about apartment rentals in Santiago Centro

  • Total vacation rentals

    Explore 8,440 vacation rentals in Santiago Centro

  • Verified guest reviews

    Over 276,070 verified reviews to help you choose

  • Family-friendly vacation rentals

    1,780 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 2,460 rentals that welcome pets

  • Vacation rentals with a pool

    3,190 properties feature pools

  • Rentals with dedicated workspaces

    3,470 properties have a dedicated workspace

  • Wi-Fi availability

    8,200 of Santiago Centro vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Santiago Centro rentals

  • 4.7 Average rating

    Santiago Centro stays receive an average rating of 4.7 out of 5 from guests

  • Nearby attractions

    Santiago Centro's top spots, include Plaza de Armas of Santiago, Patio Bellavista, and Parque Forestal

Top-rated apartment rentals in Santiago Centro

Guests agree: these apartments are highly rated for location, cleanliness, and more.

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Guest favorite
A compact studio kitchen is equipped with modern appliances, including a microwave and electric kettle. A dining table with chairs occupies the space, while light enters from a large window overlooking greenery. A mirror adds depth, complementing the streamlined cabinetry and cozy sleeping area.
Apartment in Yungay
4.97 out of 5 average rating, 226 reviews

Studio in Quinta Normal Park

Cozy and quiet studio with a fully equipped kitchen and air conditioning in the summer season, ideal for a comfortable stay in Santiago. Just steps from Parque Quinta Normal and close to the Gruta de Lourdes and Quinta Normal metro stations, with excellent transport connections. Close to Matucana 100, museums, the hospital, the Santiago Library, shops, and the Autopista Central highway. Just 20 minutes from the airport. The building has an elevated plaza overlooking the park and the Basilica of Lourdes. Parking available.

Guest favorite
An inviting dining area is highlighted by a central round light fixture and warm wall tones. A spacious wooden table with chairs is positioned near textured windows. Art pieces adorn the walls, and a well-organized kitchen area is visible in the background.
Apartment in Santiago
4.87 out of 5 average rating, 165 reviews

Lastarria Penthouse, Amazing Terrace

Unwind on the terrace every morning while sipping a cup of coffee, with amazing views of the city and Cerro San Cristóbal. Enjoy the modern and vintage charm of this beautiful space in the heart of Lastarria, surrounded by original art and exquisite design. *IMPORTANT: Check-in Window is from 3pm until 8pm Lastarria is one of the most beautiful districts in Santiago. You can take beautiful walks around Parque Forestal and Bellas Artes Museum which is only two blocks away from the penthouse.

Guest favorite
A bright living area features large windows that provide natural light and views of the surrounding city. A comfortable white sofa with decorative pillows sits adjacent to a glass coffee table. Indoor plants are placed near the windows, creating a fresh and inviting environment.
Apartment in Santiago
4.93 out of 5 average rating, 147 reviews

Santiago Chile Downtown Apartment in Bellas Artes

Ubicado en el corazón de Santiago, a pasos del Metro Bellas Artes, y cuadras de los lugares más turísticos de Santiago. Mosqueto es una calle cortita llena de vida! Esta rodeada de pubs y restaurants, cercano de los barrios con más cultura y diversidad en Santiago. Depto de 8 pisos, living ,comedor, cocina, 1 baño, 1 dormitorio, 1 cama, terraza , wifi, cable. Muy limpio y acogedor ! Mágico para turistas que quieren pasar unos días en el punto cero, en el Casco antiguo de Santiago de Chile.

Top guest favorite
The open living area features a wooden beam ceiling and a blend of modern and classic furnishings. A glass coffee table sits on a decorative rug, with a light blue sofa adjacent. A dining area with white chairs and a stylish light fixture is visible in the background.
Apartment in Providencia
4.94 out of 5 average rating, 88 reviews

Apartment in Providencia, Costanera Center

We invite you to visit our apartment "Cata Musalem" located in THE ATTIC OF THE THIRD FLOOR of a beautiful French-style mansion. You will stay in a large space of classic and elegant architecture that is located in a residential and quiet area very close to the "Mall Costanera Center" and the metropolitan park, on the north bank of the Mapocho River. It will be ideal for your vacation/work stay in Santiago due to its beautiful surroundings and high transport connectivity.

Guest favorite
A scenic view is presented from the balcony, showcasing the hill of San Cristóbal against a twilight sky. The vibrant cityscape is complemented by the illuminated buildings below, with trees and outdoor seating areas visible in the foreground.
Apartment in Santiago
4.8 out of 5 average rating, 188 reviews

Nice views in Lastarria with a king-size bed

Enjoy Santiago from our comfortable and bright apartment, featuring stunning views of San Cristóbal Hill and the Andes Mountains. Located in the heart of the Lastarria neighborhood, just steps from Universidad Católica metro station, and surrounded by museums, theaters, bars, and restaurants. Ideal for those seeking culture, history, and vibrant city life. Perfect for travelers who value great location, cozy design, and an authentic experience in the city’s cultural hub.

Guest favorite
Apartment in Las Condes
4.94 out of 5 average rating, 646 reviews

AT HOME El Golf Apartment 3 rooms

Wake up in the exclusive El Golf district. Spacious, bright, and fully equipped apartments. Featuring three bedrooms (master en-suite), an open-plan living and dining area, a fully equipped kitchen, and a separate lounge ideal for a home office. Enjoy fully autonomous access, high-speed WiFi, and impeccable cleaning standards. Located just steps from the Metro, and surrounded by top restaurants, cafés, parks, and everything you need to move around Santiago with ease.

Top guest favorite
A comfortable sleeping area is showcased, featuring a spacious bed adorned with neutral-colored bedding. Two bedside lamps provide soft lighting, while potted plants enhance the natural feel of the room. A stylish area rug lies beneath the bed, complementing the warm wood tones of the floor.
Apartment in Santiago
4.99 out of 5 average rating, 148 reviews

Welcome to Santiago/metro Toesca

Disfruta de la comodidad que ¡Welcome to Santiago! tiene preparado para ti, conoce los lugares icónicos de la ciudad, estamos a 5 minutos del metro estación TOESCA, a 15 del Movistar Arena, a 10 del parque de diversiones Fantasilandia y a pasos del parque O'Higgins. Contamos con todo lo necesario para que tu estadía sea lo más cómoda posible, cocina, baño y living-comedor totalmente equipadas. Atención!! La temporada de piscina inicia el 24 de noviembre del 2025

Guest favorite
Apartment in Providencia
4.93 out of 5 average rating, 130 reviews

luxury place for 8 people steps from the metro

Welcome to Casa Ruka The perfect space to share in Santiago. This spacious luxury apartment (200 m²) in Providencia is designed for groups, families or trips with friends looking for comfort, location and a unique experience. 🛏 Capacity up to 8 people 📍 Privileged location Steps from the Salvador metro, in front of Cerro San Cristóbal and close to the main tourist neighborhoods of Santiago. 🛋 Spaces to share Living room, dining room and common areas

Guest favorite
An open-plan kitchen and dining area is visible, featuring a wooden dining table surrounded by green and wire-framed chairs. The modern kitchen includes light cabinetry and stainless steel appliances. A potted plant adds a touch of greenery to the space, enhancing its bright ambiance.
Apartment in Santiago
4.92 out of 5 average rating, 106 reviews

Apartment in Barrio Lastarria

Beautiful and bright newly remodeled apartment located in Barrio Lastarria, a bohemian place full of culture, art and food. The location is ideal for discovering Santiago. It is just a 5-minute walk to the nearest metro station, close to the city's historic center, at the foot of Santa Lucía Hill, and close to parks and museums. Enjoy our cozy and modern apartment with an attractive design fully equipped for vacation or work.

Guest favorite
A bright living area is highlighted by large windows that offer panoramic views of the cityscape and surrounding hills. Modern furnishings include a comfortable sofa, stylish chairs, and a dining table with decorative accents. Natural light fills the space, creating an inviting atmosphere.
Apartment in Santiago
4.9 out of 5 average rating, 129 reviews

Spectacular apartment with panoramic views.

Charming apartment in the heart of Santiago with a stunning panoramic view of downtown. Enjoy the illuminated skyscrapers at night and urban landscapes during the day. This cozy space has modern amenities, elegant decor, and all the necessary amenities for an unforgettable stay. From the private balcony, you can enjoy panoramic views ranging from the mountain range to the city's landmarks.

Top guest favorite
A spacious bedroom features a comfortable bed adorned with a light green throw and neatly arranged towels. Natural light enters through large windows, illuminating a cozy seating area with a chair and small table. Two bedside lamps add subtle lighting to the room.
Apartment in Santiago
4.99 out of 5 average rating, 97 reviews

Nice renovated place with A/C in Lastarria. Ideal for travelers

This place is strategically located: it will be very easy to plan your visit! The apartment is designed so that you can sleep peacefully, safely and with all possible amenities. Lastarria neighborhood has various restaurants, cinema, theater, park, clinic and cultural centers. You can walk to the iconic places in downtown Santiago. Steps from the Universidad Católica metro.

Top guest favorite
Apartment in Ñuñoa
4.96 out of 5 average rating, 143 reviews

Apartment with View | A/C | Italia Neighborhood and Metro nearby

Enjoy a modern apartment on the 21st floor with spectacular views of Santiago, right across from the Irarrázaval metro station. Ideal for 2-3 people, this bright and fully equipped space is close to the vibrant Barrio Italia and the Estadio Nacional. Includes high-speed Wi-Fi, a work area, A/C, and access to the building's pool and gym. Perfect for work or leisure.

Popular amenities for Santiago Centro apartment rentals

When is the best time to visit Santiago Centro?

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Avg. priceG$8,156 GYDG$7,946 GYDG$7,737 GYDG$7,528 GYDG$7,528 GYDG$7,737 GYDG$7,946 GYDG$7,737 GYDG$7,528 GYDG$7,528 GYDG$7,737 GYDG$7,737 GYD
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