
Apartment vacation rentals in Santa Fe
Find and book unique apartments on Airbnb
Quick stats about apartment rentals in Santa Fe

Total vacation rentals
Explore 390 vacation rentals in Santa Fe

Verified guest reviews
Over 6,360 verified reviews to help you choose

Family-friendly vacation rentals
80 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 90 rentals that welcome pets

Vacation rentals with a pool
70 properties feature pools

Rentals with dedicated workspaces
130 properties have a dedicated workspace

Wi-Fi availability
390 of Santa Fe vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Santa Fe rentals

4.8 Average rating
Santa Fe stays are highly rated by guests—averaging 4.8 out of 5!
Top-rated apartment rentals in Santa Fe
Guests agree: these apartments are highly rated for location, cleanliness, and more.

Large 2 rooms without balcony Galvez w/ pool - Garage opt
Enjoy this beautiful and bright apartment, located on the iconic Boulevard Gálvez, one of the most beautiful and safest areas of Santa Fe. Steps from the suspension bridge and the waterfront. Ideal for enjoying Santa Fe during the day and night, with bars and restaurants in a large setting of vegetation. Located on the 5th floor with a beautiful view that reaches the Paraná River. The building has 24-hour security, three elevators, a full SUM for events, and a free pool to enjoy.

Excellent location, boulevard area, bars, downtown
Located in the heart of the city, this comfortable apartment is in one of the most sought-after areas of the city, surrounded by bars, restaurants and within walking distance of the main boulevard. Ideal for those who enjoy urban life, with everything within reach, shops, public transport and green spaces. The apartment is functional and offers a modern and cozy atmosphere, perfect for both temporary stays and for those looking for comfort and an excellent location.

Equipped and comfortable apartment in Santa Fe
Modern, bright, and fully furnished and equipped, this beautiful 12th-floor apartment offers an excellent view and everything you need for a comfortable and pleasant stay. Its location is unbeatable: just steps from the shopping area, historic center, the port, and right on the corner of the School of Economics - Universidad Nacional del Litoral. Perfect for business trips, study stays, or tourism. We look forward to welcoming you for a great stay in Santa Fe!

Apartment with garage in downtown area
Enjoy Santa Fe in this accommodation equipped for a comfortable stay. Prime location, very close to Alem Avenue, main access to the city, in the heart of the shopping center, close to the private sanatorium area, 100 meters from the pedestrian area with commercial and gastronomic offers, 250 meters from the bus terminal and 5 minutes from the bar and restaurant area. With a garage in the same building, it offers beautiful views at all times of the day.

Apartment in Santa Fe, Capital
✨ A unique place with its own style in Santa Fe ✨ 📍 Located in an iconic building with a Messi mural 🛏️ 1 bedroom | 🛁 Full bathroom | 🚗 Garage included Enjoy a unique stay with all the comforts: ✔ Equipped kitchen ✔ Air conditioning and heating ✔ Large balcony ✔ WiFi + Smart TV ✔ Pool with 360° view of the river 🌅 ✔ 24-hour security Steps to the Pedestrian Street, Shopping, Casino, Puerto Plaza and Bus Terminal 🚫 Parties are not allowed –

Apartment in Puerto Amarras
The apartment is located in the port of Santa Fe, with 24-hour security. It is located in a strategic place near downtown, 1 km from the bus terminal, near hospitals, sanatoriums, shopping malls, casino. The apartment has two S-Mart TVs, two cold/hot air conditioners, a sofa bed, blackout curtains, a double bed, all the dishes, a four-burner stove, a built-in oven, a washing machine, a coffee maker, an iron, and linen Absolutely nothing is missing

Santa Fe Central Department
Beautiful apartment in the heart of Santa Fe. Enjoy a comfortable and modern stay in this cozy apartment located in the heart of Santa Fe. Accommodates up to 4 people, ideal for couples, families or travelers. The apartment has a balcony overlooking the harbor, in addition to being in front of the famous Messi mural. 100 meters from the bus terminal. 300 meters from downtown and casino. Close to all the city's health centers.

Penthouse with an incredible terrace and garage
Relax in this quiet and elegant space in this magnificent penthouse, with an incredible view of the entire city, with an excellent location. It's a large studio with the best views in the city. Keep in mind that the apartment is located on the building's terrace, so you take the elevator up to the 22nd floor and then climb one floor by stairs, as shown in the photos. Not recommended for people with difficulty climbing stairs.

Premium 2-bedroom apartment in the best location.
Large two-bedroom, two-bathroom apartment in a first-class building on the most exclusive avenue in the city of Santa Fe. The kitchen is in a separate environment. Balcony with panoramic views of the Setubal lagoon. The building has a large infinity pool and a spacious dry solarium. The location is full of local shops, bars, cafes, and restaurants. Garage availability can be checked, with an additional charge.

Centrally located apartment, Santa Fe
Enjoy its good location in the heart of Santa Fe city. This centrally located accommodation gives you easy access to the main points of interest, is close to the port, a few meters from the shopping center, less than 300 meters from the bus terminal, close to major urban bus stops. Enjoy comfort and tranquility in our cozy and well-equipped space. If you have any concerns, your inquiry will be welcome!

Dreamy studio apartment, river view, total relaxation
Welcome to your dream getaway overlooking the river! This exquisitely designed studio offers a unique experience of comfort and elegance. Enjoy picturesque sunrises from your panoramic window and immerse yourself in the serenity of the river flowing right outside your door. Equipped with modern amenities and luxurious details, this intimate space is perfect for a romantic getaway or a quiet retreat.

Quiet retreat in the heart of Santa Fe
Located in the downtown area of Santa Fe, with easy access by public transportation. Just a few blocks from plazas, Boulevard Gálvez, the shopping district and the bus terminal, surrounded by shops and services. Set in the middle of the block, the apartment offers a quiet atmosphere in the heart of the city, with essential amenities and modern equipment, ideal for both rest and work.
Popular amenities for Santa Fe apartment rentals
Weekly apartment rentals

Panoramic point, 22nd floor with garage included

Apartment Centrally located, unobstructed view, and garage

Centrally located apartment with 2 bedrooms and parking (cost not included)

Unmissable apartment. Prime location

Maruca's penthouse

A few meters from Boulevard and U.N.L.

Warm- Downtown with a view and sun

Modern apartment. Find your place in Santa Fe
Private apartment rentals

A central, spacious and comfortable apartment.

Apartment with Garage and Private Terrace

Centrally located and spacious apartment

Studio apartment 15 meters from Santa Fe's pedestrian street.

Sancor Department

Apartment in Microcentro, Santa Fe. Balcony + Wi-Fi + A/C

New Downtown Free Garage Pool

Port of Santa Fe
Family-friendly apartment rentals

Boulevard premium chic

Monoambiente zona Parque Federal (10 min Terminal)

Apartment Plaza A

Apartment in Santa Fe

An apartment in an excellent location

Warm and spacious apartment in the heart of downtown

Centrally located apartment in the MIT clinics area

Boutique apartment.
When is the best time to visit Santa Fe?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$8,994 GYD | G$9,204 GYD | G$9,413 GYD | G$8,785 GYD | G$9,204 GYD | G$9,204 GYD | G$8,994 GYD | G$9,204 GYD | G$8,785 GYD | G$8,994 GYD | G$8,785 GYD | G$8,994 GYD |
| Avg. temp | 26°C | 25°C | 23°C | 19°C | 16°C | 13°C | 12°C | 14°C | 17°C | 20°C | 22°C | 24°C |
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