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Guesthouse vacation rentals in Santa Ana

Find and book unique guesthouse rentals on Airbnb

Top-rated guesthouse rentals in Santa Ana

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Top guest favorite
A modern living area features a light-colored sofa and a wooden coffee table placed on a soft area rug. In the background, a dining table with chairs is visible, alongside a well-equipped kitchen with wooden cabinets. Natural light brightens the space through large windows.
Guesthouse in Santa Ana
4.97 out of 5 average rating, 170 reviews

Cozy 2-bedroom private guesthouse near South Coast

Step into this getaway house, away from all the hustle and bustle of daily life. You will find calmness and peace on your vacation. Indulge in a hot cup of coffee under the patio in a quiet environment or make your family a hot breakfast in the new kitchen before you head out to nearby attractions. Just bring your sun glasses and luggages. 5 minutes from South Coast Plaza. 25 Minutes from Disneyland Park. 20 minutes from all beautiful beaches, shopping centers and top restaurants of the region.

Top guest favorite
A comfortable living area features a light-colored sofa adorned with decorative pillows. A medium-sized television is positioned on a sleek wooden console. Large windows allow natural light to fill the space, offering views of surrounding greenery, while a wooden coffee table rests in front.
Guesthouse in Santa Ana
4.95 out of 5 average rating, 1,357 reviews

Quiet Peaceful Studio

Private studio apartment. Second-story unit, set back from the street, in a separate building behind the hosts' home. Located in a beautiful historic neighborhood, on a quiet street shaded by oak trees. Disneyland and the Anaheim Convention Center are only 10 minutes away. The Honda Center and Anaheim Stadium 5 minutes. The beaches are an easy 20 minute drive. Excellent restaurants and shopping are abundant. Close to Old Town Orange, Chapman University, and the Santa Artists Village.

Top guest favorite
A modern kitchen and living area are seen, featuring white cabinetry and stainless steel appliances. A wooden table with metal stools is positioned near the kitchen, while a blue couch with decorative cushions faces a light wood coffee table. Natural light enters through a window above the sink.
Guesthouse in Midway City
4.93 out of 5 average rating, 288 reviews

Oasis new unit near beaches, Little SG, Disney

This secluded unit is a newly built backyard cottage in the center of Orange County. 500 sqft. It has private entrance, equipped kitchen, 1BA, modernly furnished 1BR and living room. It is ideal for visiting Little Saigon (5 mins), SoCal beaches (15 mins), theme parks such as Disneyland (20 mins) coming from LAX (30 mins) or John Wayne Airport ( 14 mins). Minutes from Asian Garden Mall (PLT), Korean Garden Grove town, Bella Tera, Pacific City, Knott Berry Farms, Disney downtown etc.

Top guest favorite
A neatly organized kitchen features dark blue cabinets and light countertops, enhancing the functional space. Stainless steel appliances, including a gas range and microwave, are prominently displayed. A washing machine is positioned to one side, offering convenience for guests.
Guesthouse in Santa Ana
4.99 out of 5 average rating, 185 reviews

Near Disney, Private, Fast Wifi, Self Check-in

Private Guesthouse in the Heart of Orange County! Enjoy your own peaceful retreat in this newly built, detached guesthouse nestled in a quiet residential neighborhood. This bright and modern space offers complete privacy with its own entrance and a fully fenced patio—perfect for morning coffee or evening relaxation. Centrally located in Orange County, you’ll be just a short drive from top attractions, beaches, shopping, and dining, while still enjoying a calm, cozy place to unwind.

Top guest favorite
Guesthouse in Costa Mesa
4.95 out of 5 average rating, 699 reviews

Relax and revive at THE OASIS Poolside Bungalow

Relax, reset and revive in this chic and contemporary poolside bungalow with your own private pool and spa. The attention to detail in this mini-retreat will make you feel right at home. Lay out in sun or take a dip in the pool during the day and sit in the revitalizing spa at night. The bungalow is located within miles of many major attractions in OC such as Newport, Huntington and Laguna beaches, Disneyland, hiking trails and OC Fairgrounds. 2 guests maximum and NO PARTIES PLEASE

Guest favorite
An outdoor seating area is set beneath a covered deck, featuring a cozy sofa and two armchairs arranged around a coffee table. A patterned area rug brings warmth to the space, with panoramic views visible through the railing.
Guesthouse in Fullerton
4.96 out of 5 average rating, 541 reviews

Aviary with Amazing Views!

Perched on a hilltop with Amazing Views, Our place is walking distance from CSU of Fullerton and Fullerton Arboretum. We are located off the 57 fwy and a 20 min drive to Disneyland! It is a tiny cottage with modern amenities and although the cottage is detached from the main home, there is a cottage directly below, where you may hear noise if occupied. You may never see us, but available if needed. Enjoy a tranquil space with sounds of morning birds, outdoor fountains and a dog!

Top guest favorite
A well-lit sleeping area features a spacious bed with decorative pillows and a neutral-toned headboard. Bedside tables with lamps are positioned on either side. A desk is situated against one wall, complemented by shelves displaying decor items, hats, and a sunflower.
Guesthouse in Long Beach
4.94 out of 5 average rating, 398 reviews

Cozy Long Beach guest house with hot tub

Local touches abound inside this cozy guest house. Yard is complete with seating and fire pit, relax and enjoy a glass of wine or soak away the day in the hot tub! This guesthouse is a quaint and comfortable stop for travelers looking for value and convenience in a safe neighborhood. Located close to SoFi stadium, Disneyland, Long Beach airport and LAX and with many great restaurants to choose from. The house is also just a short drive to the beach and downtown Long Beach.

Top guest favorite
The living area features a comfortable tan leather sofa paired with a woven storage ottoman. Natural light pours in through expansive sliding doors, leading to a private patio. A staircase with a black railing elegantly ascends beside the textured gray wall.
Guesthouse in Santa Ana
4.99 out of 5 average rating, 222 reviews

D'Loft By JC

D'Loft is newly built in July 2023. Your family will be close to everything when you stay at this centrally-located place. We are located 10-15 Min from Disneyland, the beach, shopping and much more! D'Loft features an open concept design, dressed in high end appliances and it's own private patio. Relax in a comfy Cal King Bed in addition to a queen size sofa bed + a twin sleeper, available at your disposal. Open the double sliders and make indoor outdoor space!

Top guest favorite
A cozy sitting area features a day bed adorned with soft, neutral-colored pillows. A decorative chest sits in front, complemented by warm wall sconces. Light enters through the windows, illuminating the shiplap walls and wooden accents that enhance the inviting space.
Guesthouse in Fullerton
4.96 out of 5 average rating, 683 reviews

The Lemondrop Cottage

This is the most charming tiny studio cottage with separate entrance, and a private brick patio in a family friendly neighborhood in Sunny Hills Fullerton, and is a short drive to great restaurants, and lots of activities including Disneyland and Knotts Berry Farm. Tucked away at the back of our home, affording guests ample privacy, and easy parking for one car on the driveway. Please note our place is tiny just as we advertise it as.

Superhost
A well-equipped kitchen features modern appliances, including a retro-style black fridge and a gas stove. Open shelves display copper cookware and potted plants. A compact wooden table is set with ceramic cups, and a sink is positioned under a window, offering a view of the outdoor greenery.
Guesthouse in Washington Square
4.92 out of 5 average rating, 344 reviews

The Casita Blanca, Private Guesthouse near Disney

Welcome to the Casita Blanca, located in the heart of sunny Orange County. The detached guesthouse, a private and quiet space, has a Spanish charm and is walking distance from the restaurants and shops in Downtown Santa Ana Arts District. It is located just 5 miles from Disney, 12 miles from beaches, 6 miles from John Wayne Airport and 40 miles from LAX. The casita is comfortable for 4 people with one queen bed + a full size pull out.

Guest favorite
Guesthouse in Anaheim
4.94 out of 5 average rating, 186 reviews

Charming Studio Guesthouse, Ideal for OC Getaways

Design refresh in progress! Our studio has all you need for a wonderful vacation as a solo traveler or with a loved one. This is a brand-new guesthouse with two other units on the property, both available to book on Airbnb. Built with love and care, indulge in the luxury of a roomy walk-in closet, a refreshing en-suite bathroom, and a well-stocked kitchen. There is also a combo washer/dryer for your convenience.

Guest favorite
A modern kitchen showcases light wood cabinetry and a white countertop. Two black bar stools are positioned at the island, which features a small floral arrangement and a bowl of oranges. Overhead, blue pendant lights provide gentle illumination, enhancing the space's contemporary feel.
Guesthouse in Santa Ana
4.89 out of 5 average rating, 142 reviews

Minimalist Modern House

1bed, 1bath, kitchen & living room. 1 gated parking space. For security purposes, the address in Santa Ana is proximate. Exact address in Garden Grove (2.0 miles away) will be sent after booking confirmed. Tesla level 2 charger is available as $25/day/car. The third guest fee is $35/night (sofa bed is available) Sauna self service is available is available at $30 for 2 hours. Please let us know if you need.

Popular amenities for Santa Ana guesthouse rentals

When is the best time to visit Santa Ana?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceG$26,167 GYDG$26,167 GYDG$25,330 GYDG$23,655 GYDG$25,120 GYDG$26,167 GYDG$27,004 GYDG$25,958 GYDG$24,074 GYDG$27,214 GYDG$27,004 GYDG$27,004 GYD
Avg. temp14°C14°C16°C17°C19°C20°C23°C24°C23°C20°C17°C14°C

Quick stats about guesthouse rentals in Santa Ana

  • Total vacation rentals

    Explore 80 vacation rentals in Santa Ana

  • Nightly prices starting at

    Santa Ana vacation rentals start at G$10,467 GYD per night before taxes and fees

  • Verified guest reviews

    Over 7,650 verified reviews to help you choose

  • Family-friendly vacation rentals

    20 properties offer extra space & kid-friendly amenities

  • Rentals with dedicated workspaces

    40 properties have a dedicated workspace

  • Wi-Fi availability

    80 of Santa Ana vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Santa Ana rentals

  • 4.8 Average rating

    Santa Ana stays are highly rated by guests—averaging 4.8 out of 5!

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