Vacation rentals in North Santee River

Downtown Georgetown SC Historic 2BR

Welcome to this charming 2 bedroom, 2 bathroom apartment in a beautifully renovated historic home. The property is located in the heart of historic downtown Georgetown, SC. Across the street you'll find the harborwalk and public dock- perfect to arrive by boat and walk to. Walkable to restaurants and shop Take a walk along the boardwalk and watch the fishing boats come in or spend the day shopping in the quaint historic village and enjoy fresh local seafood at the many wonderful restaurants.

Luxury/Comfort home 3bedrooms/2 full baths

Unwind in this beautifully designed home, offering the perfect blend of comfort, and Southern charm. Whether you’re visiting for a relaxing getaway, a family vacation, or a business trip, this space has everything you need ✔ Stylish & spacious living areas ✔ Fully equipped kitchen✔ Comfortable bedrooms✔ Fast WiFi & Smart TV✔ Peaceful location, just minutes from historic Georgetown & local attractions.Nestled in the heart of Georgetown, close to scenic waterfront views, charming shops, and dining

Unique New Remodel Close to Beach and Golf

Fully remodeled, the little cabin on the marsh is a 1 BR house with a loft. Inside is almost all wood. The house sits on the marsh water of the Waccamaw river. The neighborhood is a dirt road with a mix of mobile homes and houses. The neighbors are great and have lived on the street for decades. The house is surrounded by live oaks, nature and tidal marsh water in the backyard. Litchfield and Pawleys Island beaches are 5 minutes away. World class golf, restaurants, and grocery stores are near.

Above It All with Southern Style

Located on Front St in the heart of historic Georgetown, this 2 BR/2 BA, full kitchen, 1200 SF apartment with large balcony is located on the 2nd floor of a smartly designed, mixed use, Charleston-style building. Surrounded by restaurants, museums, theater, Harborwalk, and shops, this beautiful apartment accommodates 4, offers high speed WiFi, and a large screen TV. Guests enjoy a quiet setting with 1 free pass per occupant to the Purr & Pour Cat Café. Free parking. No smoking or pets.

Black River Refuge on the Water

The first guest comment I hear is "Wow - pictures don't do this place justice - the house is incredible and the views are spectacular! The next comment is "I thought we were way out in the country but it's only 20 minutes to the waterfront town of Georgetown, with shops, dining, museums and more. Looking to get away? This place is truly a retreat- a 3 bedroom house on the beautiful Black River in Georgetown. Four kayaks provided, swim or fish off the dock just a few steps from the house.

Maggie Jo’s paradise on the river !

Reconnect with nature at this unforgettable escape. Maggie jo is a 1970 completely restore houseboat. She has got a full size refrigerator , gas range ,microwave and toaster oven. Out on the back deck she has a gas grill. The aft berth has 2 full beds that are extremely comfortable. Galley dinette make into bed and the couch in the saloon pulls out also. While on the decks you will see eagles, dolphins , gator or fishing jumping out of the water. I also have 2 tandem kayaks for your use.

Antique Tugboat on the Harborwalk

Welcome aboard this lovingly restored antique tugboat, moored just steps from the storied streets of Georgetown. Once a proud workhorse of American waterways, this vessel now offers a rare opportunity to experience life as it was in 1907—without sacrificing comfort. Let the scent of old pine and briny air greet you each morning as the harbor stirs to life. Cradle a warm mug of coffee as the sun lifts above the horizon, painting the masts and marshes in amber light. Your voyage awaits.

Lo & Billy’s Place a Historic 1940s Newlywed Cabin

This romantic cabin located on our small farm just outside of town in the country offers a history all its own. Lo was Billy’s nickname for Lorene Ella. Lo & Billy got married in the 1950s and lived here. Renovated after meeting Lo and hearing her stories. We pay homage to the rich history of Georgetown and the Southerners that have called Lo & Billy’s Place home. Heavy on coziness & design. Full kitchen; good coffee; & comfy queen bed w/high end linens. The perfect escape.

Billfish Bungalow Georgetown, SC

✨The Billfish Bungalow offers a one of a kind cozy feel for your stay with friends and family. Located in Georgetown, SC, this home is the perfect spot for a stay on your next fishing trip, girls weekend, or trip to explore historic Georgetown. The Billfish has a unique atmosphere, with views of the marsh and a place to sit and enjoy it. It sits 3 minutes from the closest boat ramp, 6 minutes from downtown Georgetown, and 21 minutes from beach access at Pawleys Island.

Resort @ Kit Hall Pool & Gardens, near Charleston

Centrally located between Myrtle Beach, Mount Pleasant and Charleston SC ( closest beach 36 miles by car. A sanctuary with an amazing freshwater (not chlorine or salt but Ionized)swimming pool, between two national parks, The Francis Marion National Forest & Cape Romain Wildlife Refuge. Near waterways, hiking, cycling trails, fishing, low country dining, historical plantations and more. 2 bedrooms & a screened sleeping porch. 4 beds + library, kitchenette & 2 ba

True Blue Retreat

Pawleys Island has been a vacation destination since the 1700s and it remains charming yet laid back. The beach is unspoiled and un-commercialized, while the area is full of unique boutiques and restaurants. Pawleys Island has the great food and fun of Charleston, without the expense, and the golf of Myrtle Beach, without the crowds. Follow us @jointheranks to learn more about Pawleys Island and how to make the most of your stay.

Casa Zoë | Historic Garden Carriage House CHS

OP2026-07206 A hidden gem in the heart of Charleston, Gibbon House is a beautifully restored brick carriage house with a story to tell. Once the office space for the Charleston Symphony Orchestra, it now offers elegant, design-forward hospitality just steps from King Street. Featured in Condé Nast Traveler, Gibbon House combines history, charm, and comfort with Casa Zoë’s signature warmth and character.