Guesthouse vacation rentals in National City

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Top-rated guesthouse rentals in National City

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Top guest favorite

A curving staircase is visible, flanked by white walls and adorned with vibrant blue tiles. Handrails provide support along the ascent, leading to a bright upper space. A potted plant enhances the serene ambiance at the top of the stairs.

Guesthouse in Mission Hills

5 out of 5 average rating, 216 reviews

Santorini-Inspired Cottage w/ Hot Tub + Views

*CHECK OUT OUR OTHER AIRBNB* Travel 16 steps up a Greek-inspired curving stairway with 2-story high walls to your tucked-away cottage built into the hillside villa of Alta Colina. With spectacular views, step onto the balcony to watch planes take off & boats sail around the harbor. End the night in front of your secluded back patio fireplace or climb the steps of your spiral staircase to the rooftop Jacuzzi. European-inspired design & details, it'll be hard to believe you’re still in San Diego!

Top guest favorite

Guesthouse in Spring Valley

4.99 out of 5 average rating, 388 reviews

Views• Outdoor Cinema•SoakTub +Zoo pkg add-on

City skyline & sunset views from this spacious & bright 600 sq ft private cottage—just a short drive outside the city, in the foothills of San Diego. Located on a gated estate overlooking 30 acres of canyonland, it features a cozy Queen bed, 50” Smart TV, Wi-Fi, kitchen, A/C & heat. Unwind in the outdoor hot soaking tub, catch a movie under the stars, and spot wild peacocks roaming the grounds - a perfect retreat for those wanting a special getaway on a very unique property overlooking the city!

Superhost

The modern kitchen features sleek white cabinetry and stainless steel appliances, complemented by a cozy seating area with a light-colored sofa adorned with decorative pillows. A round dining table surrounded by woven chairs sits on a textured area rug, enhancing the inviting atmosphere.

Guesthouse in Chula Vista

4.94 out of 5 average rating, 154 reviews

New! Beautiful Private Casita- King Bed & Office

Relax in this welcoming brand new casita featuring: ✓ Private side entrance with a keypad ✓ Modern kitchen fully equipped with cooking essentials ✓ Stocked coffee/tea bar with locally roasted coffee ✓ 1 bedroom with a comfy King size bed and smart TV ✓ 1 bath with essentials ✓ Separate office space, including monitor, keyboard, & fast internet, perfect for remote workers! ✓ In-unit washer/dryer, pods & dryer sheets provided ✓ Cozy outdoor living space ✓ Parking for 1 vehicle in the driveway

Top guest favorite

A cozy bedroom is highlighted by a spacious bed adorned with a bright yellow knit blanket. Framed photographs of palm trees and cityscapes decorate the walls, while bedside lamps provide soft illumination on either side of the bed.

Guesthouse in San Diego

4.94 out of 5 average rating, 179 reviews

Clean Cozy Private Guesthouse - Central San Diego

Centrally located, this cozy spot is professionally cleaned, well maintained & managed by a responsive host. Safe & secure it’s close to urban centers yet discretely nestled in a residential neighborhood, within 15 minutes to: The airport Petco Park SD Convention Center the Gas Lamp District SD Zoo Balboa Park Seaport Village beaches, major freeways & much more. Keyless entry for self-check, well-lit entry, generously-sized private, fenced yard, washer/dryer & RO water filter with faucet.

Superhost

A spacious sleeping area features a queen bed with a patterned throw blanket. Natural light enters through sliding glass doors that lead to the fenced yard. A modern entertainment center displays a flat-screen TV, while a ceiling fan enhances air circulation.

Guesthouse in National City

4.86 out of 5 average rating, 161 reviews

Private Pet-Friendly Studio w/Parking Near Gaslamp

Escape to this cozy, private back-studio, perfect for couples! Located just 4 miles from San Diego’s lively Gaslamp District, this studio offers a peaceful retreat in a safe neighborhood. Enjoy hassle-free parking and a fenced space with a private entrance through the side gate—no face-to-face contact. Fenced yard perfect for pets to play safely, plus nearby dog-friendly beach. Whether you’re here to explore downtown, relax in comfort, or visit Coronado, this studio is your ideal getaway!

Superhost

The bathroom features a modern design with double sinks set within a marble countertop. Two round mirrors reflect the sleek fixtures. A decorative box holds tissues, while a wall-mounted towel rack and a shower curtain can be seen in the background.

Guesthouse in Chula Vista

4.86 out of 5 average rating, 106 reviews

King Bed Studio in Chula Vista

Prime location in Chula Vista! Less than 2 miles away from the Gaylord Pacific Resort (10 min drive). Just a 20 min drive to most San Diego hot spots. Private studio with very comfortable king bed. Queen air mattress also available in unit. Modern bathroom with double-sink, standing shower, marble tile countertops. Spacious layout, a dedicated workstation and fast wifi. Prep your morning coffee and simple breakfast in the kitchenette. The mini fridge can store your favorite drinks.

Top guest favorite

An outdoor dining area features a large wooden table set with decorative dishes and neatly folded napkins. An umbrella provides shade above the table. Surrounding greenery and hanging hammocks create a tranquil atmosphere, while a pergola frames the space, enhancing the inviting outdoor setting.

Guesthouse in San Diego

4.96 out of 5 average rating, 385 reviews

Betty- Guesthouse near CBX & San Ysidro border

This comfy studio located in San Diego is the perfect spot for a quiet & cozy weekend retreat. Inside is bright & inviting with stylish spacious studio, private entrance from side gate, private patio with bbq & hanging hammocks; driveway parking spot & plenty of street parking! The view from the patio is very relaxing, making it the perfect weekend get away. Centrally located in a quiet & peaceful area within 5 minutes away from Plaza Las Americas & 10 minutes away from the CBX.

Guest favorite

An outdoor seating area features a covered gazebo with warm lighting, creating a welcoming ambiance. Surrounding the space are well-maintained grassy areas and neatly arranged stone pathways. Palm trees add a tropical touch against a backdrop of evening clouds and distant city lights.

Guesthouse in National City

4.95 out of 5 average rating, 185 reviews

Trendy 1 BR Guesthouse. Great views, no chores.

This is a beautiful 1 bedroom guest house with a full-size bed and full-size sofa bed. It is close to everything, making it easy to plan your visit. AirPort, Downtown, Coronado, Balboa Park, local beaches, Mexico, and Navy bases are just a few minutes' drive. Private on-site parking. Charge your EV on site. 110v or 220V Don't waste precious time on charging stations. Public transportation as well as plenty of shopping and restaurants within walking distance.

Top guest favorite

The poolside area features a well-maintained saltwater pool reflecting the colors of the sunset. Comfortable seating arrangements, including lounge chairs and a cozy fire pit, are visible. Large umbrellas provide shade, and lush greenery adds to the serene ambiance.

Guesthouse in Lake Murray

4.96 out of 5 average rating, 128 reviews

Vacation Paradise-Heated Pool+Hot Tub+FirePit+EV

This is the perfect Guest House with a salted & heated pool & hot tub. We are located in a super quiet & very safe neighborhood in beautiful San Diego, 15 minutes drive to Downtown, La Jolla, Beaches, Zoo, Sea World & Convention Center. Hike next door at Mission Trails & Lake Murray. Smart TV, wifi, two zone AC, full kitchen, W/D combo and top quality finishes await you inside. Everything you need for memorable vacation! No smoking or vaping on the property.

Top guest favorite

A private patio area is presented with a round dining table and four chairs, shaded by a large umbrella. Lush greenery surrounds the space, and sunlight filters through, creating a serene outdoor setting ideal for relaxation or dining.

Guesthouse in San Diego

4.97 out of 5 average rating, 128 reviews

SDSU Central Cozy Casita | Fast Wi-Fi | Walkable

Welcome to our cozy and stylish 500 sq. ft. one-bedroom Casita, tucked away in a quiet corner of our lot in the College Area of San Diego. With a private entrance and your own secluded patio, it’s the perfect little retreat whether you're visiting SDSU, exploring the city, or relaxing at the beach. 20 minute walk to SDSU Less than a 20 minute drive to the beach, airport, downtown, and the zoo!

Top guest favorite

A spacious bedroom features a large king size bed with a textured blanket, complemented by a nightstand and a decorative lamp. Sliding glass doors open to a deck, allowing natural light to fill the room. A flat-screen TV and a desk are visible in the background.

Guesthouse in Normal Heights

4.98 out of 5 average rating, 443 reviews

Mountain View Retreat in Gated Estate (Hot Tub)

Perched above a canyon with spectacular panoramic mountain views, this private guest house is a secluded retreat in one of San Diego’s most eclectic and desirable neighborhoods less than 6 miles from the Downtown San Diego airport. Enjoy a fully equipped kitchen, luxe king size bed and dual sliding glass doors that open to an expansive deck with patio seating, private hot tub and BBQ area.

Guest favorite

A spacious living area features light brown walls and hardwood flooring. A mounted television is displayed on one wall, accompanied by a small coffee table. A dining table with wooden chairs is situated near a window, which is dressed in sheer curtains allowing natural light to filter in.

Guesthouse in National City

4.87 out of 5 average rating, 226 reviews

Open concept Guesthouse w/private entrance

Welcome Travelers! We’re thrilled to host fellow Airbnb guests, especially those who love to travel as much as we do. My husband and I have had amazing experiences with Airbnb around the world, and now we're excited to share the beauty of San Diego with you! A few things to note: We live on the property in a completely separate unit with our dog and five chickens.