Guesthouse vacation rentals in Santa Ana

Find and book unique guesthouse rentals on Airbnb

Quick stats about guesthouse rentals in Santa Ana

  • Total vacation rentals

    Explore 80 vacation rentals in Santa Ana

  • Nightly prices starting at

    Santa Ana vacation rentals start at G$4,183 GYD per night before taxes and fees

  • Verified guest reviews

    Over 8,930 verified reviews to help you choose

  • Family-friendly vacation rentals

    20 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 10 rentals that welcome pets

  • Rentals with dedicated workspaces

    30 properties have a dedicated workspace

  • Wi-Fi availability

    80 of Santa Ana vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Santa Ana rentals

  • 4.9 Average rating

    Santa Ana stays are highly rated by guests—averaging 4.9 out of 5!

Top-rated guesthouse rentals in Santa Ana

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Top guest favorite
A modern living area features a light-colored sofa and a wooden coffee table placed on a soft area rug. In the background, a dining table with chairs is visible, alongside a well-equipped kitchen with wooden cabinets. Natural light brightens the space through large windows.
Guesthouse in Santa Ana
4.97 out of 5 average rating, 210 reviews

Cozy 2-bedroom private guesthouse near South Coast

Step into this getaway house, away from all the hustle and bustle of daily life. You will find calmness and peace on your vacation. Indulge in a hot cup of coffee under the patio in a quiet environment or make your family a hot breakfast in the new kitchen before you head out to nearby attractions. Just bring your sun glasses and luggages. 5 minutes from South Coast Plaza. 25 Minutes from Disneyland Park. 20 minutes from all beautiful beaches, shopping centers and top restaurants of the region.

Top guest favorite
A spacious living area is showcased, featuring a white sofa adorned with yellow accent pillows. A warm brown lounge chair complements the neutral decor. A round mirror reflects natural light, while a small plant adds a touch of greenery to the welcoming atmosphere.
Guesthouse in Costa Mesa
4.96 out of 5 average rating, 295 reviews

Sunny Days - A Bright and Cheerful Guesthouse

Sunny Days is a beautiful and spacious 600 sq. ft. studio apartment with a private entrance and patio. You'll love the bright and airy space, complete with 10-foot ceilings! In the evenings, relax with a glass of wine in the cozy private patio, grilling dinner on the BBQ, and hanging around the gas fire pit. We are centrally located to Newport Beach, John Wayne Airport, and Disneyland. Only a short walk to TeWinkle Park and the OC Fairgrounds. Easy free street parking in a lovely neighborhood.

Top guest favorite
A comfortable living area features a light-colored sofa adorned with decorative pillows. A medium-sized television is positioned on a sleek wooden console. Large windows allow natural light to fill the space, offering views of surrounding greenery, while a wooden coffee table rests in front.
Guesthouse in Santa Ana
4.95 out of 5 average rating, 1418 reviews

Quiet Peaceful Studio

Private studio apartment. Second-story unit, set back from the street, in a separate building behind the hosts' home. Located in a beautiful historic neighborhood, on a quiet street shaded by oak trees. Disneyland and the Anaheim Convention Center are only 10 minutes away. The Honda Center and Anaheim Stadium 5 minutes. The beaches are an easy 20 minute drive. Excellent restaurants and shopping are abundant. Close to Old Town Orange, Chapman University, and the Santa Artists Village.

Top guest favorite
A modern seating area features a sleek black futon flanked by accent pillows, accompanied by two small tables. A decorative wall hanging adds texture above the sofa, while a large, natural wood-framed mirror reflects the space. Potted plants bring a touch of greenery to the decor.
Guesthouse in Anaheim
4.94 out of 5 average rating, 294 reviews

The Cortez Studio Loft

Enjoy your stay in Orange County, CA in this cozy, newly remodeled studio loft! This loft is centrally located in Anaheim. Minutes from amusement parks, beaches, and tons of Southern California attractions. We are a short drive to Downtown LA and the Local Mountains. Wifi and parking included. - Disneyland / Knotts berry farm/ Anaheim Convention Center: 10 minutes drives - Angels Stadium/ Honda Center: 15-minute drive - Downtown LA: 35-minute drive Find us on Instagram: @thecortezloft

Guest favorite
The spacious studio features a queen-size bed framed by minimalist decor. A comfortable sofa bed is positioned opposite a sleek coffee table. Large windows bring natural light into the room, while a stylish light fixture adds a modern touch to the space.
Guesthouse in Santa Ana
4.91 out of 5 average rating, 284 reviews

Lux Upper-Level Guest House 3mi to Disney Magic

Step into our inviting and snug haven! Our AirBnB is for anyone seeking a practical and budget-friendly lodging option. Situated in a secure and welcoming community, it offers seamless access to public transit and a plethora of eateries, coffee houses, and stores. Additionally, it's strategically placed near popular spots like Disney, Knotts Berry Farm, and Angel Stadium. Be it a work trip or a leisurely escape, our AirBnB promises a cozy abode away from home. We can't wait to host you!

Superhost
Guesthouse in Santa Ana
4.8 out of 5 average rating, 106 reviews

Ice Cold A/C | 15 min to Disneyland | Peace & Cozy

Escape to a charming studio that blends rustic warmth with modern comfort perfectly designed for couples, solo travelers, or small families looking to explore the best of Orange County. Radiating rustic elegance, the space is a harmonious blend of tranquility and convenience. Discover the best of Orange County, with top attractions, dining, and shopping just moments away. Perfect for: • Disneyland getaways • Beach weekends • OC food adventures • Business travelers • Couples’ retreats.

Top guest favorite
A neatly organized kitchen features dark blue cabinets and light countertops, enhancing the functional space. Stainless steel appliances, including a gas range and microwave, are prominently displayed. A washing machine is positioned to one side, offering convenience for guests.
Guesthouse in Santa Ana
4.99 out of 5 average rating, 223 reviews

Near Disney, Private, Fast Wifi, Self Check-in

Private Guesthouse in the Heart of Orange County! Enjoy your own peaceful retreat in this newly built, detached guesthouse nestled in a quiet residential neighborhood. This bright and modern space offers complete privacy with its own entrance and a fully fenced patio—perfect for morning coffee or evening relaxation. Centrally located in Orange County, you’ll be just a short drive from top attractions, beaches, shopping, and dining, while still enjoying a calm, cozy place to unwind.

Top guest favorite
A spacious bedroom features a king-size bed with decorative pillows and a throw blanket. Soft, neutral curtains frame large glass doors leading to an outdoor patio, and warm wall sconces illuminate the room. Nightstands are positioned on either side of the bed.
Guesthouse in Santa Ana
4.98 out of 5 average rating, 128 reviews

Cozy 1BR-KingBed+SofaBed 6mi Disney 1.6mi Hosp

Luxury Unit with King-Size Bed, Relax and unwind in our fully equipped unit. With everything you need for a comfortable and enjoyable stay, you're sure to have a memorable time. The unit features: Spacious bedroom with a king-size bed, 54" TV, and a Desk. The Living-room has a sofa bed, making it the perfect place to relax. The kitchen is fully equipped with everything you need. Whether you're on a business trip, vacation, or simply need a place to stay for a few nights.

Top guest favorite
Guesthouse in Santa Ana
4.96 out of 5 average rating, 112 reviews

15 min Disney/SNA Airport - Cozy, Safe Studio Apt

Welcome to the perfect stay for solo or couple travelers. Cozy studio, centrally located within 15 mins of main Orange County tourist destinations! *CENTRALLY LOCATED* + Miles Square Park (2mi) + Asian Garden Mall/Phuoc Loc Tho (2mi) + Anaheim Convention Center (4mi) + The Observatory (4mi) + Disneyland (6mi) + South Coast Plaza (6mi) + Angel's Stadium (8mi) + OC Fairgrounds (8mi) + John Wayne/SNA Airport (9mi) + Knott's Berry Farm (10mi) + Huntington Beach Main St. (10mi)

Top guest favorite
The living area features a comfortable tan leather sofa paired with a woven storage ottoman. Natural light pours in through expansive sliding doors, leading to a private patio. A staircase with a black railing elegantly ascends beside the textured gray wall.
Guesthouse in Santa Ana
4.99 out of 5 average rating, 269 reviews

D'Loft By JC

D'Loft is newly built in July 2023. Your family will be close to everything when you stay at this centrally-located place. We are located 10-15 Min from Disneyland, the beach, shopping and much more! D'Loft features an open concept design, dressed in high end appliances and it's own private patio. Relax in a comfy Cal King Bed in addition to a queen size sofa bed + a twin sleeper, available at your disposal. Open the double sliders and make indoor outdoor space!

Top guest favorite
A remodeled studio space features a large bed with a geometric patterned blanket. A kitchenette is visible in the background, equipped with modern appliances. A dining table is set for two, and the space is well-lit by overhead lights and natural light from nearby windows.
Guesthouse in Orange
4.94 out of 5 average rating, 440 reviews

Studio Near Disneyland With King Bed

Large remodeled Studio near Disneyland & Anaheim Convention Center, Anaheim Honda Center/Stadium, UCI Medical Center, Chapman University, Orange circle. A very high end Serta CalKing size bed. Full kitchen. Private bathroom. Easy access to freeways. Closed to Target, restaurants, In and out bugert and super market. Nice and quiet neighborhood. Free parking. Watch 4th of July fireworks from your suite. Two nights minimum.

Top guest favorite
A modern kitchen showcases light wood cabinetry and a white countertop. Two black bar stools are positioned at the island, which features a small floral arrangement and a bowl of oranges. Overhead, blue pendant lights provide gentle illumination, enhancing the space's contemporary feel.
Guesthouse in Santa Ana
4.91 out of 5 average rating, 194 reviews

Minimalist Modern House

1bed, 1bath, kitchen & living room. 1 gated parking space. For security purposes, the address in Santa Ana is proximate. Exact address in Garden Grove (2.0 miles away) will be sent after booking confirmed. Tesla level 2 charger is available as $25/day/car. The third guest fee is $35/night (sofa bed is available) Sauna self service is available is available at $30 for 2 hours. Please let us know if you need.

Popular amenities for Santa Ana guesthouse rentals

When is the best time to visit Santa Ana?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceG$26,565 GYDG$27,611 GYDG$27,402 GYDG$23,637 GYDG$25,101 GYDG$26,147 GYDG$26,983 GYDG$25,938 GYDG$24,055 GYDG$24,892 GYDG$25,938 GYDG$28,239 GYD
Avg. temp14°C14°C16°C17°C19°C20°C23°C24°C23°C20°C17°C14°C

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