
House vacation rentals in San Luis Obispo
Find and book unique houses on Airbnb
Quick stats about house rentals in San Luis Obispo

Total vacation rentals
Explore 190 vacation rentals in San Luis Obispo

Verified guest reviews
Over 16,510 verified reviews to help you choose

Family-friendly vacation rentals
120 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 60 rentals that welcome pets

Rentals with dedicated workspaces
90 properties have a dedicated workspace

Wi-Fi availability
180 of San Luis Obispo vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across San Luis Obispo rentals

4.9 Average rating
San Luis Obispo stays are highly rated by guests—averaging 4.9 out of 5!
Top-rated house rentals in San Luis Obispo
Guests agree: these houses are highly rated for location, cleanliness, and more.

New 1 Bedroom House - Great Location in SLO
This is a brand new 1 bedroom house attached to the back of the main house but with a completely separate entrance and is a fully separate unit, think duplex. It is located less than a mile from Cal Poly campus, less than 2 miles from downtown SLO, and is a short drive to local beaches. The deck is tucked next to a beautiful oak tree and is very private setting. Bishops Peak mountain is less than a mile away for a great hike and it also blocks a lot of wind for a warmer experience in SLO.

1884 Elegant Home: Fire Pit, Tesla Tech, Near DT
Step into history at this charming 2-bedroom railroad house in downtown SLO. Enjoy its preserved heritage, from the 11-foot tall ceilings to the spacious kitchen. Sleep luxuriously on Purple mattresses in both bedrooms. Unwind next to the fire pit in the backyard. It's a short 7 min. stroll to downtown & next to 5 restaurants including Sally Lou's coffee shop & the train station. Experience SLO's charm like never before with this perfect location home. Send us a message to plan your trip!

Cozy Studio Close to Downtown SLO
Cozy Studio is located in a quiet residential neighbor with secure off street parking. Whether you choose to relax in my comfortably furnished studio or enjoy the private outdoor patio, my home will provide a serene retreat. From the house, it is a ten minute walk to downtown. Home features smart tv with Netflix, Hulu, and Sling. It also features high-speed wifi and air conditioning. Please note that the bedroom is upstairs and the bathroom is downstairs . Home Stay Permit # 0235-2020

Downtown SLO Victorian+Sleeps 12+Walkable+Private
Charming & spacious early 1900's Victorian home in the heart of San Luis Obispo. Easy 1/2-mile stroll to downtown. This historic treasure has all the characteristics and quirks that make vintage homes so special. It is decorated in a fun and casual way and comfortably sleeps up to 12 guests. Fully stocked retro kitchen with a restored 1954 O'Keefe-Merritt stove. Perfectly set-up to accommodate a large group of friends or family for a memorable trip to the beautiful Central Coast!

Spacious SLO Retreat | Walk to DT/Parks
This brand new home is located just a few blocks away from the charming Railroad District in San Luis Obispo, where you'll discover a host of incredible restaurants and delis. Situated in a peaceful residential neighborhood, this fully equipped 2 bed, 1.5 bathroom home offers the perfect escape. The living room opens up to a stunning deck with a spectacular view of Madonna Mountain, complete with a BBQ and dining table so you can soak up the incredible Central Coast weather.

Gorgeous Hilltop Oasis with Pool and Expansive Views
Feel cares slip away in the serene saltwater pool set among ancient oaks and endless vistas. Enjoy one of Atascadero's most beautiful neighborhoods, sitting atop the Hills of the Central Coast. Morning strolls are a literal walk in the clouds with stunning canyon views and deer roaming nearby. It's hard to believe this property is only 8 minutes from the freeway. This comfortable tri-level four bedroom home is perfectly practical for family or group entertaining.

Serenity On Serrano
Serenity on Serrano is a Frank Lloyd Wright-inspired peaceful haven set in one of SLO's most prestigious neighborhoods right on the edge of a creek. This midcentury modern home is just steps to hiking, the downtown, shopping, and restaurants. Be prepared for nature as it's common to be greeted by wild turkeys, birds, and more. Enjoy the tranquility of minimalist design. Note: There is $25 per night for each extra guest over 4. Permit # H-0408-2023

Wine Country Hilltop Retreat
Kick back and relax in this calm, stylish space with spectacular Edna Valley views. Read a book on your hillside patio and see buffalo and longhorns grazing in neighboring fields. After an incredible sunset, unwind by your firepit at night under a sky full of stars. This private country escape is also at the center of it all - 15 minutes to beaches & Cal Poly, 5 minutes to airport & 20+ wineries/tasting rooms, 10 minutes to beautiful downtown SLO.

SLO Vibes
Enjoy a stylish experience at this centrally-located place with a contemporary design and panoramic hillside views. Modern all-electric home featuring 2 bedrooms and 2.5 bathrooms is ideally located just minutes from Downtown San Luis Obispo and Edna Valley Wine Country. Step into a modern kitchen, and private balcony off the heart of your living space. Both bedrooms have ensuite bathrooms. 2-car garage. Hope you soak in this vibrant home!

The Downtown House SLO with Private Parking
Charming 1920s bungalow in the heart of downtown San Luis Obispo! Walk to top restaurants, coffee shops, parks, and the famous Farmers Market. Perfect for SLO Marathon runners—just a mile from the starting line. Original details + modern upgrades, A/C, full kitchen, laundry, and parking. Ideal for guests who love vibrant, walkable neighborhoods. We’re locals and happy to share our favorite hikes, wineries, and spots to explore!

Mid Century Modern Loft Downtown SLO
This unique place has a style all it's own. Mid century modern loft located just a few blocks from downtown SLO. 10 min walk and 3 min drive to all the great shops and restaurants SLO has to offer. Thick glass walls in the bedroom allow for an open loft like experience. Many fun details throughout the place create a truly unique vibe. This 800sf loft located upstairs above a salon is private and has designed parking.

Family Home Close to Downtown
10min walk to Beautiful Downtown SLO, Awesome coffee shop very close by. The best sandwich shop (high st. Deli) is also nearby. We have a beautiful 3 bedroom family home. Nice sun room dining area with medium sized living room. Front and back yard both are fenced in. Back yard has, Large trampoline, grass area, red wood trees, patio furniture. Front yard has, small grass area, maple tree, patio furniture.
Popular amenities for San Luis Obispo house rentals
House rentals with a pool

Seven Oaks Cottage

Spacious SLO CAL Home w/ Pool, Spa. Pet Friendly!

Getaway at the Highlands+Heated Pool+Hot Tub

Three Sisters Farm Wine Country Home

PaSO PaNORAMA-Swimming Pool, Hot Tub, & Views

Casa Bonnaire Wine Country Oasis

Luxury Mountain View Retreat Pool/jacuzzi

Campover Ranch in Paso Robles - Saltwater Pool
Weekly house rentals

Farmhouse located on San Luis Obispo Central Coast

The Los Osos Valley Guest House

Modern Cayucos Bungalow - Ocean Views and Hot Tub

Beach House ON Pismo Beach

Mid-century home in the heart of Arroyo Grande.

Entire Hobby Farm, Surrounded by Vineyards

The Quailhouse on Ranch near Avila Beach

Hilltop Horizon: Centrally Located+Panoramic Views
Private house rentals

Serene 2BR • Sauna • Cinema • Near Downtown

Boutique Bungalow San Luis Obispo

Downtown Craftsman with Courtyard

Spacious Slo Studio: AirBnB Dream

Coach House Cottage | Firepit | Pet Friendly

Stargazing Studio with Private Deck

Upscale. Pet friendly. Great location! 6-10 guests

Cozy, Clean and Close to downtown SLO!
When is the best time to visit San Luis Obispo?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$47,498 GYD | G$46,452 GYD | G$43,732 GYD | G$50,637 GYD | G$47,917 GYD | G$59,425 GYD | G$56,496 GYD | G$52,729 GYD | G$48,335 GYD | G$48,754 GYD | G$51,683 GYD | G$46,243 GYD |
| Avg. temp | 12°C | 12°C | 13°C | 14°C | 15°C | 16°C | 18°C | 18°C | 18°C | 17°C | 14°C | 11°C |
Destinations to explore
- San Diego Vacation rentals
- Los Angeles Vacation rentals
- San Francisco Vacation rentals
- Palm Springs Vacation rentals
- Big Bear Lake Vacation rentals
- Tijuana Vacation rentals
- San Jose Vacation rentals
- Joshua Tree Vacation rentals
- Mammoth Lakes Vacation rentals
- Long Beach Vacation rentals
- Santa Barbara Vacation rentals
- West Hollywood Vacation rentals
- Beachfront rentals San Luis Obispo
- Rentals with an EV charger San Luis Obispo
- Cabin rentals San Luis Obispo
- Rentals with beach access San Luis Obispo
- Guesthouse rentals San Luis Obispo
- Rentals with pools San Luis Obispo
- Condo rentals San Luis Obispo
- Rentals with outdoor seating San Luis Obispo
- Apartment rentals San Luis Obispo
- Rentals with a fire pit San Luis Obispo
- Pet-friendly rentals San Luis Obispo
- Hotel rooms San Luis Obispo
- Private suite rentals San Luis Obispo
- Rentals with a patio San Luis Obispo
- Rentals with breakfast San Luis Obispo
- Rentals with a hot tub San Luis Obispo
- Family-friendly rentals San Luis Obispo
- Rentals with a fireplace San Luis Obispo
- Rentals with a washer and dryer San Luis Obispo
- House rentals San Luis Obispo County
- House rentals California
- House rentals United States
- Cayucos Beach
- Moonstone Beach
- Pismo State Beach
- Hearst Castle
- Morro Strand State Beach
- Montaña de Oro State Park
- Cayucos State Beach
- Los Padres National Forest
- Morro Rock Beach
- Morro Bay Golf Course
- California Polytechnic State University
- Mission San Luis Obispo de Tolosa
- Dinosaur Caves Park
- Oceano Dunes State Vehicular Recreation Area
- Sensorio
- Pismo Preserve
- Charles Paddock Zoo
- Monarch Butterfly Grove
- Vina Robles Amphitheatre
- JUSTIN Vineyards & Winery
- Tablas Creek Vineyard
- Downtown City Park
- Elephant Seal Vista Point
- Talley Vineyards
- Things to do San Luis Obispo
- Things to do San Luis Obispo County
- Nature and outdoors San Luis Obispo County
- Food and drink San Luis Obispo County
- Things to do California
- Tours California
- Sports activities California
- Food and drink California
- Sightseeing California
- Wellness California
- Nature and outdoors California
- Art and culture California
- Entertainment California
- Things to do United States
- Nature and outdoors United States
- Tours United States
- Sightseeing United States
- Sports activities United States
- Entertainment United States
- Art and culture United States
- Food and drink United States
- Wellness United States







