House vacation rentals in Santa Fe

Find and book unique houses on Airbnb

Top-rated house rentals in Santa Fe

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Guest favorite
A charming cottage is showcased with a vibrant teal exterior. Sturdy steps lead to a welcoming porch, which overlooks a fenced pool area surrounded by green grass and trees. Sunlight bathes the property, enhancing its inviting appearance.
Home in San Leon
4.94 out of 5 average rating, 370 reviews

Lakeview Cottage (pool, fishing pier, lake)

Perfect for a small family vacation. This 3 bedroom cottage is larger inside than it may appear. The pool, the fishing pier on the lake, and the beautiful views are its best amenities. The porch is the ideal place to just relax and unwind while you take in the gorgeous view of the lake. The pool area is only a few steps from the porch. The living room offers plenty of space with comfortable furniture. Full kitchen with all appliances. Sleeps about 6. Pull out bed in livingroom. Pets ok limit 2

Guest favorite
The exterior of a single-story house is shown, featuring a light-colored facade and a well-maintained lawn. Steps lead to the front porch, adorned by bushes and landscaping elements. Large windows are visible on the sides, allowing natural light into the interior.
Home in Hitchcock
4.85 out of 5 average rating, 146 reviews

Cute and Spacious Modern Home for Large Groups

Bring the whole family to this family friendly home! Huge open rooms with lots of space for fun. At just 20 minutes from Galveston, this is a great pet-friendly home for trips to the beach and for so many of the activities nearby. Check out the huge living room, large kitchen, and super clean atmosphere. We have 3 great bedrooms, and two bathrooms for large groups. Fire pit with seating , large front and back porch, plenty of space inside and out for activities. Plenty of covered parking

Guest favorite
Home in League City
4.95 out of 5 average rating, 104 reviews

Entire Home in League City near NASA & Kemah

This hidden gem is located in the heart of League City. Serene and peaceful are a couple of ways to describe this charmer. Nestled beneath live oak and pecan trees, this home offers a spacious backyard, patio, and kayaks for guests to enjoy. Take a 2 minute stroll to Heritage Park which boasts a lovely kayak launch ramp and watch a sunset views over Clear Creek. Spend the day at nearby NASA or the Kemah Boardwalk. Not to mention, Downtown Houston and Galveston are just a short drive away.

Guest favorite
A well-maintained single-story home is showcased, featuring a brick facade and a spacious garage. A paved driveway leads to the entrance, with manicured grass and a clear blue sky providing a bright backdrop. Windows allow ample natural light to enhance the home's exterior.
Home in Texas City
4.84 out of 5 average rating, 135 reviews

Modern Comforts Cruisers Landing

Our cozy retreat offers luxurious amenities: a soaker tub, Brand new A/C, high-speed WiFi, a 70-inch Roku TV, a chef's dream kitchen and an office set off on its own. The home is perfectly situated, a short drive from I-45 so you can quickly and easily travel North to Houston or South to Galveston. The neighborhood offers parks, ponds, walking trails and a dog park. This is the perfect spot for cruisers departing from Galveston or travelers wanting to experience the Greater Houston area.

Guest favorite
A serene view of the bayou reflects soft pastel colors of the sky at sunset. Lush greenery lines the banks, with trees providing shade on either side. The calm waters create a mirror-like surface, enhancing the tranquil ambiance of the country setting.
Home in La Marque
4.87 out of 5 average rating, 137 reviews

Livin’ the Highland Life

"The waterfront house is just like it sounds. You can't get any closer to Livin' the high life. Located in a quiet country community, away from the hustle and bustle of the city, but still close enough to enjoy the great amenities that Galveston has to offer. Enjoy the country setting with unobstructed views from the kitchen, living room, master bedroom or the patio overlooking the Bayou. Stay a while - there's a desk for working, fish off the pier, or relax under the great oak tree.

Top guest favorite
A spacious living area features a stone fireplace as a focal point, accompanied by a flat-screen TV above it. A piano stands to the left, while natural light streams through large windows. Comfortable seating is provided by a leather sofa and two armchairs, complemented by a wooden coffee table.
Home in Pearland
4.99 out of 5 average rating, 114 reviews

Pristine Retreat for Family & Friends

🍐Your East Pearland comfort stay to visit families & friends, spend summer breaks and holidays, weddings & local or religious events. Stay for business, medical reasons, or temporary housing while relocating/renovating. **2000-sqft home ideal for midterm stays!** ~25 mins to Hobby Airport & Downtown ~25 mins to Museums, Med Center, NRG Stadium, Zoo, Bellaire ~30 mins to NASA, Kemah ~40 mins to Galveston & Moody Gardens Short drive to Friendswood, Clear Lake, Manvel/Alvin, Pasadena!

Superhost
The front porch is framed by green grass and decorative shrubs. A seating area with comfortable chairs is positioned under the covered section. A wooden swing set is visible in the yard, contributing to the family-friendly environment.
Home in Dickinson
4.88 out of 5 average rating, 154 reviews

Cheerful 3 bedroom home with loft

Make some memories at this unique and family-friendly place. 2 bedrooms and 2 bathrooms downstairs with a loft upstairs hosting two beds. Great for multiple families, or families with children. This updated home is cozy and bright. Great for business professionals or friends and family trying to get away. Just minutes from NASA Johnson Space Center, Clear Lake, one of the biggest yachting communities in the USA, and Galveston Island. Your home away from home awaits!

Guest favorite
Home in League City
4.88 out of 5 average rating, 102 reviews

Comfortable Spacious 4 Bedroom Quiet Retreat

Our Airbnb home is in a quiet, safe, tranquil residential neighborhood, it’s perfect for short term and longer term rental needs. Great for those travelers looking for space and convenience. You can expect a peaceful and secure environment throughout your stay and it is always cleaned and sanitized in between guests, there are nearby shopping, restaurants, entertainment, easy access to I-45 in League City to Webster, Galveston, Houston surrounding areas.

Guest favorite
A cozy living area features a light-colored sofa adorned with orange and patterned cushions. A wooden coffee table sits at its center, accompanied by two dark blue stools. A wall-mounted art piece displays a serene landscape, while natural light illuminates the room from a nearby window.
Home in Galveston
4.95 out of 5 average rating, 168 reviews

Paradise Palms, 1 min to Moody Gardens

Come stay with us at our modern and upscale Airbnb. Every aspect of our place has been furnished only with the finest quality that we would stay in ourselves. -Upstairs unit only 1 queen bed The location is in an upscale neighborhood that is only a 3min drive or a 10min walk to the beach. Also a 5min drive to many popular local restaurants on 61st. As well as a 1min drive to Moody Gardens and Schliterbahn! *Downstairs is a separate Airbnb unit*

Guest favorite
A serene outdoor area features a large swimming pool accompanied by a relaxing jacuzzi. Lush palm trees surround the space, providing a tropical ambiance. The fenced backyard adds privacy, enhancing the enjoyment of this inviting poolside setting.
Home in League City
4.91 out of 5 average rating, 225 reviews

Beach Themed Oasis with Jacuzzi/Pool

Bring the whole family along to this spacious home to enjoy all to yourselves. Swim in the massive pool or lay in the jacuzzi by the 2 pergolas. Cook BBQ outside on the grill (no backyard neighbors). 1 King size master bedroom, 1 full size bedroom and 1 full size kids bedroom, convertible sofa and air mattress provided upon request. Gorgeous kitchen area and massive family room with blazing fast cable/ internet and streaming services.

Guest favorite
The exterior of a remodeled home is displayed, featuring a combination of brick and siding. Large windows allow natural light to enter, and a driveway leads to an attached garage. Surrounding trees provide shade and a serene atmosphere.
Home in Dickinson
4.86 out of 5 average rating, 106 reviews

Spacious 3BR/2BA: Near NASA, Kemah, Galveston

Welcome to our peaceful and comfortable home, perfect for families, friends, or business travelers. Enjoy a spacious living area, fully equipped kitchen, and relaxing bedrooms for a restful stay. Located 5 minutes from I-45, with quick access to Downtown Houston, NASA, Kemah Boardwalk, Galveston, Moody Gardens, and nearby beaches. Baybrook Mall, restaurants, shopping, H-E-B, and Kroger are all just minutes away.

Top guest favorite
The kitchen features a contemporary design with white cabinets, a gray granite countertop, and a mosaic tile backsplash. A dining area is visible, complemented by large windows that provide natural light. A comfortable living space includes a dark sofa, decorative pillows, and a coffee table.
Home in Kemah
4.96 out of 5 average rating, 206 reviews

Stylish home heart of NASA, Boardwalk, Clear Lake

Relax with the whole family at this recently remodeled 960 sq ft home that sits in a serine and quiet neighborhood in Kemah, TX. The property is 2 blocks from Clear Lake with access to a private park, a fishing pier and boat ramp. We are centrally located between the Kemah Boardwalk, NASA Space Center, yachting centers, and surrounded by shopping and dining venues.

Popular amenities for Santa Fe house rentals