
Guesthouse vacation rentals in San Luis Obispo County
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in San Luis Obispo County
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for San Luis Obispo County guesthouse rentals
Family-friendly guest house rentals

California central coast 2-bedroom haven
This is such a special place. My only regret is that we didn’t stay longer! It’s a perfect central location - close to SLO, Paso Robles, Los Olivos, etc. We loved hearing the chickens in the morning, walking through the garden and enjoying the hot tub/pool amenities. If you’re looking for a relaxing getaway, this is the place for you!!

Wine Country Casita
Bruce and Karen were very responsive and accommodating. Our plans changed and they worked with us. Very friendly. Loved the outdoor area for hanging out on a beautiful day.

Wine Country Bungalow w/ Pool, Spa
We had a fantastic getaway at Jeff's bungalow. The pool and yard were absolutely gorgeous and the bungalow was perfect for us. Comfortable, spacious, and so clean. The stars at night were so clear, and in the morning, so many birds to watch while sipping coffee--I just want to live in that peaceful world. We loved it! Jeff was friendly and quick to respond. I do hope to return again next year.

Private, serene studio near beach & wineries
We enjoyed our stay here. The studio was attractive and clean, the bed, very comfortable. Eric and Holly were very friendly, accommodating and helpful. We enjoyed the quiet, rural setting of the property, with the horse, Bella, dog Lila (that loved belly rubs) and several goats. The place is a short, easy drive from Arroyo Grande and Pismo Beach, and is only 20 minutes from SLO.

Petite Barn
Best Airbnb I’ve ever stayed at. I wanted to find a place I could both swim and relax, this was perfect. I felt very welcomed and comfortable. The room was clean and I had everything I needed. It is the perfect size for me, my husband, and my 3 month old. The pool and backyard was breathtaking. Most beautiful pool I’ve ever swam in. I didn’t wanna leave! Close to wineries and great restaurants in the village.

The Lincoln Street Cottage | SANITIZED & SAFE!
We enjoyed our stay here! The pull-out couch in the living space was perfect for my son (13-years) and my daughter (17 years) and I shared the comfy queen bed. The location was quiet and convenient to Cal Poly, SLO shops/restaurants, and to Avila Beach. Street parking was easy right in front of the unit, too. The unit was very clean and had all the amenities needed when you want a kitchen (coffee, tea, salt/pepper, olive oil spray, honey, pots/pans, glasses, plates, utensils, toaster oven, stove, microwave, etc.). We would definitely would return!

Quaint cottage close to beach
Very hospitable host that is very helpful from before the check-in to the check out. When I come back I’ll definitely try to stay here again.

Windmill Lane-Beautiful Country Tree-Lined Retreat
Jennifer and Eric were great host. Super responsive with messaging. The house was just like the photos and loved having the patio with covering. The surrounding trees help keep it cool even when the days were hot. The wildlife was a bonus seeing all the deer and turkeys running around. Great place to stay! Definitely recommend!
Guest house rentals with a patio

San Luis Obispo Studio, 8 min walk to downtown
A great place to stay. Safe, comfortable for 3, and walkable to neighborhood and downtown restaurants, shops, and Thursday night market. Although there is road noise, it it minimal at night and it did not bother us even with windows open. We’d stay here again.

The Cozy Casita
Love the private space. The location is just what we are looking for.

Creekside guest house in SLO's historic district
Perfect place to stay in SLO. Beautiful, well equipped home in an excellent location. Kate's communication was clear and helpful. Highly recommend.

The Shed
Tayrn and Brian were gracious and accommodating hosts! Room was clean and very private. Morro Bay and Hearst Castle were an easy drive from this place. Definitely worth a stay if you're doing a Central Coast trip.

Unique Studio in Downtown SLO
Very easy check in and looks like the pictures. Great small space which was perfect for our one night stay for a wedding in SLO. Free parking outside was convenient. Thank you!

Central Coast Cottage
Enjoyed our time. Perfect location for exploring the area. Highly recommend!

Deerfield Cottage on Paso's wine road
Monica's home is one of those perfect spots that you feel lucky to find! It is so peaceful and serene, but it is still close to everything. We loved the private deck where we grilled out and enjoyed being surrounded by all the gorgeous flowers, hummingbirds and deer. The inside is very comfortable and very clean. There really is everything you need provided. I would say that my husband and I are slightly high maintenance travelers. We travel a lot, and we can be disappointed if the bedding isn't good, or the bathroom isn't functional, etc. But when we find a place with this much charm, we could have been comfortable no matter what. Luckily it wasn't an issue, because everything was lovely, the bed was super comfortable, and we were just very pleased. We were in town for Cal Poly graduation, but we enjoyed some great activities in the area as well. We went to Sensorio, hiked Big Sur, and visited Cambria and Morro Bay Golf Club. I highly recommend Monica's home to enjoy this fun area!

McClellan Cottage - centrally located studio
This was a great spot as a home base for getting around the Paso Robles area. Comfortable for me and my friend and super spacious. It was really well-decorated and thoughtfully furnished. Casey was also so kind to send me some clothes that were accidentally left there. Highly recommend this spot!
Guest house rentals with a washer and dryer

Studio on Oak
We enjoyed our stay here. Loved the location, it was very walkable. The unit was cozy and comfortable and the area was quiet and seemed safe. Having a washer and dryer was a nice bonus.

Bright, Airy and Beautifully Built!
A great spot to stay on a visit to Paso Robles! Located on a nice quiet street, but easy walking distance to downtown. The home was very thoughtfully presented with details like bath robes, nightlights in the hall and bathroom, essential kitchen, bathroom and laundry items available. The baby cot was set up for us when we arrived, which was also nice after a long journey. We felt very comfortable during our stay. Thanks for hosting!

Crooms Moonlight Ranch, Views and Amazing Sunsets!
We loved our stay at Croom’s Moonlight Ranch! It was a great getaway for a long weekend for my husband and our daughter. The views are amazing and the space was a perfect size for us. Kathy was very responsive and helpful as we planned our trip - it was also so nice to have fresh eggs and delicious pumpkin spice muffins upon arrival! We enjoyed local wineries, including Chateau Margene and Union Sacré, and then returning for some pool time in the afternoon. Thank you for letting us enjoy your beautiful home!

Winemaker's Rural Hideaway in the Heart of Paso Robles
Great location and wonderful cottage. Paso Robles has heaps of restaurants which were fantastic all within between a 15 and 25 minute walk. Jason has his own winery and is a wine maker. We were invited to a wine tasting and bought 4 bottles, each a different selection from the 6 we tried although we would have bought the other 2 as well if we had luggage space. It was some of the best wine we had ever tasted in California.

Cozy Barn in Wine Country
My family and I stayed at Tony and Caron’s barn and had a wonderful time. The space was clean, comfortable, and well-stocked with everything we needed. Our girls especially loved exploring the farm and meeting the animals—it was such a joy to watch them bop around and take it all in. The farm itself, along with the surrounding area, is absolutely beautiful. Peaceful, scenic, and a perfect change of pace. We’re already looking forward to staying here again the next time we’re in Paso!

Maverick Bungalow
The place was quiet, clean & cozy, with beautiful nature all around. However, it was a bit remote so if all activities are planned in Paso Robles, it’s a great find. However, we had family events in SLO, which was about a 45 min drive & that wasn’t so easy, especially at night. The twin mattress was not as nice as the queen bed & it would be nice if the host can provide a hot pot or kettle for warming up water for tea. Other than that, we were really satisfied with the place.

Rustic Rural Ranch House
This place was absolutely amazing! Between the view the homey feel and the lovely hosts we felt that this trip was overall incredible. The sky at night is a huge plus!! The bed was very comfortable and the kitchen was very well stocked and easy to use. We will definitely be going back when we get the chance! So peaceful!

Central Coast Guest House - Private entrance
Mathew and Julie were great hosts. We were so grateful to be able to spend time visiting family in the area and have a great little cottage to come home to. The place was very clean, and Mathew was very responsive and helpful. Thank you for the great stay!
Destinations to explore
- Rentals with a fire pit San Luis Obispo County
- Rentals with a patio San Luis Obispo County
- Cottage rentals San Luis Obispo County
- Villa rentals San Luis Obispo County
- Tiny house rentals San Luis Obispo County
- RV rentals San Luis Obispo County
- Rentals with a washer and dryer San Luis Obispo County
- Family-friendly rentals San Luis Obispo County
- Waterfront rentals San Luis Obispo County
- House rentals San Luis Obispo County
- Private suite rentals San Luis Obispo County
- Rentals with breakfast San Luis Obispo County
- Farmstay rentals San Luis Obispo County
- Rentals with pools San Luis Obispo County
- Rentals with beach access San Luis Obispo County
- Rentals with outdoor seating San Luis Obispo County
- Rentals with a hot tub San Luis Obispo County
- Kid-friendly rentals San Luis Obispo County
- Rentals with lake access San Luis Obispo County
- Apartment rentals San Luis Obispo County
- Hotel rentals San Luis Obispo County
- Condo rentals San Luis Obispo County
- Pet-friendly rentals San Luis Obispo County
- Townhouse rentals San Luis Obispo County
- Bed and breakfasts San Luis Obispo County
- Rentals with a fireplace San Luis Obispo County
- Beachfront rentals San Luis Obispo County
- Rentals with an EV charger San Luis Obispo County
- Rentals with a kayak San Luis Obispo County
- Guesthouse rentals California
- Guesthouse rentals United States
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Cayucos Beach
- Cayucos State Beach
- Morro Strand State Beach
- Montaña de Oro State Park
- Natalie's Cove
- Dairy Creek Golf Course
- B & E Vineyard & Winery
- Pismo State Beach
- Hearst San Simeon State Park
- Wall Beach
- Mission San Luis Obispo de Tolosa
- Allegretto Wines
- Pirates Cove Beach
- Spooner's Cove
- Morro Bay Golf Course
- Moonstone Beach
- Morro Rock Beach
- Point Sal State Beach
- Paradise Beach
- Olde Port Beach
- Au Bon Climat
- French Camp Vineyards
- Bovino Vineyards
- Bianchi Winery
- Things to do San Luis Obispo County
- Food and drink San Luis Obispo County
- Nature and outdoors San Luis Obispo County
- Things to do California
- Wellness California
- Nature and outdoors California
- Food and drink California
- Art and culture California
- Sports activities California
- Sightseeing California
- Entertainment California
- Tours California
- Things to do United States
- Sports activities United States
- Nature and outdoors United States
- Art and culture United States
- Wellness United States
- Tours United States
- Food and drink United States
- Sightseeing United States
- Entertainment United States