
House vacation rentals in Santee
Find and book unique houses on Airbnb
Quick stats about house rentals in Santee

Total vacation rentals
Explore 50 vacation rentals in Santee

Nightly prices starting at
Santee vacation rentals start at G$8,373 GYD per night before taxes and fees

Verified guest reviews
Over 1,440 verified reviews to help you choose

Family-friendly vacation rentals
30 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 10 rentals that welcome pets

Vacation rentals with a pool
20 properties feature pools

Rentals with dedicated workspaces
30 properties have a dedicated workspace

Wi-Fi availability
50 of Santee vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Santee rentals

4.9 Average rating
Santee stays are highly rated by guests—averaging 4.9 out of 5!
Top-rated house rentals in Santee
Guests agree: these houses are highly rated for location, cleanliness, and more.

Fletcher Hills luxury, Sunset View, 4 BR, Pool/Spa
✨ Luxury Hillside Retreat | Private Entrance | Saltwater Pool & Spa Enjoy this luxuriously furnished 4-bedroom, 2-bath home in Fletcher Hills, CA, perched on a hill with stunning mountain and San Diego city views. Relax in your private saltwater pool and jacuzzi with color-changing LED lights, or unwind indoors with full kitchen access, high-speed Wi-Fi, and smart TVs with Netflix. Perfect for couples, business travelers, and families, this cozy yet elegant retreat makes you feel right at home.

San Diego Casita for 6 Morey de Prieto Surf Ranch
The Morey de Prieto Surf Ranch is truly awesome! Reserve your stay in this 2 Bed/1 Bath 650 sq. ft. casita for six. Home includes a kitchen with a GE electric cooktop, refrigerator, microwave/air fryer, rice cooker, mixer for drinks, sink with prep trays, Moen faucet fixtures, gorgeous shower, Krups coffee maker, 50" smart TV equipped with WiFi and NetFlix, mountain views, workspace and a sofa bed. Relax on the large 240 sq. ft. private deck featuring a fire pit, adirondack chairs and BBQ.

The Glass House - A Nature Retreat
Enjoy a unique retreat; 180 degrees of views from inside the home. Nestled at the end of a private road, our place is nearby great hiking and countryside wineries. The Glass House provides a magical space and nature retreat where individuals, couples, families and friends can gather together to re-connect with nature, each other, and themselves. The breathtaking mountain top views, the huge deck, hot tub, fireplace, and the open concept living space is unbeatable for the perfect getaway.

Classic Mid-Century Mount Helix Home with Views
Located in the exclusive Mount Helix neighborhood of La Mesa, this property is conveniently located near the 8 and 94 freeways for easy access to explore the greater San Diego area. Attractions like the historic Balboa Park with the San Diego Zoo or Sea World are a 15-25 minute drive away. With spacious interior and exterior spaces at the property, though, you may not want to leave. The property includes 4 bedrooms and 2.5 bathrooms with furnished living room, family room and kitchen.

Mid-Century Style Family House with Spa
This home is the epitome of 1950’s luxury. A perfect family oasis, you won’t even want to leave the property. Beautiful Mt. Helix mid-century modern family home with incredible views, designed by architect of original Las Vegas Desert Inn situated on nearly an acre. Less than 20 minute drive to beaches/Zoo/Sea World/Downtown. With a swimming pool, jacuzzi, and AC. Surrounded by orange, lemon, pomegranate trees and herb garden. No loud parties please, this is a quiet community.

Spacious home with incredible backyard views
This beautifully appointed home is located in a quiet neighborhood & is central to all San Diego attractions - 5 min to hiking, 15 min to beaches/Zoo/Sea World, 20 min to downtown & 35 min to Legoland. But should you chose to stay in to relax there's plenty to enjoy - Bocce Ball, hot tub, BBQ & gas fire pit. Perfect for families or small groups looking to enjoy San Diego. Please note, if you’re looking to have a party or gathering this is NOT the property for you.

Palm Cottage, San Diego
Palm Cottage sits in the heart of La Mesa Village, San Diego. Enjoy the charm of a historic home with a fully remodeled and stylish interior featuring both Dutch & French doors letting in plenty of sunshine. A large private yard w/ covered outdoor living area creates the ultimate indoor/outdoor lifestyle. You're steps from the local grocery store, village shopping, coffee shops, restaurants, bars and the trolley. You could not ask for a better location!

Quiet Country Home
Extremely clean home. Fenced private yard with BBQ & Tables. Outdoor smoking. 25 minutes to beach or downtown. Rural area with animals “talking”. Horses and carrots included. Seasonal Fruits & Vegetables. 1st bedroom: king/full bath. 2nd bedroom: queen/work desk. 3rd bedroom: full & 2 twin trundle. All dishes/appliances. Crib & Highchair available Host lives in a separate complete 1 bedroom studio with a shared laundry room.

QUIET HOME -3 Bedroom & Den, + POOL, sleep 8 plus
Welcome to the La Mesa Pool House! Our cozy house in La Mesa is the perfect place to relax and recharge with the family. This house is walking distance to many great La Mesa eateries such as Terra Restaurant and Surf and Soul. We are also located just 10 minutes away from San Diego State University and we are less than 20 minutes from all major attractions in San Diego: downtown, Little Italy, Zoo, Sea World, beaches and more!

SDSU Beach Cottage
Welcome to our charming SDSU Beach Cottage! Centrally located in a desirable San Diego neighborhood, you're just 10 minutes from many of the city's top attractions. Steps away, you'll find popular local dining, a wine bar, pub, natural market, pizza shop, nail salon, liquor store, and Einstein Bros. Bagels. Enjoy San Diego's best or unwind in our tropical backyard featuring outdoor games and ping pong. Minimum age to book: 25.

Beautiful 3,000 Sq Ft Tropical Oasis
Beautiful 4 Bedroom, 2 1/2 Bath Family Home Located in Tranquil Fletcher Hills. This 3,000 sq. ft. Home is Perfect for large families who wish to Relax in a Peaceful Setting. 24-hour self check-in keypad after 4pm and check-out at 11AM. Host does not allow parties/events. This is NOT a Party House! This home is located in a quiet residential neighborhood, Guests who do not respect this will be asked to leave.

Spacious & Fun | 5br, 4.5ba | Hot Tub | Views
Experience sunny San Diego from this 5 bedroom, 4.5 bathroom foothill home. Wake up to panoramic views of the surrounding hillsides and gather in the spacious living and dining rooms. The home is conveniently located just 15-20 minutes from San Diego's famous beaches and top attractions. After a day of exploration, unwind in the backyard area featuring a hot tub, fire pit, pool table, and life-sized chessboard.
Popular amenities for Santee house rentals
House rentals with a pool

The Queen House

The Agave House | Mountain Views & Pool

Entertainers Dream Pool Home

San Diego Pool | Fire Pit | Sunshine | Sleeps 10

Jamul Hacienda | Couples Retreat | Pool & Views!

Bright and spacious home with views, pool & spa.

ModernCoastal I View I Pool ITub

Modern Hilltop Home: Roomy, Views, Family-Friendly
Weekly house rentals

Luxury Retreat w/ Panoramic Views & Private Yard

Cozy 4bd Family Home near all SD Attractions!

3BR Standalone Home w/ Private Yard (Monthly+)

Villa Del Sole

Home In Santee

5 Bed Zen Oasis | Fire Pit, BBQ, Laundry, Parking

Spacious 5BR Group Retreat w/ Backyard Lounge

Cottage in the Garden! New! Modern!
Private house rentals

Family Oasis w/ Mountain Views & Playset

Lime Light La Mesa New 4BR 3BA, Group Friendly

San Diego Oasis | Pool Spa & Mountain Views

Modern Peaceful Retreat| 4 BR| Soaking Tub

Panoramic Ocean View Retreat - Family Friendly

Serene Lakeside Getaway-Sleeps 8

Luxe Retreat•Pool•Spa•Game Room•Home Theater•Yoga

San Diego Oasis- A Retro Retreat w/ King Size Bed!
When is the best time to visit Santee?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$31,818 GYD | G$30,772 GYD | G$37,679 GYD | G$31,818 GYD | G$33,493 GYD | G$26,794 GYD | G$45,843 GYD | G$40,191 GYD | G$36,423 GYD | G$36,423 GYD | G$39,982 GYD | G$33,074 GYD |
| Avg. temp | 15°C | 15°C | 16°C | 17°C | 18°C | 20°C | 21°C | 22°C | 22°C | 20°C | 17°C | 14°C |
Destinations to explore
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- Rentals with a hot tub Santee
- Lakehouse rentals Santee
- Rentals with a fire pit Santee
- Rentals with pools Santee
- Rentals with a patio Santee
- Family-friendly rentals Santee
- Pet-friendly rentals Santee
- Rentals with a washer and dryer Santee
- Rentals with a fireplace Santee
- Rentals with outdoor seating Santee
- House rentals San Diego County
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- Rosarito Beach
- SeaWorld San Diego
- Coronado Beach
- University of California-San Diego
- LEGOLAND California
- San Diego Zoo
- San Diego Zoo Safari Park
- Petco Park
- San Diego Convention Center E Ent
- Pacific Beach
- Balboa Park
- Tijuana Beach
- Pechanga Resort Casino
- San Diego State University
- Torrey Pines State Beach
- Anza-Borrego Desert State Park
- Oceanside City Beach
- Mission Beach
- Ocean Front Walk
- Las Olas Resort & Spa
- Moonlight State Beach
- Belmont Park
- Sesame Place San Diego
- Liberty Station





