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House vacation rentals in Mytilini

Find and book unique houses on Airbnb

Quick stats about house rentals in Mytilini

  • Total vacation rentals

    Explore 100 vacation rentals in Mytilini

  • Nightly prices starting at

    Mytilini vacation rentals start at G$4,176 GYD per night before taxes and fees

  • Verified guest reviews

    Over 2,200 verified reviews to help you choose

  • Family-friendly vacation rentals

    40 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 30 rentals that welcome pets

  • Rentals with dedicated workspaces

    30 properties have a dedicated workspace

  • Wi-Fi availability

    100 of Mytilini vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Mytilini rentals

  • 4.8 Average rating

    Mytilini stays are highly rated by guests—averaging 4.8 out of 5!

Top-rated house rentals in Mytilini

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Guest favorite
A newly built villa is shown beside a sandy beach, featuring blue shutters and a shaded outdoor seating area. A tree provides natural shade, with the crystal blue waters visible in the background, and distant mountains lining the horizon under a clear sky.
Home in Plomari
4.89 out of 5 average rating, 103 reviews

Floras Charming Waterfront Villa

Flora's charming waterfront villa is located in the centre of the traditional picturesque village of Melinda, situated 6 km west of the village of Plomari. Our villa is situated literally on the beach, which is known for its crystal blue waters. The newly built modern house is fully equipped with all conveniences, such as a modern kitchen, air condition units in all rooms, tv, wi-fi etc. The famous traditional greek taverna of Maria is right next door, where you can enjoy local delicacies all day. In Our quiet villa you will experience greek at its summer, watching the sunset.

Guest favorite
An elevated view of the living area displays a spacious layout with high ceilings and wooden beams. Large windows allow natural light to fill the room, where a contemporary sofa and stylish coffee table create a cozy seating area. Decorative elements add character to the wall.
Home in Plomari
4.92 out of 5 average rating, 25 reviews

Beautiful Plomari Cottage

Newly renovated, spacious and stylish house in a quiet street at the heart of Plomari is a perfect place for couples, groups and families of up to 6 people. It boasts an ultra-high ceiling with a lovely gallery. Fully equipped kitchen, dining area, bedroom and full bathroom on ground floor; additional bedroom, full bathroom, open space with a sofa-bed in the gallery. Amoudeli beach is a 250m stroll. Important note: for safety reasons, children under 12 years old are not allowed up at the gallery

Guest favorite
A terrace table is set with a traditional tea service, featuring a teapot and cups. The view overlooks the sandy beach and calm Aegean sea, with two sun loungers and an umbrella in the distance, framed by a backdrop of green sod and blue skies.
Home in Mistegna
5.0 out of 5 average rating, 7 reviews

Perfect Beachfront Location

Set right on the beach in Skala Mistegnon, Kyparissis Beach House offers direct access to the sea and beautiful views across the Aegean. Guests can relax on the terrace or enjoy the outdoor seating area just steps from the shore. This spacious holiday home includes two bedrooms, two bathrooms, a comfortable living room, and a fully equipped kitchen. Additional features include air conditioning, a private balcony, and WiFi throughout the property. Take it easy at this unique and tranquil getaway.

Top guest favorite
A dining table set on an outdoor terrace is arranged for a meal. Plates are placed beside crystal glasses, with a colorful spread of grapes, watermelon, and other fruits displayed on a platter. A glass pitcher and bottles, including a wine bottle, complete the inviting setting.
Home in Mytilini
4.98 out of 5 average rating, 98 reviews

Aegean View Resort # The House

Tranquillity, relax and comfort best describe this house set in absolute nature in a peaceful suburb, only a few minutes away from the heart of the Mitilini. The property featuring stunning architectural details that provides guests with a high level of comfort and style but it can also be your base for exploring the rest of the beautiful and big island.It is perfect for families, couples or a group of friends looking for spacious areas, large terraces, comfort and privacy.

Top guest favorite
A spacious sleeping area is highlighted by a relaxing atmosphere. A large, vintage bathtub is positioned nearby, and a small table with fresh flowers adds a touch of color. Natural light filters in, enhancing the room's inviting design.
Home in Mytilini
4.99 out of 5 average rating, 74 reviews

Παραδοσιακό σπίτι της Ιωάννας στο κέντρο 140 τ.μ.

Παραδοσιακό κτήριο, χτισμένο το 1880, στο ιστορικό κέντρο της πόλης. Ανακαινισμενο το 2008. Απευθυνεται στους λατρεις του αυθεντικού, τις αντικών και της τέχνης! Ιδανικό για ρομαντικές διακοπές (επιλογή των honeymooners). Προσφέρει άνετη διαμονή σε οικογένειες με μικρά παιδιά και μωρά! Σε απόσταση 5 λεπτών με τα πόδια από το λιμάνι και την παραλία, τα καφέ, τα εστιατόρια, τα μπαρ, καθώς τα περισσότερα αξιοθέατα της Μυτιλήνης! Παιδιά κάτω των 12 ετών διαμένουν δωρεάν!

Top guest favorite
The tranquil night view captures three modern villas framed by lush greenery. A private pool is illuminated in soft blue, reflecting the clear sky. Warm light glows from the villas, highlighting their welcoming architecture against the serene backdrop.
Home in Mytilini
5.0 out of 5 average rating, 20 reviews

Pierres Blanches Recidences 2

Ανακαλύψτε την απόλυτη εμπειρία διαμονής 1,5 χιλιόμετρο απο το κέντρο της πόλης της Μυτιλήνη. Με κομψό σχεδιασμό και μοντέρνες ανέσεις, οι τρεις αυτόνομες μονοκατοικίες μας, των 120 τ.μ. η καθεμία, σας προσκαλούν να απολαύσετε την ηρεμία και την ομορφιά του νησιού. Κάθε βίλλα διαθέτε τρία άνετα υπνοδωμάτια, δύο μπάνια, ευρύχωρο σαλόνι, σοφίτα, πλήρως εξοπλισμένη κουζίνα και ιδιωτική πισίνα για να δροσιστείτε και να απολαύστε τον ήλιο στην άνεση της δικής σας πισίνας.

Guest favorite
A serene cottage sits by the water's edge, framed by lush greenery and a distant hill. The home showcases a traditional design with a tiled roof and multiple windows, inviting bright natural light. The tranquil surroundings highlight the peaceful waterfront setting.
Home in Lesbos
5.0 out of 5 average rating, 30 reviews

Ambelos, Lesvos Beach House

Welcome to Ampelos Cottage, an 85 sqm beachfront retreat where the sea is right at your doorstep. Blending modern comfort with authentic Greek charm, it’s the perfect escape for families and couples seeking relaxation and unforgettable moments. Wake up to the sound of the waves, enjoy coffee by the sea and watch the sunset with a glass of wine. Explore Molyvos, discover the tavernas of Anaxos, or simply unwind surrounded by breathtaking sea and mountain views.

Guest favorite
A spacious dining area features a long wooden table surrounded by modern black chairs. Large windows on either side allow natural light to fill the room, revealing views of the surrounding landscape. A stone fireplace adds a touch of warmth.
Home in Plomari
4.98 out of 5 average rating, 40 reviews

Iris Home

Η μεζονέτα μας Iris Home δυο επιπέδων πρόσφατα ανακαινισμένη βρίσκεται στο κέντρο της πόλης .Διαθέτει πλήρως εξοπλισμένη κουζίνα και τραπεζαρία για να απολαύσετε το φαγητό σας με την οικογένεια και τους φίλους σας με θέα τη θάλασσα .Οι δυο κρεβατοκάμαρες και το μπάνιο βρίσκονται στο κάτω επίπεδο συνεχίζουν την θέα στο απέραντο γαλάζιο του Αιγαίου .Στα 2 λεπτά με τα πόδια η μαρίνα της πόλης ,εστιατόρια ,καφετέριες και αλλά καταστήματα.

Guest favorite
The exterior showcases a two-story traditional building with maroon shutters framing the windows, which are adorned with white lace curtains. A small outdoor seating area features a patterned tablecloth, complemented by light-colored chairs, inviting relaxation in a serene setting.
Home in Taxiarches
4.82 out of 5 average rating, 116 reviews

PanDesSia

"PanDesSia" is a traditional house in Mytilene, with Lesbian architecture. It is located in "Kayani", close by the famous "Antonis" Ouzeri. Offers a veranda with a fantastic view of the Aegean Sea, the town and the harbor of Mytilene and the Turkish coasts. It is only 6km from the town of Mytilene and 4km from the airport. It has two bedrooms overlooking the sea and can accommodate at least 4 people.

Top guest favorite
A cozy seating area is positioned near large windows overlooking the sea. The stone wall adds a rustic touch, while two tall chairs with green cushions invite relaxation. Natural light floods the space, highlighting the nearby decorative items and the calm waters outside.
Home in Nyfida
4.94 out of 5 average rating, 35 reviews

Pelagia's House

Το Pelagia's house είναι ένα παραθαλάσσιο σπίτι που ανακαινίστηκε πρόσφατα κρατώντας όμως τον παραδοσιακό του χαρακτήρα μαζί με τις αναμνήσεις από πολλά ξενοιαστα καλοκαίρια. Το σπίτι διαθέτει 2 υπνοδωμάτια με ένα διπλό κ δύο μονα κρεβάτια, πλήρως εξοπλισμένη κουζίνα,πολύ άνετο μπάνιο, κλιματισμό κ wifi σε όλους τους χώρους Αυτό το παραθαλάσσιο σπίτι είναι ιδανικό για ήσυχες κ χαλαρωτικές διακοπές.

Top guest favorite
Home in Mytilini
5.0 out of 5 average rating, 22 reviews

Mytilene Luxury Villa | Garden level

Enjoy the private garden level apartment of our luxury villa with 3 bedrooms and panoramic views over Mytilene and the Aegean Sea. You’ll have a private entrance, exclusive use of the garden and outdoor areas, ensuring complete privacy. Just 5–7 minutes by car from Mytilene center, the port, and restaurants. Perfect for families and friends looking for comfort, style, and peace.

Top guest favorite
An open-plan living area features a light stone wall alongside a modern kitchen. A spacious beige sofa is complemented by two cozy poufs and a round area rug. Natural light filters through large windows, illuminating the space, while a dining table with wooden chairs is positioned nearby.
Home in Mytilini
4.91 out of 5 average rating, 22 reviews

Aeolian Apartment II

Discover the perfect blend of comfort, design, and convenience in our beautifully designed 2-bedroom home, just a 5-minute walk from the vibrant city center of Mytilene. Nestled in a peaceful neighborhood, our space is ideal for those who want to explore the city while enjoying a tranquil retreat.

Popular amenities for Mytilini house rentals

When is the best time to visit Mytilini?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceG$14,615 GYDG$14,197 GYDG$14,406 GYDG$17,120 GYDG$19,417 GYDG$20,043 GYDG$18,582 GYDG$21,713 GYDG$17,329 GYDG$15,659 GYDG$15,450 GYDG$15,032 GYD
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