Guesthouse vacation rentals in San Luis Obispo

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Quick stats about guesthouse rentals in San Luis Obispo

  • Total vacation rentals

    Explore 30 vacation rentals in San Luis Obispo

  • Nightly prices starting at

    San Luis Obispo vacation rentals start at G$14,645 GYD per night before taxes and fees

  • Verified guest reviews

    Over 5,600 verified reviews to help you choose

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wi-Fi availability

    30 of San Luis Obispo vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across San Luis Obispo rentals

  • 4.9 Average rating

    San Luis Obispo stays are highly rated by guests—averaging 4.9 out of 5!

Top-rated guesthouse rentals in San Luis Obispo

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Top guest favorite
A charming garden area is framed by brick pathways, with a wooden table and chairs positioned nearby. Lush greenery and various plants create a serene outdoor atmosphere, while a wooden gate provides privacy and access to the space. The ground appears damp, suggesting recent rain.
Guesthouse in San Luis Obispo
4.97 out of 5 average rating, 698 reviews

SLO Guesthouse - quiet - near downtown - #115545

Private studio with it's own entrance located in lovely SLO. Includes a queen size Murphy bed (people rave about the comfort of this bed), 3 piece bathroom, table & two chairs, desk, closet, TV, WiFi & kitchenette. Coffee, tea with fixings are provided. 4 blocks from the downtown cultural-hub, hip restaurants, Farmer's Market, the Historic Mission and more. The Edna Valley wine country is 5 minutes away and the Beach is 10 minutes away. The Perfect Location to come experience the "SLO Life"!

LocationFamilyNearby

Guest favorite
Guesthouse in San Luis Obispo
4.93 out of 5 average rating, 1074 reviews

Modern Private Cottage+walkable+views+patio w/ BBQ

This adorable cottage is located 1 mile from downtown SLO and is equidistant to local wineries! Clean and tastefully decorated- equip with a full kitchen, comfortable sleeping accommodations and all the modern luxuries of home. This private studio is nestled on the backside of a beautifully landscaped property with a separate entrance and secluded patio area distanced from the main home offering you peace and serenity. Just a short stroll to Taste, SLO Co-Op, Del Monte's, Sally Loo's & many more

ValueLocationSolo travel

Guest favorite
A charming guest house nestled among lush greenery features a covered front porch with colorful chairs. A stone wall surrounds the property, complemented by vibrant plants and cacti, offering a serene and welcoming entrance.
Guesthouse in San Luis Obispo
4.95 out of 5 average rating, 696 reviews

Pacific Coast Hwy Bunkhouse in San Luis Obispo

Rock Bottom Ranch is conveniently located half way between Los Angeles and San Francisco right off of Pacific Coast Hwy 1. It is an easy 7 minutes to San Luis Obispo's Cal Poly. The most beautiful beaches in Morro Bay area 3 miles away. The location is perfect. You will come through a private gate and nature will surround you with its beauty and serenity. Here you may see the wild turkey showcasing his feathers in his mating ritual or several deer grazing on the grass in the nearby field.

LocationFamilyLaundry

Top guest favorite
The guesthouse is framed by blooming trees and colorful flowers, set amidst natural landscaping. A pathway leads to the entrance, with a soft blue sky and gentle hills visible in the background, creating a harmonious connection with the surroundings.
Guesthouse in Arroyo Grande
5.0 out of 5 average rating, 186 reviews

Central Coast Country Retreat

My husband Mike and I are artists. We searched for 10 years to find the perfect spot for our retirement years. We found 7 1/2 acres here, on the Central Coast, with spectacular views of verdant trees covering rolling hills that reach all the way to the distant mountains south and east of Arroyo Grande Village. Come and stay in our Guesthouse, relax, explore the property, walk the quiet country lanes. For a rural setting, we are surprisingly close to all amenities, beaches, and wineries.

LocationFamilyLaundry

Top guest favorite
A light-filled studio is presented with a spacious bed, blue cabinetry, and a full kitchen that includes a microwave and stove. A small dining table with black chairs is positioned near the windows, providing a view of the room's warm wooden flooring.
Guesthouse in Downtown SLO
4.97 out of 5 average rating, 633 reviews

Downtown Historic District Sunset Studio

Enjoy a hotel quality stay, professionally cleaned prior to each guest, located in the beautiful downtown historic district. Studio is equipped to provide you with everything you need for an enjoyable stay; including washer/dryer, AC/ Heat. From the deck enjoy magnificent sunset views framed by San Luis Mountain and Bishop's Peak while enjoying dining al fresco. We are 4 walkable blocks to downtown and a mile to Cal Poly. The beach is about a 10 min drive away. You can't beat the location!

ValueFamilyCondition

Top guest favorite
A modern kitchen features stylish white cabinetry and a mosaic tile backsplash. Stainless steel appliances include a stove and refrigerator. An island provides additional seating with four high-backed chairs. A workspace with a chair is conveniently situated near the kitchen counter.
Guesthouse in Arroyo Grande
4.99 out of 5 average rating, 316 reviews

Harrison's Hide Away

Come stay, come play, come work. Stylish modern one bedroom flat w/ comfy king size bed and queen-size sofa sleeper. Light, bright living space, lots of windows and very spacious . Our guest house is in the heart of Arroyo Grande and next door to everything. So if you are on a family vacation, business trip or couples retreat; experience the central coast, relax in a beautiful home, enjoy outdoor patio, with w/ fire-pit and barbecue for outdoor fun. Simple & Upscale (845 Sq Ft)

LocationFamilyParks

Top guest favorite
A cozy studio space features a queen-size bed with navy bedding and a decorative pillow. The kitchen area is visible, equipped with modern appliances. Soft lighting from bedside lamps enhances the welcoming ambiance. A piece of artwork depicting coastal scenery is displayed above the bed.
Guesthouse in Baywood-Los Osos
5.0 out of 5 average rating, 292 reviews

Retreat Studio with Patio and Full Kitchen

This retreat studio features a private patio space with lots of things to do and explore close by. It’s located 1 mile from Baywood Park. 8 miles from Montaña de Oro State Park-ample hiking and walking options against a beautiful backdrop of the Pacific Ocean and Eucalyptus trees. 10 minute drive to Morro Bay, the ocean and you can see seals and otters. 15 minute drive to San Luis Obispo. 25 minute drive to Edna Valley or 45 mins north to Paso Robles vineyards and wine tasting.

LocationValueHeating

Top guest favorite
A welcoming entrance is framed by lush green foliage and vibrant purple flowers. A rustic wooden sign reading 'Welcome' adorns the fence, complemented by a small mat leading to the entrance. Soft sunlight filters through the leaves, creating a serene atmosphere.
Guesthouse in Downtown SLO
4.98 out of 5 average rating, 697 reviews

Cottage in SLO / Historic Downtown District

“Cottage in SLO” is located in the historic district of San Luis Obispo with its century old homes and buildings. Enjoy the three block walk to downtown with all its amenities: Restaurants to please every pallet, from BBQ to gourmet. Coffee shops, theaters, galleries, and the world famous Farmers Market event every Thursday night. Bike paths are on the same street that will take you anywhere in SLO and beyond. . (Bikes provided) Perfect for two. Homestay permit # -0606-2019

LocationFamilyCheck-in

Top guest favorite
An outdoor patio area features a neatly arranged pattern of tiles and artificial grass, bordered by vibrant greenery and flowering plants. A small tree provides shade, and large glass doors lead to the interior studio space, enhancing the connection between indoor and outdoor areas.
Guesthouse in San Luis Obispo
4.97 out of 5 average rating, 118 reviews

Guesthouse Studio

Walking distance to downtown and also to Cal Poly, this studio is located behind the primary residence, with French doors that open onto a large tile patio. The 400 sq. ft. space is perfect for 2 people but can accommodate up to 4. The first bed is situated in a semi-private corner of the studio, while the second bed rolls out into the sitting room. The kitchen is equipped for simple meal prep with a microwave/convection oven and portable induction cooktop.

FamilyValueComfort

Top guest favorite
A comfortable sleeping area features a queen bed with crisp white linens and gray-striped accent pillows. Next to the bed, a dark nightstand displays a decorative lamp and a collection of books. A closet with sliding doors is visible beside the bed.
Guesthouse in Pismo Beach
4.98 out of 5 average rating, 633 reviews

Shell Beach Hideaway

Welcome to picturesque Shell Beach Hideaway. This charming studio cottage offers privacy and seclusion, yet walking distance to restaurants, cafes, a private small beach, and to numerous points of interest This is a NO SMOKING cottage.This private studio is located behind our home in a quiet neighborhood with a full bath, queen bed, wifi, and a full kitchen. No pets allowed. Maximum guest two (2). Not suitable for children. License 19951

LocationFamilyIndoor spaces

Top guest favorite
A bright living area features large windows allowing natural light to illuminate the space. A comfortable gray sofa is paired with two stylish chairs. An artistic rug and a unique wooden coffee table enhance the inviting atmosphere, while a tall plant adds a touch of greenery.
Guesthouse in Atascadero
4.98 out of 5 average rating, 420 reviews

Atascadero Guesthouse Central Coast Wine Country

This light and airy hideaway was designed and built by the host incorporating her own handiwork in art and furnishings. Initially a granny flat, it's been transformed into a comfortable and spacious hang out. Its central location makes it ideal to explore the area. The twin beds can be easily configured to a king bed. Price includes a 13% local tax. We are on gated 3 acres. The pool sits between the guest house and our house.

LocationFamilyNearby

Guest favorite
A covered patio area is revealed, featuring a wooden ceiling with exposed beams. Wicker chairs surround a glass table, and a barbeque is positioned nearby. Lush greenery and neatly trimmed hedges create a peaceful backdrop, enhancing the outdoor living space.
Guesthouse in San Luis Obispo
4.95 out of 5 average rating, 292 reviews

Wine Country Casita

Our charming guest home is located in the heart of the Edna Valley. We are minutes to downtown San Luis Obispo and Pismo Beach, steps away from award winning wineries. Romantic and restful with easy access to all the central coast has to offer. Cal Poly University is 7 miles from the Casita. We are less than 2 miles from two wedding venues. Green Gate and the White Barn.

FamilyValueTV

Popular amenities for San Luis Obispo guesthouse rentals

When is the best time to visit San Luis Obispo?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceG$31,800 GYDG$32,428 GYDG$29,917 GYDG$38,913 GYDG$39,332 GYDG$42,051 GYDG$35,147 GYDG$31,591 GYDG$31,591 GYDG$34,520 GYDG$34,520 GYDG$34,311 GYD
Avg. temp12°C12°C13°C14°C15°C16°C18°C18°C18°C17°C14°C11°C

Destinations to explore