Vacation rentals in Midlands of South Carolina

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Top-rated vacation rentals in Midlands of South Carolina

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite

Guest suite in Columbia

4.91 out of 5 average rating, 242 reviews

Comfy & Private Left Half of a Duplex

Listing is a private and cozy half of a duplex. Guests will have access to a private entrance and parking in a quiet neighborhood. The bathroom has a shower/tub provided with towels, shampoo/conditioner, lotion, soap. One bedroom has queen bed, walk-in closet, and TV. Kitchenette has a sofa lounger, microwave, mini fridge, TV, coffee maker (single cup/round pad inserts), dishes. *1 mile from Saluda Shoals park and Lake Murray. *4 miles from Columbian Mall - tons of shopping and restaurants .

Sep 9 – 16

G$17,849 GYD per night

Guest favorite

Cottage in Sumter

4.96 out of 5 average rating, 369 reviews

Restful Lakeside Getaway Cottage -Dogs allowed.

This pond-side cottage is a peaceful place to relax and unwind. Sit on the enclosed porch and watch the water or enjoy the front porch swing where you can listen to the birds and frogs. We are 12 min. from downtown Sumter and 20 min from Shaw AFB. Local points of interest are Swan Lake Iris Gardens and Poinsett State Park. It is only 2 hours to Myrtle Beach and Charleston, SC & 3 hrs to the mtns. While it is conveniently located, this cottage offers a quiet place to put your feet up and rest.

Nov 21 – 28

G$23,853 GYD per night

Guest favorite

Guesthouse in Columbia

4.98 out of 5 average rating, 126 reviews

❃ The Rosewood Loft ❃ Desk, Kitchen & Laundry

STRO-004413-11-2023 Wonderfully comfortable, quiet, clean, and spacious loft in the heart of Rosewood, one of Columbia's most convenient, safe, and popular neighborhoods! ★ 8-minute drive to Founders Park, home of USC Baseball. ★ Minutes from USC campus, Fort Jackson and downtown Columbia. ★ 6 min walk to groceries (Publix), several restaurants and a brewery. ★ Quiet and walkable neighborhood. ★ Secure, off-street, 1-car parking behind a 6' fence. ★ Seamless check-in with keypad lock.

Sep 2 – 9

G$24,289 GYD per night

Guest favorite

Home in Sumter

4.96 out of 5 average rating, 110 reviews

The Corner Cottage

Location location! The "Corner Cottage" is a cozy home in the center of Sumter, right along a main street. Full of charm, this wee old house provides two stylish bedrooms, an office space, a like-new bathroom, and an updated kitchen. We are less than a mile from the beautiful Swan Lake Gardens, and shopping and dining are just around the corner. We're also not far from Shaw Airforce Base and the 95. Weary travellers welcomed! You won't find a more convenient home-base for your Sumter stay.

Sep 10 – 17

G$20,471 GYD per night

Guest favorite

Cabin in Batesburg-Leesville

4.93 out of 5 average rating, 126 reviews

Charming Cabin on Lake Murray

Kick back and relax in this calm, stylish space. Enjoy reading, boating, swimming and beautiful views of Lake Murray. If you have a pet there is tons of space for them to run around and even go swimming in the lake. The location is a bit remote, so it is super quiet and serene. There is a gas station, Dollar General, and restaurants 5 minutes away. It is a central location: 10 minutes from the town of Saluda, 10 minutes from Batesburg, 20 minutes from Newberry, and 20 minutes from Lexington.

Mar 24 – 31

G$25,130 GYD per night

Guest favorite

Cottage in Gilbert

4.97 out of 5 average rating, 106 reviews

Peaceful, Lakefront Cottage

Our simple, unique (octagonal) cottage is ready for you to enjoy as you take in the serenity of Lake Murray! Have a meal on the spacious deck, go swimming/fishing from the dock, or just relax and observe the many fish, turtles and birds that live in this quiet cove. Our boat is on one side of the dock, and you’re welcome to use the other side for yours. There is a public boat ramp less than a mile away. Siesta Cove is the next cove over and has a general store and gas pumps for your boat.

Sep 20 – 27

G$29,109 GYD per night

Guest favorite

Cottage in Aiken

4.97 out of 5 average rating, 164 reviews

Sweetgrass Cottage

Sweetgrass cottage is light and bright and new, with windows everywhere to let guests enjoy the view. It is a perfect getaway for singles or couples looking to explore Aiken SC and surrounding areas. Located in Three Runs Plantation, Aikens Premier Equestrian Community, Sweetgrass cottage is within minutes of many equestrian venues as well as being close to Augusta GA, home of the Masters golf tournament. Relax on the front porch or spend your days exploring the historic district in Aiken.

Jun 17 – 24

G$20,592 GYD per night

Guest favorite

Farm stay in Aiken

5.0 out of 5 average rating, 107 reviews

The Guest House & Stables at Quiet Oak Farm

2.5 miles to downtown Aiken and all horse show spots! The ultimate Location offers complete privacy with all the Aiken charm and a luxury equestrian experience! 5.5 acre Quiet Oak Farm was professionally designed & decorated using every inch of space. The guest house has been thoughtful built into our state of the art 2500 sq ft barn. Using luxury finishes and personal touches for a memorable stay. We invite you to enjoy our little space with big style in the “Best Small Town in America”!

Aug 2 – 9

G$23,810 GYD per night

Guest favorite

Tiny home in Sumter County

4.96 out of 5 average rating, 129 reviews

The Cabin at Minehill

Our cabin is located in Stateburg, SC between Columbia and Sumter and within a 5-15 minute commute to Shaw AFB and Sumter. It is a convenient stop between I-77 and I-95 and has close proximity to Poinsett and Congaree Parks and The Palmetto Trail. It sits on top of a hill offering panoramic views, quiet, and privacy. Mine Hill sunrises and sunsets are stunning. Reserve as a stopover, a retreat from the workday, or a romantic getaway and enjoy our cabin as a home away from home.

Jun 24 – Jul 1

G$19,215 GYD per night

Guest favorite

Treehouse in West Columbia

4.99 out of 5 average rating, 522 reviews

Luxury Treehouse in the heart of Columbia

Mid-Century Modern Treehouse with no stairs to climb but walk across a bridge thru beautiful professionally landscaped gardens onto a spacious deck with a hot tub. The view is over a bubbling creek set back into the woods. The barbecue grill and fire pit area complete with a twinkling chandelier and string lights. Relax inside and curl up and watch a movie in front of the fireplace! You have parking next to a walkway located between the treehouse and gardens next to our home.

Dec 17 – 24

G$41,885 GYD per night

Guest favorite

Guesthouse in Camden

4.91 out of 5 average rating, 265 reviews

Camden Coach House Long term stay southern balance

Renovated 10/2023 Experience Camden like ancestors in last large tract of land bordering business district and horse community. Hike 4mi private trails connect Springdale stable, Camden country club between work on 500mb inet. No lost power generator keeps you connected. Southern custom Tulip maple sink, Spa Shower, 200 year old barn door, board n batten exterior surrounds you in history. ・24/7 pro staff ・Security gate, cams ・Full kitchen ・Laundry ・Fountains ・gardens ・pond

Sep 22 – 29

G$22,849 GYD per night

Guest favorite

Guest suite in Chapin

4.98 out of 5 average rating, 454 reviews

LAKE FRONT SWEET - Dog Friendly

In Chapin on beautiful Lake Murray near Dreher Island State Park. Enjoy the view from the patio, relax on our dock, or float in the lake! There's room for your boat and trailer. Lower level of the house is all yours- incl. bedrm, bathrm, living rm & patio. Kitchenette-No stove, but there's a small kitchen sink, gas grill, full size fridge, microwave, toaster, coffee maker & dishes. We provide linens, coffee, cream, sugar. Dog friendly -1 dog if you agree to our rules.

Feb 10 – 17

G$25,850 GYD per night