
Vacation rentals in North Santee River
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Top-rated vacation rentals in North Santee River
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Luxury/Comfort home 3bedrooms/2 full baths
Unwind in this beautifully designed home, offering the perfect blend of comfort, and Southern charm. Whether you’re visiting for a relaxing getaway, a family vacation, or a business trip, this space has everything you need ✔ Stylish & spacious living areas ✔ Fully equipped kitchen✔ Comfortable bedrooms✔ Fast WiFi & Smart TV✔ Peaceful location, just minutes from historic Georgetown & local attractions.Nestled in the heart of Georgetown, close to scenic waterfront views, charming shops, and dining

Unique New Remodel Close to Beach and Golf
Fully remodeled, the little cabin on the marsh is a 1 BR house with a loft. Inside is almost all wood. The house sits on the marsh water of the Waccamaw river. The neighborhood is a dirt road with a mix of mobile homes and houses. The neighbors are great and have lived on the street for decades. The house is surrounded by live oaks, nature and tidal marsh water in the backyard. Litchfield and Pawleys Island beaches are 5 minutes away. World class golf, restaurants, and grocery stores are near.

Porch Paradise in Historic Georgetown, Harborwalk
Step back in time in this charming 19th Century Home in Historic Georgetown, SC. Just a short stroll from the scenic riverfront, this timeless gem blends historic character without sacrificing comfort. The home features iconic double front porches, perfect for morning coffee or evening breezes under the canopy of century-old live oak trees lining a quiet, picturesque street. Just minutes on foot from rich coastal culture, charming shops, waterfront dining, museums, festivals, parks and marina.

Black River Refuge on the Water
The first guest comment I hear is "Wow - pictures don't do this place justice - the house is incredible and the views are spectacular! The next comment is "I thought we were way out in the country but it's only 20 minutes to the waterfront town of Georgetown, with shops, dining, museums and more. Looking to get away? This place is truly a retreat- a 3 bedroom house on the beautiful Black River in Georgetown. Four kayaks provided, swim or fish off the dock just a few steps from the house.

Georgetown Vogue in the Heart of the City
Located on Front St in the heart of historic Georgetown, this 1 BR, 1 Bath, full kitchen, apartment is located on the second floor of a smartly designed, mixed use, Charleston-style building. Surrounded by restaurants, museums, theater, Harborwalk, and shops, this apartment accommodates 2 in a no smoking environment and offers high speed internet, and large screen TV. No pets. Guests enjoy a quiet setting together with 1 free pass per occupant to the Purr & Pour Cat Café. Free parking.

Maggie Jo’s paradise on the river !
Reconnect with nature at this unforgettable escape. Maggie jo is a 1970 completely restore houseboat. She has got a full size refrigerator , gas range ,microwave and toaster oven. Out on the back deck she has a gas grill. The aft berth has 2 full beds that are extremely comfortable. Galley dinette make into bed and the couch in the saloon pulls out also. While on the decks you will see eagles, dolphins , gator or fishing jumping out of the water. I also have 2 tandem kayaks for your use.

Dolphin Point: Beautiful bungalow w/ private dock
King Beds, large outdoor space with fire pit, beautiful dock views at sunrise and sunset… names a few of our many amenities - 1,128 Sq Ft Home - Minutes from historic Georgetown/Winyah Bay and near Pawleys Island and the surrounding areas - Extensive parking, large outdoor screened in porch, outdoor swing and shower station, and updated appliances. Permit Number: 00000745 Business License: 12000211 Streaming services: Netflix, Hulu, HBO Max, Youtube TV, Disney+, ESPN+, Prime Video

Antique Tugboat on the Harborwalk
Welcome aboard this lovingly restored antique tugboat, moored just steps from the storied streets of Georgetown. Once a proud workhorse of American waterways, this vessel now offers a rare opportunity to experience life as it was in 1907—without sacrificing comfort. Let the scent of old pine and briny air greet you each morning as the harbor stirs to life. Cradle a warm mug of coffee as the sun lifts above the horizon, painting the masts and marshes in amber light. Your voyage awaits.

#1 The Lodge- Private Cabin + Hot Tub + More
The Only Luxury Escape in the Heart of the Santee Delta’s Untouched Beauty! A Private Luxury Cabin Experience The Lodge is now a stunning retreat with Scandinavian Design. Accommodating up to 8 guests, it features a king master suite, loft with four twin beds, and pull-out sofa for two. Outside, relax on a screened-in porch, rocked patio with hot tub, gas grill, Adirondack chairs, and Solo Stove. The chef’s kitchen includes a gas stove, microwave, full size fridge, Keurig and more.

Lo & Billy’s Place a Historic 1940s Newlywed Cabin
This romantic cabin located on our small farm just outside of town in the country offers a history all its own. Lo was Billy’s nickname for Lorene Ella. Lo & Billy got married in the 1950s and lived here. Renovated after meeting Lo and hearing her stories. We pay homage to the rich history of Georgetown and the Southerners that have called Lo & Billy’s Place home. Heavy on coziness & design. Full kitchen; good coffee; & comfy queen bed w/high end linens. The perfect escape.

Resort @ Kit Hall Pool & Gardens, near Charleston
Centrally located between Myrtle Beach, Mount Pleasant and Charleston SC ( closest beach 36 miles by car. A sanctuary with an amazing freshwater (not chlorine or salt but Ionized)swimming pool, between two national parks, The Francis Marion National Forest & Cape Romain Wildlife Refuge. Near waterways, hiking, cycling trails, fishing, low country dining, historical plantations and more. 2 bedrooms & a screened sleeping porch. 4 beds + library, kitchenette & 2 ba

Private Pondside Guest Suite
This peaceful guest suite is a full private studio apartment connected to our home with a private entrance-perfect for families, boaters, hunters, or those traveling for work. Parking on the premises is available for boats, trailers, and similar vehicles. We also offer charging for your boat battery-just let us know in advance so we can accommodate your needs. Your private getaway awaits!
Popular amenities for North Santee River vacation rentals
Other great vacation rentals in North Santee River

Architecture* La Cabaña * Beach 8 min * 2 Bedrooms

*Swamp Fox Retreat < 1 mile to Downtown

Poolside Villas @ Winyah Bay Club!

One-of-a-Kind 4BR on 18th Hole

River Dome Retreat

The Wrenn’s Nest - Quaint National Forest Getaway

Hidden Oasis

Winyah Bay House | Historic Georgetown Waterfront
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