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Vacation rentals in North Santee River

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Top-rated vacation rentals in North Santee River

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
Home in Pawleys Island
4.94 out of 5 average rating, 189 reviews

Unique New Remodel Close to Beach and Golf

Fully remodeled, the little cabin on the marsh is a 1 BR house with a loft. Inside is almost all wood. The house sits on the marsh water of the Waccamaw river. The neighborhood is a dirt road with a mix of mobile homes and houses. The neighbors are great and have lived on the street for decades. The house is surrounded by live oaks, nature and tidal marsh water in the backyard. Litchfield and Pawleys Island beaches are 5 minutes away. World class golf, restaurants, and grocery stores are near.

Top guest favorite
The exterior of a two-story house is nestled among tall trees, showcasing a deck with steps leading to the ground. Screened-in porches on both levels provide ample outdoor space and views of the surrounding greenery.
Home in Georgetown
4.98 out of 5 average rating, 184 reviews

Black River Refuge on the Water

The first guest comment I hear is "Wow - pictures don't do this place justice - the house is incredible and the views are spectacular! The next comment is "I thought we were way out in the country but it's only 20 minutes to the waterfront town of Georgetown, with shops, dining, museums and more. Looking to get away? This place is truly a retreat- a 3 bedroom house on the beautiful Black River in Georgetown. Four kayaks provided, swim or fish off the dock just a few steps from the house.

Top guest favorite
The living area features a light blue wall, complemented by framed artwork. A bright red loveseat and a dark brown sofa with colorful cushions provide seating. A glass coffee table rests on a textured dark rug, while a wooden cabinet and a television complete the space.
Apartment in Georgetown
4.98 out of 5 average rating, 319 reviews

Georgetown Vogue in the Heart of the City

Located on Front St in the heart of historic Georgetown, this 1 BR, 1 Bath, full kitchen, apartment is located on the second floor of a smartly designed, mixed use, Charleston-style building. Surrounded by restaurants, museums, theater, Harborwalk, and shops, this apartment accommodates 2 in a no smoking environment and offers high speed internet, and large screen TV. No pets. Guests enjoy a quiet setting together with 1 free pass per occupant to the Purr & Pour Cat Café. Free parking.

Superhost
A serene sunset casts warm hues over the water, with a houseboat moored alongside a covered dock. Silhouetted against the sky, fishing rods stand tall, and tall grasses frame the scene, enhancing the tranquility of this riverside setting.
Home in Georgetown
4.88 out of 5 average rating, 161 reviews

Maggie Jo’s paradise on the river !

Reconnect with nature at this unforgettable escape. Maggie jo is a 1970 completely restore houseboat. She has got a full size refrigerator , gas range ,microwave and toaster oven. Out on the back deck she has a gas grill. The aft berth has 2 full beds that are extremely comfortable. Galley dinette make into bed and the couch in the saloon pulls out also. While on the decks you will see eagles, dolphins , gator or fishing jumping out of the water. I also have 2 tandem kayaks for your use.

Top guest favorite
Cottage in Georgetown
5 out of 5 average rating, 19 reviews

Charming Coastal Cottage in Historic Georgetown

Welcome to this unique Orange Street Cottage in the heart of Historic Georgetown, SC. The cottage dates back to 1910 and includes two-bedrooms and two-bathrooms. It is located three blocks from Front Street and the historic waterfront. Take a walk along the Harborwalk or spend the day shopping, eating fresh seafood or having a beverage in the many waterfront restaurants. The cottage has a full kitchen, cozy living room, covered outside area with tv, fire pit and a large back yard.

Guest favorite
A warm living area showcases natural wood paneling and large windows, allowing ample light. A sleek coffee table is centered among comfortable seating, including a cozy sofa and stylish accent chairs. A staircase is visible in the background, enhancing the open layout.
Cabin in Georgetown
5 out of 5 average rating, 9 reviews

#1 The Lodge- Private Cabin + Hot Tub + More

The Only Luxury Escape in the Heart of the Santee Delta’s Untouched Beauty! A Private Luxury Cabin Experience The Lodge is now a stunning retreat with Scandinavian Design. Accommodating up to 8 guests, it features a king master suite, loft with four twin beds, and pull-out sofa for two. Outside, relax on a screened-in porch, rocked patio with hot tub, gas grill, Adirondack chairs, and Solo Stove. The chef’s kitchen includes a gas stove, microwave, full size fridge, Keurig and more.

Top guest favorite
The entrance of the cabin features a modern black exterior with a circular welcome mat and a stylish door showcasing large glass panes. Potted white flowers add a touch of nature, while an outdoor chair invites relaxation amidst the greenery of surrounding trees.
Farm stay in Georgetown
4.99 out of 5 average rating, 72 reviews

Lo & Billy’s Place a Historic 1940s Newlywed Cabin

This romantic cabin located on our small farm just outside of town in the country offers a history all its own. Lo was Billy’s nickname for Lorene Ella. Lo & Billy got married in the 1950s and lived here. Renovated after meeting Lo and hearing her stories. We pay homage to the rich history of Georgetown and the Southerners that have called Lo & Billy’s Place home. Heavy on coziness & design. Full kitchen; good coffee; & comfy queen bed w/high end linens. The perfect escape.

Guest favorite
The living area features exposed wooden beams and a rustic brick fireplace, creating a warm gathering space. A dining table is set with tableware, while comfortable seating is arranged for relaxation. Sunlight filters through the window shutters, enhancing the inviting ambiance.
Apartment in Georgetown
4.93 out of 5 average rating, 107 reviews

Charming apartment in the heart of downtown!

Welcome to this charming 2 bedroom, 2 bathroom apartment in a beautifully renovated historic home. The property is located in the heart of historic downtown Georgetown, SC. Across the street you'll find the harborwalk and public dock- perfect to arrive by boat and walk to. Take a walk along the boardwalk and watch the fishing boats come in or spend the day shopping in the quaint historic village and enjoy fresh local seafood at the many wonderful restaurants.

Top guest favorite
Guest suite in McClellanville
4.96 out of 5 average rating, 153 reviews

Resort @ Kit Hall Pool & Gardens, near Charleston

Centrally located between Myrtle Beach, Mount Pleasant and Charleston SC ( closest beach 36 miles by car. A sanctuary with an amazing freshwater (not chlorine or salt but Ionized)swimming pool, between two national parks, The Francis Marion National Forest & Cape Romain Wildlife Refuge. Near waterways, hiking, cycling trails, fishing, low country dining, historical plantations and more. 2 bedrooms & a screened sleeping porch. 4 beds + library, kitchenette & 2 ba

Superhost
Home in Georgetown
4.78 out of 5 average rating, 72 reviews

Winyah Bay House | Historic Georgetown Waterfront

PROPERTY NAME: WINYAH BAY HOUSE - NO PETS 408 Sassanqua Drive, Georgetown, South Carolina, 29440 NO SMOKING ON PREMISES AGE REQUIREMENT: Guests under the age of 25 must be accompanied by a responsible parent or guardian to book a property. Please note that the fireplace is currently not available for guest use.SLEEPING ARRANGEMENTS: Sleeps 8 comfortably. Primary Bedroom: King Bed Guest Bedroom: King Bed Guest Bedroom: King Bed Guest Bedroom: 2 Twins

Guest favorite
A large swimming pool is framed by a spacious patio, with lounge chairs and an umbrella nearby. A two-story cottage is positioned in the background, featuring a balcony with steps leading down to the pool area. Lush greenery surrounds the setting.
Guesthouse in Pawleys Island
4.95 out of 5 average rating, 110 reviews

1 BR Cottage/ Pool / Golf Cart/Near Beach

This is the perfect getaway for someone wanting peaceful surroundings, but wants access to all the action. The cottage includes a full bath, kitchenette, micro-wave, fridge, 2 burner stove, garbage disposal, TV, AC/heat, wifi, and its own balcony that overlooks the beautiful pool. You will have use of the pool, grills, fire pit and the golf cart. The beach is just a short 3 mile cart or car drive. Close to Myrtle B., Murrells Inlet & Georgetown

Top guest favorite
A spacious living area is highlighted by wooden flooring and natural light. Two ceiling fans are visible, providing airflow. A white sofa sits in the foreground, while a dining table with blue chairs and a daybed are arranged in the back area, creating a welcoming environment.
Apartment in Georgetown
5 out of 5 average rating, 36 reviews

Private Pondside Guest Suite

This peaceful guest suite is a full private studio apartment connected to our home with a private entrance-perfect for families, boaters, hunters, or those traveling for work. Parking on the premises is available for boats, trailers, and similar vehicles. We also offer charging for your boat battery-just let us know in advance so we can accommodate your needs. Your private getaway awaits!

Popular amenities for North Santee River vacation rentals