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House vacation rentals in San Luis Obispo

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Top-rated house rentals in San Luis Obispo

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Top guest favorite
A fresh bedroom features exposed wooden beams and soft lighting. A spacious bed is centered against a wooden headboard, and light filters through a window adorned with subtle blinds. Simple artwork complements the light-colored walls, contributing to a calming environment.
Home in Los Osos
4.99 out of 5 average rating, 169 reviews

Back Bay Getaway - Dog Friendly - Home in Los Osos

Our peaceful home is located a short walk from the back bay of Los Osos. Its new design makes for a restful getaway with its luxurious bedroom, hot tub, and soothing bath. Our home is close to many local favorite hiking, biking, kayaking, surfing, and paddle boarding locations such as Montana de Oro and Morro Bay. The outdoor patio is the perfect setting for a family bbq with a lawn for your pets to play. A short distance away is delicious cuisine, coffee shops, golfing, and local art studios.

Top guest favorite
A newly built 1-bedroom home is set against a backdrop of rolling green hills. The structure features a modern design with a dark exterior and a covered porch area. A small dog sits on the concrete driveway, adding a welcoming touch to the scene.
Home in San Luis Obispo
4.99 out of 5 average rating, 122 reviews

Hilltop Horizon: Centrally Located+Panoramic Views

Newly built,secluded 600 sq ft 1 bedroom home with panoramic views of all of San Luis Obispo. Home is centrally located at 7min from both downtown &/or wineries, 3 miles to Cal Poly- but is completely quiet with no traffic on our multi acre property. This home shares the driveway and parking with our family’s main house, but the home has been designed for the two sets of 8ft glass sliders to have unobstructed views while maintaining complete privacy. We are 15 minutes to Avila and Pismo Beach.

Guest favorite
A modern kitchen is equipped with stainless steel appliances, including a gas range and refrigerator. White cabinetry provides ample storage, while a double window overlooks the sink area. A neutral-toned rug lies on the wooden floor, enhancing the clean, uncluttered appearance.
Home in San Luis Obispo
4.89 out of 5 average rating, 327 reviews

New 1 Bedroom House - Great Location in SLO

This is a brand new 1 bedroom house attached to the back of the main house but with a completely separate entrance and is a fully separate unit, think duplex. It is located less than a mile from Cal Poly campus, less than 2 miles from downtown SLO, and is a short drive to local beaches. The deck is tucked next to a beautiful oak tree and is very private setting. Bishops Peak mountain is less than a mile away for a great hike and it also blocks a lot of wind for a warmer experience in SLO.

Top guest favorite
A backyard patio features a circular fire pit surrounded by comfortable seating. String lights hang overhead, providing a warm glow. Greenery lines the perimeter, and the space is paved with stone tiles, creating an inviting area for relaxation and socializing.
Home in Downtown SLO
5 out of 5 average rating, 188 reviews

1884 Elegant Home: Fire Pit, Tesla Tech, Near DT

Step into history at this charming 2-bedroom railroad house in downtown SLO. Enjoy its preserved heritage, from the 11-foot tall ceilings to the spacious kitchen. Sleep luxuriously on Purple mattresses in both bedrooms. Unwind next to the fire pit in the backyard. It's a short 7 min. stroll to downtown & next to 5 restaurants including Sally Lou's coffee shop & the train station. Experience SLO's charm like never before with this perfect location home. Send us a message to plan your trip!

Guest favorite
The exterior of the home is framed by vibrant red foliage, with a mix of trees and shrubs surrounding a well-maintained lawn. Large windows provide views into the interior, while a wooden deck extends outward, complementing the natural landscape.
Home in San Luis Obispo
4.86 out of 5 average rating, 112 reviews

Serenity On Serrano

Serenity on Serrano is a Frank Lloyd Wright-inspired peaceful haven set in one of SLO's most prestigious neighborhoods right on the edge of a creek. This midcentury modern home is just steps to hiking, the downtown, shopping, and restaurants. Be prepared for nature as it's common to be greeted by wild turkeys, birds, and more. Enjoy the tranquility of minimalist design. Note: There is $25 per night for each extra guest over 4. Permit # H-0408-2023

Guest favorite
A bright and airy living space features a large window allowing natural light to fill the area. The room includes a cozy seating arrangement with a gray sofa, a wooden dining table with chairs, and decorative wall baskets. A kitchenette is visible in the background.
Home in San Luis Obispo
4.96 out of 5 average rating, 341 reviews

Wine Country Hilltop Retreat

Kick back and relax in this calm, stylish space with spectacular Edna Valley views. Read a book on your hillside patio and see buffalo and longhorns grazing in neighboring fields. After an incredible sunset, unwind by your firepit at night under a sky full of stars. This private country escape is also at the center of it all - 15 minutes to beaches & Cal Poly, 5 minutes to airport & 20+ wineries/tasting rooms, 10 minutes to beautiful downtown SLO.

Superhost
A spacious living area features a plush black couch adorned with decorative pillows. A coffee table with a potted plant sits in front, while a dining area with wooden chairs and a light fixture is visible in the background. Light streams in through multiple windows.
Home in Downtown SLO
4.76 out of 5 average rating, 174 reviews

Cozy Retreat Walking Distance to Downtown

This historic home has been recently remodeled. It sits in a quiet, friendly neighborhood which is walking distance to downtown. The second bedroom overlooks a large, beautiful garden and you can hear the gentle song of frogs at night and church bells in the morning. All beds feature luxury linens and the Wifi is fantastic! Forget your worries in this spacious and serene space. Walking distance to High Street Deli and Village Host Pizza.

Top guest favorite
Two wooden loungers with soft cushions are positioned beside a clear swimming pool, inviting relaxation. A small side table sits between the loungers. The pool area is surrounded by a spacious lawn and features well-maintained landscaping.
Home in San Luis Obispo
5 out of 5 average rating, 103 reviews

San Luis Obispo House With Pool And Hot Tub

House in San Luis Obispo with pool! Located 10 minutes from downtown SLO, 15 minutes from the beach, 15 minutes from Cal Poly campus, and in the heart of Edna Valley wine country. This property boasts a large pool and hot tub, beautiful Mountain View’s, and comfortable outdoor living. Have a night around the fire pit, play a game of air hockey, or enjoy the outdoor 75" T.V. There is truly something for everyone at this location..

Top guest favorite
A bright living area features a comfortable sofa and two accent chairs, surrounded by natural light from large windows. A coffee table with a decorative centerpiece sits on a patterned rug, while a flat-screen television is mounted above the fireplace, enhancing the cozy atmosphere.
Home in Downtown SLO
4.96 out of 5 average rating, 423 reviews

The Downtown House SLO with Private Parking

Charming 1920s bungalow in the heart of downtown San Luis Obispo! Walk to top restaurants, coffee shops, parks, and the famous Farmers Market. Perfect for SLO Marathon runners—just a mile from the starting line. Original details + modern upgrades, A/C, full kitchen, laundry, and parking. Ideal for guests who love vibrant, walkable neighborhoods. We’re locals and happy to share our favorite hikes, wineries, and spots to explore!

Top guest favorite
A dining area features a wooden table surrounded by four chairs, complemented by a decorative rug. Exposed beams and ductwork enhance the industrial style. Natural light fills the space through large glass walls, revealing the adjacent kitchen and bedroom area.
Home in Downtown SLO
4.98 out of 5 average rating, 261 reviews

Mid Century Modern Loft Downtown SLO

This unique place has a style all it's own. Mid century modern loft located just a few blocks from downtown SLO. 10 min walk and 3 min drive to all the great shops and restaurants SLO has to offer. Thick glass walls in the bedroom allow for an open loft like experience. Many fun details throughout the place create a truly unique vibe. This 800sf loft located upstairs above a salon is private and has designed parking.

Top guest favorite
A contemporary home is highlighted with expansive glass doors, allowing views of the surrounding landscape. A wooden dining table is shown, adorned with a sunflower. The deck extends along the residence, featuring comfortable seating areas.
Home in San Luis Obispo
4.95 out of 5 average rating, 124 reviews

Sanctuary on Sunset Ridge ~ Panoramic Ocean Views

Enjoy extraordinary VIEWS, PEACE, and PRIVACY just 15 minutes from downtown and beaches. Within 10-15 minutes: Hiking, Biking, SUP, Kayaking, Surfing, Wine Tasting, Great Restaurants, etc., etc. We are good-dog friendly. 3-night minimum stay. We have 2 ensuite King bedrooms - the 2nd has a loft with a double bed. Check us out on Insta: @sanctuaryonsunsetridge

Top guest favorite
A covered outdoor patio offers stylish seating around a central fire pit, overlooking expansive views of rolling hills. A ceiling fan provides comfort, while soft light illuminates the landscape at sunset, creating a welcoming space for relaxation.
Home in Paso Robles
5 out of 5 average rating, 271 reviews

High Ridge Cottage, Paso Robles

Perched on a gorgeous hilltop with 365 degree views of Paso Robles wine country this incredibly stylish, custom and newly built home with a hot tub offers stunning views, countless amenities and is centrally located to all the epic Central Coast points of interest including wineries, Sensorio light field, breweries and Vina Robles amphitheater!

Popular amenities for San Luis Obispo house rentals

When is the best time to visit San Luis Obispo?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceG$46,006 GYDG$46,006 GYDG$46,215 GYDG$50,606 GYDG$47,888 GYDG$59,389 GYDG$56,462 GYDG$52,697 GYDG$48,306 GYDG$43,078 GYDG$46,842 GYDG$44,124 GYD
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Quick stats about house rentals in San Luis Obispo

  • Total vacation rentals

    Explore 180 vacation rentals in San Luis Obispo

  • Verified guest reviews

    Over 14,890 verified reviews to help you choose

  • Family-friendly vacation rentals

    120 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 60 rentals that welcome pets

  • Rentals with dedicated workspaces

    90 properties have a dedicated workspace

  • Wi-Fi availability

    180 of San Luis Obispo vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across San Luis Obispo rentals

  • 4.9 Average rating

    San Luis Obispo stays are highly rated by guests—averaging 4.9 out of 5!

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