
House vacation rentals in San Luis Obispo
Find and book unique houses on Airbnb
Quick stats about house rentals in San Luis Obispo

Total vacation rentals
Explore 190 vacation rentals in San Luis Obispo

Verified guest reviews
Over 16,510 verified reviews to help you choose

Family-friendly vacation rentals
120 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 60 rentals that welcome pets

Rentals with dedicated workspaces
90 properties have a dedicated workspace

Wi-Fi availability
180 of San Luis Obispo vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across San Luis Obispo rentals

4.9 Average rating
San Luis Obispo stays are highly rated by guests—averaging 4.9 out of 5!
Top-rated house rentals in San Luis Obispo
Guests agree: these houses are highly rated for location, cleanliness, and more.

Ranch house with beautiful views
Private and gated ranch! Unique newly renovated ranch house with mountain views!Enter our 160-acre gated ranch and unwind as you wind down a well-maintained gravel road to your house! The house is 5 miles from downtown San Luis Obispo and 3.3 miles from Cal Poly SLO. Enjoy a spacious covered front porch and a large fully fenced backyard with a barbeque and dining furniture. The large backyard sits against a hillside for quiet privacy. You will see horses and cattle from each window in the home!!
LocationFamilyHiking

The Los Osos Valley Guest House
Settle into authentic 'SLO CAL' in our cozy and casual Surf Ranchita - The Los Osos Valley Guest House is a rustic hideaway nestled between quaint rural farmlands, laid back Los Osos and the rugged natural coastline. It's a perfect base stay with it's casual rustic vibe, unique character and renovated modern conveniences. Enjoy a fully stocked 3 bedroom house with hot tub, infrared sauna, outdoor shower, 4 TVs private WiFi, heated marble floors, BBQ patio and outdoor seating with amazing views.
LocationFamilyParks

Cozy Studio Close to Downtown SLO
Cozy Studio is located in a quiet residential neighbor with secure off street parking. Whether you choose to relax in my comfortably furnished studio or enjoy the private outdoor patio, my home will provide a serene retreat. From the house, it is a ten minute walk to downtown. Home features smart tv with Netflix, Hulu, and Sling. It also features high-speed wifi and air conditioning. Please note that the bedroom is upstairs and the bathroom is downstairs . Home Stay Permit # 0235-2020
LocationValueCheck-in

Boutique Bungalow San Luis Obispo
Go green in this immaculate low allergen mid-century modern 1000 sf bungalow. Solar electric power includes a 50A Tesla car charger while the yard features a low-water, Japanese bamboo design. Open full size kitchen, high end stainless appliances, spacious living room, cable TV, high speed wifi, 2 bed- 2 bath, master king bedroom with sleep number bed, full contemporary bath & second king bedroom. Laundry room, storage, bike shed, private courtyard, sunny patio with great view.
FamilyLocationLong stay

Upscale. Pet friendly. Great location! 6-10 guests
Welcome! This 4/2 fully upgraded, Spanish Med. in D/T SLO is filled with ambiance! Hotel-grade queen beds and furnishings suit up to 10 perfectly. Formal or gazebo dining, fire pit/BBQ, and games area. 2 car driveway parking. Easy self-entry. Complimentary drink on arrival! Clean quiet house trained pets Ok! 20 mins to beaches/wineries. Includes a detached bungalow/master suite with 1/2 bath. A quality spot for entertaining, or to relax in. You’ll LOVE it here~
ValueLocationOutdoor spaces

Cozy, Clean and Close to downtown SLO!
Relax in my comfortably furnished, air conditioned (a rare amenity in SLO), 3 bedroom home. Located in a quiet, residential neighborhood with secure, off-street parking. Multiple indoor and outdoor living spaces will provide a quiet retreat for everyone! My home features Air-conditioning, soft water, reverse osmosis drinking water, a record player with vinyl collection and games. WiFi, Sling TV, Netflix & Hulu! Business Lic # 113276. Home Stay Permit # 0235-2020
LocationValueNearby

Serenity On Serrano
Serenity on Serrano is a Frank Lloyd Wright-inspired peaceful haven set in one of SLO's most prestigious neighborhoods right on the edge of a creek. This midcentury modern home is just steps to hiking, the downtown, shopping, and restaurants. Be prepared for nature as it's common to be greeted by wild turkeys, birds, and more. Enjoy the tranquility of minimalist design. Note: There is $25 per night for each extra guest over 4. Permit # H-0408-2023
LocationFamilyComfort

Wine Country Hilltop Retreat
Kick back and relax in this calm, stylish space with spectacular Edna Valley views. Read a book on your hillside patio and see buffalo and longhorns grazing in neighboring fields. After an incredible sunset, unwind by your firepit at night under a sky full of stars. This private country escape is also at the center of it all - 15 minutes to beaches & Cal Poly, 5 minutes to airport & 20+ wineries/tasting rooms, 10 minutes to beautiful downtown SLO.
LocationFamilyBeach

SLO Vibes
Enjoy a stylish experience at this centrally-located place with a contemporary design and panoramic hillside views. Modern all-electric home featuring 2 bedrooms and 2.5 bathrooms is ideally located just minutes from Downtown San Luis Obispo and Edna Valley Wine Country. Step into a modern kitchen, and private balcony off the heart of your living space. Both bedrooms have ensuite bathrooms. 2-car garage. Hope you soak in this vibrant home!
FamilyLocationComfort

Cozy Retreat Walking Distance to Downtown
This historic home has been recently remodeled. It sits in a quiet, friendly neighborhood which is walking distance to downtown. The second bedroom overlooks a large, beautiful garden and you can hear the gentle song of frogs at night and church bells in the morning. All beds feature luxury linens and the Wifi is fantastic! Forget your worries in this spacious and serene space. Walking distance to High Street Deli and Village Host Pizza.
ValueLocationTV

The Downtown House SLO with Private Parking
Charming 1920s bungalow in the heart of downtown San Luis Obispo! Walk to top restaurants, coffee shops, parks, and the famous Farmers Market. Perfect for SLO Marathon runners—just a mile from the starting line. Original details + modern upgrades, A/C, full kitchen, laundry, and parking. Ideal for guests who love vibrant, walkable neighborhoods. We’re locals and happy to share our favorite hikes, wineries, and spots to explore!
FamilyValueCheck-in

Mid Century Modern Loft Downtown SLO
This unique place has a style all it's own. Mid century modern loft located just a few blocks from downtown SLO. 10 min walk and 3 min drive to all the great shops and restaurants SLO has to offer. Thick glass walls in the bedroom allow for an open loft like experience. Many fun details throughout the place create a truly unique vibe. This 800sf loft located upstairs above a salon is private and has designed parking.
ValueFamilyGetting around
Popular amenities for San Luis Obispo house rentals
House rentals with a pool

San Luis Obispo House With Pool And Hot Tub
LocationFamilyPets

Gorgeous Hilltop Oasis with Pool and Expansive Views
ValueFamilyGetting around

Getaway at the Oaks +Heated pool+hot tub
ValueFamilyShared spaces

Historic 1895 Edna Railhouse with Heated Pool
LocationFamilyParking

Spacious SLO CAL Home w/ Pool, Spa. Pet Friendly!
FamilyValueGrill

Seven Oaks Cottage
FamilyLocationWifi

PaSO PaNORAMA-Swimming Pool, Hot Tub, & Views
FamilyValueCondition

360 Degree Hilltop Vineyard Views in Wine Country
FamilyLocationGetting around
House rentals with a hot tub

Blue Wave of Avila
ValueFamilyLayout

Beach House ON Pismo Beach
FamilyValueGetting around

Bishops Peak Retreat-Spa, Family Friendly!
LocationValueBeach

Central Coast - Creekside Living
LocationFamilyGetting around

4.5 Acre Farmhouse in Wine Country w/Hot Tub
ValueFamilyQuiet

New Spanish Home in Downtown Avila Beach
FamilyValueLaundry

Pelican Cove Vacation Rental at the Back Bay
ValueFamilyLayout

High Ridge Cottage - vineyard views and hot tub
FamilyLocationQuiet
House rentals with free parking

OMG Playground, close to Beach, Family Fun
FamilyLocationIndoor spaces

STENNER CREEK RANCH
ValueLocationHospitality

Spacious SLO Retreat | Walk to DT/Parks
LocationFamilyLong stay

Farmhouse located on San Luis Obispo Central Coast
FamilyLocationAccuracy

The Cottage on Palm
ValueFamilyBathroom

Private, Wooded Home, and a Modern Design
LocationFamilySleep quality

Largest Ocean View
ValueLocationParks

Stargazing Studio with Private Deck
ValueFamilyKitchen
When is the best time to visit San Luis Obispo?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$47,392 GYD | G$46,348 GYD | G$43,634 GYD | G$49,271 GYD | G$51,150 GYD | G$60,545 GYD | G$56,369 GYD | G$52,611 GYD | G$48,227 GYD | G$48,644 GYD | G$51,567 GYD | G$46,139 GYD |
| Avg. temp | 12°C | 12°C | 13°C | 14°C | 15°C | 16°C | 18°C | 18°C | 18°C | 17°C | 14°C | 11°C |
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