Guesthouse vacation rentals in National City

The exterior of a historic stone cottage showcases a rounded structure with large, circular windows. Native plants and decorative rocks surround the entrance, highlighting the natural landscape. The name 'Anna' is displayed on a rustic wooden sign, further enhancing the cottage's character.

4.91 out of 5 average rating, 477 reviews

Anna's Historic Stone Cottage w/panoramic View!

Welcome to Anna's Historic Stone Cottage! The 110 year old cottage has been transformed into the perfect combination of romantic and rustic for a dream-worthy getaway. The 280sq ft cottage features stunning, panoramic views of the San Diego skyline while offering rooftop seating for sunrise and sunset viewing. The Cottage is conveniently located 20 minutes from the world famous San Diego zoo and most other must-see, tourist spots. Amenities for special occasions offered too. Check out our menu!

Superhost

The living area features a grey sofa complemented by two pink chairs arranged around a low coffee table. An ornate area rug anchors the space, while framed botanical art adorns the wall. A large mirror reflects the light from stylish floor lamps and greenery.

4.93 out of 5 average rating, 248 reviews

Farm Vibe near City with Friendly Goats & Big Deck

Charming home has spacious bedroom (king bed), full bath (tub/shower), living/dining area and stocked kitchen all with stylish touches. Relax and lounge on your back deck while saying hello to the friendly goats. Your lodging is nearby the city where you can have a touch of countryside as well as modern amenities throughout with keyless entry, WiFi and Smart TV (W/D also available). It's a perfect space for a couple, small family or group of friends looking for a bit of it all next to it all!

A private patio space surrounded by lush greenery features seating areas with wooden chairs and potted plants. Soft lighting is provided by outdoor string lights, and a cozy rug adds warmth. In the distance, a shaded area with an umbrella can be seen, enhancing the tranquil setting.

4.96 out of 5 average rating, 282 reviews

Sunny garden casita in vibrant North Park

Enjoy peaceful, sunny San Diego days as palms sway above this private garden retreat tucked behind a 1925 Craftsman. Designed with a love of nature and simple beauty, the guest house opens onto lush greenery and dappled light — a calm, creative hideaway in the heart of one of San Diego’s most charming neighborhoods. Just a short stroll brings you to great restaurants, world-class breweries, and cozy coffee shops, while Balboa Park, the Zoo, the beaches, and downtown are all only minutes away.

Guesthouse in Golden Hill

A charming exterior of a boutique guesthouse is presented, featuring a vibrant yellow door and large windows. Lush greenery with various plants and flowers adorns the landscape, while a crafted stone pathway leads to the entrance. A warm, inviting atmosphere is conveyed through well-maintained landscaping.

The Golden Hill mosaic "casita"

This is a boutique guesthouse that is part of a 1913 duplex which has been extensively remodeled, and yet maintains its essence in historic Golden Hill. It is a solar-powered 1-bedroom 1-bathroom featuring custom Mexican furniture, french doors, a view of the San Diego Skyline, and a private patio area. Feel the cool breeze on top of Golden hill, a centrally located up and coming neighborhood with lots of walkable destinations. The home is exquisitely decorated with custom Chilean mosaics.

4.87 out of 5 average rating, 568 reviews

The poolside area features a well-maintained saltwater pool reflecting the colors of the sunset. Comfortable seating arrangements, including lounge chairs and a cozy fire pit, are visible. Large umbrellas provide shade, and lush greenery adds to the serene ambiance.

4.96 out of 5 average rating, 181 reviews

Vacation Paradise-Heated Pool+Hot Tub+FirePit+EV

Welcome to your personal resort! This is your private Guest House with a salt & heated pool + hot tub. Located in a very quiet & safe neighborhood in beautiful San Diego. Drive 15 minutes to the beach, downtown, La Jolla, Zoo, stadiums, Sea World, Convention Center + more. Hike next door at Cowell Mountain or Lake Murray. Smart TV, wifi, two zone AC, full kitchen, W/D combo, top quality finishes & furniture. Everything you need for memorable vacation! No smoking or vaping on the property.

Guesthouse in Lemon Grove

A modern kitchen is showcased with sleek white cabinetry and stainless steel appliances. A spacious island features four high stools arranged for seating, while a large window allows natural light to illuminate the area. Cooking essentials and a coffee maker are visible on the countertop.

STUNNING Casita with a View!!

If you’re reading this, we want to thank you for showing interest in our charming Casita! 🏡 Recently renovated with couples in mind, it’s a cozy, relaxing space perfect for your getaway. Features include: • 🚗 On-property parking • 🍳 Fully furnished kitchen with all appliances • 🧺 Washer and dryer in-home • 💻 High-speed internet • ✨ Clean, modern, comfortable space • 🌄 Breathtaking mountain and valley views We’d love to host you and make your San Diego stay truly memorable!

4.89 out of 5 average rating, 247 reviews

An outdoor dining area features a large wooden table set with decorative dishes and neatly folded napkins. An umbrella provides shade above the table. Surrounding greenery and hanging hammocks create a tranquil atmosphere, while a pergola frames the space, enhancing the inviting outdoor setting.

4.96 out of 5 average rating, 437 reviews

Betty- Guesthouse near CBX & San Ysidro border

This comfy studio located in San Diego is the perfect spot for a quiet & cozy weekend retreat. Inside is bright & inviting with stylish spacious studio, private entrance from side gate, private patio with bbq & hanging hammocks; driveway parking spot & plenty of street parking! The view from the patio is very relaxing, making it the perfect weekend get away. Centrally located in a quiet & peaceful area within 5 minutes away from Plaza Las Americas & 10 minutes away from the CBX.

The exterior of a renovated guesthouse is presented, featuring a white stucco facade with decorative tiles along the steps. A green door, large windows, and a charming walkway leading to the stairs enhance the inviting appearance of the property.

4.99 out of 5 average rating, 199 reviews

Carrie’s North Park Casita, in Heart of San Diego

Fully renovated stand-alone guesthouse in North Park, consistently voted one of the coolest neighborhoods in the US. Just a few blocks from all the action at 30th and University, but tucked away in a quiet, historically designated residential neighborhood. Walk to Balboa Park or The World Famous San Diego Zoo. Get to Downtown San Diego, San Diego International Airport, Old Town, Little Italy, Coronado, La Jolla, Sea World, multiple beaches & so much more in under 15 minutes.

Guesthouse in National City

An outdoor seating area features a covered gazebo with warm lighting, creating a welcoming ambiance. Surrounding the space are well-maintained grassy areas and neatly arranged stone pathways. Palm trees add a tropical touch against a backdrop of evening clouds and distant city lights.

Trendy 1 BR Guesthouse. Great views, no chores.

This is a beautiful 1 bedroom guest house with a new Queen size bed (4/13/2026)and full-size sofa bed. It is close to everything, making it easy to plan your visit. AirPort, Downtown, Coronado, Balboa Park, local beaches, Mexico, and Navy bases are just a few minutes' drive. Private on-site parking. Charge your EV on site. 110v or 220V Don't waste precious time on charging stations. Public transportation as well as plenty of shopping and restaurants within walking distance.

4.95 out of 5 average rating, 249 reviews

Guesthouse in National City

Private Pet-Friendly Studio w/Fenced Yard +Parking

Private, pet-friendly studio perfect for couples or travelers with a dog. Enjoy easy parking, a private side-gate entrance, self check-in, and a fenced yard for pets to play safely. The studio is fully separate from the main house for added privacy. Located just 4 miles from the Gaslamp District, with easy access to downtown, Coronado, nearby dog-friendly beaches, restaurants, and bars, it’s a quiet and convenient home base for your San Diego stay.

4.87 out of 5 average rating, 216 reviews

Guesthouse in Golden Hill

A bright bedroom is furnished with a gold metal bed, adorned with white linens and decorative pillows. Large windows allow natural light to fill the room, and a green plant adds a touch of nature. A comfortable chair and a small bedside table complete the decor.

*BEAUTIFUL* Sunny Home in Golden Hill

Bright & Sunny Home Guest house with private entrance and deck. Lots of great restaurants and shops nearby. Located on a quiet street with a nice kitchen, A/C, heat, deck, king bed, and laundry. New washer and dryer. **PRICING TRANSPARENCY** This platform has changed the way that guests see pricing and fees. My normal rate is $130/night. This platform now adds their fees of 15.5% onto the nightly price so it looks much more expensive.

4.94 out of 5 average rating, 436 reviews

Guesthouse in National City

Open concept Guesthouse w/private entrance

Welcome Travelers! We’re thrilled to host fellow Airbnb guests, especially those who love to travel as much as we do. My husband and I have had amazing experiences with Airbnb around the world, and now we're excited to share the beauty of San Diego with you! A few things to note: We live on the property in a completely separate unit with our dog and five chickens.

4.87 out of 5 average rating, 263 reviews

Popular amenities for National City guesthouse rentals

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

Family-friendly guest house rentals

4.9 out of 5 average rating, 675 reviews

Guesthouse in South Park

Private South Park Bungalow - Yard & Parking

Superhost

A clean, modern studio features a spacious bed with light blue and white striped bedding. A kitchenette with a microwave and electric burners is equipped with essential utensils. Large sliding glass doors provide access to a private deck, allowing natural light to fill the room.

Guesthouse in Bonita

Private Modern Studio with Ocean View

4.82 out of 5 average rating, 244 reviews

Guesthouse in Lemon Grove

A cozy living area features a dark sectional sofa adorned with various cushions. A round coffee table is placed in front, set on a plush area rug. Two windows with patterned curtains allow natural light to enter, highlighting the warm tones of the space.

Adorable Lemon Grove Studio

4.97 out of 5 average rating, 224 reviews

5.0 out of 5 average rating, 210 reviews

A bright living area is characterized by large windows that invite natural light and provide views of greenery outside. A wall-mounted TV is positioned opposite a comfortable sofa, while a colorful dining chair adds a playful touch to the space.

Guesthouse in Del Cerro

The Happy Family * 2 playhouses & baby gear

A cozy sleeping area is presented with a spacious bed covered in light linens. Beside it, a nightstand with a lamp provides soft lighting. A small round table with a plant adds a touch of greenery, and natural light enters through bright windows framed by soft curtains.

4.87 out of 5 average rating, 222 reviews

Downtown Cottage Walkable to Gaslamp & Petco Park

Two red Adirondack chairs are positioned under a covered patio, facing a serene backyard with a pool. Lush greenery surrounds the area, creating a tranquil atmosphere. A BBQ room and various seating arrangements are visible beyond the pool, enhancing the outdoor retreat experience.

4.99 out of 5 average rating, 185 reviews

Private 1 BR Paradise Retreat

Guesthouse in Golden Hill

A view of downtown San Diego is captured from the balcony, framed by lush palm trees and residential rooftops. City skyscrapers rise in the distance, under a clear blue sky, creating a vibrant urban landscape complemented by greenery.

Golden Hill House, Gorgeous Skyline, Private Patio

4.89 out of 5 average rating, 487 reviews

A cozy interior features wooden paneling and a comfortable grey sofa with a decorative pillow. A small kitchenette is equipped with cabinets and appliances. A dining table is set for two, and a guitar is displayed on the wall, adding a touch of creativity to the space.

4.93 out of 5 average rating, 234 reviews

La Cabana

Guest house rentals with a patio

Guesthouse in Mission Hills

Mission Hills Studio with Office - Great Location

4.92 out of 5 average rating, 101 reviews

Superhost

The bathroom features a modern design with a glass-enclosed shower and a spacious vanity. A dark cabinet complements the white walls, while a bright yellow rug adds a pop of color to the black hexagonal tile floor. Ample lighting is provided above the mirror.

Guesthouse in Spring Valley

*Look*Secluded/studio/getaway w/ Sunset View+patio

4.8 out of 5 average rating, 100 reviews

Guesthouse in Mission Hills

The open studio loft features a spacious queen bed draped with light fabric. A small blue sofa with decorative cushions sits opposite a wooden coffee table. Natural light streams in through a well-placed window, illuminating the soft carpet and simple decor.

Mission Hills: Private Studio • Walk to Hillcrest

4.98 out of 5 average rating, 218 reviews

Guesthouse in Spring Valley

The tiny cabin is illuminated by soft lighting, showcasing its wooden exterior and welcoming design. Surrounding cacti and plants enhance the natural setting, while steps lead up to a private deck. The evening sky provides a serene backdrop, highlighting the cabin's cozy atmosphere.

Loft Cabin•SoakTub•FirePit• Cinema•View+Zoo add-on

4.98 out of 5 average rating, 233 reviews

Guesthouse in Normal Heights

Cozy Casita in Heart of Normal Heights

4.9 out of 5 average rating, 102 reviews

4.98 out of 5 average rating, 138 reviews

Guesthouse in Bonita

Adorable 1- bedroom guesthouse/Casita

A private patio area is presented with a round dining table and four chairs, shaded by a large umbrella. Lush greenery surrounds the space, and sunlight filters through, creating a serene outdoor setting ideal for relaxation or dining.

4.96 out of 5 average rating, 174 reviews

SDSU Central Cozy Casita | Fast Wi-Fi | Walkable

A modern kitchen is visible, featuring sleek black cabinets and white countertops. Stainless steel appliances, including a gas stove, are present. A small dining area with a black table and checkered tablecloth complements a cozy seating area, illuminated by natural light from large windows.

4.93 out of 5 average rating, 414 reviews

La Mesa Suite

Guest house rentals with a washer and dryer

A private guest home features a modern exterior with corrugated metal siding and a vibrant red door. A wooden deck is visible, surrounded by greenery, providing an inviting entrance. Two small windows are positioned on either side of the door, offering natural light.

4.99 out of 5 average rating, 326 reviews

Hawks nest

5.0 out of 5 average rating, 581 reviews

A tranquil koi pond is nestled within a landscaped garden, featuring several colorful koi fish swimming gracefully near the surface. Rocks and plants frame the pond, while a small waterfall cascades gently into the water, creating a soothing ambiance.

Guesthouse in Hillcrest

Waterhaven - A Pondside Oasis

Guesthouse in Normal Heights

The “OUT” House: Artist’s Loft/Studio

4.94 out of 5 average rating, 175 reviews

The bedroom features a upholstered headboard and is accented by warm bedside lamps. A large photograph of a pier over water hangs above the bed, while blue and white decorative pillows add contrasting color. A cozy quilt covers the spacious bed.

4.94 out of 5 average rating, 328 reviews

Enjoy North Park at Comfy & Chic Bungalow Retreat

4.96 out of 5 average rating, 409 reviews

A modern living area features a spacious sectional sofa with decorative pillows, accompanied by a marble top coffee table. A bright kitchenette is visible, equipped with stainless steel appliances. Natural light streams through multiple windows, leading to an outdoor space with a view.

Guesthouse in Bay Park

Private Guesthouse with Bay View Deck

A bright living area is visible, featuring a mix of modern furnishings including a cozy sofa, a smart TV, and a circular dining table with wooden chairs. Large windows allow natural light to fill the space, highlighting the warm wooden flooring and inviting decor.

4.98 out of 5 average rating, 133 reviews

East Watch- a private getaway

A sunset is captured shining through trees, casting rays of light over the guest house. The structure features large windows, allowing natural light to fill the space. Palm trees and distant silhouettes of buildings are visible against the colorful sky.

4.95 out of 5 average rating, 662 reviews

Early 1900's Carriage House w/Views

A spacious living area is presented with a gray sectional sofa adorned with colorful throw pillows. A round coffee table sits on a textured area rug. The kitchen features modern fixtures, while natural light fills the room through windows with a view of the patio.