
Vacation rentals in Midlands of South Carolina
Find and book unique accommodations on Airbnb
Top-rated vacation rentals in Midlands of South Carolina
Guests agree: these stays are highly rated for location, cleanliness, and more.

Congaree Vines - Woodland Cottage by a Vineyard!
-Enjoy a Quiet Country Stay! This charming European style cottage is set by a Hobby Vineyard! Enjoy complimentary port wine from our vineyard, a fire pit and hammock under the stars! -Congaree Vines also has the Log Cabin Library for guest use & the Barn Bungalow to rent. Pets are welcome for a fee; service dog: bring paperwork. -We are near Congaree National Park (33 min), Columbia, USC, Ft. Jackson, Airport, I-26 & Hwy 77. -15% off Guided Kayak in CNP w/Carolina Outdoor Adventures.
ValueLocationOutdoor spaces
4.96 out of 5 average rating, 760 reviews
Lake House with amazing view
Lake front property located on Lake Murray across from Dreyer Island State Park-Create memories with families & friends-/spacious/4 large bedrooms, 3 full baths/Accommodates up to 8 guests with a large master suite and master shower/infant’s crib is available/Large flat screen TV/ Wi-Fi/Washer and dryer/Great space for any group size/Wrap-around balcony/Gazebo/Great outdoor space with amazing views/ enjoy morning ☕️ & evening 🍷 /private boat dock. Space for yoga and all. Let’s relax a little!
FamilyLocationIndoor spaces
4.96 out of 5 average rating, 109 reviews
Restful Lakeside Cottage -Dogs allowed
This pond-side cottage is a peaceful place to relax & unwind. Sit in the sunroom and enjoy watching the birds & the water or enjoy the front porch rockers where you can listen to the birds & frogs. We are 12 min. from downtown Sumter & 20 min from Shaw AFB. Local points of interest are Swan Lake Iris Gardens, Poinsett State Park & Congaree Nat. Park. It's only 2 hrs to Myrtle Beach or Charleston & 3 hrs to the mtns. While it's conveniently located, this cottage offers a quiet place to relax.
FamilyLocationCheckout
4.97 out of 5 average rating, 539 reviews
The Historic Selwood Cottage @theselwoodcottage
Private, historic cottage with screened in porch. Sleeps 5 in 2 bedrooms with full, furnished kitchen. PET FRIENDLY. Property owners on shared property available to help with any needs. Enjoy over an acre of private land in the heart of the city. Lake Murray within walking distance as well as Harbison shopping area 5 miles away and downtown Columbia 15 miles away. *NO PARTIES TOLERATED NO SMOKING INSIDE OR OUTSIDE* If your dates are unavailable ask about our other Airbnb “Otto the Airstream.”
FamilyValueLong stay
4.97 out of 5 average rating, 660 reviews
A relaxing cabin on private pond. Old Bells Secret
Escape to our secluded cabin on 90 acres in St. Matthews, SC! This early 2000s style cabin features 2 cozy bedrooms, 1 bathroom, and a lovely porch. The large pond is perfect for swimming, fishing, or playing. It’s an endless adventure. The house can sleep up to 6 with the pull out couch. Accessible via a private road, it's perfect for weekend getaways with the family or housing for workers. Experience relaxation and adventure in nature at this wonderful cabin. Book now for a memorable stay!
FamilyLocationCondition
4.76 out of 5 average rating, 206 reviews
Pear Tree Farm-pets welcome! Stables/paddocks too!
Relax with the family at this peaceful place with GORGEOUS sunsets. When we say family, we mean pets & horses as well! We have 12 stables, 7 paddocks. Fenced yard & in ground pool. 5 fireplaces & heart pine floors. 3 living/family rooms. Once owned by the DuPont family (yes that DuPont family), the main part of the home is 96 yrs old and has many charming details. The 4 car garage was also the site of building race cars for the DuPonts. Pear Tree Farm offers the best in country quaintness.
ValueFamilyAccuracy
4.85 out of 5 average rating, 123 reviews
Sunset Cove-Beautiful Lake views
Your home away from home on Lake Murray! Spacious, modern clean, home with 3 levels of living -3 spacious decks, screen porch, and sunroom all with massive lake views! Plenty to do at Sunset Cove relaxing with family and friends and toys galore! "Wow just wow, best Airbnb ever..Sarah, June 2026. "..clean, beautiful view and so many fun games..Lisa, Oct 2025."Perfect setting for a quiet getaway. The house was amazing, clean, and had all the amenities we were looking for.."Jay, Sept 2025
ValueLocationAccess
4.91 out of 5 average rating, 107 reviews
3 bd, 2ba, near ShawAFB, Game Rm
Welcome to our newly renovated 3 Bed, 2 Bath, home in Sumter. Our modern decor home has the following: - Master bdrm with King bed/ ensuite bath - Queen beds other rooms - Full equipped kitchen, coffee station - 65", 55", 43" TVs in rooms - Game Room, w/ pool table, table tennis, arcade games - Work area, wifi, 32" monitor, printer, adj height desk - Private backyard, BBQ grill ,gazebo, fire table, games. - Centrally located near Shaw AFB, Tuomey Hospital, food, parks and more
LocationValueKitchen
4.99 out of 5 average rating, 136 reviews
Golden Reflections Getaway
Welcome to the Golden Reflection Getaway—a spacious, stylish retreat perfect for families and groups. Enjoy this 2,600+ sq. ft. spacious family area with three luxury themed bedrooms upstairs and extra sleeping options with a full bathroom on the main level. Tucked away in a peaceful neighborhood, just 7 minutes from the vibrant heart of Downtown Columbia and 18 minutes from Fort Jackson. Relax, recharge, and make lasting memories in this thoughtfully designed and comfortable home.
LocationFamilyOutdoor spaces
4.99 out of 5 average rating, 163 reviews
Big Water Sunset at Lake it Easy
Escape to Beautiful Lake Wateree for a relaxing weekend away with friends or family. This updated house features 2 bedrooms & 2 bathrooms. Enjoy the cozy vibes of a tastefully decorated space, perfect for unwinding after a day on the lake. Step outside to a serene screened in porch, a fire pit, and stunning big water sunsets that will take your breath away. Whether you're into fishing, kayaking, or simply relaxing by the water, this lakefront house has something for everyone!
FamilyLocationAccuracy
4.95 out of 5 average rating, 123 reviews
Modern Retreat - King Bed - Downtown - Ft. Jackson
Come relax in this newly remodeled open-concept 2 bedroom 1 bathroom duplex. Located on a quiet street that is 5 minutes to Downtown, Devine St., Trenholm Plaza and Ft Jackson. Home includes keyless front door entry and a private driveway. The master bedroom has a King bed and 43" TV. The second bedroom has a queen bed, a 43" TV and a desk with a quiet work space. Fast Internet with Download speeds over 400 Mbps. Live tv provided through YouTubeTV. STRN-003126-06-2023
LocationValueComfort
4.98 out of 5 average rating, 164 reviews
Private 75 acre farm with lake
Quiet getaway at Lake Tom-A-Shawna Farm. Fully furnished 2 queen bed, 1 full bath, mini cabin that offers accommodations for traveling professionals, equestrians, and vacationers. This gated private property spans 75 acres, including a 20-acre lake, and features a 4-person cabin with full appliances, granite countertops, high-speed internet, 2 TVs, an electric fireplace, heat/AC, deck. Fishing, shooting, hiking or just relaxing. We offer fresh eggs and meat for purchase.
ValueLocationLayout
4.98 out of 5 average rating, 129 reviewsPopular amenities for Midlands of South Carolina vacation rentals
Other great vacation rentals in Midlands of South Carolina

Lizzi & Scott’sTiny Guest House secluded USC-Vista
LocationFamilyWalkability
4.9 out of 5 average rating, 1067 reviews
Historic Log cabin on private fishing lake
FamilyLocationKitchen
4.91 out of 5 average rating, 198 reviews
Panoramic Lakefront with Hot Tub
LocationValueIndoor spaces
4.95 out of 5 average rating, 126 reviews
Elmwood Retreat for Remote Work & Family Fun
ValueLocationLayout
4.99 out of 5 average rating, 481 reviews
The Carolina Cottage: Near Ft Jackson, Zoo & 5pts!
ValueFamilyLayout
4.87 out of 5 average rating, 314 reviews
Lake front Lake Murray in the Heart of Lexington
ValueFamilyParking
4.97 out of 5 average rating, 176 reviews
Freshly New House
ValueLocationGrill
4.96 out of 5 average rating, 157 reviews
Anchors Aweigh
FamilyValueDecor
5.0 out of 5 average rating, 205 reviewsDestinations to explore
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- University of South Carolina
- Congaree National Park
- Riverbanks Zoo and Garden
- Williams Brice Stadium
- South Carolina State House
- South Carolina State Museum
- West Columbia Riverwalk Park and Amphitheater
- Columbia Museum of Art
- Colonial Life Arena
- Saluda Shoals Park
- Sesquicentennial State Park
- Columbia Metropolitan Convention Center
- Dreher Island State Park
- Edventure
- Riverfront Park
- Soda City Market
- Koger Center for the Arts
- Lake Murray Dam North Recreational Area
- Segra Park
- Frankie's Fun Park





