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Vacation rentals in De Soto

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Top-rated vacation rentals in De Soto

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Top guest favorite
The cabin's welcoming entrance features a wooden porch supported by sturdy beams. Two rocking chairs sit on the porch, surrounded by greenery and stone accents. A red door and a large window enhance the cabin's rustic charm, while the natural setting invites relaxation.
Cabin in Cobden
4.99 out of 5 average rating, 156 reviews

Pop’s Country Cabin

Pop’s Country Cabin is a small remote cabin that sits 1/2mile off the road above a 5 acre lake on 77 acres of private land. The view from the front porch is amazing! You can sit, unwind, and watch the wildlife with a distant view of Bald Knob Cross. The cabin sits in the heart of Shawnee National Forrest and the Southern IL wine trail. You can enjoy the fire pit while watching the stars, with no distractions from neighbors, traffic, or lights. You can enjoy catch & release fishing from the bank

Top guest favorite
The exterior of a charming cottage features a welcoming entrance with a light-colored door. Two blue chairs and a small table are positioned on a stone path, surrounded by well-maintained grass and flower pots. In the background, horses can be seen grazing in a fenced pasture.
Guesthouse in Carbondale
5 out of 5 average rating, 277 reviews

Homestead Cottage

Enjoy tiny farmhouse life in this adorable 375 sq. foot cottage. Loaded with everything you need this little cottage is nestled privately behind some trees on our 11 acre farm. You will soon forget how close you are to town with the beautiful view from your windows and the pasture fence just steps out the back door. Whether you’re here for the wineries, amazing hiking, an SIU event (3 miles) or to visit with family, the Homestead Cottage will provide a comfortable retreat from any adventure.

Guest favorite
The spacious interior features a wood-beamed ceiling with natural light streaming through large windows. A comfortable leather sofa is positioned next to a sleek kitchen with modern appliances, while a dining counter with bar stools offers additional seating.
Tiny home in Marion
4.96 out of 5 average rating, 195 reviews

Upscale Cabin w/ Beach Near Lake of Egypt

The Purple Door Cabin – Luxury Pondside Retreat, Southern Illinois Unwind in this bright and luxurious 650-sq-ft studio cabin featuring vaulted wood ceilings, a modern kitchen, full bathroom with washer/dryer, and cozy living space with Smart TV. Step onto the covered deck to enjoy peaceful pond views or stroll to your private beach for swimming, paddle boarding, or fishing. End the evening around your fire pit — we provide the firewood — and experience the best of Lake of Egypt relaxation.

Top guest favorite
A comfortable living area features a stone fireplace beneath a mounted television. A wooden coffee table is surrounded by a brown leather sofa and a chair. Scenic wall art is displayed above the sofa, while natural light enters through a nearby window.
Cabin in Makanda
4.99 out of 5 average rating, 160 reviews

Hygge Log Cabin: HotTub & Hiking

Hi, hello, welcome! We are excited to have the opportunity to host you for your relaxing trip or jam packed adventure. Our local area has many hiking opportunities to explore, the Southern Illinois Wine Trail surrounds us, and the back roads have country views that are breathtaking. Our cabin will be waiting for your arrival or return, well equipped with a 55" TV above the gas fireplace, a comfortable King size bed, and an amazing back porch with a Weber Grill and huge hot tub.

Guest favorite
A rustic cabin stands elevated on a wooden deck with stairs leading up to it. The exterior is painted in a calming green hue, featuring a cozy seating area with a small table and chairs. Surrounding greenery provides a natural setting.
Treehouse in Goreville
4.95 out of 5 average rating, 176 reviews

Fun Treehouse Getaway • Firepit • Lake Access

Jaybird Treehouse Adventure | Lake of Egypt Perched among an oak tree and two tall pines, Jaybird Treehouse is a whimsical and welcoming retreat at Lake of Egypt in Goreville, IL. Designed for fun, peace, and togetherness, this pet-friendly treetop getaway offers comfort, charm, and just the right amount of adventure. With deer wandering through the yard, sunsets lighting up the sky, and stars sparkling overhead at night, your stay here is nothing short of magical.

Top guest favorite
The exterior of the cabin is surrounded by tall trees displaying vibrant autumn foliage. A porch extends from the front, offering a view of the yard blanketed in fallen leaves. Sunlight filters through the branches, enhancing the serene woodland setting.
Place to stay in Makanda
4.95 out of 5 average rating, 281 reviews

Secluded Cabin*Blue Sky & Shawnee*Pet-Friendly

Secluded, yet convenient. Within 5 min of two wineries, ziplining, trail heads, & I-57. Your unforgettable romantic wine country retreat or comfortable rest after hiking or travel. No TV or Wi-Fi (good cell signal though) but that is not why you’re here! Explore the vineyards, walk the trails, and drink complementary on-farm roasted coffee! Pets welcome when you add them to the reservation. We have them too! Maple Ridge Cabin : Gateway to Shawnee Wine Country

Top guest favorite
The treehouse is elevated on wooden stilts, surrounded by lush greenery. A wooden deck with a railing extends from the entrance, creating a welcoming outdoor space. Large windows brighten the upper level, while a sun art piece adorns the side of the structure.
Treehouse in Makanda
4.96 out of 5 average rating, 403 reviews

Panthers Inn Treehouse

Come nestle amongst the leaves at Panthers Inn Treehouse. This secluded, well equipped, elevated cabin has the perfect combination of natural beauty and artful luxury. Isolated yet conveniently located 2 minutes from Blue Sky and Feather Hill wineries, within 5 minutes of Panthers Den hiking trail and the Shawnee Hills canopy tour and only 10 min from I-57 exit 40. Panthers Inn is the perfect starting and ending point to your Shawnee Hills Wine Country vacation!

Guest favorite
A cozy living area is furnished with a large sectional sofa and a matching armchair, complemented by decorative cushions. Light filters through window blinds, and a soft area rug covers the hardwood floor. A small table is positioned nearby.
Home in Carbondale
4.86 out of 5 average rating, 293 reviews

Relaxing 3 Bedroom Cottage in Quiet Neighborhood

This happy 3 bedroom duplex will be a family favorite on your next trip to Southern Illinois. You'll enjoy 3 cozy bedrooms each equipped with a TV, 1 bathroom, ample deck space and firepit. We are located on a quiet street within walking distance of all Carbondale has to offer – Downtown Carbondale, restaurants and pubs (.8 miles), the Memorial Hospital of Carbondale (.5 miles), Carbondale Civic Center (.8 miles), Amtrak Station (.9 miles), and SIU (1.1 miles).

Top guest favorite
A hand-hewn oak timber cabin is positioned amidst a natural setting, showcasing rustic wooden siding and a welcoming porch. The structure is surrounded by trees and greenery, with steps leading to the entrance, emphasizing a connection to the outdoors.
Cabin in Anna
4.9 out of 5 average rating, 174 reviews

Contemporary Glamping with Native American Appeal!

Luxury Glamping with a taste of Native America! Stay in a hand-hewn oak timber cabin, on the historical "Trail of Tears" in Union County, Illinois. This lodging offers the rustic appeal of an authentic cabin in the woods, with the all the creature comforts and all year around outdoor hot tub. *If you do not find your desired date available, be sure and check our twin cabin listing at AdamsRock Cabins, Cabin #1.

Top guest favorite
A serene cabin sits amidst lush greenery, surrounded by trees that reflect in a tranquil pond. A well-kept lawn leads up to the entrance, enhancing the peaceful setting. Blossoming branches frame the scene, adding a touch of nature’s elegance.
Cabin in Cobden
4.97 out of 5 average rating, 125 reviews

Unique luxury cabin with fireplace and pond view

Shawnee Pond Retreat is a two-bedroom countryside haven that sits on a ridge in the Shawnee National Forest. Located just outside Alto Pass near numerous vineyards, lakes and hiking trails, it is a perfect destination for friends, couples, or families. Shawnee Hills Wine Trail has 11 wineries nearby. With its impressive bluffs and spectacular trailways, Giant City State Park is just a 15-minute drive.

Top guest favorite
A serene private lake is surrounded by lush trees, reflecting a blue sky. A kayak is on the water, while a small wooden ladder leads to the water's edge. Smooth stones line the shore, creating a peaceful setting for relaxation or water activities.
Cabin in Du Quoin
4.97 out of 5 average rating, 155 reviews

H & B's...Come experience the magic of nature!

The Cabin is nestled in the woods, a few hundred feet from a beautiful private lake. If it's total solitude you are looking for, this is the place. Keyless entry makes it perfect if you want total privacy. If you want lake access, come down and have coffee with us for orientation. Our pantry items, coffee, granola, half & half, and spices are perfect for your full-service kitchen.

Top guest favorite
A charming bungalow is set within a manicured yard, featuring a gravel driveway leading up to the house. Lush green grass borders flower beds with decorative plantings. The home showcases a covered porch with blue accents, inviting outdoor relaxation amidst a peaceful neighborhood.
Home in Carterville
4.99 out of 5 average rating, 209 reviews

Sweet Peas Bungalow

Relax with the whole family at this peaceful bungalow. Centrally located between Marion and Carbondale. Enjoy outdoor activities with a scenic drive to Crab Orchard and Fern Cliff. And just 15 miles away from the ever popular Wine Trail of Southern Illinois. Take a short five minute drive to Walkers Bluff Casino and Resorts.

Popular amenities for De Soto vacation rentals

  1. Airbnb
  2. United States
  3. Illinois
  4. Jackson County
  5. De Soto