
House vacation rentals in Mesagne
Find and book unique houses on Airbnb
Quick stats about house rentals in Mesagne

Total vacation rentals
Explore 50 vacation rentals in Mesagne

Nightly prices starting at
Mesagne vacation rentals start at G$6,274 GYD per night before taxes and fees

Verified guest reviews
Over 470 verified reviews to help you choose

Family-friendly vacation rentals
10 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 20 rentals that welcome pets

Rentals with dedicated workspaces
20 properties have a dedicated workspace

Wi-Fi availability
40 of Mesagne vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Mesagne rentals

4.8 Average rating
Mesagne stays are highly rated by guests—averaging 4.8 out of 5!
Top-rated house rentals in Mesagne
Guests agree: these houses are highly rated for location, cleanliness, and more.

L'Angolo di Ostuni – Home & Rooftop
✨️In the heart of the white city, "L'Angolo di Ostuni" is a typical 19th-century house of about 55 square meters, equipped with air conditioning, furnished with original antique Apulian furniture, and with two fabulous bathrooms with chromotherapy. 🏠Very bright and welcoming rooms with three balconies and a magnificent terrace. A short walk from the area closed to vehicle traffic. 🚘There is also public parking near or below the house. 📍It is located in a quiet area but very close to the nightlife and typical clubs. 🛜Free Wi-Fi.
FamilyValueComfort
4.97 out of 5 average rating, 241 reviews
That’s Amore- Design Home&Private Terrace
CIS: BR07401291000000188 CIN (National Identification Code): IT074012B400033730 Experience the magical feeling of being between past and present: it's a historic home! The period floors and stone walls are the backdrop to an environment furnished with design objects, old ceramics and local furniture. The large private terrace, with solarium and hot shower, will excite you: you can relax with a glass of wine at sunset, enjoy the sun on comfortable sunbeds or prepare a dinner in a magical Apulian atmosphere.
LocationFamilyCheck-in
4.99 out of 5 average rating, 204 reviews
I SETTE CONI - TRULLO EDERA
A renovated trullo in a peaceful location in the countryside with authentic style, most of the interiors are recycled or old furniture reinvented in a modern-functional way. Has 1 double bedroom and 1sofabed in the living room.A newly renovated bathroom with shower,fully equipped kitchen,washing machine and lots of space outdoor (one terrace accessible from the bedroom and one on the other side with bbq Access to the swimming pool is shared with the guests of the other 2 properties (no external)
ValueLocationAccess
4.94 out of 5 average rating, 290 reviews
SILVESTRO'S HOUSE - Private house
La Casa di Silvestro is an elegant stone residence, ideal for immersing yourself in the tranquility of the Itria Valley. Two bright and comfortable double bedrooms, a large kitchen, and two private atriums provide an oasis of absolute peace. A single sofa bed is available upon request. The host enhances the stay with tastings of typical products, traditional dishes, extra-virgin olive oil produced from the property's own olive trees, and local wine, for an authentic Apulian culinary experience.
ValueLocationBiking
4.99 out of 5 average rating, 157 reviews
Studio apartment with a star vault
Casa di Enea, a newly renovated studio apartment located on the ground floor of a charming historic building, will welcome you with its magnificent star vault. Equipped with a comfortable double bed located on an elegant mezzanine. The modern and functional bathroom is equipped with a shower and toilet with a built-in bidet. Complete with air conditioning, smart TV, Wi-Fi and a fully equipped kitchen, washer-dryer. In the historic center of Mesagne, but strategically outside the ZTL.
LocationFamilyCleanliness
5.0 out of 5 average rating, 15 reviews
Dimora Flò - Authentic style in the heart of Brindisi
Dimora Flò is an apartment with an authentic character, enhanced by artistic details, evocative colors, and beautiful stone vaults. In the heart of the historic center of Brindisi, it offers a comfortable and relaxing stay, a short walk from the city's main services and attractions. An intimate and welcoming environment, ideal for tourists who want to immerse themselves in the local atmosphere and for professionals looking for comfort and practicality, even during longer stays.
FamilyLocationLong stay
4.96 out of 5 average rating, 120 reviews
Stylish Lovely house with private courtyards
This Lovely house is a cozy historic accommodation, just steps away from the old town center with squares, castles, and restaurants. The lodging offers 5 beds and features a delightful inner courtyard, perfect for outdoor relaxation. Suitable for families or groups of friends, the house combines the charm of ancient Apulian homes with modern comforts. Its strategic location allows easy exploration of the village's beauties and enjoyment of the local culture and cuisine.
LocationAccessCondition
4.86 out of 5 average rating, 22 reviews
Vista Mare Terrace Sunset - Design Retreat Ostuni
Experience unforgettable vacation moments in the heart of Ostuni's Centro Storico. The property features 3 renovated apartments: one on the ground floor &two on the first floor, connected via outdoor stairs. The terrace offers breathtaking views of olive groves & the sea. Ideal for families & couples. All rooms are air-conditioned. Designer furniture & a prime location near Ostuni's attractions & Apulia’s sights. Your dream vacation awaits!
ValueFamilyNearby
4.89 out of 5 average rating, 110 reviews
Casa Sotto L’Arancio • Rustic Townhouse & Pool
Casa Sotto L’Arancio is a serene hideaway in the heart of Carovigno’s historical centre and is located 30 minutes from Brindisi Airport and just 10 minutes to both Ostuni and Puglia’s Adriatic coastline. Once part of a 17th-century monastery, the house has been lovingly restored and features vaulted ceilings, a private courtyard, an outdoor plunge pool and dining space allowing you to live slowly and feel connected to the heart of Puglia.
LocationFamilyDecor
5.0 out of 5 average rating, 18 reviews
Trullo Tulou relax in Valle d'Itria
The apartment is placed in the most privileged area of Itria Valley, between Locorotondo and Alberobello.. The accommodation consists of five ancient "trulli" dating back to the 16th century, renovated and equipped with all necessary amenities, garden and private courtyard, Wi-Fi, gazebo, kitchen and air conditioning and private parking. Ideal if you want to try the unique experience in one of the most impressive historical context!
FamilyLocationLaundry
4.86 out of 5 average rating, 284 reviews
Licia Loft
Loft Licia in the heart of the historic center of Mesagne has just been renovated from a century-old house with exposed star vaults. The steps are original, therefore with significant risers not suitable for people with difficulties. The house has a large double bed 2 meters long and a comfortable sofa bed with an 18 cm mattress. It offers a free pass to park on the blue stripes in the area surrounding the historic center.
LocationValueAccuracy
4.95 out of 5 average rating, 22 reviews
Eden Villa with garden, veranda, reserved parking
At Casa Eden, you can enjoy a relaxing atmosphere and other amenities such as free private parking, a garden, and a covered veranda. It is located at the gates of Mesagne in a quiet residential area. From there, you can reach the best places, such as Alberobello, Ostuni, Lecce, and Gallipoli. A few kilometers away, you can explore naturalistic paths and spend a day by the sea near the Torre Guaceto natural reserve.
ValueLocationComfort
4.98 out of 5 average rating, 52 reviewsPopular amenities for Mesagne house rentals
House rentals with a pool

Trulli di Mezza
FamilyLocationParking
4.96 out of 5 average rating, 160 reviews
TRULLIARCOANTICO-TRULLO QUICKLY
LocationFamilyCheckout
4.94 out of 5 average rating, 256 reviews
Villa Dolce Vita
LocationFamilyBackyard
4.93 out of 5 average rating, 14 reviews
Villa with pool
FamilyLocationQuiet
4.96 out of 5 average rating, 50 reviews
TD Trulli di Carole Renovated Trulli with Pool
LocationValueCleanliness
4.85 out of 5 average rating, 20 reviews
Villa with Pool, Trullo & Panoramic Views | Ostuni
LocationFamilySleep quality
4.93 out of 5 average rating, 55 reviews
Luxury design villa with pool in top location
LocationFamilyQuiet
5.0 out of 5 average rating, 40 reviews
Lamia Filina by BiancoPugliaVacanze
FamilyLocationPool
5.0 out of 5 average rating, 5 reviewsWeekly house rentals

Apulian Vibes (modern villa)
LocationFamilyCheck-in
4.96 out of 5 average rating, 79 reviews
Luxury apartment and terrace
FamilyLocationCheck-in
4.94 out of 5 average rating, 33 reviews
Vacation villa with pool
LocationFamilyGetting around
4.93 out of 5 average rating, 30 reviews
Ca’ Lezet house and rooms
LocationFamilyNearby
4.94 out of 5 average rating, 36 reviews
Wanderlust Experience | L'alcova del Rò
LocationValueAmenities
4.92 out of 5 average rating, 36 reviews
Hélène Luxury Home Suite
LocationValueLaundry
5.0 out of 5 average rating, 19 reviews
Slow life · terrace · 3 min to center · free park
LocationIndoor spacesParking
4.95 out of 5 average rating, 19 reviews
Historic residence in the center of Lecce, panoramic terrace
FamilyLocationQuiet
5.0 out of 5 average rating, 56 reviewsPrivate house rentals

Dimore Mida 17B
LocationBathroomKitchen
4.94 out of 5 average rating, 35 reviews
Lamia del Vespro. For families with children
FamilyLocationAccess
4.97 out of 5 average rating, 60 reviews
Villa Le Ozze
LocationFamilyGrill
5.0 out of 5 average rating, 13 reviews
Farmhouse Citrignano with Private Pool
FamilyLocationCondition
4.91 out of 5 average rating, 81 reviews
La Corte Bianca Luxury Villa.
FamilyLocationQuiet
4.95 out of 5 average rating, 22 reviews
Private pool in Lecce, steps from old town
FamilyLocationCheck-in
4.96 out of 5 average rating, 51 reviews
Casa Emilia 3 bedrooms 4 minutes from OSTUNI
FamilyLocationCleanliness
5.0 out of 5 average rating, 15 reviews
House of the Aragonese, Ostuni
FamilyLocationBathroom
4.96 out of 5 average rating, 51 reviewsWhen is the best time to visit Mesagne?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$16,941 GYD | G$15,895 GYD | G$14,431 GYD | G$14,640 GYD | G$14,849 GYD | G$16,523 GYD | G$19,451 GYD | G$19,451 GYD | G$17,150 GYD | G$16,104 GYD | G$14,640 GYD | G$16,941 GYD |
| Avg. temp | 10°C | 10°C | 12°C | 15°C | 19°C | 23°C | 26°C | 26°C | 23°C | 19°C | 15°C | 11°C |
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- Salento
- Trulli Valle d'Itria
- Baia Dei Turchi
- Punta della suina
- Zoosafari Fasanolandia
- Punta Prosciutto Beach
- Torre Guaceto Beach
- Cala Porta Vecchia
- Torre San Giovanni Beach
- Togo bay la Spiaggia
- Spiaggia Le Dune
- Lama Monachile
- Lido Morelli - Ostuni
- MAR.TA Museo Archeologico Nazionale di Taranto
- Trulli Rione Monti
- Porta Napoli
- Porto Selvaggio Beach
- Spiaggia di Montedarena
- Spiaggia Sant'Isidoro
- Gate Of Saint Blaise
- Castello Aragonese
- Dune Di Campomarino
- Roman Amphitheatre
- Parco naturale regionale Dune costiere da Torre Canne a Torre S.Leonardo





