
House vacation rentals in San Luis Obispo County
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Top-rated house rentals in San Luis Obispo County
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Boutique Bungalow San Luis Obispo
Go green in this immaculately maintained mid-century modern bungalow. The solar electric power includes a 50A Tesla car charger for guest use, while the yard features a low-water, Japanese bamboo and zen-influenced design. We maintain a low allergen environment. The home is professionally cleaned and extra care has been taken to ensure that the entire place has been disinfected as your well-being is our top priority. There is a shared wall with the owners residence but the entire yard and front house are for guest use. Remodeled, clean, contemporary, well appointed 1000 sq. ft. home with two king bedrooms, two bathrooms, full size kitchen, laundry, sunny front patio and private back courtyard. Fully remodeled, clean, contemporary, well appointed 1000 sq. ft. home. One on street and one off street parking space. Open kitchen, high end stainless appliances, spacious living room, cable television, high speed wifi, master king bedroom with sleep number bed, full contemporary bath & second king bedroom. Laundry room, storage, bike shed. Back patio with private dining and mature bamboo / zen landscaping. South facing, sunny front porch with view of Madonna Mountain. Full front house, private courtyard, front patio, storage shed, parking for two vehicles (one large on street with permit and one small off street) and full size laundry. Interaction with guests depends on owners schedule. Owners have a separate (connected) residence on the same property. This quiet neighborhood is in the "banana belt" part of town. Characteristically warmer than other locations and less wind. Quiet, residential, wide street. Great views. Easy access. Close to Cal Poly, downtown, and outdoor activities. Three blocks from Cal Poly. 0.5 miles from trolly to downtown. Ten minute bike ride to Higuera Street. Hiking, trail running, mountain biking and road cycling out the front door! Athletes, professors, professionals and individuals who enjoy four star hotel properties! Guests have full use of the front patio, private courtyard and access to the back yard. There is one in street parking permit for guest use and off street parking for one mid sized car off the drive way. Owners travel regularly and if our of town have a local manager and handyman who can assist with any issues. This is a quiet neighbourhood, primarily made up of college professors, professionals, students, and retirees, a few blocks from Cal Poly. The house is on a low-traffic street, with parks plus hiking and biking trails nearby. Restaurants and stores are within easy walking distance. Morro Bay, Montaña de Oro State Park, Pismo Beach, Avila Beach, hiking and mountain bike trails, and 240 wineries are within 30 minutes drive. There is parking available for two cars, one (mid-size or smaller) off street and one on street parking permit. Free weekend street parking for any number of vehicles (10:00 pm Friday - 2:00 am Monday.) The house is not set up for children as there are breakable art pieces within reach and no safety devices on cupboards. Chemicals and pest deterrents are in unsecured cupboards. One off street parking space for a mid sized car is provided on the paved area off the driveway. One on street is provided with a guest permit. Transient Occupancy Registration Certificate: 112526 Business License / Home Stay Permit: 112735 For more information on Things To Do in San Luis Obispo, visit https://www.slocal.com
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4.5 Acre Farmhouse in Wine Country w/Hot Tub
Come unwind on this gated 4.5-acre retreat, newly built in 2019! Located in the heart of the Templeton Gap wine region — with wineries just down the street — you’ll be minutes from both downtown Templeton and Atascadero. Relax on the spacious 500 sq. ft. patio and take in the sweeping views while enjoying a BBQ, sipping local wine, playing lawn games, or soaking in the hot tub under the stars. Inside, the game room offers darts, pool, ping pong, Connect 4, Pop-A-Shot, and more for family fun!
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Cozy Studio Close to Downtown SLO
Cozy Studio is located in a quiet residential neighbor with secure off street parking. Whether you choose to relax in my comfortably furnished studio or enjoy the private outdoor patio, my home will provide a serene retreat. From the house, it is a ten minute walk to downtown. Home features smart tv with Netflix, Hulu, and Sling. It also features high-speed wifi and air conditioning. Please note that the bedroom is upstairs and the bathroom is downstairs . Home Stay Permit # 0235-2020
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Spacious SLO Retreat | Walk to DT/Parks
This brand new home is located just a few blocks away from the charming Railroad District in San Luis Obispo, where you'll discover a host of incredible restaurants and delis. Situated in a peaceful residential neighborhood, this fully equipped 2 bed, 1.5 bathroom home offers the perfect escape. The living room opens up to a stunning deck with a spectacular view of Madonna Mountain, complete with a BBQ and dining table so you can soak up the incredible Central Coast weather.
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Upscale. Pet friendly. Great location! 6-10 guests
Welcome! This 4/2 fully upgraded, Spanish Med. in D/T SLO is filled with ambiance! Hotel-grade queen beds and furnishings suit up to 10 perfectly. Formal or gazebo dining, fire pit/BBQ, and games area. 2 car driveway parking. Easy self-entry. Complimentary drink on arrival! Clean quiet house trained pets Ok! 20 mins to beaches/wineries. Includes a detached bungalow/master suite with 1/2 bath. A quality spot for entertaining, or to relax in. You’ll LOVE it here~
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Cozy, Clean and Close to downtown SLO!
Relax in my comfortably furnished, air conditioned (a rare amenity in SLO), 3 bedroom home. Located in a quiet, residential neighborhood with secure, off-street parking. Multiple indoor and outdoor living spaces will provide a quiet retreat for everyone! My home features Air-conditioning, soft water, reverse osmosis drinking water, a record player with vinyl collection and games. WiFi, Sling TV, Netflix & Hulu! Business Lic # 113276. Home Stay Permit # 0235-2020
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Serenity On Serrano
Serenity on Serrano is a Frank Lloyd Wright-inspired peaceful haven set in one of SLO's most prestigious neighborhoods right on the edge of a creek. This midcentury modern home is just steps to hiking, the downtown, shopping, and restaurants. Be prepared for nature as it's common to be greeted by wild turkeys, birds, and more. Enjoy the tranquility of minimalist design. Note: There is $25 per night for each extra guest over 4. Permit # H-0408-2023
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SLO Vibes
Enjoy a stylish experience at this centrally-located place with a contemporary design and panoramic hillside views. Modern all-electric home featuring 2 bedrooms and 2.5 bathrooms is ideally located just minutes from Downtown San Luis Obispo and Edna Valley Wine Country. Step into a modern kitchen, and private balcony off the heart of your living space. Both bedrooms have ensuite bathrooms. 2-car garage. Hope you soak in this vibrant home!
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Cozy Retreat Walking Distance to Downtown
This historic home has been recently remodeled. It sits in a quiet, friendly neighborhood which is walking distance to downtown. The second bedroom overlooks a large, beautiful garden and you can hear the gentle song of frogs at night and church bells in the morning. All beds feature luxury linens and the Wifi is fantastic! Forget your worries in this spacious and serene space. Walking distance to High Street Deli and Village Host Pizza.
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STENNER CREEK RANCH
This is a custom built, fully equipped luxury home on a private 400 acre ranch adjacent to Cal Poly and the San Luis Obispo City limits. Truly one-of-a-kind setting. CAVEAT: The home is located at the end of a 1.5 mile dirt and gravel road. Although the road it maintained by the county, it can get bumpy. Guests with low-clearance vehicles will need to drive slowly and carefully to avoid potholes-especially during the winter months.
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The Downtown House SLO with Private Parking
Charming 1920s bungalow in the heart of downtown San Luis Obispo! Walk to top restaurants, coffee shops, parks, and the famous Farmers Market. Perfect for SLO Marathon runners—just a mile from the starting line. Original details + modern upgrades, A/C, full kitchen, laundry, and parking. Ideal for guests who love vibrant, walkable neighborhoods. We’re locals and happy to share our favorite hikes, wineries, and spots to explore!
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Mid Century Modern Loft Downtown SLO
This unique place has a style all it's own. Mid century modern loft located just a few blocks from downtown SLO. 10 min walk and 3 min drive to all the great shops and restaurants SLO has to offer. Thick glass walls in the bedroom allow for an open loft like experience. Many fun details throughout the place create a truly unique vibe. This 800sf loft located upstairs above a salon is private and has designed parking.
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Popular amenities for San Luis Obispo County house rentals
House rentals with a pool

Gorgeous Hilltop Oasis with Pool and Expansive Views
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Seven Oaks Cottage
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Historic 1895 Edna Railhouse with Heated Pool
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Lux Château, Hot Tub, OutdoorMovies, Game Rm, Pool
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PaSO PaNORAMA-Swimming Pool, Hot Tub, & Views
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Luxury Mountain View Retreat Pool/jacuzzi
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Spacious Getaway w/Hot Tub, Pool, Game Room & More
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Getaway at the Highlands+Heated Pool+Hot Tub
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Weekly house rentals

Central Coast - Creekside Living
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Private, Wooded Home, and a Modern Design
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Contemporary Wine Country Retreat-Walk to Downtown
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NEW Cozy Private House -Near Cal Poly and DT SLO
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Cottage near Cal Poly & Downtown
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Wine Country Hilltop Retreat
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Bayview Getaway
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Bishops Peak Retreat-Spa, Family Friendly!
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Private house rentals

Peaceful home steps to downtown SLO and Cal Poly
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The Cottage on Palm
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By the Bay. Pet friendly, golf, hike, ocean. wine
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Beautiful Country Home
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Family-Friendly 5BR Ranch | Theater+Putting Green
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Pacific Coast Highway Milkhouse
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Place Among the Trees: walk to downtown SLO
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The Los Osos Valley Guest House
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Destinations to explore
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- Cayucos Beach
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- California Polytechnic State University
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- Sensorio
- Mission San Luis Obispo de Tolosa
- Pismo Preserve
- Charles Paddock Zoo
- Monarch Butterfly Grove
- Vina Robles Amphitheatre
- JUSTIN Vineyards & Winery
- Tablas Creek Vineyard
- Downtown City Park
- Niner Wine Estates
- Harmony Headlands State Park
- Talley Vineyards
- Fess Parker Winery & Vineyard
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