
House vacation rentals in Santee
Find and book unique houses on Airbnb
Top-rated house rentals in Santee
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Santee house rentals
House rentals with a pool

La Jolla Beach House-Family Focused-3min to Beach

The Queen House

Sunny SD l Pool l BBQ l Pool Loungers l Sleeps 10

Mountain Top Getaway w/ Pool & Hot tub

Lionhead - Private Boutique Home

Bright and spacious home with views, pool & spa.

Custom Guesthouse, Balboa Park/Zoo/Hillcrest& pool

Updated TownHome, Great Location, Fantastic Views
Weekly house rentals

Discover La Mesa: Your Perfect Cozy Base

Farmhouse on Sunny Outdoor Dining area 20min to SD

Jamul Hacienda | Couples Retreat | Pool & Views!

Serene Sunny Loft | Beaches | Lakes | Trails

Contemporary Luxury Retreat

Entire house, fenced yard, and driveway

Studio In Home with Private Entry

Private House in the Hills, Pool, Pickleball court
Private house rentals

Whole home with Views, Spa & Movie RM | Sleeps 12

Escape to tranquility: the perfect retreat

Cozy, cute home: Welcome to Hilltop Sanctuary

Modern, Private, & Stylish Home

ModernCoastal I View I Pool ITub

Picturesque Spanish Casa on Ramona Hilltop

Sunny & Spacious 3BR Retreat w/ Parking & A/C

Entire 2-BR adorable home with free parking!
Quick stats about house rentals in Santee
Total rentals
50 properties
Total number of reviews
1K reviews
Family-friendly rentals
30 properties are a good fit for families
Pet-friendly rentals
10 properties allow pets
Rentals with a pool
10 properties have a pool
Rentals with dedicated workspaces
20 properties have a dedicated workspace
Destinations to explore
- Southern California Vacation rentals
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- Rentals with outdoor seating Santee
- Rentals with pools Santee
- Rentals with a patio Santee
- Rentals with a hot tub Santee
- Pet-friendly rentals Santee
- Rentals with a fireplace Santee
- Family-friendly rentals Santee
- Rentals with a fire pit Santee
- Lakehouse rentals Santee
- Rentals with a washer and dryer Santee
- House rentals San Diego County
- House rentals California
- House rentals United States
- Rosarito Beach
- Oceanside City Beach
- Torrey Pines State Beach
- Pacific Beach
- Tijuana Beach
- SeaWorld San Diego
- Coronado Beach
- University of California San Diego
- LEGOLAND California
- San Diego Zoo Safari Park
- Balboa Park
- Oceanside Harbor
- Pechanga Resort Casino
- Coronado Shores Beach
- Black's Beach
- Belmont Park
- Moonlight Beach
- Sesame Place San Diego
- Liberty Station
- Law Street Beach
- Torrey Pines Golf Course
- Santa Monica Beach
- USS Midway Museum
- Mission Beach