
House vacation rentals in Mytilini
Find and book unique houses on Airbnb
Quick stats about house rentals in Mytilini

Total vacation rentals
Explore 100 vacation rentals in Mytilini

Nightly prices starting at
Mytilini vacation rentals start at G$4,176 GYD per night before taxes and fees

Verified guest reviews
Over 2,200 verified reviews to help you choose

Family-friendly vacation rentals
40 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 30 rentals that welcome pets

Rentals with dedicated workspaces
30 properties have a dedicated workspace

Wi-Fi availability
100 of Mytilini vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Mytilini rentals

4.8 Average rating
Mytilini stays are highly rated by guests—averaging 4.8 out of 5!
Top-rated house rentals in Mytilini
Guests agree: these houses are highly rated for location, cleanliness, and more.

Floras Charming Waterfront Villa
Flora's charming waterfront villa is located in the centre of the traditional picturesque village of Melinda, situated 6 km west of the village of Plomari. Our villa is situated literally on the beach, which is known for its crystal blue waters. The newly built modern house is fully equipped with all conveniences, such as a modern kitchen, air condition units in all rooms, tv, wi-fi etc. The famous traditional greek taverna of Maria is right next door, where you can enjoy local delicacies all day. In Our quiet villa you will experience greek at its summer, watching the sunset.
LocationFamilyWalkability

Beautiful Plomari Cottage
Newly renovated, spacious and stylish house in a quiet street at the heart of Plomari is a perfect place for couples, groups and families of up to 6 people. It boasts an ultra-high ceiling with a lovely gallery. Fully equipped kitchen, dining area, bedroom and full bathroom on ground floor; additional bedroom, full bathroom, open space with a sofa-bed in the gallery. Amoudeli beach is a 250m stroll. Important note: for safety reasons, children under 12 years old are not allowed up at the gallery
LocationFamilySleep quality

Perfect Beachfront Location
Set right on the beach in Skala Mistegnon, Kyparissis Beach House offers direct access to the sea and beautiful views across the Aegean. Guests can relax on the terrace or enjoy the outdoor seating area just steps from the shore. This spacious holiday home includes two bedrooms, two bathrooms, a comfortable living room, and a fully equipped kitchen. Additional features include air conditioning, a private balcony, and WiFi throughout the property. Take it easy at this unique and tranquil getaway.
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Aegean View Resort # The House
Tranquillity, relax and comfort best describe this house set in absolute nature in a peaceful suburb, only a few minutes away from the heart of the Mitilini. The property featuring stunning architectural details that provides guests with a high level of comfort and style but it can also be your base for exploring the rest of the beautiful and big island.It is perfect for families, couples or a group of friends looking for spacious areas, large terraces, comfort and privacy.
ValueFamilyBeach

Ambelos, Lesvos Beach House
Welcome to Ampelos Cottage, an 85 sqm beachfront retreat where the sea is right at your doorstep. Blending modern comfort with authentic Greek charm, it’s the perfect escape for families and couples seeking relaxation and unforgettable moments. Wake up to the sound of the waves, enjoy coffee by the sea and watch the sunset with a glass of wine. Explore Molyvos, discover the tavernas of Anaxos, or simply unwind surrounded by breathtaking sea and mountain views.
LocationFamilyCleanliness

Pierres Blanches Residences 2
Discover the ultimate accommodation experience 1.5 km from the city center of Mytilene. With elegant design and modern amenities, our three autonomous detached houses, 120 sq.m. each, invite you to enjoy the tranquility and beauty of the island. Each villa has three comfortable bedrooms, two bathrooms, a spacious living room, an attic, a fully equipped kitchen and a private pool to cool off and enjoy the sun in the comfort of your own pool.
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Ioanna's traditional house in the center of 140m2
Traditional building, built in 1880, in the historic city center. Renovated in 2008. It is aimed at lovers of authenticity, antiques and art! Ideal for a romantic vacation (the choice of honeymooners). It offers a comfortable stay for families with young children and babies! A 5-minute walk from the port and the beach, cafes, restaurants, bars, as well as most of the attractions of Mytilene! Children under 12 stay free of charge!
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Iris Home
Our two-level recently renovated maisonette Iris Home is located in the city center. It has a fully equipped kitchen and dining area to enjoy your food with your family and friends overlooking the sea. The two bedrooms and the bathroom are on the lower level and continue the view of the endless blue of the Aegean Sea. Within a 2-minute walk, you can find the city's marina, restaurants, cafes and other shops.
LocationFamilyBeach

PanDesSia
"PanDesSia" is a traditional house in Mytilene, with Lesbian architecture. It is located in "Kayani", close by the famous "Antonis" Ouzeri. Offers a veranda with a fantastic view of the Aegean Sea, the town and the harbor of Mytilene and the Turkish coasts. It is only 6km from the town of Mytilene and 4km from the airport. It has two bedrooms overlooking the sea and can accommodate at least 4 people.
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Mytilene Luxury Villa | Garden level
Enjoy the private garden level apartment of our luxury villa with 3 bedrooms and panoramic views over Mytilene and the Aegean Sea. You’ll have a private entrance, exclusive use of the garden and outdoor areas, ensuring complete privacy. Just 5–7 minutes by car from Mytilene center, the port, and restaurants. Perfect for families and friends looking for comfort, style, and peace.
FamilyValueHospitality

Pelagia's House
Pelagia's house is a seaside house that has been recently renovated while keeping its traditional character along with the memories of many carefree summers. The house has 2 bedrooms with one double and two single beds, a fully equipped kitchen, a very comfortable bathroom, air conditioning and wifi in all areas This seaside house is ideal for a quiet and relaxing vacation.
FamilyLocationQuiet

Villa olya plomari
A unique private villa in Plomari, with a breathtaking sea view, a quiet place, next to a pine forest with a luxurious private infinity pool and in the courtyard two sun beds and a dining area under an olive tree in front of the beautiful view of the sea and the village of Plomari. A perfect vacation.
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Popular amenities for Mytilini house rentals
House rentals with a pool

Ouzo Traditional House with privatepool & parking
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Eros' sea view Mytilini (A)
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Tranquil Haven with private pool by Sea Sun
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Galini Ducks
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Twostorey house with amazing view (Aqua)
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Ouzo Panoramic House 2A (3BR with private pool)
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Spacious Villa with Pool & Sea View in Cunda
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Eleia Villa with Private Pool and Sea View
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Weekly house rentals

Kiki's house in the castle
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Detached house in the city center
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Villa Caroline
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Beachfront retreat on an island
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Traditional Stone House in Seafront Olive Grove
LocationBeachGrill

the Workshop
LocationFamilyAccuracy

Modern house by the sea
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Modern House in Mytilene Center
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Private house rentals

MOLAV Apartment
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Green House
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Casa De Pera Ermou
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4 εποχές
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Eliana's downtown studio
LocationFamilySleep quality

Agiasos Classic Stone House
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D. Bernardaki Garden House
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Gina 's Cozy nest in Mytilene
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When is the best time to visit Mytilini?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$14,615 GYD | G$14,197 GYD | G$14,406 GYD | G$17,120 GYD | G$19,417 GYD | G$20,043 GYD | G$18,582 GYD | G$21,713 GYD | G$17,329 GYD | G$15,659 GYD | G$15,450 GYD | G$15,032 GYD |
| Avg. temp | 8°C | 9°C | 11°C | 15°C | 20°C | 25°C | 28°C | 28°C | 23°C | 19°C | 14°C | 10°C |





