House vacation rentals in Santa Cruz County

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Top-rated house rentals in Santa Cruz County

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Guest favorite

A modern kitchen is equipped with stainless steel appliances, including a refrigerator and dishwasher. White cabinets provide ample storage, while a dining table for four sits beside a window, allowing natural light to pour in and offering views of the surrounding landscape.

Home in Elgin

4.97 out of 5 average rating, 118 reviews

Modern Elgin Home: Walk to Wineries + Pets Welcome

With its elegant design, secluded location, and 1-bedroom, 1-bath, ‘Starry Night Guest Retreat’ is the perfect cozy vacation rental! Start your days off by relaxing on the patio and admiring the views of the Mustang Mountains. When it’s time to explore, head to Deep Sky Winery for a glass of wine, try out some nearby birdwatching, or enjoy the farm animals grazing the meadow. Finish your stay with a visit to the old town of Tombstone and Kartchner Caverns State Park to see all that Elgin offers!

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Guest favorite

The exterior of a charming ranch house is depicted, featuring a warm adobe façade in soft pink tones. A clay tile roof complements the landscape, while lush greenery and desert plants frame the entrance. The driveway is lined with gravel, leading to the inviting porch area.

Home in Tubac

5.0 out of 5 average rating, 5 reviews

Valle Verde Ranch House

Nestled near the Santa Cruz River in Tubac, Arizona, this remarkable six-acre retreat offers a captivating blend of history and modern comfort. Dating back to 1938, the 4400 square foot ranch house boasts three bedrooms and three bathrooms, adorned with exquisite Southwestern décor. Experience an unforgettable stay with a formal dining room, a fully-equipped kitchen, and a fabulous great room featuring a pool table. Our four-acre private mesquite forest preserve abuttes the historic Anza Trail.

LocationFamilyHiking

Guest favorite

The exterior features a welcoming entrance with a combination of rustic and vibrant elements. Adirondack chairs in turquoise and red are positioned in a small patio area, and a flag is displayed prominently. Native landscaping complements the porch area, creating a friendly ambiance.

Home in Patagonia

4.84 out of 5 average rating, 148 reviews

Javelina Corner

Our place is close to Patagonia Lake, 10 minute drive, Patton's hummingbird center, 2 minute drive or 8 minute walk. There is access to the Arizona trail at two locations within 10-20 minute drive and numerous other hikes! Tombstone, Bisbee, The Art haven of Tubac is close by and Nogales Mexico is 19 miles. You’ll love our place because of the neighborhood, the coziness, and the comfy beds. Our place is good for couples, solo adventurers, business travelers, families , and furry friends (pets).

FamilyValueOutdoor spaces

Guest favorite

A well-maintained yard features mature trees providing shading, with a spacious lawn that stretches towards the hacienda. The structure's exterior is characterized by a traditional design, complemented by a covered porch area. Clouds drift in the sky, hinting at a serene atmosphere.

Home in Arivaca

4.86 out of 5 average rating, 119 reviews

Private Getaway: Pandora Ranch House in Arivaca

Pandora is a private remote hacienda located on 20 acres in the high grasslands of the Sonoran Desert with 6 bedrooms, 6 bathrooms, a fully equipped kitchen, a dining room, living room. A well maintained yard with mature trees and charcoal BBQ grills invites to enjoy time outside. Minutes away from the quaint town of Arivaca, Buenos Aires Wildlife Refuge, Arivaca Lake and the Coronado National Forest Pandora offers easy access to hiking, boating,fishing, bird watching and off road exploration.

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Superhost

The spacious ranch house is situated on a gravel driveway, surrounded by green grass and gently rolling hills. A clear blue sky with wispy clouds serves as a backdrop, highlighting the peaceful rural setting and bringing attention to the home's exterior features.

Home in Sonoita

4.94 out of 5 average rating, 103 reviews

McFitz Guest Ranch

McFitz Ranch House is fully remodeled and available. Its a 3000 sqft 4 bedroom 3 bathroom w/ two master suites, and game room on 5 acres of beautiful horse property. Close to many attractions such as several wineries, brewery, the Sonoita rodeo grounds, Parker Canyon and Patagonia Lake, La Cienega Preserve and more. This location is ideal for Wedding Parties, Wine vacations, Rodeo, Kentucky Derby Fans, bird watching the Santa Cruz County Fair, hunting seasons or family weekends to the lake

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Guest favorite

A southwestern-style ranch home is nestled on expansive land, surrounded by rolling plains. The structure features a white exterior with traditional architectural elements. Majestic mountains are visible in the distance under a clear sky, enhancing the serene rural landscape.

Home in Elgin

4.93 out of 5 average rating, 169 reviews

Peaceful SW-style ranch home in wine country

Welcome to our southwestern style ranch home in Sonoita/Elgin, Arizona wine country! Our home is 2,600 square feet and sits on 40 acres with unobstructed views of the beautiful Santa Rita Mountains. Our entire home is available for a wine country getaway. With three bedrooms, two full bathrooms with dual vanities, a half bath, an amazing kitchen, dining, two living spaces, and high-speed Internet, our home is ideal for two or three couples, or a family getaway (crib available for use).

LocationFamilyBackyard

Top guest favorite

A dining area features a long wooden table surrounded by six dark chairs. A large chandelier shaped like a star hangs above the table, casting intricate patterns on the walls. A decorative centerpiece of fresh fruits adds a touch of color.

Home in Tubac

5.0 out of 5 average rating, 142 reviews

Una Escapada en Tubac

Amazing luxury vacation rental in beautiful, historic Tubac, Arizona. Located in The Sanctuary neighborhood, this home is within walking distance of either The Village of Tubac or the Tubac Golf Resort. Plenty of nearby activities including hiking, golf, birdwatching, or day trips to southern Arizona. Visit unique shops in The Village of Tubac or the Resort for furnishings, jewelry, or great food at a variety of restaurants. Come see everything that southern Arizona has to offer!

ValueLocationWalkability

Top guest favorite

A Santa Fe style residence is framed by native desert vegetation, including cacti and broader plants. A winding pathway leads toward the whitewashed exterior, partially obscured by trees, enhancing the natural surroundings of the peaceful community.

Home in Tubac

5.0 out of 5 average rating, 22 reviews

Mesquite Haven

Fantastic home located in a peaceful and beautiful community surrounded by desert nature. This Santa Fe style residence invites you to relax and escape a busy lifestyle while still having access to modern amenities. Enjoy life outdoors in a basically traffic free private community rich with local flora and fauna. The location is great for morning or evening walks or runs, Tubac Resort wedding guests, visits to the village, hiking trips, etc.

LocationFamilySleep quality

Top guest favorite

A green casita is situated in an open landscape, surrounded by a rustic fence. A gravel driveway leads towards the entrance, with an American flag waving gently overhead. Lush grass and a few scattered trees enhance the rural setting under a clear blue sky.

Home in Sonoita

4.98 out of 5 average rating, 289 reviews

Sky Island Retreat Sonoita, AZ.

Sky Island Retreat is a quiet and peaceful hilltop retreat in which you can relax and enjoy the natural beauty of this historic area. The casita is the original but updated ranch house built in the late 60’s. We have kept much of its original charm while upgrading to modern comfort and conveniences. We are located on a privately gated property just minutes from the heart of Sonoita and Southern AZ’s growing wine country.

FamilyValueParking

Top guest favorite

A modern kitchen area features wooden cabinetry and stainless steel appliances, including a stove and refrigerator. Natural light fills the space through the window, and a cozy dining table is set nearby. Decorative elements, such as wall art, enhance the inviting design.

Home in Sonoita

4.99 out of 5 average rating, 358 reviews

Winemaker's Casita in the heart of Wine Country

The perfect casita for your wine tasting getaway! Our cozy space is full of local charm and minutes away from Elgin and Sonoita's many wineries. Centrally located near the Sonoita Crossroads, the Winemaker's Casita is walking distance from local restaurants, including Copper Brothel Brewery and Tia 'Nita's Cantina. Owned + operated by the proprietors of Rune Wines.

FamilyLocationWalkability

Top guest favorite

A clear blue pool is visible, reflecting sunlight under a vast sky adorned with fluffy white clouds. The surrounding landscape features rolling hills and mountains in the distance, highlighting the serene nature of the location.

Home in Patagonia

4.94 out of 5 average rating, 70 reviews

Poolside Escape Near Patagonia

Unwind at this scenic hilltop retreat just a mile south of Patagonia, AZ. Enjoy a private pool with stunning Red Mountain views, 3 spacious bedrooms, and a dedicated office space. Close to hiking, biking, and town. Relax in modern comfort, soak up breathtaking sunsets, and explore the best of Southern Arizona. Pet-friendly for making memories with the whole family!

FamilyLocationLong stay

Guest favorite

The exterior of the home is presented, featuring a modern single-story structure framed by desert landscaping. A gravel pathway leads to the entrance, while two trees provide a natural element. A colorful sky is visible, suggesting a vibrant sunset.

Home in Rio Rico

4.98 out of 5 average rating, 43 reviews

Large group getaway - 4 bed w/ updated appliances

Welcome to this new construction 4-bedroom, 2-bathroom home in Rio Rico! Perfect for families or groups. Enjoy an open-concept living space with a gourmet kitchen, granite countertops, and stainless steel appliances. Visit nearby attractions such as Tumacácori National Park, explore nearby Tubac & Nogales AZ, or enjoy family time by the fire pit!

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