Vacation rentals in Pamplico

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Top-rated vacation rentals in Pamplico

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite

Guesthouse in Conway

4.98 out of 5 average rating, 152 reviews

Cozy Cottage

This adorable guest house is situated in a lovely neighborhood in the quaint river town of Conway, SC. A beautiful pool and deck area is available several months of the year. 8 miles from Coastal Carolina University make it a great place to stay for attending student events. Historic downtown Conway offers a delightful river walk along the banks of the Waccamaw River, along with an array of shopping, dining and historic attractions. Conway is also just 12 mi. inland from Myrtle Beach.

Jul 12 – 19

G$18,019 GYD per night

Guest favorite

Place to stay in Effingham

4.96 out of 5 average rating, 100 reviews

Gated and Private Catholic Hermitage house

Saint Michael Hermitage and retreat is a serene, gated, private home that is for 1-3 guests looking for a quiet stay while traveling or as a retreat destination. You will self check into your Hermitage after you obtain a gate code. There is a prayer chapel close by on the property. It is pet friendly for a well trained pet. There is Catholic iconography throughout the home. It is warm and inviting. There is a full kitchen, washer/dryer for your convenience and complementary coffee/tea.

Jun 13 – 20

G$30,685 GYD per night

Guest favorite

Apartment in Florence

4.91 out of 5 average rating, 258 reviews

Kuker Carriage House-Sleeps 3-Downtown/Near I95&20

Kuker Carriage House was originally a barn that has been converted into apartments in the heart of the newly revitalized Florence downtown. This first floor unit was just fully renovated and is ready for you to enjoy, whether for a short overnight stop or a longer extended stay. This space is bright and open with lots of natural light and a fully enclosed private courtyard. Queen bed, twin daybed, full bath, Wifi and TV. Walkable to parks and restaurants. Just 4 miles from I95 and I20

Jun 2 – 9

G$31,332 GYD per night

Guest favorite

Guest suite in Florence

4.87 out of 5 average rating, 428 reviews

Private Apartment 5 Min Away From I-95 & I-20

Please come and enjoy our Guest Apartment in Florence, SC! A great stop for travelers to rest during their trips. Guests will have a private entrance to the apartment that is attached but separate from the main house, where me and my family live. Guest privacy will always be respected. One bedroom has a queen size bed, a second bedroom has a daybed. The bathroom has a tub and shower. The kitchen has a stove/oven. The apartment is cleaned and sanitized after each guest leaves. Thank you!

Aug 1 – 8

G$25,044 GYD per night

Guest favorite

Home in Georgetown

4.99 out of 5 average rating, 118 reviews

Black River Refuge on the Water

The first guest comment I hear is "Wow - pictures don't do this place justice - the house is incredible and the views are spectacular!" The next comment is "I thought we were way out in the country but it's only 20 minutes to the waterfront town of Georgetown, with shops, dining, museums and more. Looking to get away? This place is truly a retreat- a 3 bedroom house on the beautiful Black River in Georgetown. Kayaks provided, swim or fish off the dock just a few steps from the house.

Dec 16 – 23

G$38,043 GYD per night

Guest favorite

Home in Lake City

4.91 out of 5 average rating, 178 reviews

Home Away From Home Apt 3 - A Hidden Gem

Stand Alone (not a part of the main house) 1 Bed-Room Apt. with Full furnished Kitchen, Full Bath, Private Entrance, private bedroom with door, Private Parking. Living Room- Dining Combo. Fully Furnished. High-Speed WI-Fi, 2 ROKU TVs, 1 in BR & 1 in LR, 1/2 way from New York to Miami, Hablamos Espanol, Fresh Brewed In-Room Coffee. Easy 1-mile walk on Main St. to uptown. 23 miles from I-95, 60 miles to Myrtle Beach, 23 miles to Florence, 1&1/2 hours to Charleston and Columbia.

May 10 – 17

G$12,743 GYD per night

Guest favorite

Farm stay in Hemingway

4.97 out of 5 average rating, 158 reviews

Quiet farmhouse near the beach

The best memories are made on the farm. Life is just better away from the hustle and bustle of city lights and busy schedules. Come stay in this recently renovated fourth generation 1950s farmhouse on an 80 acre working farm. Unwind on the porch, walk trails, find millions of years old sharks teeth, build a bonfire, pick blackberries, swim in the ponds, collect walnuts, or just relax while you’re here but don’t forget to wish on a dandelion or a shooting star before you leave.

Nov 12 – 19

G$23,143 GYD per night

Guest favorite

Cottage in Timmonsville

4.97 out of 5 average rating, 792 reviews

*Cottage Near Florence and I-95*

Located just 5 mins from I-95 (exit 153) and 12 minutes from Florence, this quaint cottage sits on 6 acres with private deck, firepit & large back yard in a peaceful, country location. Your pets are welcome (max of 2, please). We offer king bed in master, 3 wall-mounted TV's (two 55” & one 32”), coffee bar with Keurig, strong WiFi. We also use 100% cotton sheets and quilts for your maximum sleeping comfort. Lock Box on front door for self-check-in! Come stay with us. 🙂

Oct 16 – 23

G$27,410 GYD per night

Guest favorite

Guesthouse in Florence

4.93 out of 5 average rating, 679 reviews

The Poolside Cottage: Close to Interstates

New floors and paint in January of 2023. Palm Trees, colorful flowers, hammocks and quiet space await in this tropic-like oasis just minutes from I-95/20. Hundreds of reviews acknowledge this idyllic setting. We are a Florence Airbnb favorite for travelers. We offer a queen bed, full bathroom, queen sleeper sofa, strong wifi and TV. We even provide breakfast bars and coffee to help you jump start your day as you set off for the next journey. We look forward to hosting you.

Jun 13 – 20

G$21,959 GYD per night

Guest favorite

Guesthouse in Florence

4.99 out of 5 average rating, 664 reviews

Boho Private Downtown Stay Near I-95 & Hospital

Comfort, cleanliness, privacy, and personality! Perfect for overnight stays or longer terms. Come enjoy our Boho hideaway in the heart of Florence. Our place has all the amenities of a hotel with the comfort and privacy of your own home including parking for two vehicles. We are located within walking distance to downtown Florence and a 5 minute drive to all of the restaurants and shopping that Florence has to offer. Come stay at our guest house and make yourself at home!

May 17 – 24

G$26,268 GYD per night

Guest favorite

Loft in Conway

5.0 out of 5 average rating, 128 reviews

Get away to Conway

Just two miles from downtown Conway and all it has to offer and 5 miles from Coastal Carolina University. A studio style apartment with a king size bed and a queen size sleeper sofa if you should need it. Complete with black out curtains so getting some shut eye is always an option. We are a family of 5 living on the same property but will always be courteous of our guests being sure to stay out of the way. No motorcycles or pets are permitted. Cameras are on the premises.

Apr 15 – 22

G$20,293 GYD per night

Guest favorite

Treehouse in Marion

4.99 out of 5 average rating, 174 reviews

Enchanting Treehouse with Modern Amenities

Perched on 20 acres along Catfish Creek, this enchanting tree house allows you to appreciate nature from a birds eye view. Whether it’s kayaking, canoeing, or exploring along the creek; relaxing in the hammocks and swings; engaging in a board game; or roasting marshmallows at the fire pit, Amenities include a full kitchen with full bath, outdoor shower, booth seating in dining table for up to 8, 2 bunk beds and loft style sleeping.

Dec 8 – 15

G$58,650 GYD per night