Guesthouse vacation rentals in Mississippi

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Top-rated guesthouse rentals in Mississippi

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Guest favorite

Guesthouse in Ecru

4.96 out of 5 average rating, 255 reviews

The Doughboys Cottage

Private full bath Queen Bed Cottage near Natchez Trace Park & Mississippi's premier biking destination, Tanglefoot Trail. Perfect for single or double occupancy. 25 miles from Elvis Presley Birthplace 35 miles from The University of Mississippi and Rowan Oak, the home of William Faulkner. Enjoy a fresh pan of The Doughboys Fresh Baked Cinnamon Sticky Buns $12.00. Delivered to your door in a.m. Local venues: Great Mexican Restaurant 2 miles Walmart 3 Miles Convenient Store 1/4 mile

Dec 29 – Jan 5

G$19,106 GYD per night

Guest favorite

Guesthouse in Bay Saint Louis

4.96 out of 5 average rating, 378 reviews

Cozy efficiency cottage near beach & entertainment

Cozy efficiency cottage 1 block from beach & close to old town Bay St Louis shopping & dining. Fenced private yard. Dogs welcome for $20 fee each but please notify host of # & type of dogs. Owner lives in house next to cottage but offers privacy & freedom to come and go as you please. Sleeps 2 comfortably in double bed. Twin day bed offers another sleeping space. Refrigerator, portable induction cooktop, microwave, coffee maker & toaster/convection oven. Charcoal grill & fire pit available

Nov 5 – 12

G$19,505 GYD per night

Guest favorite

Guesthouse in Hernando

4.98 out of 5 average rating, 119 reviews

Guesthouse 1 bed, beautiful views NO cleaning fees

Relax at our adorable 1 bedroom quite hide-a-way, but still have the convenience of being located close to everything. There are beautiful views from the front covered porch. Also located about 20 minutes from Memphis and Tunica Casino Strip. Enjoy local attractions: Hernando Town Square, Snowden Grove, Shopping, Graceland, Memphis Botanic Gardens, Museums and Beale Street. This area and home is made for family life, not for the party style, come and enjoy your tranquil stay with us.

Jan 16 – 23

G$23,035 GYD per night

Guest favorite

Guesthouse in Como

4.97 out of 5 average rating, 114 reviews

Heavens Trees: Small town Guest House

Cute comfortable guest house in small Mississippi town. Como is 40 miles south of Memphis and 40 miles from Oxford , MS. Take in a Ole Miss game or check out Beale St. We are within walking distance of Main Street in Como where you can find great restaurants and antiques. Coffee, tea and continental breakfast with snacks and bottled water provided. Swim in our lovely pool, sip your morning coffee sitting on the screened in porch overlooking the pool and pasture with 4 mini horses.

Jan 4 – 11

G$30,083 GYD per night

Guest favorite

Guesthouse in Laurel

5.0 out of 5 average rating, 223 reviews

Woodland Cottages- Sycamore

Enjoy easy access to popular shops and restaurants inLaurel from this cozy cottage. Our home was featured on HGTV’s HomeTown. While we live in the main house, we had Katie (contractor on show) remodel the two rooms behind us as guest rooms. We have added carvings to the landscape, a whole house generator, and a few places to sit and enjoy the outside. Our episode was called Woodland Wonderland, but better known as the Hobbit House. Isao and I would love to welcome you to Laurel, MS.

Nov 13 – 20

G$26,378 GYD per night

Guest favorite

Guesthouse in Laurel

4.99 out of 5 average rating, 766 reviews

The Laurel Cottage - stay with Mallorie!

Our cozy cottage is nestled in the heart of the historic district, on the grounds of a Laurel landmark home, built in 1907. The Cottage is the entire first floor of the Carriage House that is original to the property with all the lovely historic charm. Recently renovated, you’ll rest easy with all the modern day conveniences . Thoroughly cleaned and sanitized after each checkout. The perfect getaway for anyone wanting to experience downtown and HGTV’s Home Town!

Dec 9 – 16

G$40,439 GYD per night

Guest favorite

Guesthouse in Hattiesburg

5.0 out of 5 average rating, 115 reviews

Historic Downtown Carriage House & Oasis

Conveniently located within walking distance to downtown, restaurants, and shopping. This private carriage house sits in the Historic District behind a 1910 Grand Victorian which is listed on the National Historic Registry. The carriage house has been newly renovated and is situated atop the garage. Features a modern full kitchen, king bed, living area with pull out sofa for extra sleeping if needed, and full bathroom.

Mar 9 – 16

G$21,442 GYD per night

Guest favorite

Guesthouse in Hattiesburg

4.96 out of 5 average rating, 164 reviews

The Cottage @ West Pine - Downtown Hattiesburg

Welcome home to the coziest Cottage there is, near Downtown Hattiesburg! This 1 bed, 1 bath has recently been remodeled from top to bottom, so all you have to do is come in, relax, and enjoy all the perks of a fresh new home. The Cottage is conveniently located within minutes to USM, Midtown, Forrest General Hospital, Hattiesburg Amtrak, Kamper Park, Camp Shelby, restaurants, shopping, and so much more!

Jun 19 – 26

G$19,721 GYD per night

Guest favorite

Guesthouse in Laurel

4.98 out of 5 average rating, 245 reviews

Cozy Apartment Located in Downtown Laurel

We are located in the heart of Downtown Laurel, on the picturesque tree lined Euclid Ave. You’ll enjoy our newly renovated 800 square foot upstairs apartment located behind the main house. The perfect getaway for anyone wanting to be in the middle of the action of Downtown Laurel and HGTV's Home Town. Come stay with us and experience some true southern hospitality.

Dec 3 – 10

G$25,742 GYD per night

Guest favorite

Guesthouse in Tishomingo

4.91 out of 5 average rating, 232 reviews

Bear Creek Saloon Guesthouse

The Bear Creek Saloon Guesthouse is situated on 3 peaceful acres conveniently located 1 mile off of the Natchez Trace Parkway in Tishomingo, MS. Guest suite includes queen/twin beds, kitchen, full bath, and laundry area. Each guest is given access to the 1st floor guest suite only, but complete privacy during their stay. I am not on site, but have staff close by.

Jul 4 – 11

G$22,780 GYD per night

Guest favorite

Guesthouse in Raymond

4.95 out of 5 average rating, 186 reviews

Hope's Treasure

Hope's Treasure is just that--a sweet retreat less than 15 minutes from Mississippi College and Hinds Community College. With 2 bedrooms, a private bathroom, a comfortable living room, and a kitchenette, you can relax and enjoy some beautiful sunsets in a peaceful wooded setting. A picturesque half-mile drive leads from the gated entrance to your getaway.

Feb 27 – Mar 6

G$18,166 GYD per night

Guest favorite

Guesthouse in Kiln

4.86 out of 5 average rating, 155 reviews

T-Bohn Bayou Bungalow

Cute studio cabin guesthouse with all the conveniences of home. Nothing fancy, but simple country living located in Kiln, Mississippi - a small rural town 15-30 minutes from Bay St. Louis, Waveland, Gulfport, Long Beach, and Biloxi. Easy access to great local restaurants, breweries, parks, museums, and other attractions.

Jul 30 – Aug 6

G$15,918 GYD per night