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Vacation rentals in Santa María

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Top-rated vacation rentals in Santa María

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
Two dome structures are positioned on a terrace overlooking a lush green valley. A vibrant sunset casts warm colors across the sky, with scattered clouds creating depth. String lights are visible along the railing, enhancing the natural setting adorned with trees.
Dome in El Valle de Antón
4.88 out of 5 average rating, 106 reviews

5 min from Valle I Domo No. 7-Free coffee

🌄 Dome in El Valle – Nature, peace and incredible views • 🆕 New Dome, Queen-Size Bed, Wi-Fi • 🚿 Private en-suite bathroom • 🌬️ Cool mountain climate all year round • 🌿 Surrounded by vegetation • 🌄 Breathtaking views • 🐶 1 small pet • ❄️ Fridge, microwave, and coffee maker (no kitchen) • ☕ Welcome courtesy: Small amounts of coffee, sugar, and cream for use at the start of your stay. • 🚗 5 minutes before El Valle (the last two minutes are a gravel road; small cars can pass) • 🕒 3:00 pm | 🕛 12:00 noon

Top guest favorite
Home in Costa Esmeralda
4.98 out of 5 average rating, 212 reviews

Beach House-Amazing Pool & Jacuzzi - Pet Friendly

Majestic Sands! Come relax with the whole family at this piece of paradise.located in a private beach community in Costa Esmeralda, San Carlos. Few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.Uninterruptible power with Smart Home Energy Management Systems.

Guest favorite
A private pool is surrounded by a smooth concrete deck, with gentle steps leading into the water. The adjacent open-air area features large glass doors that highlight the indoor living space, while the softly lit evening sky adds a serene ambiance.
Home in El Higo
4.97 out of 5 average rating, 30 reviews

CasAna

Fantástico lugar con espacios abiertos, luz natural y aire puro, 2 habitaciones con baño interno, terraza para recibir el amanecer y el atardecer, piscina privada que hace sentir que vuelas, mientras puedes compartir con amigos y familiares en un área grupal proporcionada por un espacioso deck, disfrutar de tus asados en la terraza y cocina equipada con todo lo que necesitas Ubicada a 10 mtos de Playa La Ermita y 12 mtos de la entrada del Valle, y a un salto del Restaurante Los Camisones.

Top guest favorite
Home in Rio Hato
4.98 out of 5 average rating, 137 reviews

Spacious House | Garden and Terrace | Pet Friendly

Discover the pleasure of staying in a private, elegant, and light-filled villa within the exclusive Playa Blanca Beach & Lagoon. Start your day with the tropical breeze on the terrace, relax by the pool, and enjoy a short 10-minute walk to the beach. Perfect for families and travelers seeking rest, security, and resort-style comfort. Ideally located 10 minutes from Scarlett Martínez Airport and 2 hours from Panama City, it's the perfect place for an unforgettable getaway by the sea.

Superhost
A scenic view of rolling hills under a colorful sky at sunset. Shades of orange, pink, and purple blend, creating a vibrant horizon. Lush trees are scattered across the landscape, adding a touch of greenery to the terrain.
Cottage in Olá
4.79 out of 5 average rating, 29 reviews

Country House in Olá, rivers, waterfalls, Los Picachos

Finca La Terapia lives up to its name, it is located among the mountains of the picturesque village of Olá de Penonomé, where you can disconnect from the busy day to day of the city. It has 42 private hectares to explore nature. The Olá district is characterized by having the most beautiful natural landscapes, among which we can mention Los Chorros de Olá, Chorros las Mesitas, Cerros los Picachos, Rio San Antonio, Balneario Brujas, among others, just a few minutes from the property.

Top guest favorite
Home in San Carlos
4.94 out of 5 average rating, 149 reviews

OceanView-Rooftop Jacuzzi&Pool | Concierge Service

Unique 3-story beach house – one of a kind. 7 bedrooms, 13 beds, 8.5 baths. hot water. Every room with full bath -AC’s and ceiling fans in all rooms, separate laundry -Rooftop area pool, Jacuzzi, bar, BBQ(charcoal & gas) with amazing ocean view -High ceilings, large open kitchen and living area. -Spacious balcony for dining or relaxing. - 5 min. walk to the beach. -Parking for up to 7 cars - Base rate covers up to 4 guests, with a $40 charge per additional person, per night.

Top guest favorite
An outdoor terrace is furnished with a sectional sofa in neutral tones and a low coffee table. A potted plant with green leaves and colorful flowers adds a vibrant touch. Large glass doors provide a view into the interior space, inviting natural light.
Villa in Lagartero
5 out of 5 average rating, 73 reviews

Private Villa & Pool, in Lago Bay, Santa Catalina

A beautiful stand-alone 60 sq mt villa, 1 King bed and 1 queen. King size bed in the master bedroom with black out drapes, Queen size bed and fold out couch in the loft area. Full kitchen, living and dining area, flat screen TV, Bathroom with soaps/shampoos, and rainfall showerhead. Large terrace with views as far as the eye can see, with BBQ, dining table and outdoor sectional sofa. Private swimming pool with seating area, pool lounge chairs, lighted gazebo and sun umbrellas.

Top guest favorite
A private pool is visible in the foreground, surrounded by a covered seating area with arranged outdoor furniture. Lush greenery is seen in the background, contributing to a serene environment. A gas grill and additional seating are positioned nearby under the protective roof.
Home in San Carlos
4.91 out of 5 average rating, 163 reviews

El Palmar, beach 50 meters away

Listen to the waves from the privacy of our terrace and create unforgettable memories in this unique and family-friendly accommodation just steps from the beach with a private pool. El Palmar is a quiet community with several restaurants available a few steps from the house. The property is fully fenced for the tranquility and safety of children and their pets. In addition, you have wifi, cable TV in both rooms and air conditioning in the dining room and in all the bedrooms

Guest favorite
A bright bedroom is displayed, featuring a spacious bed covered with a textured white blanket. A television is mounted on the wall opposite the bed. Natural light floods through large windows, accompanied by sheer curtains. A cozy orange chair and potted plant add a touch of warmth.
Tiny home in Playa El Jobo
4.93 out of 5 average rating, 45 reviews

Private Beach Studio · Sunset & Nature Views

Designed for comfort, functionality, and a welcoming atmosphere: • Comfortable bed for a truly restful sleep • Air conditioning • Wi-Fi • Kitchen • 2 Bathrooms • Parking Perfect for short stays or longer breaks. Wake up at your leisure, enjoy a relaxing coffee, stroll to the beach, or simply unwind in this space. This place is ideal for: • Romantic getaways • Personal retreats • “Work from the beach” • Escaping the hustle and bustle of the city

Top guest favorite
Condo in Rio Hato
4.98 out of 5 average rating, 156 reviews

Cozy Lagoon View Apartment | BBQ

Un espacio amplio y tranquilo en buenaventura con capacidad para (10) personas, donde podrán disfrutar de una barbacoa en su amplia terraza y su hermosa vista al Lago. Con 190m este hermoso apartamento cuenta con: - 3 + 1 dormitorios. - 3 baños completos. - Cocina completa. - Sala. - Comedor. - Terraza con parilla para barcacoa, abanico, sillas y sillones exteriores. - Área de Lavandería. - Dos (2) Estacionamientos. - Área para bicicletas o motos.

Guest favorite
A private pool reflects the clear sky, with a view of the ocean in the distance. Lush greenery and colorful vegetation surround the pool area, providing a serene setting. The pool deck features a tiled surface, enhancing the outdoor experience.
Cottage in El Palmar
4.9 out of 5 average rating, 109 reviews

El Palmar Beach House - spectacular ocean view!

You will love my space because of the spectacular view of the ocean, mountains and all of its surroundings. The beach is only 100 meters or 5 minutes walking; 150 meters from the Pan-American Highway; only 10 kilometers from the supermarkets, shops and restaurants of Coronado; and 30-45 minutes from El Valle de Antón. It comes equipped with everything you need to spend a few relaxing days and enjoy the beach. Maximum capacity: 8 people.

Guest favorite
Farm stay in Santa Fe
4.9 out of 5 average rating, 323 reviews

Sun Cabin at Finca Namuiki by the River

Spectacular contemporary style villa surrounded by local flowers and woods. The villas design enhances the relationship with the outside environment with panoramic windows which are found in the dining room and kitchen, this offers an awesome view of the mountains and green flora. The villa is located in a organic quiet farm, with abundant vegetation and great presence of birds.

Popular amenities for Santa María vacation rentals

  1. Airbnb
  2. Panama
  3. Herrera
  4. Santa María