
House vacation rentals in San Luis Obispo
Find and book unique houses on Airbnb
Quick stats about house rentals in San Luis Obispo

Total vacation rentals
Explore 190 vacation rentals in San Luis Obispo

Verified guest reviews
Over 16,510 verified reviews to help you choose

Family-friendly vacation rentals
120 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 60 rentals that welcome pets

Rentals with dedicated workspaces
90 properties have a dedicated workspace

Wi-Fi availability
180 of San Luis Obispo vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across San Luis Obispo rentals

4.9 Average rating
San Luis Obispo stays are highly rated by guests—averaging 4.9 out of 5!
Top-rated house rentals in San Luis Obispo
Guests agree: these houses are highly rated for location, cleanliness, and more.

1884 Elegant Home: Fire Pit, Tesla Tech, Near DT
Step into history at this charming 2-bedroom railroad house in downtown SLO. Enjoy its preserved heritage, from the 11-foot tall ceilings to the spacious kitchen. Sleep luxuriously on Purple mattresses in both bedrooms. Unwind next to the fire pit in the backyard. It's a short 7 min. stroll to downtown & next to 5 restaurants including Sally Lou's coffee shop & the train station. Experience SLO's charm like never before with this perfect location home. Send us a message to plan your trip!

NEW Cozy Private House -Near Cal Poly and DT SLO
Perfect getaway in San Luis Obispo in a brand new secondary house in the rear of a large lot, completely detached with its own yard and fenced off. You will be located within 1 mile of Cal Poly and Downtown SLO, tucked between two beautiful mountains, Bishops Peak and Madonna Mountain. Access to the rear of Madonna Mountain hiking is 1/8 mile walk up the street. Grocery stores and coffee shops within 1/3 of a mile away and beautiful beaches are within a 15 minute drive North or South.

Farmhouse located on San Luis Obispo Central Coast
Welcome to Farmhouse805! Our newly renovated 3 bedroom, 2 bath farmhouse is situated on a 20-acre working farm located on San Luis Obispo's Central Coast in the heart of Edna Valley Wine Country. The home has been in our family for over 100 years. It features 1 king bed, 2 queen bedrooms, 2 bathrooms plus a private office with a sleeper sofa. Once you are back from exploring San Luis Obispo & the Central Coast you can step outside and enjoy the ambiance of the brand-new backyard patio.

Cozy Studio Close to Downtown SLO
Cozy Studio is located in a quiet residential neighbor with secure off street parking. Whether you choose to relax in my comfortably furnished studio or enjoy the private outdoor patio, my home will provide a serene retreat. From the house, it is a ten minute walk to downtown. Home features smart tv with Netflix, Hulu, and Sling. It also features high-speed wifi and air conditioning. Please note that the bedroom is upstairs and the bathroom is downstairs . Home Stay Permit # 0235-2020

Downtown SLO Victorian+Sleeps 12+Walkable+Private
Charming & spacious early 1900's Victorian home in the heart of San Luis Obispo. Easy 1/2-mile stroll to downtown. This historic treasure has all the characteristics and quirks that make vintage homes so special. It is decorated in a fun and casual way and comfortably sleeps up to 12 guests. Fully stocked retro kitchen with a restored 1954 O'Keefe-Merritt stove. Perfectly set-up to accommodate a large group of friends or family for a memorable trip to the beautiful Central Coast!

Entire Hobby Farm, Surrounded by Vineyards
This place is magical. Seven private acres with 360 degree views are surrounded by vineyards which can be seen through most windows. On property, depending on the season, you will find apples, pears, peaches, cherries, figs, loquats, persimmons, pomegranates, pecans, chestnuts, and several grape varieties. The outdoor space includes a wrap-around covered patio, outdoor dining, multiple sitting areas, fire pits, swings, games, and outdoor cooking. It is truly one of a kind.

Gorgeous Hilltop Oasis with Pool and Expansive Views
Feel cares slip away in the serene saltwater pool set among ancient oaks and endless vistas. Enjoy one of Atascadero's most beautiful neighborhoods, sitting atop the Hills of the Central Coast. Morning strolls are a literal walk in the clouds with stunning canyon views and deer roaming nearby. It's hard to believe this property is only 8 minutes from the freeway. This comfortable tri-level four bedroom home is perfectly practical for family or group entertaining.

Serenity On Serrano
Serenity on Serrano is a Frank Lloyd Wright-inspired peaceful haven set in one of SLO's most prestigious neighborhoods right on the edge of a creek. This midcentury modern home is just steps to hiking, the downtown, shopping, and restaurants. Be prepared for nature as it's common to be greeted by wild turkeys, birds, and more. Enjoy the tranquility of minimalist design. Note: There is $25 per night for each extra guest over 4. Permit # H-0408-2023

Wine Country Hilltop Retreat
Kick back and relax in this calm, stylish space with spectacular Edna Valley views. Read a book on your hillside patio and see buffalo and longhorns grazing in neighboring fields. After an incredible sunset, unwind by your firepit at night under a sky full of stars. This private country escape is also at the center of it all - 15 minutes to beaches & Cal Poly, 5 minutes to airport & 20+ wineries/tasting rooms, 10 minutes to beautiful downtown SLO.

SLO Vibes
Enjoy a stylish experience at this centrally-located place with a contemporary design and panoramic hillside views. Modern all-electric home featuring 2 bedrooms and 2.5 bathrooms is ideally located just minutes from Downtown San Luis Obispo and Edna Valley Wine Country. Step into a modern kitchen, and private balcony off the heart of your living space. Both bedrooms have ensuite bathrooms. 2-car garage. Hope you soak in this vibrant home!

The Downtown House SLO with Private Parking
Charming 1920s bungalow in the heart of downtown San Luis Obispo! Walk to top restaurants, coffee shops, parks, and the famous Farmers Market. Perfect for SLO Marathon runners—just a mile from the starting line. Original details + modern upgrades, A/C, full kitchen, laundry, and parking. Ideal for guests who love vibrant, walkable neighborhoods. We’re locals and happy to share our favorite hikes, wineries, and spots to explore!

Mid Century Modern Loft Downtown SLO
This unique place has a style all it's own. Mid century modern loft located just a few blocks from downtown SLO. 10 min walk and 3 min drive to all the great shops and restaurants SLO has to offer. Thick glass walls in the bedroom allow for an open loft like experience. Many fun details throughout the place create a truly unique vibe. This 800sf loft located upstairs above a salon is private and has designed parking.
Popular amenities for San Luis Obispo house rentals
House rentals with a pool

PaSO PaNORAMA-Swimming Pool, Hot Tub, & Views

Campover Ranch in Paso Robles - Saltwater Pool

Spacious SLO CAL Home w/ Pool, Spa. Pet Friendly!

San Luis Obispo House With Pool And Hot Tub

Getaway at the Highlands+Heated Pool+Hot Tub

Luxury Mountain View Retreat Pool/jacuzzi

Seven Oaks Cottage

Historic 1895 Edna Railhouse with Heated Pool
Weekly house rentals

Mid-century home in the heart of Arroyo Grande.

STENNER CREEK RANCH

The Quailhouse on Ranch near Avila Beach

Olive House - tranquil retreat on an olive farm

Back Bay Getaway - Dog Friendly - Home in Los Osos

Spacious Slo Studio: AirBnB Dream

Spacious SLO Retreat | Walk to DT/Parks

Modern Cayucos Bungalow - Ocean Views and Hot Tub
Private house rentals

1 Block from Beach with long driveway for parking

Blue Wave of Avila

Downtown Craftsman with Courtyard

Upscale. Pet friendly. Great location! 6-10 guests

Boutique Bungalow, San Luis Obispo

Hillside view with hot tub too

2735 Nokomis

Cozy, Clean and Close to downtown SLO!
When is the best time to visit San Luis Obispo?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$47,465 GYD | G$46,420 GYD | G$43,701 GYD | G$50,602 GYD | G$47,883 GYD | G$59,384 GYD | G$56,456 GYD | G$52,693 GYD | G$48,302 GYD | G$48,720 GYD | G$51,647 GYD | G$46,211 GYD |
| Avg. temp | 12°C | 12°C | 13°C | 14°C | 15°C | 16°C | 18°C | 18°C | 18°C | 17°C | 14°C | 11°C |
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- Cayucos Beach
- Moonstone Beach
- Pismo State Beach
- Hearst Castle
- Morro Strand State Beach
- Montaña de Oro State Park
- Cayucos State Beach
- Los Padres National Forest
- Morro Rock Beach
- Morro Bay Golf Course
- California Polytechnic State University
- Mission San Luis Obispo de Tolosa
- Oceano Dunes State Vehicular Recreation Area
- Dinosaur Caves Park
- Sensorio
- Pismo Preserve
- Charles Paddock Zoo
- Monarch Butterfly Grove
- Vina Robles Amphitheatre
- JUSTIN Vineyards & Winery
- Tablas Creek Vineyard
- Downtown City Park
- Elephant Seal Vista Point
- Talley Vineyards
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