
Apartment vacation rentals in Santa Fe
Find and book unique apartments on Airbnb
Quick stats about apartment rentals in Santa Fe

Total vacation rentals
Explore 390 vacation rentals in Santa Fe

Verified guest reviews
Over 6,360 verified reviews to help you choose

Family-friendly vacation rentals
80 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 90 rentals that welcome pets

Vacation rentals with a pool
70 properties feature pools

Rentals with dedicated workspaces
130 properties have a dedicated workspace

Wi-Fi availability
390 of Santa Fe vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Santa Fe rentals

4.8 Average rating
Santa Fe stays are highly rated by guests—averaging 4.8 out of 5!
Top-rated apartment rentals in Santa Fe
Guests agree: these apartments are highly rated for location, cleanliness, and more.

A central, spacious and comfortable apartment.
Located in the heart of Santa Fe, this spacious and comfortable apartment offers a practical and comfortable stay. Three blocks from the pedestrian area, main banking area and one block from the bus terminal. Close to clinics, sanatoriums, Puerto and La Ribera Shopping. Equipped with wifi, 43" Smart TV, hot/cold air conditioning in the living room and bedroom, refrigerator and fully equipped kitchen. Ideal for business trips, medical consultations or just spending a few days in Santa Fe.
FamilyLocationSleep quality

Premium riverfront apartment with great view
Modern riverfront apartment, designed to provide comfort and a unique experience. It has large, bright spaces, an integrated living/dining room, a fully equipped kitchen, a comfortable bedroom, and a full bathroom. Its balcony offers a prime view that allows you to enjoy unforgettable sunrises and sunsets. Its location combines tranquility and proximity to the main points of interest, restaurants, and recreational spaces. It's an excellent option for both travel and relaxation.
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Equipped and comfortable apartment in Santa Fe
Modern, bright, and fully furnished and equipped, this beautiful 12th-floor apartment offers an excellent view and everything you need for a comfortable and pleasant stay. Its location is unbeatable: just steps from the shopping area, historic center, the port, and right on the corner of the School of Economics - Universidad Nacional del Litoral. Perfect for business trips, study stays, or tourism. We look forward to welcoming you for a great stay in Santa Fe!
LocationValueAccess

Apartment with garage in downtown area
Enjoy Santa Fe in this accommodation equipped for a comfortable stay. Prime location, very close to Alem Avenue, main access to the city, in the heart of the shopping center, close to the private sanatorium area, 100 meters from the pedestrian area with commercial and gastronomic offers, 250 meters from the bus terminal and 5 minutes from the bar and restaurant area. With a garage in the same building, it offers beautiful views at all times of the day.
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Apartment in Santa Fe, Capital
✨ A unique place with its own style in Santa Fe ✨ 📍 Located in an iconic building with a Messi mural 🛏️ 1 bedroom | 🛁 Full bathroom | 🚗 Garage included Enjoy a unique stay with all the comforts: ✔ Equipped kitchen ✔ Air conditioning and heating ✔ Large balcony ✔ WiFi + Smart TV ✔ Pool with 360° view of the river 🌅 ✔ 24-hour security Steps to the Pedestrian Street, Shopping, Casino, Puerto Plaza and Bus Terminal 🚫 Parties are not allowed –
LocationWalkabilityAccuracy

Apartment in Puerto Amarras
The apartment is located in the port of Santa Fe, with 24-hour security. It is located in a strategic place near downtown, 1 km from the bus terminal, near hospitals, sanatoriums, shopping malls, casino. The apartment has two S-Mart TVs, two cold/hot air conditioners, a sofa bed, blackout curtains, a double bed, all the dishes, a four-burner stove, a built-in oven, a washing machine, a coffee maker, an iron, and linen Absolutely nothing is missing
LocationValueQuiet

Beautiful 2 with s/Bv. Gálvez, w/pool -Cochera opc
This apartment located in the heart of Santa Fe city offers a unique lodging experience. Located in one of the best areas, steps away from squares, restaurants, shops and main attractions, this space is ideal for enjoying the city in an unbeatable way. Tasteful decoration, and very comfortable. It has 2 strategically located air conditioners and radiator heating in each room for winter. Definitely an excellent choice in Santa Fe.
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Santa Fe Central Department with Garage
Beautiful apartment in the heart of Santa Fe. Enjoy a comfortable and modern stay in this cozy apartment located in the heart of Santa Fe. Accommodates up to 4 people, ideal for couples, families or travelers. The apartment has a balcony overlooking the harbor, in addition to being in front of the famous Messi mural. 100 meters from the bus terminal. 300 meters from downtown and casino. Close to all the city's health centers.
ValueLocationIndoor spaces

Premium 2-bedroom apartment in the best location.
Large two-bedroom, two-bathroom apartment in a first-class building on the most exclusive avenue in the city of Santa Fe. The kitchen is in a separate environment. Balcony with panoramic views of the Setubal lagoon. The building has a large infinity pool and a spacious dry solarium. The location is full of local shops, bars, cafes, and restaurants. Garage availability can be checked, with an additional charge.
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Centrally located apartment, Santa Fe
Enjoy its good location in the heart of Santa Fe city. This centrally located accommodation gives you easy access to the main points of interest, is close to the port, a few meters from the shopping center, less than 300 meters from the bus terminal, close to major urban bus stops. Enjoy comfort and tranquility in our cozy and well-equipped space. If you have any concerns, your inquiry will be welcome!
LocationValueAccess

Dreamy studio apartment, river view, total relaxation
Welcome to your dream getaway overlooking the river! This exquisitely designed studio offers a unique experience of comfort and elegance. Enjoy picturesque sunrises from your panoramic window and immerse yourself in the serenity of the river flowing right outside your door. Equipped with modern amenities and luxurious details, this intimate space is perfect for a romantic getaway or a quiet retreat.
FamilyValueCondition

Quiet retreat in the heart of Santa Fe
Located in the downtown area of Santa Fe, with easy access by public transportation. Just a few blocks from plazas, Boulevard Gálvez, the shopping district and the bus terminal, surrounded by shops and services. Set in the middle of the block, the apartment offers a quiet atmosphere in the heart of the city, with essential amenities and modern equipment, ideal for both rest and work.
LocationIndoor spacesAmenities
Popular amenities for Santa Fe apartment rentals
Weekly apartment rentals

Unmissable apartment. Prime location
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Centrally located apartment in the MIT clinics area
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A few meters from Boulevard and U.N.L.
LocationHospitalityCondition

Apartment in Microcentro, Santa Fe. Balcony + Wi-Fi + A/C
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Monoambiente An excellent location
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Panoramic point, 22nd floor - Garage and Security
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Maruca's penthouse
LocationCheckoutIndoor spaces

An apartment in an excellent location
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Private apartment rentals

Entire apartment in Santa Fe Capital
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Centrally located apartment with 2 bedrooms and parking (cost not included)
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Your Warm Space in the City
LocationAmenitiesHospitality

Apartment in Recoleta
LocationFamilyCheck-in

Cozy apartment located in the heart of downtown
LocationParkingHospitality

Bright loft with barbecue 1/2 block from the Lighthouse
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Modern apartment. Find your place in Santa Fe
LocationCleanlinessAmenities

Warm- Downtown with a view and sun
LocationValueCleanliness
Family-friendly apartment rentals

Candioti neighborhood apartment
ValueLocationAccuracy

Apartment overlooking the lagoon on the waterfront
LocationAccuracyNearby

Centrally located and spacious apartment
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New Downtown Free Garage Pool
LocationGetting aroundBathroom

Exceptional luxury apartment with river view
LocationFamilyCleanliness

Bright apartment, 2 bedrooms, in an excellent area. With a garage!
LocationFamilySleep quality

Cozy and functional apartment in Santa Fe.
LocationComfortHospitality

Chacabuco and Güemes Apartment
ValueLocationHeating
When is the best time to visit Santa Fe?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$8,997 GYD | G$9,206 GYD | G$9,415 GYD | G$9,625 GYD | G$9,625 GYD | G$9,415 GYD | G$8,997 GYD | G$9,206 GYD | G$8,788 GYD | G$8,997 GYD | G$8,788 GYD | G$8,997 GYD |
| Avg. temp | 26°C | 25°C | 23°C | 19°C | 16°C | 13°C | 12°C | 14°C | 17°C | 20°C | 22°C | 24°C |
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