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Lake house vacation rentals in Santee

Find and book unique lake houses on Airbnb

Top-rated lake house rentals in Santee

Guests agree: these lake houses are highly rated for location, cleanliness, and more.

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Guest favorite
A scenic aerial view captures a vibrant neighborhood at sunset, with homes nestled on hills. A private pickleball court, marked in pink, can be seen next to a pool, while distant water bodies and colorful houses create a picturesque backdrop.
Home in Spring Valley
4.85 out of 5 average rating, 80 reviews

SD Lux Oasis: Theatre, Spa, 14Beds, AC, Sleeps 20+

SEND US MESSAGE FOR SPECIAL OFFER! Highlights: ⭐️14 beds/6bed/3.5bath ⭐️ Pickleball Court & Golf Course: Play a fun match on your private, stylish court! ⭐️Theater Room: Cozy up for a movie night w/ premium sound and luxurious seating.  ⭐️Classy Get-Ready Station: Perfect for preparing for events, complete with ample lighting and mirrors. ⭐️Sparkling Pool & Spa: Relax and unwind in the sun or under the stars. We have one ring camera outside the front door & you’ll be 18 min away from to downtown!

Guest favorite
A resort-style pool area is highlighted by a palm tree and soft lighting from string lights above. A pink flamingo float and beach balls rest in the clear water, showcasing a serene evening ambiance.
Home in La Mesa
4.95 out of 5 average rating, 37 reviews

Pool + Hot Tub, BBQ, Chef Kitchen, SDSU, San Diego

Unwind at this stylish home that sleeps 6, featuring a 👩‍🍳 chef’s kitchen, smart TVs, high-speed Wi-Fi, and a modern bathrooms. Outside, enjoy a resort-style private pool, propane grill, outdoor seating, and a 6-person hot tub nestled under a tree-covered gazebo. Located just minutes from SDSU 🎓 and 20 minutes from top San Diego attractions. With free parking , secure self-check-ins, and peaceful surroundings, this private retreat offers comfort and convenience. Book now and relax in style!

Top guest favorite
A private pool is framed by stone edges and palm trees, with a tranquil atmosphere at dusk. The setting sun casts soft colors over the water, highlighting the natural landscape beyond. Gathering areas and light fixtures are visible, enhancing the outdoor retreat.
Home in Oceanside
4.97 out of 5 average rating, 122 reviews

Private Oasis/Pool/Spa/Views/Near Beaches/Legoland

Spectacular views of Calavera Lake Preserve w/miles of scenic hiking trails directly out the back gate. Take a swim (heating optional) in lagoon-style pool, or spa in the private, resort-like backyard featuring fire pits, BBQ & cozy gathering areas. Conveniently located mins from Legoland, Frontwave Arena, Beaches, Eateries, Breweries, Wineries, Oceanside Pier & Harbor. Only 30(+) mins to World Famous San Diego Zoo, Balboa Park, Wild Animal Safari Park, SeaWorld, Old Town & Downtown San Diego.

Top guest favorite
The outdoor area features a cozy seating arrangement with two adirondack chairs around a gas camping-style fire pit. Tropical palm trees create a lush backdrop, while sliding glass doors provide access to the interior. The ambient lighting adds warmth to the space.
Home in Mission Beach
5 out of 5 average rating, 205 reviews

Steps To Beach! Family Friendly-Remote Office-Fire

House with Full-Size Car Garage, AC, private gas camping-style Fire in the Yard, 2 Patios, 2 Indoor Gas Fireplaces, Grill, & Laundry. 3 Bedrooms, 2 are primary with bathrooms, one with fireplace & kitchenette. Fully equipped Kitchen with outdoor Grill, just off the Dining area. Office Space plus fast 3 hub WiFi-6 coverage everywhere. 50 steps from the Beach or the Bay. Short ocean walk to PB with tons of restaurants & boutiques. Yelp lists 86 restaurants with 4-star+ reviews within easy walk.

Guest favorite
A tropical pool area is featured, showcasing a winding design with clear waters. A thatched gazebo and lush greenery surround the pool, and a water slide is visible cascading into the pool. Sunlight reflects off the surface, enhancing the tranquil environment.
Home in Scripps Miramar Ranch
4.96 out of 5 average rating, 125 reviews

Luxurious Home w/Hot Tub & Pool + Water Slide

Hosted by Benitt Rentals, this tropical oasis is located in the Waterford Scripps Ranch community. The house has a large & inviting pool, a terrific slide for kids, a hot tub & a builtin BBQ. It's a perfect place for a family to relax & enjoy all that San Diego has to offer. It's a couple of miles from the lake w/ beautiful views, jogging, biking, canoeing, etc. It's centrally located in San Diego, <30 minutes from most things including downtown, the beaches, the Wild Animal Park & more.

Top guest favorite
A comfortable living room features a gray sectional sofa arranged around a coffee table. A large TV is positioned against the wall, complemented by a minimalist wooden console. A rug enhances the space, while natural light enters through the windows, illuminating a decorative plant in the corner.
Home in Scripps Miramar Ranch
4.94 out of 5 average rating, 136 reviews

20% OFF- Newly updated guesthome for families

Newly updated peaceful and convenient guesthome in Scripps Ranch. With a private dining room, a fully equipped private kitchen, two cozy bedrooms with desks, and a private bathroom. With central AC and 500Mbp WIFI. 1 minute's driving to a plaza with a supermarket, bank, Starbucks, and restaurants. 5 minutes’ drive to Lake Miramar. Perfect location for exploring UCSD, LaJolla Shores, San Diego Zoo, Sea World, Legoland, Balboa Park, and many other attractions in San Diego.

Guest favorite
A lakefront home is framed by lush palm trees and vibrant greenery. Soft hues of sunset illuminate the structure's large windows, reflecting a serene ambiance. Swans glide gracefully on the water, enhancing the tranquil lakeside setting.
Home in Lake San Marcos
4.9 out of 5 average rating, 117 reviews

Lake House 1475 San Diego on the lake

Gorgeous San Diego lake resort, driving distance to the Ocean, 1.5 hours from Disneyland, 40 minutes from Sea World, 20 minutes from Wild Animal Park, 15 minutes from Legoland, 45 minutes from San Diego Zoo If you have a family this a great place to stay If you are a retired couple, this is a great place to stay If you are getting married and looking for an amazing place to have a wedding Lake San Marcos is a gorgeous venue and our house is very close to the resort

Top guest favorite
Home in Del Cerro
5 out of 5 average rating, 19 reviews

Surf to Skyline | 6BR Luxury Stay w/ Stunning View

Welcome to Surf to Skyline – Where luxury, nature, and city views unite. This newly remodeled 6-bedroom retreat sleeps 16+ and offers stunning views of San Diego and Lake Murray. With 3 full and 2 half baths, it’s perfect for families, couples, or large groups. Enjoy high-end finishes, spacious living, and unforgettable sunsets in a serene setting just minutes from everything. Whether you're relaxing on the deck or exploring the city – comfort and connection await.

Top guest favorite
Home in San Diego
4.97 out of 5 average rating, 66 reviews

5Bed•Heated Pool & Spa•2 Big Private Master Suites

Family home! Located in San Carlos, 8 min to SDSU, 18 min to 8 min to SDSU, 18 min to Mission Beach, 24 min to Coronado. Remodeled Oct 2025 with $500K+ in upgrades, this 5BR/3.5BA villa features a saltwater pool w/ Baja shelf, 12-person spa, theater w/ recliners, retro arcade, Peloton, fire pit & BBQ. Pool heat optional; spa included. Main house only; Guests enjoy exclusive use of home, pool, spa & yard. Three Synagogues within walk distance. No parties allowed.

Top guest favorite
Home in Lakeside
4.99 out of 5 average rating, 78 reviews

San Diego Family Oasis: Pool, Spa, Game & Fire Pit

Relax in your private pool & spa at The Birdhouse SD — a family-friendly 3-bedroom retreat with a resort-style backyard just 20 minutes from San Diego’s beaches, zoo, and downtown. Perfect for families and small groups, the home features 5 beds, a game room, indoor-outdoor living, BBQ, fire pit lounge, and a fully equipped kitchen. Enjoy fast Wi-Fi, smart TVs, and plenty of space to unwind after exploring Southern California.

Superhost
Home in Del Cerro
4.71 out of 5 average rating, 42 reviews

Lux Penthouse • Pool • Views • Sleep 20 • AC • Spa

SEND US A MESSAGE FOR SPECIAL OFFER! Imagine booking the most memorable experience with your BIG party! You can kick back in a safe & fun oriented experience! Check in contactless & enjoy! The cozy, modern space includes Pool, Spa, BBQ, Outdoor Games & 11 beds! You get 5 bedrooms, & 3 bathrooms, and and 2 separate modern kitchens. The entire house is 30 mins from the beach, 45 to the snow, & 30 mins from downtown.

Superhost
A bright living area is highlighted by large windows and light-colored walls. A brown leather sofa is positioned adjacent to a light coffee table. A modern armchair and a floor lamp complement the space, with greenery visible outside the glass doors.
Home in National City
4.88 out of 5 average rating, 130 reviews

Modern Comfy 2B2B | Close to Downtown | Fast Wi-Fi

Enjoy a stylish experience at this centrally-located place close to Downtown San Diego. Modern two bedroom and two bathroom with backyard and two car garage with luxurious amenities throughout. Less than 6 miles away from Downtown San Diego. — minutes away from the beach, Downtown/Gaslamp, SeaWorld, SD Zoo, Balboa Park, shopping center, restaurants, SDSU, and UCSD.

Popular amenities for Santee lake house rentals