House vacation rentals in San Luis Obispo County

4.94 out of 5 average rating, 276 reviews

An outdoor seating area features a modern fire pit surrounded by comfortable wicker sofas. Sunlight illuminates the space, highlighting the natural landscape beyond, which includes trees and rolling hills. Elegant decor is present, providing a welcoming atmosphere for relaxation.

Home in Atascadero

4.5 Acre Farmhouse in Wine Country w/Hot Tub

Come unwind on this gated 4.5-acre retreat, newly built in 2019! Located in the heart of the Templeton Gap wine region — with wineries just down the street — you’ll be minutes from both downtown Templeton and Atascadero. Relax on the spacious 500 sq. ft. patio and take in the sweeping views while enjoying a BBQ, sipping local wine, playing lawn games, or soaking in the hot tub under the stars. Inside, the game room offers darts, pool, ping pong, Connect 4, Pop-A-Shot, and more for family fun!

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The kitchen area features white cabinetry and stainless steel appliances, including a refrigerator and stove. A wooden countertop provides workspace beside a high-top table with seating. The floor is covered in light-colored planks, and a red door is visible in the background leading outdoors.

4.87 out of 5 average rating, 221 reviews

Cozy Studio Close to Downtown SLO

Cozy Studio is located in a quiet residential neighbor with secure off street parking. Whether you choose to relax in my comfortably furnished studio or enjoy the private outdoor patio, my home will provide a serene retreat. From the house, it is a ten minute walk to downtown. Home features smart tv with Netflix, Hulu, and Sling. It also features high-speed wifi and air conditioning. Please note that the bedroom is upstairs and the bathroom is downstairs . Home Stay Permit # 0235-2020

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A modern living area features a dark leather sofa set against warm hardwood floors. A round wooden coffee table holds magazines, while a bookshelf displays various decorative items. Natural light filters in through sliding glass doors, leading to an outdoor space.

4.88 out of 5 average rating, 308 reviews

Boutique Bungalow San Luis Obispo

Go green in this immaculate low allergen mid-century modern 1000 sf bungalow. Solar electric power includes a 50A Tesla car charger while the yard features a low-water, Japanese bamboo design. Open full size kitchen, high end stainless appliances, spacious living room, cable TV, high speed wifi, 2 bed- 2 bath, master king bedroom with sleep number bed, full contemporary bath & second king bedroom. Laundry room, storage, bike shed, private courtyard, sunny patio with great view.

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Superhost

The exterior of the Victorian home showcases charming architectural details. A white picket fence surrounds the property, while vibrant greenery and trees enhance the setting. The inviting front porch features steps leading up to a welcoming entry, with large windows offering natural light.

4.89 out of 5 average rating, 130 reviews

Downtown SLO Victorian+Sleeps 12+Walkable+Private

Charming & spacious early 1900's Victorian home in the heart of San Luis Obispo. Easy 1/2-mile stroll to downtown. This historic treasure has all the characteristics and quirks that make vintage homes so special. It is decorated in a fun and casual way and comfortably sleeps up to 12 guests. Fully stocked retro kitchen with a restored 1954 O'Keefe-Merritt stove. Perfectly set-up to accommodate a large group of friends or family for a memorable trip to the beautiful Central Coast!

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4.94 out of 5 average rating, 142 reviews

San Luis Obispo Wine Country Retreat

Escape to a luxurious three-bedroom farmhouse on a shared 10-acre ranch in San Luis Obispo's Edna Valley, surrounded by rolling hills of renowned vineyards. Newly renovated with modern amenities including a spacious kitchen, cozy living room with smart TV, and private patio with fire pit. Sleeps up to six guests with AC, heating, WiFi, and BBQ grill included. Explore nearby wineries and restaurants or relax on the private patio. Book now for a memorable California getaway.

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4.95 out of 5 average rating, 257 reviews

Upscale. Pet friendly. Great location! 6-10 guests

Welcome! This 4/2 fully upgraded, Spanish Med. in D/T SLO is filled with ambiance! Hotel-grade queen beds and furnishings suit up to 10 perfectly. Formal or gazebo dining, fire pit/BBQ, and games area. 2 car driveway parking. Easy self-entry. Complimentary drink on arrival! Clean quiet house trained pets Ok! 20 mins to beaches/wineries. Includes a detached bungalow/master suite with 1/2 bath. A quality spot for entertaining, or to relax in. You’ll LOVE it here~

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A spacious outdoor seating area is furnished with comfortable wicker chairs and a matching coffee table. Colorful cushions enhance the seating. A patterned rug adds texture beneath the furniture. In the background, a dining table is visible under a large umbrella, with a wall of greenery providing privacy.

4.9 out of 5 average rating, 568 reviews

Cozy, Clean and Close to downtown SLO!

Relax in my comfortably furnished, air conditioned (a rare amenity in SLO), 3 bedroom home. Located in a quiet, residential neighborhood with secure, off-street parking. Multiple indoor and outdoor living spaces will provide a quiet retreat for everyone! My home features Air-conditioning, soft water, reverse osmosis drinking water, a record player with vinyl collection and games. WiFi, Sling TV, Netflix & Hulu! Business Lic # 113276. Home Stay Permit # 0235-2020

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The exterior of the home is framed by vibrant red foliage, with a mix of trees and shrubs surrounding a well-maintained lawn. Large windows provide views into the interior, while a wooden deck extends outward, complementing the natural landscape.

4.86 out of 5 average rating, 143 reviews

Serenity On Serrano

Serenity on Serrano is a Frank Lloyd Wright-inspired peaceful haven set in one of SLO's most prestigious neighborhoods right on the edge of a creek. This midcentury modern home is just steps to hiking, the downtown, shopping, and restaurants. Be prepared for nature as it's common to be greeted by wild turkeys, birds, and more. Enjoy the tranquility of minimalist design. Note: There is $25 per night for each extra guest over 4. Permit # H-0408-2023

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A light-filled living area features a comfortable sofa adorned with decorative pillows. A wooden coffee table with natural elements sits atop a soft area rug, while abstract wall art complements the neutral tones. A modern kitchen is visible in the background, enhancing the open layout.

4.96 out of 5 average rating, 152 reviews

SLO Vibes

Enjoy a stylish experience at this centrally-located place with a contemporary design and panoramic hillside views. Modern all-electric home featuring 2 bedrooms and 2.5 bathrooms is ideally located just minutes from Downtown San Luis Obispo and Edna Valley Wine Country. Step into a modern kitchen, and private balcony off the heart of your living space. Both bedrooms have ensuite bathrooms. 2-car garage. Hope you soak in this vibrant home!

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Superhost

A spacious living area features a plush black couch adorned with decorative pillows. A coffee table with a potted plant sits in front, while a dining area with wooden chairs and a light fixture is visible in the background. Light streams in through multiple windows.

4.76 out of 5 average rating, 233 reviews

Cozy Retreat Walking Distance to Downtown

This historic home has been recently remodeled. It sits in a quiet, friendly neighborhood which is walking distance to downtown. The second bedroom overlooks a large, beautiful garden and you can hear the gentle song of frogs at night and church bells in the morning. All beds feature luxury linens and the Wifi is fantastic! Forget your worries in this spacious and serene space. Walking distance to High Street Deli and Village Host Pizza.

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The exterior of a charming luxury home is set against a backdrop of rolling hills. The structure features a steep roof and natural stone accents, framed by greenery and outdoor landscaping. A gravel pathway leads to the entrance, inviting guests to explore.

4.91 out of 5 average rating, 188 reviews

STENNER CREEK RANCH

This is a custom built, fully equipped luxury home on a private 400 acre ranch adjacent to Cal Poly and the San Luis Obispo City limits. Truly one-of-a-kind setting. CAVEAT: The home is located at the end of a 1.5 mile dirt and gravel road. Although the road it maintained by the county, it can get bumpy. Guests with low-clearance vehicles will need to drive slowly and carefully to avoid potholes-especially during the winter months.

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Top guest favorite

A bright living area features a comfortable sofa and two accent chairs, surrounded by natural light from large windows. A coffee table with a decorative centerpiece sits on a patterned rug, while a flat-screen television is mounted above the fireplace, enhancing the cozy atmosphere.