Guesthouse vacation rentals in National City

Find and book unique guesthouse rentals on Airbnb

Top-rated guesthouse rentals in National City

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Guest favorite

Guesthouse in San Diego

4.97 out of 5 average rating, 292 reviews

Private Guest House with a View

A charming, detached guest house located centrally in San Diego, Ca. Guest house is located on a hill with views of the canyon. Get full access to your own kitchen with coffee & tea amenities. Wifi access. Smart TV access to Netflix, Prime Video, Disney+, Hulu, etc.. Comfortable queen bed with a full size sofa pullout bed that can accommodate up to 4 guests. Clean and spacious backyard that you can relax and unwind in. 80’ leveled driveway 12’ wide is big enough to accommodate any RV.

Aug 8 – 15

G$30,642 GYD per night

Guest favorite

Guesthouse in San Diego

4.97 out of 5 average rating, 283 reviews

Betty- Guesthouse near CBX & San Ysidro border

This comfy studio located in San Diego is the perfect spot for a quiet & cozy weekend retreat. Inside is bright & inviting with stylish spacious studio, private entrance from side gate, private patio with bbq & hanging hammocks; driveway parking spot & plenty of street parking! The view from the patio is very relaxing, making it the perfect weekend get away. Centrally located in a quiet & peaceful area within 5 minutes away from Plaza Las Americas & 10 minutes away from the CBX.

Aug 28 – Sep 4

G$26,815 GYD per night

Superhost

Guesthouse in National City

4.82 out of 5 average rating, 164 reviews

Open concept Guesthouse w/private entrance

Hello travelers! My husband and I have done a bit of traveling and have used Airbnb around the world. We have had wonderful experiences around the world and are thrilled to be able to host our fellow Airbnb family. We are excited help you explore San Diego like a local. We would like to address Covid 19 and assure our guests that we have enhanced our already rigorous cleaning policy. PLEASE BE ADVISED We live on the on the 3 unit property w/our dog & a permanent tenant.

Oct 1 – 8

G$25,162 GYD per night

Guest favorite

Guesthouse in El Cajon

4.98 out of 5 average rating, 191 reviews

Fletcher Hills - modern 1 BR.Easy, no step access.

** 48 hours between check-ins. Thorough cleaning and sanitizing.. Four night minimum stay. Dogs ONLY are welcomed on a case by case basis. They must be house trained and are not permitted on any furniture. If you instant book, you must contact me about your pet within 24 hours. Smoking is permitted in the outside areas - patio, gazebo, yard. Easy freeway access helps any commute to downtown and area attractions. Having your own vehicle is the best way to get around..

Sep 24 – Oct 1

G$24,558 GYD per night

Guest favorite

Guesthouse in San Diego

4.98 out of 5 average rating, 185 reviews

North Park Garden Retreat Casita

Nestled between the urban neighborhoods of North and South Park, our sanctuary within the heart of the city is surrounded by a secret garden that gives the impression of a tropical oasis. The private casita is tucked in the backyard of the Host’s home and has french doors which open to the lush greenery of the garden. Whether vacationing, traveling for work, or looking for an ideal space for relaxation and renewal, this is the perfect place to enjoy your San Diego stay.

Oct 22 – 29

G$23,104 GYD per night

Guest favorite

Guesthouse in San Diego

4.99 out of 5 average rating, 109 reviews

Modern Guest House with Patio, Parking, & Laundry

We may not be on the beach, but we're pretty darn close! Located in the Encanto neighborhood of San Diego proper, our Guest House is an ideal stay for vacationers, workcationers, and those who want to try the local life! While a car is mandatory to see all that San Diego has to offer, we are very close to a trolly that can get you downtown and adjacent areas. Please reach out to us if you have any questions, and we will do our best to accomodate you!

Oct 20 – 27

G$29,756 GYD per night

Guest favorite

Guesthouse in San Diego

4.86 out of 5 average rating, 125 reviews

Private, beautiful 1-bedroom 2 story guest house

Relax in this 1-bedroom 2 story spacious and cozy guesthouse. With private patio, private kitchen, dinning area and livingroom downstairs. Sofa/futon bed downstairs. Bedroom, walk-in closet and full bathroom upstairs. 2 TVs for your enjoyment with streaming services. One downstairs and one upstairs. Close to freeways, shopping, restaurants and coffee shops. Cooking utensils, coffee (provided) and some spices. All smoking free environment.

Sep 28 – Oct 5

G$22,335 GYD per night

Guest favorite

Guesthouse in San Diego

4.97 out of 5 average rating, 183 reviews

Fresh, hip and cozy private North Park guest house

Enjoy peaceful sunny San Diego days listening to the palm trees sway in this private backyard garden retreat set behind a 1925 California craftsman. The guest house is tucked away in a quiet quintessential Southern California neighborhood while only being a short and easy walk to amazing restaurants, world class breweries and cozy coffee shops. Balboa Park, the San Diego Zoo, beaches and downtown are all a few minutes drive away.

Apr 24 – May 1

G$27,240 GYD per night

Guest favorite

Guesthouse in San Diego

4.95 out of 5 average rating, 363 reviews

The South Park Tiki Bungalow. #the_tiki_bungalow

Escape to an enchanted tiki hideaway in a walkable, historic neighborhood! The South Park Tiki Bungalow is a perfect getaway for two! Full kitchen and bath, one bedroom with a full size bed. Easy street parking leads you to a private entrance at the rear of the property. A gate with coded entry opens up to your very own bamboo enclosed patio protected by numerous hand carved Tikis. Thanks and we look forward to hearing from you!

Sep 15 – 22

G$26,422 GYD per night

Guest favorite

Guesthouse in San Diego

4.96 out of 5 average rating, 125 reviews

Brand New Modern North Park View Apartment

This brand new North Park apartment is the perfect place to enjoy San Diego. The home is located on a quiet street in close proximity to Balboa Park, the San Diego Zoo, Downtown, Sea World, Old Town, Coronado Island, Seaport Village, and the airport. It is in walking distance to a number of renown restaurants, coffee shops, and breweries. Beautiful sunset views allow you to relax after a long day of taking in the city.

Jan 10 – 17

G$26,080 GYD per night

Guest favorite

Guesthouse in Chula Vista

4.95 out of 5 average rating, 476 reviews

Private Casita in Great Eastlake Neighborhood

This room is a "casita" (seperate living space) away from the house. It has a private entrance with a cypher lock on the door. The room has new carpet, new tile, and queen size bed. The Eastlake neighborhood is very safe and very quiet. We are located about 20 mins from the beach, downtown San Diego, and San Diego international airport. This location is only 2 miles from the Otay Ranch Mall.

Sep 16 – 23

G$21,096 GYD per night

Guest favorite

Guesthouse in San Diego

4.9 out of 5 average rating, 193 reviews

STUNNING Casita with a View!!

Recently renovated two story Casita located just 20 minutes away from Downtown San Diego. Experience the crafty layout of this 500 square foot Casita. If you’re looking to unwind and refresh, then this quiet and cozy home at the end of the cul-de-sac is the right choice for you. Enjoy beautiful valley views from your living room. Perfect for a peaceful and relaxing getaway or extended stay.

Oct 21 – 28

G$26,624 GYD per night