Guesthouse vacation rentals in San Luis Obispo

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Top-rated guesthouse rentals in San Luis Obispo

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Guest favorite

Guesthouse in San Luis Obispo

4.97 out of 5 average rating, 477 reviews

SLO Guesthouse - quiet - near downtown - #115545

Private studio with it's own entrance located in lovely SLO. Includes a queen size Murphy bed (people rave about the comfort of this bed), 3 piece bathroom, table & two chairs, desk, closet, TV, WiFi & kitchenette. Coffee, tea with fixings are provided. 4 blocks from the downtown cultural-hub, hip restaurants, Farmer's Market, the Historic Mission and more. The Edna Valley wine country is 5 minutes away and the Beach is 10 minutes away. The Perfect Location to come experience the "SLO Life"!

Oct 14 – 21

G$22,647 GYD per night

Guest favorite

Guesthouse in Atascadero

4.98 out of 5 average rating, 121 reviews

Olive Branch guest house close to the lake

Cute and cozy 800 sq ft guest house on the property of one of the original colony homes! Just a half mile to Atascadero Lake and under two miles to downtown Atascadero. Only a 20 min drive west to Morro Bay, south to SLO and north to Paso. Close to hwy 101 for easy access. An elementary school sits across the street so you may hear an occasional bell. Plenty of natural light with french doors that open to the private patio. Downstairs there is room for lounging, watching movies and dining.

Aug 7 – 14

G$23,816 GYD per night

Guest favorite

Guesthouse in Baywood-Los Osos

4.94 out of 5 average rating, 374 reviews

Charming backyard cottage, quiet and private

We have a charming backyard cottage available that is walking distance to Baywood, Sweet Springs Preserve, Elfin Forest, and restaurants nearby. The cottage has it's own entrance. The kitchenette is stocked with all the essentials to make a meal. There is a full sized bed in the bedroom and a queen size futon in the living room. The french doors of the bedroom open to a private patio that is shaded by an African conifer. Please note, the cottage is not suitable for kids under 10 years old.

Jul 14 – 21

G$25,437 GYD per night

Guest favorite

Guesthouse in Arroyo Grande

4.94 out of 5 average rating, 510 reviews

Private, serene studio near beach & wineries

Our private country setting offers you a tranquil spot to unwind and discover the beauty of the Central Coast. Ideally located on a quiet country street, you are a short drive from (under 10 minutes) dipping your toes in the ocean at Pismo Beach, sipping award-winning wine at one of the dozens of nearby Edna Valley wineries or getting a bite to eat at many of the casual or finer dining restaurants. When you arrive, our dog and our other pets large and small will give you a warm welcome!

Oct 28 – Nov 4

G$26,231 GYD per night

Guest favorite

Guesthouse in Morro Bay

4.94 out of 5 average rating, 125 reviews

Renovated Private Hippy Beach Shack With Full Bath

Enjoy all that Morro Bay has to offer from this recently renovated eco-friendly live/work space featuring everything needed for a quiet retreat by the beach. Enjoy the cool, foggy mornings listening to the seagulls and foghorn with a cup of Peet's Coffee in the private courtyard, or cozy up with a book in bed and listen to the ocean waves at night. Find peace to complete your work from the decked-out office area. Whatever your Morro experience is, enjoy it at The Shack! License #16312467

May 9 – 16

G$24,016 GYD per night

Guest favorite

Guesthouse in San Luis Obispo

4.98 out of 5 average rating, 524 reviews

Cottage in SLO / Historic Downtown District

“Cottage in SLO” is located in the historic district of San Luis Obispo with its century old homes and buildings. Enjoy the three block walk to downtown with all its amenities: Restaurants to please every pallet, from BBQ to gourmet. Coffee shops, theaters, galleries, and the world famous Farmers Market event every Thursday night. Bike paths are on the same street that will take you anywhere in SLO and beyond. . (Bikes provided) Perfect for two. Homestay permit # -0606-2019

Sep 1 – 8

G$45,348 GYD per night

Guest favorite

Guesthouse in San Luis Obispo

4.92 out of 5 average rating, 291 reviews

The tree house

Peaceful, bright and airy 450 sq foot unit. Just over a mile from downtown and 2.1 miles from Cal Poly. The unit is totally separate and set away from the main house with a private entrance and private outdoor seating area. Enjoy a restful sleep in a king sized bed with down comforter and pillows and Italian cotton sheets. Stylish bathroom with large shower and vanity. Separate living room/kitchenette area with coffee & tea making facilities, a breakfast bar and bar seating.

Sep 15 – 22

G$32,713 GYD per night

Guest favorite

Guesthouse in Baywood-Los Osos

4.87 out of 5 average rating, 295 reviews

Beautiful Views and Unforgettable Beaches Await!

Rustic private studio on a former Orchid farm in the quaint town of Los Osos. Walk or bike ride to the bay or the beach. Drive 5 minutes to Montana De Oro State Park which hosts breathtaking landscapes, over 100 different biking and hiking trails and incredibly pristine beaches. Morro Bay is just around the corner with kayaking, surfing and seafood galore. Enjoy nightlife, restaurants and shops just 15 minutes away in San Luis Obispo. Come enjoy this Central Coast paradise!

Apr 7 – 14

G$27,541 GYD per night

Guest favorite

Guesthouse in Atascadero

4.92 out of 5 average rating, 193 reviews

Historic 1919 carriage house

The J Birdsall Banker property was developed from 1917 to 1919. The carriage house was constructed in 1919 and converted into housing during the housing shortage of World War 11 We have always referred to it as the honey moon suite because so many couples have lived there over the last 65 years. Couples still sometimes still stop to look and share old memories The carriage house was recently upgraded with all new interiors and is comfortably furnished

Jan 12 – 19

G$26,576 GYD per night

Guest favorite

Guesthouse in Santa Maria

4.99 out of 5 average rating, 1444 reviews

French Country Casita - Breakfast Included

This stand-alone casita sits in the privacy of our rear yard and has a separate entrance. We are three minutes from highway 101 in the newer La Ventana community. Surrounded by beautiful mountain views on the Central Coast and close to many flourishing wineries, this residence is 20 minutes south of Pismo Beach, 30 minutes from San Luis Obispo, one hour north of Santa Barbara, close to the beautiful Danish city of Solvang and Santa Ynez.

Oct 15 – 22

G$22,977 GYD per night

Guest favorite

Guesthouse in San Luis Obispo

4.94 out of 5 average rating, 922 reviews

Modern Private Cottage- 1 mile to downtown SLO

This adorable cottage is located 1 mile from downtown SLO and is equidistant to local wineries! Clean and tastefully decorated- equip with a full kitchen, comfortable sleeping accommodations and all the modern luxuries of home. This private studio is nestled on the backside of a beautifully landscaped property with a separate entrance and secluded patio area distanced from the main home offering you peace and serenity.

Dec 5 – 12

G$36,649 GYD per night

Guest favorite

Guesthouse in San Luis Obispo

4.92 out of 5 average rating, 122 reviews

SLO Casita, a short walk to everything!

Visit our sweet casita at the foot of Cerro San Luis mountain in San Luis Obispo! This cozy little spot is around the corner from an incredible deli, a short walk to a beautiful hike, and a 15 -20 minute walk to downtown. This is an ideal spot for a couple looking to soak up the best San Luis has to offer or a group of up to three to stay in the perfect location.

Oct 5 – 12

G$23,042 GYD per night