Vacation rentals in Muscatine

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Top-rated vacation rentals in Muscatine

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
A historic four-bedroom home is captured with tall trees framing the exterior, set against a clear blue sky. The architectural features include a prominent turret and multiple windows, reflecting the home's charm. A snow-dusted yard leads to a view of the nearby Mississippi River.
Home in Muscatine
4.96 out of 5 average rating, 139 reviews

Historic West Hill Retreat

Beautiful historic 4 bedroom, 4 bath home within walking distance to shopping, bars/restaurants and all that downtown Muscatine has to offer. Enjoy sweeping views of the Mississippi River from several vantage points in and outside this home. The 3000 sf interior offers many places to gather and relax. Two of the bedrooms have on suite full baths. The other two bedrooms share a full bath. Additional amenities include, fully equipped kitchen, laundry, games, grill, outdoor entertainment area.

Top guest favorite
The cottage's exterior features a welcoming facade adorned with colorful flowers and greenery. A spacious deck is bordered by stone pathways, while large windows allow natural light to flood the living spaces. Mature trees provide shade in the surrounding area.
Cottage in Le Claire
4.97 out of 5 average rating, 524 reviews

The Cottage. River views, event & dog friendly!

Make yourself at home in a fully renovated cottage built in 1910. This cottage sits on a steep hill above the original Homestead of Buffalo Bill Cody. Enjoy a beautiful Park directly behind you, full river views in front of you. BEFORE BOOKING PLEASE NOTE: *The cottage is on a steep hill. *You will hear trains. LeClaire is a river & train town. 🚂🌊 *This is a wooded property, There will be sticks, leaves and bugs. 🌿🐞 *There are MANY steps inside and outside, as it's built into a hill.

Superhost
Apartment in Davenport
4.64 out of 5 average rating, 11 reviews

Sweet Stay In The Quad Cities

Our cozy first floor apartment features a king bed, full kitchen and living room, perfect for your stay in Davenport. 📍Prime Location: 0.2 miles to St. Ambrose University College of Health & Human Services 3 min to Genesis West 5 min to Mississippi Valley Fairgrounds 10 min to Augustana College, Vibrant Arena, Downtown Davenport & Riverfront ⚠️Important: The home is on Marquette, a safe but busy street and in proximity to the hospital. Expect cars and ambulance sounds. Can be noisy.

Top guest favorite
An open living space is presented with textured brick walls and large windows allowing natural light to brighten the area. A dining table with white chairs sits in the foreground, while a plush sofa and a television are positioned in the seating area.
Loft in Williamsburg
4.98 out of 5 average rating, 116 reviews

1890 Lofts - Harvester | Historic Loft, King Beds

Step back in time in The Harvester, an airy and bright second-floor loft honoring William Deering and the Deering Harvester Company, which operated out of the first floor in the early 1900s. Perfect for families returning to the area, wedding groups, or travelers passing through on I-80, the loft features king beds, a spa-like bathroom, games, and a coffee station. Just minutes from Amana Colonies, Fireside Winery, Stone Creek Golf, and local dining, your ideal Iowa stopover starts here!

Guest favorite
The entrance to the cottage features a decorative door framed by colorful trim. A wooden porch is accessed by a set of steps, and the house displays intricate architectural details, including a ceiling fan and house number on the door. Sunlight casts shadows across the entrance.
Cottage in Rock Island
4.94 out of 5 average rating, 312 reviews

Carla's Cottage

This little cottage is a Rock Island Historic house. Nestled among the large Victorians, it was built in 1879 and housed various workers, from a blacksmith, to a wallpaper hanger! Located just blocks from the Mississippi River you can walk along a paved bike path with gorgeous views. In the evening enjoy the vibrant nightlife, with music and a dinner playhouse! This tiny historic cottage is great for a quick night, but perfect for class reunions, weddings and the John Deer Classic!

Top guest favorite
The exterior of the Milk House features a red structure with gray siding, adorned with a triangular window and a decorative sun motif. A small porch with a welcome sign opens to a gravel path lined with flower planters. A chair and table are set for outdoor relaxation.
Farm stay in Iowa City
4.98 out of 5 average rating, 397 reviews

The Milk House at Lucky Star Farm

The Milk House is a unique space located in the countryside, between Iowa City and Kalona. This 700 square foot home has ample parking and room for four adults. The house is well appointed with a full kitchen, two luxurious queen beds, wifi and a Smart TV. Guests are invited to explore our 20-acre working farm with lots of livestock and two friendly dogs. It's a perfect blend of rural living with the perks of beautiful Iowa City 15 minutes away. Come unwind at Lucky Star Farm!

Guest favorite
A view of the open-concept space highlights a kitchen area with a green countertop and a stove. The living area features light brown and tan upholstery on the seating, complemented by green carpet. A ceiling fan is visible along with warm lighting throughout the space.
Loft in Muscatine
4.95 out of 5 average rating, 240 reviews

The Emerald Loft Apartment

Stay in a Historic District Downtown loft! River views. Nearby park, playground, bike trails, boat ramps & marina. Shopping, live music, & restaurants. Private entry with 1,000 sqr ft of space, open concept, full kitchen, TV, laundry, private bath, literally right in middle of everything. Check in at Creations by Oz "Jewelry, Wine, & Unique Finds". Enjoy a glass of wine upon check-in. Come hungry. Photo comments provide dining options within steps of the Emerald Room.

Top guest favorite
A balcony offers a view of the Mississippi River, featuring flower boxes with colorful blooms along the railing. Two chairs are positioned for relaxation, overlooking a landscaped area and nearby road, with additional greenery visible along the riverbank.
Apartment in Muscatine
5 out of 5 average rating, 35 reviews

Beautiful Condo Downtown with River Views

3rd Floor Condo in the old Hotel Muscatine 100 plus years old just totally refurbished condo with a Beautiful Balcony with view of bridge and Mississippi River 2 bedrooms 1 full bed bedroom and 1 queen bed bedroom with both views of river and bridge and a 1/2 bath bath and full bath with soaking tub and rain shower, stackable washer and dryer, full kitchen fully stocked, desk area, beautiful patio with chairs over looking lit up bridge and river Adults Only 2 Night Minimum

Top guest favorite
A neatly landscaped home with a dark blue exterior is set amidst green grass and vibrant flower beds. The entryway features a welcoming red door framed by a decorative wreath. The walkway leads to a set of steps, enhancing the home's approachable charm.
Home in Bettendorf
4.92 out of 5 average rating, 165 reviews

Amazing updated 2 bedroom home 2 bath.

Your family will be close to everything when you stay at this centrally-located place. In the heart of Bettendorf. Close to interstates, shopping, Bettendorf Sports Complex, Village of East Davenport. Off street parking. Garage access if needed. Plenty of space two beds and bath on main level. Lower rec room has additional bath and sleeping accommodations. Quiet street. Fenced in back yard. Private deck. This house has everything for a short stay or long stay.

Top guest favorite
A rustic cabin with a red exterior is highlighted by the soft glow of the sun. A gravel pathway leads from the front to a spacious green yard, bordered by trees. The structure features a peaked roof and large windows that invite natural light.
Cabin in Blairstown
4.97 out of 5 average rating, 234 reviews

Private, pet friendly country cabin

Rustic decor cabin nestled in the iowa countryside. You will love the privacy and quiet nights! BBQ on the back deck or enjoy an evening by the firepit in the backyard (wood onsite). Evening walks offer some spectacular views of the beautiful Iowa country sunsets! Close to public hunting, golfing, and Benton County's Hannan Park for fishing or swimming. Located a half hour west of Cedar Rapids and 45 minutes from Iowa City for game days. Pets are welcome.

Top guest favorite
A living area features a light-colored sectional sofa accented with orange and blue pillows. Two accent chairs are positioned near a round ottoman. A round mirror hangs on the wall, and a dining area is visible in the background through a window.
Home in Bettendorf
4.99 out of 5 average rating, 109 reviews

Newly Renovated,Super Clean,3BR, Great Location

This newly renovated 3 bedroom Bettendorf ranch home is fully equipped and centrally located, with easy access to both sides of the Mississippi. Ready for your personal or business stay, this home features new furniture, kitchen, bath, and flooring throughout the main level. Relax and unwind while nestled in front of the 55" smart TV, or simply bring your own device and connect to fast fibre whole home wifi. Welcome to Bettendorf and the entire Quad Cities!

Top guest favorite
An open living space features a stone fireplace beside a kitchenette with granite countertops and a large island with seating. Aqua-colored bar stools surround the island, while a black leather sofa and wooden coffee table provide comfortable seating. Natural light fills the area, enhancing its inviting feel.
Guesthouse in Iowa City
4.98 out of 5 average rating, 280 reviews

River Street Suite

Enjoy the beautiful Iowa River and Peninsula Park Views, in this private and peaceful guest suite apartment with private outdoor entrance and driveway. Walk to the Carver-Hawkeye Arena, Kinnick Stadium, UI Medical Campus & Veterans Hospital. Located in a highly sought-after walkable location off the Iowa River Corridor Trail. Less than a mile away from Hancher Auditorium & UI Campus. A 5 min drive to downtown Iowa City, Iowa River Landing Coralville and I-80.

Popular amenities for Muscatine vacation rentals

When is the best time to visit Muscatine?

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Avg. priceG$28,834 GYDG$28,834 GYDG$28,834 GYDG$28,834 GYDG$29,252 GYDG$28,834 GYDG$30,506 GYDG$33,849 GYDG$37,401 GYDG$28,834 GYDG$28,834 GYDG$28,834 GYD
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Quick stats about vacation rentals in Muscatine

  • Total vacation rentals

    Explore 20 vacation rentals in Muscatine

  • Nightly prices starting at

    Muscatine vacation rentals start at G$16,715 GYD per night before taxes and fees

  • Verified guest reviews

    Over 780 verified reviews to help you choose

  • Family-friendly vacation rentals

    10 properties offer extra space & kid-friendly amenities

  • Wi-Fi availability

    20 of Muscatine vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Muscatine rentals

  • 4.8 Average rating

    Muscatine stays are highly rated by guests—averaging 4.8 out of 5!

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