
House vacation rentals in San Luis
Find and book unique houses on Airbnb
Quick stats about house rentals in San Luis

Total vacation rentals
Explore 120 vacation rentals in San Luis

Nightly prices starting at
San Luis vacation rentals start at G$4,184 GYD per night before taxes and fees

Verified guest reviews
Over 3,340 verified reviews to help you choose

Family-friendly vacation rentals
110 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 40 rentals that welcome pets

Vacation rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
40 properties have a dedicated workspace

Wi-Fi availability
120 of San Luis vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across San Luis rentals

4.9 Average rating
San Luis stays are highly rated by guests—averaging 4.9 out of 5!
Top-rated house rentals in San Luis
Guests agree: these houses are highly rated for location, cleanliness, and more.

Luxury" Home" 5 minutes from the border sleeps 6
This luxury home is designed thinking of our guest experience, cozy and comfortable . You will enjoy the indoor and outdoor areas great for a couples getaway asome for family time and lovely for having the house for yourself. Enjoy yourselves it’s an open layout well designed with unique charm a full kitchen super comfortable couch for movie night. outdoor is the perfect space to have a drink and relax its your home away from home Two private airbnbs with private entrance and private back yards
4.96 out of 5 average rating, 55 reviews
Yuma’s Best | Pet Friendly | Snowbirds Welcome
Modern desert retreat in the clean, quiet Lynwood neighborhood of Yuma. Open layout with high ceilings and dome skylights that bring in natural light without added desert heat. Ideal for snowbirds, families, traveling professionals, and guests visiting Algodones for dental care (18 mins). Pet-friendly with private backyard patio—perfect for relaxing mornings and evening grilling. High-speed reliable WiFi, Spectrum cable TV + streaming. Close to shopping, golf, dunes, and Los Algodones, MX.
4.95 out of 5 average rating, 136 reviews
The Dandy House: A Stunning 3-Bedroom Charmer
This property is an extension of our local boutique in Yuma, Dandy Home and Ranch. Enjoy a stylish and cozy stay, as Dandy invites you to experience hospitality and inspiration, whether you are traveling for work or for pleasure. We are located just down the street from the hospital, and we are just steps away from Starbucks, and other convenient amenities. We invite you to relax in the backyard by the fire pit, cook an amazing meal, or cozy up by the fireplace, all in Dandy style.
4.99 out of 5 average rating, 134 reviews
San Luis,Arizona- Centrally located-7min to border
Casa Arizona is located in the heart of San luis Az, easy access to everything from this centrally located place. Less than 7 min from the San Luis Rio Colorado border. 25 min from Yuma. Our place is perfect to host comfortably up to 5 people. Washer and Dryer for your convenience. Short and long stays are welcome. Note: You are renting the main house. We also have an studio on the property with its own private entrance and patio. Both spaces are designed for a relaxing experience.
4.94 out of 5 average rating, 52 reviews
Newly Remodeled Home In The Heart Of Somerton
This newly remodeled home features three bedrooms and 2 full bathrooms. New flooring has been installed throughout the entire house The new kitchen includes pots and pans for you to enjoy a home cooked meal if you so desire. This cozy home located in the downtown/entertainment district of "the best little city in Arizona" has a living room equipped with a smart tv and wi-fi internet in the entire home. Dining and entertainment is within walking distance of this beautiful home.
4.83 out of 5 average rating, 139 reviews
Large beautiful 3 bedroom pool home
Located in a beautiful and quiet subdivision this home boasts a large floor plan with plenty of room for a group of 10 and a sparkling pool. We’ve put a lot of thought into your stay with amenities like cold drinking water, a BBQ and washer and dryer to help you enjoy your stay, relax and unwind. Throw in a bath bomb (provided) and enjoy a soak in the tub or lay out pool side with a glass of wine. Master holds a king bed, 2nd room a queen, and 2 bunks with trundles in the 3rd.
4.84 out of 5 average rating, 128 reviews
Tuscany Style Casita
Discover a newly remodeled Tuscany-style casita that feels like a quiet Italian escape in the heart of Yuma. Thoughtfully furnished for up to four guests. This two bedroom casita is truly cozy and warm. The neighborhood is safe, quiet and well kept. We are centrally located with Onvida hospital 5 min away, 10 min to the airport, 10 min to Yuma Palms and downtown and just minutes from Sprouts, Starbucks, Bubba's 33, local restaurants and more. We offer gated private parking.
4.98 out of 5 average rating, 255 reviews
Relax & Unwind by the Fire Pit 3BR/2BA
Welcome to our cozy home! Enjoy this incredible clean and modern home. This home is ready for cooking, sleeping and enjoying the amazing Yuma sunshine. Our nearest shopping center is 2 miles away! We have a Walmart, Albertsons, Taco Bell…The marine base is 4 miles, the border of Algodones is 20 minutes drive. Locate in a safe and family neighborhood. Home is equipped with a fully accessible closet to ensure confort for longer stay.Just 4 miles to downtown Yuma and Hwy 8!
4.93 out of 5 average rating, 131 reviews
Casa Victoria | Comfort, location and privacy
Enjoy comfort, privacy, and a prime central location at Casa Victoria. A modern 2-story home (2 years old), perfect for families, couples, travelers, and pets. Sleeps up to 6 guests in a quiet, safe neighborhood—ideal for relaxing or exploring the city. Amenities: 🏡 2-story private home 🛏️Sleeps 6 guests 🚗 Covered parking for 2 cars 🔥 Gas BBQ grill ☕ Coffee station 🌅 Balcony 🐾 Pet-friendly 📍 Central location 🔒 Safe & peaceful area
4.98 out of 5 average rating, 124 reviews
Private Pool Retreat | 3BR Home Sleeps 8 | Firepit
Welcome to your perfect getaway! This stunning 3-bedroom, 2-bathroom home features a beautiful private pool, ideal for families and friends looking to relax and unwind. Nestled in a peaceful neighborhood, our home combines comfort and convenience, making it the perfect base for your vacation. Outdoor propane grill available for guest use. Propane is not provided; guests are responsible for refilling/exchanging the tank if needed
4.79 out of 5 average rating, 116 reviews
LUXURY Living!
You will enjoy your stay at this fully furnished LUXURY rental. It has 4 bedrooms, 2 bathrooms and is located on a quiet cul-de-sac. Relax on the large covered patio, next to the pool, or by fire pit. Great location in the center of town near the hospital, golf courses, shopping, and restaurants. You are just a short drive away from Mexico, Colorado River, sand dunes, and hiking.
4.94 out of 5 average rating, 413 reviews
House 2 bedrooms with/swimming pool
Enjoy your stay at "My Saguaro Casita" Has a beautiful pool, new air conditioning unit, a very comfortable home centrally located in Yuma, near the free way and close to Algodones and shopping centers. It offers you Outside and Inside options for entertainment with family and friends. Come and enjoy our home away from home.
4.91 out of 5 average rating, 218 reviewsPopular amenities for San Luis house rentals
House rentals with a pool

SunshineManor Heart of Yuma Heated Pool option
4.73 out of 5 average rating, 262 reviews
Yuma Cozy Casita
4.82 out of 5 average rating, 193 reviews
Casa Bonita
5.0 out of 5 average rating, 65 reviews
Green Relaxing Minimalist Home
5.0 out of 5 average rating, 71 reviews
Casa Vita
4.83 out of 5 average rating, 83 reviews
Casa Blanca
4.95 out of 5 average rating, 92 reviews
Palm Paradise —Private Pool, Outdoor Kitchen&Grill
4.96 out of 5 average rating, 28 reviews
Little Sedona in San Luis 3 Bedrooms Pool & Grill
4.87 out of 5 average rating, 53 reviewsWeekly house rentals

Retro vacation house.
4.88 out of 5 average rating, 60 reviews
"La casita" Cozy home away from home
4.92 out of 5 average rating, 37 reviews
Blue house
5.0 out of 5 average rating, 14 reviews
Family Home
4.96 out of 5 average rating, 23 reviews
House Hs excellent location
4.87 out of 5 average rating, 55 reviews
Casa Topaz, ideal for your stay, comfortable, safe
4.89 out of 5 average rating, 37 reviews
Casa Libertad -WiFi/AC/TV/Washing Machine/Dryer/Garage
4.98 out of 5 average rating, 40 reviews
Yuma Valley Casa
4.99 out of 5 average rating, 67 reviewsPrivate house rentals

Desert Escape-Minutes From MX Border
4.77 out of 5 average rating, 13 reviews
Camelias Apartment #2
4.96 out of 5 average rating, 67 reviews
Entire Home In Yuma Arizona
4.96 out of 5 average rating, 24 reviews
House with covered garage/barbecue
4.96 out of 5 average rating, 23 reviews
Luxury Modern Farmhouse w/ Theater & Chefs Kitchen
4.95 out of 5 average rating, 19 reviews
Centrally Located 4 Bedroom Home 2 Bathroom
4.96 out of 5 average rating, 45 reviews
Casa OMMA
5.0 out of 5 average rating, 25 reviews
Pet-Friendly 3BR Near Hospital + Private Yard
5.0 out of 5 average rating, 15 reviewsWhen is the best time to visit San Luis?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$21,968 GYD | G$23,642 GYD | G$23,014 GYD | G$22,805 GYD | G$21,550 GYD | G$20,922 GYD | G$21,131 GYD | G$21,340 GYD | G$20,922 GYD | G$19,039 GYD | G$20,922 GYD | G$21,550 GYD |
| Avg. temp | 13°C | 15°C | 18°C | 21°C | 25°C | 30°C | 34°C | 34°C | 30°C | 24°C | 17°C | 12°C |
Destinations to explore
- San Diego Vacation rentals
- Los Angeles Vacation rentals
- Phoenix Vacation rentals
- Las Vegas Vacation rentals
- Paradise Vacation rentals
- Scottsdale Vacation rentals
- Sedona Vacation rentals
- Big Bear Lake Vacation rentals
- Palm Springs Vacation rentals
- Joshua Tree Vacation rentals
- Tijuana Vacation rentals
- Tucson Vacation rentals





