Guesthouse vacation rentals in Panamá Oeste

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Top-rated guesthouse rentals in Panamá Oeste

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Top guest favorite

The living area features large glass doors that invite natural light and views of the garden. Indoor plants enhance the space, and a cozy seating arrangement includes a sofa and eclectic chairs. A workspace with a desk and lamp is positioned to the side.

Guesthouse in El Valle de Antón

Spacious Casita with Bamboo View

Walk 20 minutes to the artisan mercado and restaurants on Ruta 71. Cerro Cara Iguana trailhead is walking distance from the casita. High insulated ceilings and 2 ceiling fans for comfort. Private hammock patio for an afternoon nap. Washer/dryer in the casita. Hot water throughout. Kitchen has a 2 burner cooktop, countertop oven, microwave, instant pot, electric skillet, blender and coffee maker. 2 Internet providers and a small workspace available. * No television set * Non smoking property

LocationValueBathroom

4.99 out of 5 average rating, 131 reviews

Guest favorite

Guesthouse in El Valle de Antón

The Retreat in El Valle - Casita de la Montaña

Welcome to your serene retreat in El Valle, Panama! Nestled amid lush nature, our two-bedroom casitas offer a peaceful escape with breathtaking views, exotic wildlife, and flora. Each casita features two rooms, including a queen bed, choice of king or twin beds, a small fridge, coffee station, Wi-Fi, and large terrace with comfy couch. Enjoy the shared pool, book meditation/ healing sessions, explore world-class hiking. Enjoy next door La Compania restaurants, El Valle’s famous artisan market!

ValueFamilyView

4.92 out of 5 average rating, 118 reviews

Top guest favorite

A charming apartment building is nestled among lush greenery and tall trees. The exterior features a welcoming porch with railings and is surrounded by tropical plants, creating a serene environment. Natural sunlight filters through the leaves, highlighting the vibrant foliage.

Guesthouse in Gamboa

Gamboa Toucan Apartment casa # 126

Welcome to Gamboa! Only 35 minutes from downtown Panama, Gamboa. Situated in Soberanía National Park and on the shores of the Panama Canal, is a Mecca for Birdwatchers and Nature enthusiasts! Watch the wildlife right from the backyard of your fully equipped apartment. Feel the magic songs of thousands of birds welcoming the twilight of sunrise and dusk in this century old community. Easily explore wildlife on trials through the surrounding old growth jungle and by boat on the Panama Canal.

ValueLocationAir conditioning

4.94 out of 5 average rating, 87 reviews

Superhost

Guesthouse in Las Lajas

08-Casita Colibri, new 2026. Near Beach, big pool!

Nestled a short stroll from the beach and all that Coronado offers, you’ll discover a private enclave of five FULLY equipped vacation apartments. Refreshing pool & flourishing gardens. Casita Colibri, in our newest collection of casita, so now, by popular demand, we have 5 casitas! This casita was lovingly constructed this year, 2025..while we closed for 3 months upgrading the property, from new roof, ceilings, electrical, grass, we've done it all! Double bed, full kitchen, AC , WIFI / TV

LocationHospitalityPool

4.86 out of 5 average rating, 7 reviews

Guest favorite

A private swimming pool with a waterfall is surrounded by lush greenery, providing a tranquil setting. A thatched-roof structure is visible nearby, creating an inviting space for relaxation. Colorful flowers and plants enhance the outdoor area, making it suitable for leisurely outdoor dining.

Guesthouse in Rio Hato

Sustainable Guest house with Pool in Rio Hato

Discover Rancho Ahome, a serene 2BR 1Bath guesthouse in Rio Hato. Escape to tranquility, 5 mins from stunning beaches, and enjoy our private pool with a waterfall. Immerse in nature on our sustainable farm, home to fruits, rabbits and chickens. Perfect for those seeking peace and an eco-friendly retreat, Rancho Ahome offers a blend of comfort and adventure amidst breathtaking landscapes. Experience a peaceful sanctuary that’s close to nature yet filled with comfort. We are pet friendly.

FamilyLocationPool

4.9 out of 5 average rating, 126 reviews

Guest favorite

The Sky Cabin is surrounded by vibrant tropical foliage and flowering plants, showcasing a colorful exterior. A stone pathway leads to the cabin, with a covered outdoor area visible, ideal for enjoyment in the garden's serene environment.

Guesthouse in La Ermita

Sky Cabin/Rural+AC, WiFi, hot water, pool, private

The Sky Cabin is part of 5 cabins “A Piece of Paradise” With registration in the Panamanian Tourism Authority Bureau. ✸ Ideal for a couple or a single person ✸ Outdoor dining area and kitchen ✸ Spacious terrace with a hammock ✸ Very quiet neighborhood ✸ Private and public transportation available, just ask and we will help you ✸ 7-10 minutes, by car, from Playa La Ermita and 10 minutes from Playa El Palmar (great spot for surfing) ✸ Breakfast for an additional $7.00, for each guest.

FamilyLocationAir conditioning

4.96 out of 5 average rating, 131 reviews

Guest favorite

Guesthouse in Chame

Apartment accommodation near the beach and river

2 bedroom apartment with air conditioning for 5 people. It has 450 mb internet, cable TV, smart TV, wifi, hot water, kitchen, a small dining room, 1 queen bed and 3 3/4 beds in a second bedroom, terrace with breakfast table in the open air, small barbecue, a few minutes from rivers, beaches and shopping centers, supermarkets and restaurants, beaches Gorgona, Coronado, Vista Mar, Malibu, Playa Teta, Playa Caracol for surfers. 30 minutes away from Los Cajones de Chame tourist site.

ValueLocationIndoor spaces

4.83 out of 5 average rating, 54 reviews

Top guest favorite

The indoor/outdoor kitchen area features colorful wall murals and is equipped with a refrigerator, stove, and dining table with chairs. A vibrant hammock hangs in the space, inviting relaxation amid the bright décor and natural light.

Guesthouse in Near La India Dormida Tourist Trailhead, Unnamed Road Casa 30, El Valle de Antón, Coclé Province, Panama

Private 1 BR cottage near India Dormida hiking

This private fully equipped 1 bedroom casita has been a high rated Super Host Airbnb favorite for years. Relax into the hammocks in this peaceful residential setting where birds and butterflies abound. The kitchen/dining area opens to a wonderful private garden and gives you a fantastic view of India Dormida mountain and nearby hiking trail. A short (~20 minute) walk to the town with shops, restaurants and daily Farmers Market featuring fresh fruits/vegetables & local crafts

ValueLocationIndoor spaces

4.92 out of 5 average rating, 87 reviews

Top guest favorite

A tranquil outdoor area is depicted, featuring a small private pool surrounded by lush greenery. The charming cottage stands nearby, characterized by large windows and a covered porch that offers ample natural light.

Guesthouse in Panamá Oeste

Mountain cabin with private pool in Panama

Enjoy peace and nature in this cozy and equipped cabin, perfect for disconnecting and relaxing. Surrounded by forests and spectacular views, here you can breathe fresh air and gaze at the stars. ✔️ Ideal for couples, families or adventurers. ✔️ Trails, rivers and viewpoints nearby. ✔️ Comfortable and equipped spaces for your comfort. - Sleeps 4 people. - Discount for two nights or more. Close to: Laguna de San Carlos, Valle de Antón, beaches of the Panamanian Pacific.

ValueFamilyAmenities

4.81 out of 5 average rating, 200 reviews

Guest favorite

A stone guesthouse with a traditional thatched roof is surrounded by lush greenery. Banana plants and palm trees are visible in the foreground, while a small outdoor seating area with chairs is featured in front of the house, providing a welcoming ambiance.

Guesthouse in Santa Rosa

Chagres River Lodge

You stay in our guest house on the River Chagres, in the village Santa Rosa. it is a stone house with a beautiful Panama rancho over it, so the house stays nice and cool. In our garden you have large trees with many birds such as parrots. We have a sloth in the tree. In the morning you can hear the monkeys on the other side and you can explore the area with the canoe. Or take a dip in the river to cool off. A boat to Gamboa or the Panama Canal is a 20 minute boat ride.

LocationFamilyRiver

5.0 out of 5 average rating, 12 reviews

Superhost

Guesthouse in Ancon

Ancon Garden Studio - Panama City | Fast WiFi

Nestled in the historic former Canal Zone, this cozy studio is ideal for remote work and easy city access. Enjoy fast WiFi, a dedicated workspace, and a peaceful green setting near Cerro Ancón, the Panama Canal Railway Station, City of Knowledge, and Albrook Metro. Just a short walk away is Los Ríos Pool, a popular swimming facility perfect for lap swimming, exercise, or cooling off after a day of exploring. Also, bikes are available upon request.

LocationWifiWalkability

5.0 out of 5 average rating, 4 reviews

Top guest favorite

Guesthouse in El Valle de Antón

Flor del Aire Cabin

Welcome to our Flor del Aire cabin. A private and cozy retreat, for up to 3 people. The cabin is surrounded by a large garden where you can enjoy the local biodiversity. We have a well-equipped kitchen and shower with hot water. *Private parking. *Wi-Fi-free space, an ideal opportunity to disconnect. For those who need Wi-Fi there is an excellent coffee shop just a few meters away. *We are pet friendly.

FamilyLocationPets

4.94 out of 5 average rating, 64 reviews