Hotel vacation rentals in Mississippi

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Top-rated hotel rentals in Mississippi

Guests agree: these hotel rentals are highly rated for location, cleanliness, and more.

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Guest favorite

A comfortable seating area is showcased with a green couch adorned with pillows and a soft blanket. A wooden coffee table sits on an area rug, while a lamp illuminates the side table. Exposed brick walls add character, and natural light enters through a window.

Hotel room in Picayune

4.92 out of 5 average rating, 50 reviews

The Depot Suites Suite 201

Downtown Picayune. Come and enjoy a charming stay at one of our three newly renovated suites. The festive atmosphere of our downtown life and modern boutiques will please any desire to sit back and relax. Enjoy one of our downtown restaurants and full bars with great music and often live bands. Minutes away from New Orleans or the Mississippi Gulf Coast. Sit outside on the balcony and take in a beautiful sunset. Each suite allows guest to have their own space creating an at home Southern

Top guest favorite

A cozy seating area is highlighted by a decorative chair upholstered in deep blue fabric. A patterned cushion enhances the comfort. A small table holds a lamp and a floral arrangement, while a round mirror reflects light, adding depth to the space.

Hotel room in Ocean Springs

4.95 out of 5 average rating, 187 reviews

Mockingbird Inn- Fern Suite

*TRUE SOUTHERN CHARM* Built in 1899 and newly renovated, The Mocking Bird Inn- Fern Suite is nestled on a LIVE OAK lined historic street. The home will surround you with a modern coastal warmth. FORT BAYOU is located next to the property so, take a stroll next door to MARBLE SPRINGS PARK for a view of the bayou and learn the history of the NATURAL SPRINGS that gave Ocean Springs its name. Just 1 block to DOWNTOWN OS GALLERIES, SHOPPING & RESTAURANTS , 1 mile to the BEACH, 2 miles to CASINO's

Superhost

A cozy sitting area is presented with comfortable seating and a television. Light-colored walls are complemented by wood accents. A small table is situated near the doorway, while a refrigerator is visible in the background. A colorful rug enriches the space.

Casa particular in Lyon

4.96 out of 5 average rating, 47 reviews

Safest Place in Clarksdale Come Visit With Us

The barn house apartment is cozy and comfortable with 2 spacious bedrooms, 1 and a half baths, laundry room., full kitchen and sitting area. Close and easy access to downtown Clarksdale and Helena, AR for blues fans. 5 miles from Ground Zero Blues Club and downtown Clarksdale 5 miles from historic Hwy 49 & Hwy 61 Crossroads 20 miles from Moon Lake 26 miles from Isle of Capri Casino 4.4 miles from Northwest Regional Medical Center 20 miles from O'keef WMA 75 miles from Memphis Intl Airport

Guest favorite

A bright bedroom features a spacious bed dressed in white linens with light pink accents. Two bedside lamps provide soft lighting, while colorful artwork hangs above the headboard. Tall curtains frame a window, allowing natural light to fill the room, enhancing its comforting atmosphere.

Hotel room in Natchez

5 out of 5 average rating, 6 reviews

The Big Muddy Inn-Robert Johnson Suite

Just a stone's throw from the Mississippi River, the Big Muddy Inn is a place to lie down in one of our suites or get down in the Blues Room. The Big Muddy features six art-filled and elegantly designed rooms, a welcoming staff that embodies the definition of Southern hospitality, and a lively Blues Room that plays host to talented musicians and seats up to fifty people. With 6,000 square feet of beautifully renovated elegance, the Big Muddy Inn awaits you in downtown Natchez, Mississippi.

The porch features a welcoming entrance with a white door and a large oval window. A small round table accompanied by two chairs sits on a decorative rug, surrounded by wooden railings and views of greenery beyond.

Casa particular in Waveland

4.6 out of 5 average rating, 63 reviews

Homey Hideaway

Welcome to the Homey Hideaway! 🏡 Escape to a charming, homey retreat neslted in a peaceful blue collar TRAILER PARK. With a comfy living area, fully equipped, kitchen, and snug bedrooms, this place is perfect for a relaxing getaway. Your morning ☀️ , coffee ☕️ on the porch or unwind under the stars ✨ . Only minutes away from the beaches, casinos, Buccaneer State park, NASA Infinity Science Center, and good ol’ down town Bay St. Louis. Bonus: NOLA is located only about 60 miles away! 🤩

Guest favorite

A well-appointed room is featured with two spacious beds, complemented by colorful decorative pillows. A kitchenette, equipped with modern appliances, is located along one wall. Soft lighting from a bedside lamp adds warmth to the serene atmosphere. Light wooden flooring enhances the overall design.

Hotel room in Starkville

4.93 out of 5 average rating, 15 reviews

MSU Boutique Hotel w Kitchenette

Welcome to the Far Out Motel, just a stone's throw from MSU! Step into a blast from the past with our retro-inspired rooms, revamped with a modern twist for your ultimate comfort. Enjoy our stylish outdoor patio and lounge area, perfect for unwinding or socializing after a day of exploring. Located conveniently downtown, you'll have the best of Starkville’s dining and nightlife right at your doorstep. Experience the perfect blend of nostalgic charm and contemporary convenience.

Top guest favorite

A charming outdoor area is depicted with vibrant orange and white striped umbrellas providing shade over a patio. Colorful adirondack chairs are arranged on the lush green lawn, surrounded by various flowering plants and well-maintained landscaping, creating an inviting atmosphere.

Hotel room in Ocean Springs

5 out of 5 average rating, 14 reviews

Best location,pet friendly,huge yard at the Porch

Newly renovated, this warm & inviting 1 bedroom cottage allows a perfect retreat romantic enough for a couple ready to enjoy the night life or walks by the beach & comfortable enough to house three guests looking to experience the parades & other family-friendly entertainment. Located within walking distance to the beach, shopping, dining, festivals & galleries, the suite consists of 1 bedroom, 1 bath, separate living room w/ a futon sofa sleeper, wet bar, and walk-in shower.

Guest favorite

A spacious sleeping area features a contemporary black headboard and crisp white bedding accented by a rich red throw blanket. The room is illuminated by subtle recessed lighting along the ceiling, creating a modern atmosphere. A stylish feature wall adds texture to the design.

Hotel room in New Albany

5 out of 5 average rating, 5 reviews

Honeymoon Suite By BW

Welcome to a space where creativity meets comfort. Every corner is designed to inspire and relax, from vibrant artwork to sleek furniture. Thoughtful details, like custom décor and Lovely Hot tub, make this place uniquely yours. Whether you're unwinding, or socializing, this space adapts to your needs. It's not just a room; it's an experience—a perfect blend of style, functionality, and tranquility. Here, every moment feels special and every detail counts.

Top guest favorite

A hallway features vibrant artwork depicting musicians on the walls, complemented by a cozy seating arrangement. A medium-sized area rug adds warmth to the wooden flooring, while natural light filters in from the windows at either end, creating an open and welcoming ambiance.

Shared room in Clarksdale

5 out of 5 average rating, 55 reviews

Hostel Downtown Prime Location - Bed in 8 Bed Dorm

Best Location, Free Parking, Free Wifi, Large Kitchen, Large Common Areas. Auberge Clarksdale is a new boutique co-living environment located in downtown Clarksdale. Locally inspired decor. Very comfortable beds. WiFi throughout. Private Rooms and Dorm Rooms. Within 2 blocks of Delta Blues Museum, Ground Zero BC, Red's Juke Joint, Cat Head Records, Hooker Grocery, Hambone Gallery, and many other hot-spots and restaurants.

Guest favorite

A spacious bedroom features exposed brick walls and wooden beams, creating a rustic atmosphere. A grand wooden bed is complemented by two bedside lamps. A seating bench is positioned at the foot of the bed. Natural light enters through a large window, enhancing the room's open feel.

Hotel room in Natchez

4.94 out of 5 average rating, 244 reviews

The River Walk Inn - Room 801

Spacious upstairs room in a charming 1840's building located on top of the bluff with exquisite views of the MS river. This room has beautiful period furniture, a Keurig, mini fridge, access to a shared balcony, ice machine, washer/dryer, and is within walking distance to all events downtown. Please note that the rooms are above a popular restaurant/bar that frequently offers live entertainment on the weekends.

Guest favorite

A cozy sitting area features a white daybed adorned with soft cushions against a backdrop of exposed brick walls. Natural light filters through sheer curtains, illuminating a circular table with a decorative lamp and a charming floral arrangement. Rustic wood beams enhance the room's character.

Hotel room in Carthage

4.88 out of 5 average rating, 33 reviews

Room 1 (sleep1) Chipley's Squareview Inn & Venue

This newly renovated Boutique Inn combines old-world grandeur from the original 1929 design of the Chipley office building with modern appointments and contemporary amenities. No detail is overlooked in the rustic elegance of this charming space, featuring seven uniquely styled rooms with ensuite marble baths, and all new kitchenettes. Beautiful antiques, cozy comforts and sunlit views grace every private space.

Guest favorite

A modern suite is equipped with a practical coffee station and a decorative mirror. Two green sofas are positioned next to a bedside table and lamp, providing a cozy lounging area. The spacious bed is visible in the background, contributing to a comfortable atmosphere.

Hotel room in Laurel

4.88 out of 5 average rating, 137 reviews

Hotel Pinehurst- Jean Theatre, Suite 103

Located in the heart of beautiful downtown Laurel, this property was once home to the famous Jean Theatre and The Old Roses Slipper Shop. The property has nine spacious, luxurious hotel style rooms with access to a balcony overlooking Central Avenue. The famous Pearl's Diner, Lauren Rogers Museum, multiple restaurants and iconic buildings are within close walking distance to this property.